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Bereitschaftspotential
In neurology, the Bereitschaftspotential or BP (German for "readiness potential"), also called the pre-motor potential or readiness potential (RP), is a measure of activity in the motor cortex and supplementary motor area of the brain leading up to voluntary muscle movement. The BP is a manifestation of cortical contribution to the pre-motor planning of volitional movement. It was first recorded and reported in 1964 by Hans Helmut Kornhuber and Lüder Deecke at the University of Freiburg in Germany. In 1965 the full publication appeared after many control experiments.; Englisch translation: PDF(accessed October 21, 2016). Discovery In the spring of 1964 Hans Helmut Kornhuber (then docent and chief physician at the department of neurology, head Professor Richard Jung, university hospital Freiburg im Breisgau) and Lüder Deecke (his doctoral student) went for lunch to the 'Gasthaus zum Schwanen' at the foot of the Schlossberg hill in Freiburg. Sitting alone in the beautiful garden t ...
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Bereitschaftspotenzial Fig1
In neurology, the Bereitschaftspotential or BP (German language, German for "readiness potential"), also called the pre-motor potential or readiness potential (RP), is a measure of activity in the motor cortex and supplementary motor area of the brain leading up to voluntary muscle movement. The BP is a manifestation of cortical contribution to the pre-motor planning of volitional movement. It was first recorded and reported in 1964 by Hans Helmut Kornhuber and Lüder Deecke at the Albert Ludwigs University of Freiburg, University of Freiburg in Germany. In 1965 the full publication appeared after many control experiments.; Englisch translation: PDF(accessed October 21, 2016). Discovery In the spring of 1964 Hans Helmut Kornhuber (then docent and chief physician at the department of neurology, head Professor Richard Jung, university hospital Freiburg im Breisgau) and Lüder Deecke (his doctoral student) went for lunch to the 'Gasthaus zum Schwanen' at the foot of the Schlossberg h ...
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Lüder Deecke
Lüder Deecke (; born 22 June 1938) in Lohe-Rickelshof, Germany is a German Austrian neurologist, neuroscientist, teacher and physician whose scientific discoveries have influenced brain research and the treatment and rehabilitation of neurological disorders. Full professor and head, Department of Clinical Neurology at the University of Vienna Medical University of Vienna, professor emeritus since October 2006, Deecke is also head of the Ludwig Boltzmann Institute for Functional Brain Topography and is the author of a number of books and more than 600 publications in the fields of neurology, clinical neurology, neurophysiology, clinical neurophysiology, neurosciences, brain research, movement disorders, etc. His early research with Hans Helmut Kornhuber in the mid-1960s led to the discovery of the Bereitschaftspotential (or readiness potential), which is a measure of neural activity in the brain that precedes voluntary movements. This discovery set an important standard in resea ...
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Hans Helmut Kornhuber
Hans Helmut Kornhuber (24 February 1928 – 30 October 2009) was a German neurologist and neurophysiologist. Biography Hans Helmut Kornhuber was born as the second of three children of Dr. med. Gertrud and Dr. Arnold Kornhuber. He grew up at a small place Methgen near Königsberg. Eight years old he was admitted to the Friedrich Kollegium in Königsberg. Schooltime ended with preliminary maturity in summer 1944. He was interested in chemistry and got into contact with the chemical institute of the University of Königsberg. With the capitulation of Königsberg on 9 April Kornhuber became a soviet prisoner of war for four and a half years. In September 1949 he was discharged and joined his family in Schleswig-Holstein. In October 1949 he passed a second examination for maturity and started to Munich to study chemistry. In spring 1950 he changed from chemistry to medicine because the experience of captivity led him to think what's important in life. From 1949 on Kornhuber ...
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Free Will
Free will is the capacity of agents to choose between different possible courses of action unimpeded. Free will is closely linked to the concepts of moral responsibility, praise, culpability, sin, and other judgements which apply only to actions that are freely chosen. It is also connected with the concepts of advice, persuasion, deliberation, and prohibition. Traditionally, only actions that are freely willed are seen as deserving credit or blame. Whether free will exists, what it is and the implications of whether it exists or not are some of the longest running debates of philosophy and religion. Some conceive of free will as the right to act outside of external influences or wishes. Some conceive free will to be the capacity to make choices undetermined by past events. Determinism suggests that only one course of events is possible, which is inconsistent with a libertarian model of free will. Ancient Greek philosophy identified this issue, which remains a major focus o ...
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Benjamin Libet
Benjamin Libet (; April 12, 1916 – July 23, 2007) was an American neuroscientist who was a pioneer in the field of human consciousness. Libet was a researcher in the physiology department of the University of California, San Francisco. In 2003, he was the first recipient of the ''Virtual Nobel Prize in Psychology'' from the University of Klagenfurt, "for his pioneering achievements in the experimental investigation of consciousness, initiation of action, and free will". Life He was the son of Ukrainian Jewish immigrants. Gamer Libitsky, his paternal grandfather, came to America in 1865 from a town called Brusilov in Ukraine. His mother, Anna Charovsky, emigrated from Kiev in 1913. His parents first met in Chicago. They were married in 1915, and somewhat over nine months later Benjamin was born. He had a brother Meyer, and a sister Dorothy. Libet attended a public elementary school and John Marshall High School. In 1939, Libet graduated from the University of Chicago, where ...
