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Comparative Medicine
Comparative medicine is a distinct discipline of experimental medicine that uses animal models of human and animal disease in translational and biomedical research. In other words, it relates and leverages biological similarities and differences among species to better understand the mechanism of human and animal disease. It has also been defined as a study of similarities and differences between human and veterinary medicine including the critical role veterinarians, animal resource centers, and Institutional Animal Care and Use Committees play in facilitating and ensuring humane and reproducible lab animal care and use. The discipline has been instrumental in many of humanity's most important medical advances. History The ancient world The first documented mention of comparative pathology comes from Hippocrates (460 - 370 BCE) in '' Airs, Waters, Places'' where he describes relevant case histories for horse herds and human populations. He insists that diagnosis be based ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Experimental Medicine
An experimental drug is a medicinal product (a drug or vaccine) that has not yet received approval from governmental regulatory authorities for routine use in human or veterinary medicine. A medicinal product may be approved for use in one disease or condition but still be considered experimental for other diseases or conditions. In 2018 the United States of America signed the legislation "Right to Try", this allows individuals who fit into the criteria to try experimental drugs that are not yet deemed safe. In the United States, the body responsible for approval is the U.S. Food and Drug Administration (FDA), which must grant the substance Investigational New Drug (IND) status before it can be tested in human clinical trials. IND status requires the drug's sponsor to submit an IND application that includes data from laboratory and animal testing for safety and efficacy. A drug that is made from a living organism or its products undergoes the same approval process but is called ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germ Theory Of Disease
The germ theory of disease is the currently accepted scientific theory for many diseases. It states that microorganisms known as pathogens or "germs" can lead to disease. These small organisms, too small to be seen without magnification, invade humans, other animals, and other living hosts. Their growth and reproduction within their hosts can cause disease. "Germ" refers to not just a bacterium but to any type of microorganism, such as protists or fungi, or even non-living pathogens that can cause disease, such as viruses, prions, or viroids. Diseases caused by pathogens are called infectious diseases. Even when a pathogen is the principal cause of a disease, environmental and hereditary factors often influence the severity of the disease, and whether a potential host individual becomes infected when exposed to the pathogen. Pathogens are disease-carrying agents that can pass from one individual to another, both in humans and animals. Infectious diseases are caused by biologica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
René Descartes
René Descartes ( or ; ; Latinized: Renatus Cartesius; 31 March 1596 – 11 February 1650) was a French philosopher, scientist, and mathematician, widely considered a seminal figure in the emergence of modern philosophy and science. Mathematics was central to his method of inquiry, and he connected the previously separate fields of geometry and algebra into analytic geometry. Descartes spent much of his working life in the Dutch Republic, initially serving the Dutch States Army, later becoming a central intellectual of the Dutch Golden Age. Although he served a Protestant state and was later counted as a deist by critics, Descartes considered himself a devout Catholic. Many elements of Descartes' philosophy have precedents in late Aristotelianism, the revived Stoicism of the 16th century, or in earlier philosophers like Augustine. In his natural philosophy, he differed from the schools on two major points: first, he rejected the splitting of corporeal substa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middle Ages
In the history of Europe, the Middle Ages or medieval period lasted approximately from the late 5th to the late 15th centuries, similar to the post-classical period of global history. It began with the fall of the Western Roman Empire and transitioned into the Renaissance and the Age of Discovery. The Middle Ages is the middle period of the three traditional divisions of Western history: classical antiquity, the medieval period, and the modern period. The medieval period is itself subdivided into the Early, High, and Late Middle Ages. Population decline, counterurbanisation, the collapse of centralized authority, invasions, and mass migrations of tribes, which had begun in late antiquity, continued into the Early Middle Ages. The large-scale movements of the Migration Period, including various Germanic peoples, formed new kingdoms in what remained of the Western Roman Empire. In the 7th century, North Africa and the Middle East—most recently part of the Ea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monotheistic
Monotheism is the belief that there is only one deity, an all-supreme being that is universally referred to as God. Cross, F.L.; Livingstone, E.A., eds. (1974). "Monotheism". The Oxford Dictionary of the Christian Church (2 ed.). Oxford: Oxford University Press. A distinction may be made between exclusive monotheism, in which the one God is a singular existence, and both inclusive and pluriform monotheism, in which multiple gods or godly forms are recognized, but each are postulated as extensions of the same God. Monotheism is distinguished from henotheism, a religious system in which the believer worships one God without denying that others may worship different gods with equal validity, and monolatrism, the recognition of the existence of many gods but with the consistent worship of only one deity. The term ''monolatry'' was perhaps first used by Julius Wellhausen. Monotheism characterizes the traditions of Bábism, the Baháʼí Faith, Cheondoism, Christianity,Christia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Publius Flavius Vegetius Renatus
