Supplementary Motor Area
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Supplementary Motor Area
The supplementary motor area (SMA) is a part of the motor cortex of primates that contributes to the control of movement. It is located on the midline surface of the hemisphere just in front of (anterior to) the primary motor cortex leg representation. In monkeys the SMA contains a rough map of the body. In humans the body map is not apparent. Neurons in the SMA project directly to the spinal cord and may play a role in the direct control of movement. Possible functions attributed to the SMA include the postural stabilization of the body, the coordination of both sides of the body such as during bimanual action, the control of movements that are internally generated rather than triggered by sensory events, and the control of sequences of movements. All of these proposed functions remain hypotheses. The precise role or roles of the SMA is not yet known. For the discovery of the SMA and its relationship to other motor cortical areas, see the main article on the motor cortex. Subregi ...
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Motor Cortex
The motor cortex is the region of the cerebral cortex believed to be involved in the planning, control, and execution of voluntary movements. The motor cortex is an area of the frontal lobe located in the posterior precentral gyrus immediately anterior to the central sulcus. Components of the motor cortex The motor cortex can be divided into three areas: 1. The primary motor cortex is the main contributor to generating neural impulses that pass down to the spinal cord and control the execution of movement. However, some of the other motor areas in the brain also play a role in this function. It is located on the anterior paracentral lobule on the medial surface. 2. The premotor cortex is responsible for some aspects of motor control, possibly including the preparation for movement, the sensory guidance of movement, the spatial guidance of reaching, or the direct control of some movements with an emphasis on control of proximal and trunk muscles of the body. Located anterior ...
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Supplementary Eye Field
Supplementary eye field (SEF) is the name for the anatomical area of the dorsal medial frontal lobe of the primate cerebral cortex that is indirectly involved in the control of saccadic eye movements. Evidence for a supplementary eye field was first shown by Schlag, and Schlag-Rey.Schlag J, Schlag-Rey M.(1987) Evidence for a supplementary eye field. J Neurophysiol. 57(1):179-200. Current research strives to explore the SEF's contribution to visual search and its role in visual salience.Purcell, B. A., Weigand, P. K., & Schall, J. D. (2012). Supplementary Eye Field during Visual Search: Salience, Cognitive Control, and Performance Monitoring. Journal of Neuroscience, 32(30), 10273-10285. doi: Doi 10.1523/Jneurosci.6386-11.2012Stuphorn V, Brown JW, Schall JD. Role of Supplementary Eye Field in Saccade Initiation: Executive, Not Direct, Control. J Neurophysiol. Feb 2010;103(2):801-816 The SEF constitutes together with the frontal eye fields (FEF), the intraparietal sulcus (IPS), ...
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Cytoarchitecture
Cytoarchitecture (Greek '' κύτος''= "cell" + '' ἀρχιτεκτονική''= "architecture"), also known as cytoarchitectonics, is the study of the cellular composition of the central nervous system's tissues under the microscope. Cytoarchitectonics is one of the ways to parse the brain, by obtaining sections of the brain using a microtome and staining them with chemical agents which reveal where different neurons are located. The study of the parcellation of ''nerve fibers'' (primarily axons) into layers forms the subject of myeloarchitectonics (


