Corticospinal
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Corticospinal
The pyramidal tracts include both the corticobulbar tract and the corticospinal tract. These are aggregations of efferent nerve fibers from the upper motor neurons that travel from the cerebral cortex and terminate either in the brainstem (''corticobulbar'') or spinal cord (''corticospinal'') and are involved in the control of motor functions of the body. The corticobulbar tract conducts impulses from the brain to the cranial nerves. These nerves control the muscles of the face and neck and are involved in facial expression, mastication, swallowing, and other motor functions. The corticospinal tract conducts impulses from the brain to the spinal cord. It is made up of a lateral and anterior tract. The corticospinal tract is involved in voluntary movement. The majority of fibres of the corticospinal tract cross over in the medulla oblongata, resulting in muscles being controlled by the opposite side of the brain. The corticospinal tract contains the axons of the pyramidal cel ...
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Anterior Corticospinal Tract
The anterior corticospinal tract (also called the ventral corticospinal tract, "Bundle of Turck", medial corticospinal tract, direct pyramidal tract, or anterior cerebrospinal fasciculus) is a small bundle of descending fibers that connect the cerebral cortex to the spinal cord. Descending tracts are pathways by which motor signals are sent from upper motor neurons in the brain to lower motor neurons which then directly innervate muscle to produce movement. The anterior corticospinal tract is usually small, varying inversely in size with the lateral corticospinal tract, which is the main part of the corticospinal tract. It lies close to the anterior median fissure, and is present only in the upper part of the spinal cord; gradually diminishing in size as it descends, it ends about the middle of the thoracic region. It consists of descending fibers that arise from cells in the motor area of the ipsilateral cerebral hemisphere. The impulse travels from these upper motor neurons ( ...
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Corticospinal Tract
The corticospinal tract is a white matter motor pathway starting at the cerebral cortex that terminates on lower motor neurons and interneurons in the spinal cord, controlling movements of the limbs and trunk. There are more than one million neurons in the corticospinal tract, and they become myelinated usually in the first two years of life. The corticospinal tract is one of the pyramidal tracts, the other being the corticobulbar tract. Anatomy The corticospinal tract originates in several parts of the brain, including not just the motor areas, but also the primary somatosensory cortex and premotor areas. Most of the neurons originate in the primary motor cortex (precentral gyrus, Brodmann area 4) or the premotor frontal areas.Purves, D. et al. (2012). Neuroscience: Fifth edition. Sunderland, MA: Sinauer Associates, Inc.Kolb, B. & Whishaw, I. Q. (2014). An introduction to brain and behavior: Fourth edition. New York, NY: Worth Publishers. About 30% of corticospinal neurons origi ...
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Medullary Pyramids
In neuroanatomy, the medullary pyramids are paired white matter structures of the brainstem's medulla oblongata that contain motor fibers of the corticospinal and corticobulbar tracts – known together as the pyramidal tracts. The lower limit of the pyramids is marked when the fibers cross ( decussate). Structure The ventral portion of the medulla oblongata contains the medullary pyramids. These two ridge-like structures travel along the length of the medulla oblongata and are bordered medially by the anterior median fissure. They each have an anterolateral sulcus along their lateral borders, where the hypoglossal nerve emerges from. Also at the side of each pyramid there is a pronounced bulge known as an olive. Fibers of the posterior column, which transmit sensory and proprioceptive information, are located behind the pyramids on the medulla oblongata. The medullary pyramids contain motor fibers that are known as the corticobulbar and corticospinal tracts. The cortico ...
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Pyramid (brainstem)
In neuroanatomy, the medullary pyramids are paired white matter structures of the brainstem's medulla oblongata that contain motor fibers of the corticospinal and corticobulbar tracts – known together as the pyramidal tracts. The lower limit of the pyramids is marked when the fibers cross ( decussate). Structure The ventral portion of the medulla oblongata contains the medullary pyramids. These two ridge-like structures travel along the length of the medulla oblongata and are bordered medially by the anterior median fissure. They each have an anterolateral sulcus along their lateral borders, where the hypoglossal nerve emerges from. Also at the side of each pyramid there is a pronounced bulge known as an olive. Fibers of the posterior column, which transmit sensory and proprioceptive information, are located behind the pyramids on the medulla oblongata. The medullary pyramids contain motor fibers that are known as the corticobulbar and corticospinal tracts. The cortico ...
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Lateral Corticospinal Tract
The lateral corticospinal tract (also called the crossed pyramidal tract or lateral cerebrospinal fasciculus) is the largest part of the corticospinal tract. It extends throughout the entire length of the spinal cord, and on transverse section appears as an oval area in front of the posterior column and medial to the posterior spinocerebellar tract. Structure Descending motor pathways carry motor signals from the brain down the spinal cord and to the target muscle or organ. They typically consist of an upper motor neuron and a lower motor neuron. The lateral corticospinal tract is a descending motor pathway that begins in the cerebral cortex, decussates in the pyramids of the lower medulla (also known as the medulla oblongata or the cervicomedullary junction, which is the most posterior division of the brain) and proceeds down the contralateral side of the spinal cord. It is the largest part of the corticospinal tract. It extends throughout the entire length of the medulla spinal ...