Publius (or Flavius) Vegetius Renatus, known as Vegetius (), was a writer of the Later Roman Empire (late 4th century). Nothing is known of his life or station beyond what is contained in his two surviving works: ''Epitoma rei militaris'' (also referred to as ''De re militari''), and the lesser-known ''Digesta Artis Mulomedicinae'', a guide to veterinary medicine. He identifies himself in the opening of his work ''Epitoma rei militaris'' as a Christian. Dating of work The latest event alluded to in his ''Epitoma rei militaris'' is the death of the Emperor Gratian (383); the earliest attestation of the work is a ''subscriptio'' by Flavius Eutropius, writing in Constantinople in 450, which appears in one of two families of manuscripts, suggesting that a division of the manuscript tradition had already occurred. Despite Eutropius' location in Constantinople, the scholarly consensus is that Vegetius wrote in the Western Roman Empire.Walter Goffart. The date and purposes of Vegetius' D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barbary Macaques In Gibraltar
Originally from the Atlas Mountains and the Rif Mountains of Morocco, the Barbary macaque population in Gibraltar is the only wild monkey population on the European continent. Although most Barbary monkey populations in Africa are experiencing decline due to hunting and deforestation, the Gibraltar population is increasing. , some 300 animals in five troops occupy the Upper Rock area of the Gibraltar Nature Reserve, though they make occasional forays into the town. As they are a tailless species, they are also known locally as Barbary apes or rock apes, despite being classified as monkeys (''Macaca sylvanus''). Spanish speakers simply refer to them as ''monos'' () when conversing in Spanish, although English is the native language as the area is a British overseas territory. Origin The name Barbary refers to the Berber People of North Africa who, since the beginning of history, had ties with the animals surrounding their region, as the Barbary macaques. The macaque populati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Dissection
Dissection (from Latin ' "to cut to pieces"; also called anatomization) is the dismembering of the body of a deceased animal or plant to study its anatomical structure. Autopsy is used in pathology and forensic medicine to determine the cause of death in humans. Less extensive dissection of plants and smaller animals preserved in a formaldehyde solution is typically carried out or demonstrated in biology and natural science classes in middle school and high school, while extensive dissections of cadavers of adults and children, both fresh and preserved are carried out by medical students in medical schools as a part of the teaching in subjects such as anatomy, pathology and forensic medicine. Consequently, dissection is typically conducted in a morgue or in an anatomy lab. Dissection has been used for centuries to explore anatomy. Objections to the use of cadavers have led to the use of alternatives including virtual dissection of computer models. Overview Plant and animal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Galenic Formulation
Galenic formulation deals with the principles of preparing and compounding medicines in order to optimize their absorption. Galenic formulation is named after Claudius Galen, a 2nd Century AD Greek physician, who codified the preparation of drugs using multiple ingredients. Today, galenic formulation is part of pharmaceutical formulation. The pharmaceutical formulation of a medicine affects the pharmacokinetics, pharmacodynamics and safety profile of a drug. See also * Formulations * Pharmaceutical formulation * ADME * Pharmacology * Medicinal chemistry * Pesticide formulation The biological activity of a pesticide, be it chemical or biological in nature, is determined by its active ingredient (AI - also called the ''active substance''). Pesticide products very rarely consist of pure technical material. The AI is usually ... Medicinal chemistry {{medicinal-chem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Claudius Galen
Aelius Galenus or Claudius Galenus ( el, Κλαύδιος Γαληνός; September 129 – c. AD 216), often Anglicized as Galen () or Galen of Pergamon, was a Greek physician, surgeon and philosopher in the Roman Empire. Considered to be one of the most accomplished of all medical researchers of antiquity, Galen influenced the development of various scientific disciplines, including anatomy, physiology, pathology, pharmacology, and neurology, as well as philosophy and logic. The son of Aelius Nicon, a wealthy Greek architect with scholarly interests, Galen received a comprehensive education that prepared him for a successful career as a physician and philosopher. Born in the ancient city of Pergamon (present-day Bergama, Turkey), Galen traveled extensively, exposing himself to a wide variety of medical theories and discoveries before settling in Ancient Rome, Rome, where he served prominent members of Roman society and eventually was given the position of personal physician ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poison
Poison is a chemical substance that has a detrimental effect to life. The term is used in a wide range of scientific fields and industries, where it is often specifically defined. It may also be applied colloquially or figuratively, with a broad sense. Whether something is considered a poison may change depending on the amount, the circumstances, and what living things are present. Poisoning could be accidental or deliberate, and if the cause can be identified there may be ways to neutralise the effects or minimise the symptoms. In biology, a poison is a chemical substance causing death, injury or harm to organisms or their parts. In medicine, poisons are a kind of toxin that are delivered passively, not actively. In industry the term may be negative, something to be removed to make a thing safe, or positive, an agent to limit unwanted pests. In ecological terms, poisons introduced into the environment can later cause unwanted effects elsewhere, or in other parts of the food ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cupping Therapy
Cupping therapy is a form of alternative medicine in which a local suction is created on the skin with the application of heated cups. Its practice mainly occurs in Asia but also in Eastern Europe, the Middle East, and Latin America. Cupping has been characterized as a pseudoscience and its practice as quackery. Cupping practitioners attempt to use cupping therapy for a wide array of medical conditions including fevers, chronic low back pain, poor appetite, indigestion, high blood pressure, acne, atopic dermatitis, psoriasis, anemia, stroke rehabilitation, nasal congestion, infertility, and menstrual period cramping. Despite the numerous ailments for which practitioners claim cupping therapy is useful, there is insufficient evidence it has any health benefits, and there are some risks of harm, especially from wet cupping and fire cupping. Bruising and skin discoloration are among the adverse effects of cupping and are sometimes mistaken for child abuse. In rare instances, the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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