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Contingent Negative Variation
The contingent negative variation (CNV) is a negative slow surface potential, as measured by electroencephalography (EEG), that occurs during the period between a warning stimulus or signal and an imperative ("go") stimulus. The CNV was one of the first event-related potential (ERP) components to be described. The CNV component was first described by W. Grey Walter and colleagues in an article published in Nature in 1964. The importance of this finding was that it was one of the first studies which showed that consistent patterns of the amplitude of electric responses could be obtained from the large background noise which occurs in EEG recordings and that this activity could be related to a cognitive process such as expectancy. Main paradigms In their study, Grey Walter et al. (1964) presented a "warning stimulus" (e.g., a single click or flash of light) to a human subject. The warning stimulus was randomly followed (or not followed) by an "imperative stimulus" (repetitive clic ...
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Supplementary Motor Area
The supplementary motor area (SMA) is a part of the motor cortex of primates that contributes to the control of movement. It is located on the midline surface of the hemisphere just in front of (anterior to) the primary motor cortex leg representation. In monkeys the SMA contains a rough map of the body. In humans the body map is not apparent. Neurons in the SMA project directly to the spinal cord and may play a role in the direct control of movement. Possible functions attributed to the SMA include the postural stabilization of the body, the coordination of both sides of the body such as during bimanual action, the control of movements that are internally generated rather than triggered by sensory events, and the control of sequences of movements. All of these proposed functions remain hypotheses. The precise role or roles of the SMA is not yet known. For the discovery of the SMA and its relationship to other motor cortical areas, see the main article on the motor cortex. Subregi ...
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Event-related Potential
An event-related potential (ERP) is the measured brain response that is the direct result of a specific sense, sensory, cognition, cognitive, or motor system, motor event. More formally, it is any stereotyped electrophysiology, electrophysiological response to a stimulus. The study of the brain in this way provides a Invasiveness of surgical procedures, noninvasive means of evaluating brain functioning. ERPs are measured by means of electroencephalography (EEG). The magnetoencephalography (MEG) equivalent of ERP is the ERF, or event-related field. Evoked potentials and induced potentials are subtypes of ERPs. History With the discovery of the electroencephalogram (EEG) in 1924, Hans Berger revealed that one could measure the electrical activity of the human brain by placing electrodes on the scalp and amplifying the signal. Changes in voltage can then be plotted over a period of time. He observed that the voltages could be influenced by external events that stimulated the sens ...
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Bayesian Network
A Bayesian network (also known as a Bayes network, Bayes net, belief network, or decision network) is a probabilistic graphical model that represents a set of variables and their conditional dependencies via a directed acyclic graph (DAG). Bayesian networks are ideal for taking an event that occurred and predicting the likelihood that any one of several possible known causes was the contributing factor. For example, a Bayesian network could represent the probabilistic relationships between diseases and symptoms. Given symptoms, the network can be used to compute the probabilities of the presence of various diseases. Efficient algorithms can perform inference and learning in Bayesian networks. Bayesian networks that model sequences of variables (''e.g.'' speech signals or protein sequences) are called dynamic Bayesian networks. Generalizations of Bayesian networks that can represent and solve decision problems under uncertainty are called influence diagrams. Graphical mode ...
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Electromyography
Electromyography (EMG) is a technique for evaluating and recording the electrical activity produced by skeletal muscles. EMG is performed using an instrument called an electromyograph to produce a record called an electromyogram. An electromyograph detects the electric potential generated by muscle cells when these cells are electrically or neurologically activated. The signals can be analyzed to detect abnormalities, activation level, or recruitment order, or to analyze the biomechanics of human or animal movement. Needle EMG is an electrodiagnostic medicine technique commonly used by neurologists. Surface EMG is a non-medical procedure used to assess muscle activation by several professionals, including physiotherapists, kinesiologists and biomedical engineers. In Computer Science, EMG is also used as middleware in gesture recognition towards allowing the input of physical action to a computer as a form of human-computer interaction. Clinical uses EMG testing has a variety of ...
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Electroencephalography
Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in the neocortex and allocortex. It is typically non-invasive, with the EEG electrodes placed along the scalp (commonly called "scalp EEG") using the International 10-20 system, or variations of it. Electrocorticography, involving surgical placement of electrodes, is sometimes called " intracranial EEG". Clinical interpretation of EEG recordings is most often performed by visual inspection of the tracing or quantitative EEG analysis. Voltage fluctuations measured by the EEG bioamplifier and electrodes allow the evaluation of normal brain activity. As the electrical activity monitored by EEG originates in neurons in the underlying brain tissue, the recordings made by the electrodes on the surface of the scalp vary in accordance with their orientation and ...
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