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Spinal Cord Tracts
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it ends. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diameter of the spinal cord ranges from in the cervical and lumbar regions to in the thoracic area. The spinal cord functions primarily in the transmission of nerve signals from the motor cortex to the body, ...
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Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it ends. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diameter of the spinal cord ranges from in the cervical and lumbar regions to in the thoracic area. The spinal cord functions primarily in the transmission of nerve signals from the motor cortex to the ...
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Primary Motor Cortex
The primary motor cortex (Brodmann area 4) is a Human brain, brain region that in humans is located in the dorsal portion of the frontal lobe. It is the primary cortex, primary region of the motor system and works in association with other motor areas including premotor cortex, the supplementary motor area, posterior parietal cortex, and several subcortical brain regions, to plan and execute voluntary movements. Primary motor cortex is defined anatomically as the region of cortex that contains large neurons known as Betz cells, which, along with other cortical neurons, send long axons down the spinal cord to synapse onto the interneuron circuitry of the spinal cord and also directly onto the alpha motor neurons in the spinal cord which connect to the muscles. At the primary motor cortex, motor representation is orderly arranged (in an inverted fashion) from the toe (at the top of the cerebral hemisphere) to mouth (at the bottom) along a fold in the cortex called the central sulcu ...
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Supplementary Motor Area
The supplementary motor area (SMA) is a part of the motor cortex of primates that contributes to the control of movement. It is located on the midline surface of the hemisphere just in front of (anterior to) the primary motor cortex leg representation. In monkeys the SMA contains a rough map of the body. In humans the body map is not apparent. Neurons in the SMA project directly to the spinal cord and may play a role in the direct control of movement. Possible functions attributed to the SMA include the postural stabilization of the body, the coordination of both sides of the body such as during bimanual action, the control of movements that are internally generated rather than triggered by sensory events, and the control of sequences of movements. All of these proposed functions remain hypotheses. The precise role or roles of the SMA is not yet known. For the discovery of the SMA and its relationship to other motor cortical areas, see the main article on the motor cortex. Subregi ...
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Internal Capsule
The internal capsule is a white matter structure situated in the inferomedial part of each cerebral hemisphere of the brain. It carries information past the basal ganglia, separating the caudate nucleus and the thalamus from the putamen and the globus pallidus. The internal capsule contains both ascending and descending axons, going to and coming from the cerebral cortex. It also separates the caudate nucleus and the putamen in the dorsal striatum, a brain region involved in motor and reward pathways. The corticospinal tract constitutes a large part of the internal capsule, carrying motor information from the primary motor cortex to the lower motor neurons in the spinal cord. Above the basal ganglia the corticospinal tract is a part of the corona radiata. Below the basal ganglia the tract is called cerebral crus (a part of the cerebral peduncle) and below the pons it is referred to as the corticospinal tract. Structure The internal capsule consists of three parts and is V-sh ...
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Pyramidal Cells
Pyramidal cells, or pyramidal neurons, are a type of multipolar neuron found in areas of the brain including the cerebral cortex, the hippocampus, and the amygdala. Pyramidal neurons are the primary excitation units of the mammalian prefrontal cortex and the corticospinal tract. Pyramidal neurons are also one of two cell types where the characteristic sign, Negri bodies, are found in post-mortem rabies infection. Pyramidal neurons were first discovered and studied by Santiago Ramón y Cajal. Since then, studies on pyramidal neurons have focused on topics ranging from neuroplasticity to cognition. Structure File:GFPneuron.png, Pyramidal neuron visualized by green fluorescent protein (gfp) File:Hippocampal-pyramidal-cell.png, A hippocampal pyramidal cell One of the main structural features of the pyramidal neuron is the conic shaped soma, or cell body, after which the neuron is named. Other key structural features of the pyramidal cell are a single axon, a large apical dendrite, ...
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Corticobulbar Tract
In neuroanatomy, the corticobulbar (or corticonuclear) tract is a two-neuron white matter motor pathway connecting the motor cortex in the cerebral cortex to the medullary pyramids, which are part of the brainstem's medulla oblongata (also called "bulbar") region, and are primarily involved in carrying the motor function of the non-oculomotor cranial nerves. The corticobulbar tract is one of the pyramidal tracts, the other being the corticospinal tract. Structure The corticobulbar tract originates in the primary motor cortex of the frontal lobe, just superior to the lateral fissure and rostral to the central sulcus in the precentral gyrus (Brodmann area 4). The tract descends through the corona radiata and genu of the internal capsule with a few fibers in the posterior limb of the internal capsule, as it passes from the cortex down to the midbrain. In the midbrain, the internal capsule becomes the cerebral peduncles. The white matter is located in the ventral portion of the cere ...
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