History of the cerebral cytoarchitecture

Defining cerebral cytoarchitecture began with the advent of —the science of slicing a ...
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Cingulate Sulcus
The cingulate sulcus is a sulcus (brain fold) on the cingulate cortex in the medial wall of the cerebral cortex. The frontal and parietal lobes are separated from the cingulate gyrus by the cingulate sulcus. It terminates as the marginal sulcus of the cingulate sulcus. It sends a ramus to separate the paracentral lobule from the frontal gyri, the paracentral sulcus. Additional images File:Cingulate sulcus animation small.gif, Position of cingulate sulcus (shown in red). File:LobesCaptsMedial1.png, Medial surface of right cerebral hemisphere. Cingulate sulcus (labeled as sulcus cinguli) and brain lobes. File:Slide2ZEN.JPG, Medial surface of cerebral hemisphere.Medial view.Deep dissection. File:Slide3ZEN.JPG, Medial surface of cerebral hemisphere.Medial view.Deep dissection. File:Slide4ZE.JPG, Medial surface of cerebral hemisphere.Medial view.Deep dissection. External links * NIF Search - Cingulate Sulcusvia the Neuroscience Information Framework The Neuroscience Information ...
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Epithalamus
The epithalamus is a posterior (dorsal) segment of the diencephalon. The epithalamus includes the habenular nuclei and their interconnecting fibers, the habenular commissure, the stria medullaris and the pineal gland. Functions The function of the epithalamus is to connect the limbic system to other parts of the brain. The epithalamus also serves as a connecting point for the dorsal diencephalic conduction system, which is responsible for carrying information from the limbic forebrain to limbic midbrain structures. Some functions of its components include the secretion of melatonin and secretion of hormones from the pituitary gland (by the pineal gland circadian rhythms), regulation of motor pathways and emotions, and how energy is conserved in the body. A study has shown that the lateral habenula, an epithalamic structure, produces spontaneous theta oscillatory activity that was correlated with theta oscillation in the hippocampus. The same study also found that the increase i ...
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Putamen
The putamen (; from Latin, meaning "nutshell") is a round structure located at the base of the forebrain (telencephalon). The putamen and caudate nucleus together form the dorsal striatum. It is also one of the structures that compose the basal nuclei. Through various pathways, the putamen is connected to the substantia nigra, the globus pallidus, the claustrum, and the thalamus, in addition to many regions of the cerebral cortex. A primary function of the putamen is to regulate movements at various stages (e.g. preparation and execution) and influence various types of learning. It employs GABA, acetylcholine, and enkephalin to perform its functions. The putamen also plays a role in degenerative neurological disorders, such as Parkinson's disease. History The word "putamen" is from Latin, referring to that which "falls off in pruning", from "putare", meaning "to prune, to think, or to consider". Until recently, most MRI research focused broadly on the basal ganglia as a who ...
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Globus Pallidus
The globus pallidus (GP), also known as paleostriatum or dorsal pallidum, is a subcortical structure of the brain. It consists of two adjacent segments, one external, known in rodents simply as the globus pallidus, and one internal, known in rodents as the entopeduncular nucleus. It is part of the telencephalon, but retains close functional ties with the subthalamus in the diencephalon – both of which are part of the extrapyramidal motor system. The globus pallidus is a major component of the basal ganglia, with principal inputs from the striatum, and principal direct outputs to the thalamus and the substantia nigra. The latter is made up of similar neuronal elements, has similar afferents from the striatum, similar projections to the thalamus, and has a similar synaptology. Neither receives direct cortical afferents, and both receive substantial additional inputs from the intralaminar thalamus. Globus pallidus is Latin for "pale globe". Structure Pallidal nuclei are ma ...
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Caudate Nucleus
The caudate nucleus is one of the structures that make up the corpus striatum, which is a component of the basal ganglia in the human brain. While the caudate nucleus has long been associated with motor processes due to its role in Parkinson's disease, it plays important roles in various other nonmotor functions as well, including procedural learning, associative learning and inhibitory control of action, among other functions. The caudate is also one of the brain structures which compose the reward system and functions as part of the cortico–basal ganglia– thalamic loop. Structure Together with the putamen, the caudate forms the dorsal striatum, which is considered a single functional structure; anatomically, it is separated by a large white matter tract, the internal capsule, so it is sometimes also referred to as two structures: the medial dorsal striatum (the caudate) and the lateral dorsal striatum (the putamen). In this vein, the two are functionally distinct not a ...
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Wilder Penfield
Wilder Graves Penfield (January 26, 1891April 5, 1976) was an American Canadians, American-Physicians in Canada, Canadian neurosurgeon. He expanded brain surgery's methods and techniques, including mapping the functions of various regions of the brain such as the cortical homunculus. His scientific contributions on neural stimulation expand across a variety of topics including hallucinations, illusions, and ''déjà vu''. Penfield devoted much of his thinking to mental processes, including contemplation of whether there was any scientific basis for the existence of the human soul. Biography Early life and education Born in Spokane, Washington, on January 26, 1891, Penfield spent most of his early life in Hudson, Wisconsin. He studied at Princeton University, where he was a member of Cap and Gown Club and played on the Princeton Tigers football, football team. After graduation in 1913, he was hired briefly as the team coach. In 1915 he obtained a Rhodes Scholarship to Merton C ...
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Bereitschaftspotential
In neurology, the Bereitschaftspotential or BP (German for "readiness potential"), also called the pre-motor potential or readiness potential (RP), is a measure of activity in the motor cortex and supplementary motor area of the brain leading up to voluntary muscle movement. The BP is a manifestation of cortical contribution to the pre-motor planning of volitional movement. It was first recorded and reported in 1964 by Hans Helmut Kornhuber and Lüder Deecke at the University of Freiburg in Germany. In 1965 the full publication appeared after many control experiments.; Englisch translation: PDF(accessed October 21, 2016). Discovery In the spring of 1964 Hans Helmut Kornhuber (then docent and chief physician at the department of neurology, head Professor Richard Jung, university hospital Freiburg im Breisgau) and Lüder Deecke (his doctoral student) went for lunch to the 'Gasthaus zum Schwanen' at the foot of the Schlossberg hill in Freiburg. Sitting alone in the beautiful garden t ...
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Michael Graziano
Michael Steven Anthony Graziano (born May 22, 1967) is an American scientist and novelist who is currently a professor of Psychology and Neuroscience at Princeton University.Princeton University, Department of Psychology, Faculty Information
His scientific research focuses on the brain basis of awareness. He has proposed the "attention schema" theory, an explanation of how, and for what adaptive advantage, brains attribute the property of awareness to themselves. His previous work focused on how the

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Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the brain ...
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