|
Cymarin
Cymarin (or cymarine) is a cardiac glycoside. Plants of the genus ''Apocynum'', including ''Apocynum cannabinum ''Apocynum cannabinum'' (dogbane, amy root, hemp dogbane, prairie dogbane, Indian hemp, rheumatism root, or wild cotton) is a perennial herbaceous plant that grows throughout much of North America—in the southern half of Canada and throughou ...'' and '' Apocynum venetum'', contain cymarin. Cymarin is a cardiac glycoside and an anti- arrhythmia and cardiotonic agent. References External links * Cardenolides {{cardiovascular-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apocynum
''Apocynum'', commonly known as dogbane or Indian hemp, is a small genus of the flowering plant family Apocynaceae. Its name comes from Ancient Greek , from "away" and "dog", referring to dogbane ('' Cionura erecta''), which was used to poison dogs. The genus is native to North America, temperate Asia, and southeastern Europe. ''Apocynum'' species are used as food plants by the larvae of some Lepidoptera species, including the mouse moth and the queen butterfly. Uses ''Apocynum cannabinum'' was used as a source of fiber by Native Americans. '' Apocynum venetum'' () is used as an herbal tea in China. Dogbane contains cymarin, a cardiotonic agent formerly used to treat cardiac arrhythmia in humans. Species Almost 300 names have been proposed in the genus for species, subspecies, and forms. , only the following five species and hybrids are currently recognized, with several subspecies and varieties accepted for '' A. androsaemifolium'' and '' A. venetum'' (see their respecti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiac Glycoside
Cardiac glycosides are a class of organic compounds that increase the output force of the heart and decrease its rate of contractions by inhibiting the cellular sodium-potassium ATPase pump. Their beneficial medical uses are as treatments for congestive heart failure and cardiac arrhythmias; however, their relative toxicity prevents them from being widely used. Most commonly found as secondary metabolites in several plants such as foxglove plants, these compounds nevertheless have a diverse range of biochemical effects regarding cardiac cell function and have also been suggested for use in cancer treatment. Classification General structure The general structure of a cardiac glycoside consists of a steroid molecule attached to a sugar (glycoside) and an R group. The steroid nucleus consists of four fused rings to which other functional groups such as methyl, hydroxyl, and aldehyde groups can be attached to influence the overall molecule's biological activity. Cardiac glycosi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apocynum Cannabinum
''Apocynum cannabinum'' (dogbane, amy root, hemp dogbane, prairie dogbane, Indian hemp, rheumatism root, or wild cotton) is a perennial herbaceous plant that grows throughout much of North America—in the southern half of Canada and throughout the United States. It is poisonous to humans, dogs, cats, and horses. All parts of the plant are toxic and can cause cardiac arrest if ingested. Some Lepidoptera feed on this plant, such as a hummingbird moth. Description ''Apocynum cannabinum'' grows up to tall. The stems are reddish and contain a milky latex. The leaves are opposite, simple broad lanceolate, long and broad, entire, and smooth on top with white hairs on the underside. It flowers from July to August, has large sepals, and a five-lobed white corolla. The flowers are hermaphrodite, with both male and female organs. Taxonomy Etymology ''Apocynum'' means "poisonous to dogs". The specific epithet ''cannabinum'', and the common names hemp dogbane and Indian hemp refer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apocynum Venetum
''Apocynum venetum'', commonly known as sword-leaf dogbane, is a plant species in the dogbane family, poisonous but used as a source of fiber, medicine, and nectar for production of honey. Distribution and habitat ''Apocynum venetum'' is considered to be native to a wide range in northern Asia and SE Europe: Italy, Bulgaria, Romania, Ex/Yugoslavia, Turkey, Ukraine, Russia, Siberia, Central Asia, Iran, Iraq, Cyprus, Pakistan, Afghanistan, China, and Japan. It grows in swamps, wet places, and maritime sands. Uses ''Apocynum venetum'' fibers can be extracted from the ''A. venetum'' bast; these fibers possess the luster of silk, smoothness of ramie, malleability of cashmere, and the softness of cotton. ''Apocynum venetum'' leaves have been used in the traditional medicine for hypertension Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arrhythmia
Arrhythmias, also known as cardiac arrhythmias, heart arrhythmias, or dysrhythmias, are irregularities in the heartbeat, including when it is too fast or too slow. A resting heart rate that is too fast – above 100 beats per minute in adults – is called tachycardia, and a resting heart rate that is too slow – below 60 beats per minute – is called bradycardia. Some types of arrhythmias have no symptoms. Symptoms, when present, may include palpitations or feeling a pause between heartbeats. In more serious cases, there may be lightheadedness, passing out, shortness of breath or chest pain. While most cases of arrhythmia are not serious, some predispose a person to complications such as stroke or heart failure. Others may result in sudden death. Arrhythmias are often categorized into four groups: extra beats, supraventricular tachycardias, ventricular arrhythmias and bradyarrhythmias. Extra beats include premature atrial contractions, premature ventricular contract ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiotonic
A cardiac stimulant is a substance which acts as a stimulant of the heart – e.g., via positive chronotropic or inotropic action. Examples of cardiac stimulant drugs are cocaine and methamphetamine Methamphetamine (contracted from ) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamph .... References External links * {{cardiovascular-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
.png "Click for more on -> Arrhythmia")