Coccidioides
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Coccidioides
''Coccidioides'' is a genus of dimorphic ascomycetes in the family Onygenaceae. Member species are the cause of coccidioidomycosis, also known as San Joaquin Valley fever, an infectious fungal disease largely confined to the Western Hemisphere and endemic in the Southwestern United States. The host acquires the disease by respiratory inhalation of spores disseminated in their natural habitat. The causative agents of coccidioidomycosis are ''Coccidioides immitis'' and ''Coccidioides posadasii''. Both ''C. immitis'' and ''C. posadasii'' are indistinguishable during laboratory testing and commonly referred in literature as ''Coccidioides''. Clinical presentation Coccidioidomycosis is amazingly diverse in terms of its scope of clinical presentation, as well as clinical severity. About 60% of ''Coccidioides'' infections as determined by serologic conversion are asymptomatic. The most common clinical syndrome in the other 40% of infected patients is an acute respiratory i ...
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Coccidioidomycosis
Coccidioidomycosis (, ), commonly known as cocci, Valley fever, as well as California fever, desert rheumatism, or San Joaquin Valley fever, is a mammalian fungal disease caused by '' Coccidioides immitis'' or ''Coccidioides posadasii''. Coccidioidomycosis is endemic in certain parts of the United States in Arizona, California, Nevada, New Mexico, Texas, Utah, and northern Mexico. ''C. immitis'' is a dimorphic saprophytic fungus that grows as a mycelium in the soil and produces a spherule form in the host organism. It resides in the soil in certain parts of the southwestern United States, most notably in California and Arizona. It is also commonly found in northern Mexico, and parts of Central and South America. ''C. immitis'' is dormant during long dry spells, then develops as a mold with long filaments that break off into airborne spores when it rains. The spores, known as arthroconidia, are swept into the air by disruption of the soil, such as during construction, farmin ...
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Coccidioides Histosporocellularis
''Coccidioides'' is a genus of dimorphic ascomycetes in the family Onygenaceae. Member species are the cause of coccidioidomycosis, also known as San Joaquin Valley fever, an infectious fungal disease largely confined to the Western Hemisphere and endemic in the Southwestern United States. The host acquires the disease by respiratory inhalation of spores disseminated in their natural habitat. The causative agents of coccidioidomycosis are ''Coccidioides immitis'' and ''Coccidioides posadasii''. Both ''C. immitis'' and ''C. posadasii'' are indistinguishable during laboratory testing and commonly referred in literature as ''Coccidioides''. Clinical presentation Coccidioidomycosis is amazingly diverse in terms of its scope of clinical presentation, as well as clinical severity. About 60% of ''Coccidioides'' infections as determined by serologic conversion are asymptomatic. The most common clinical syndrome in the other 40% of infected patients is an acute respiratory i ...
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Coccidioides Immitis
''Coccidioides immitis'' is a pathogenic fungus that resides in the soil in certain parts of the southwestern United States, northern Mexico, and a few other areas in the Western Hemisphere. Epidemiology ''C. immitis'', along with its relative '' C. posadasii'', is most commonly seen in the desert regions of the southwestern United States, including certain areas of Arizona, California, New Mexico, Nevada, Texas, and Utah; and in Central and South America in Argentina, Brazil, Colombia, Guatemala, Honduras, Mexico, Nicaragua, Paraguay, and Venezuela. Precise location ''C. immitis'' is largely found in California, but also Baja California and Arizona, while ''C. posadasii'' is regularly found in Texas, northern Mexico and in Central and South America. Both ''C. immitis'' and ''C. posadasii'' are present in Arizona.Hospenthal, Duane R., and Michael G. Rinaldi. Diagnosis and Treatment of Human Mycoses. Totowa, N.J.: Humana Press, 2007, p. 296-297. C. immitis is more common west ...
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Coccidioides Rosea
''Coccidioides'' is a genus of dimorphic ascomycetes in the family Onygenaceae. Member species are the cause of coccidioidomycosis, also known as San Joaquin Valley fever, an infectious fungal disease largely confined to the Western Hemisphere and endemic in the Southwestern United States. The host acquires the disease by respiratory inhalation of spores disseminated in their natural habitat. The causative agents of coccidioidomycosis are ''Coccidioides immitis'' and ''Coccidioides posadasii''. Both ''C. immitis'' and ''C. posadasii'' are indistinguishable during laboratory testing and commonly referred in literature as ''Coccidioides''. Clinical presentation Coccidioidomycosis is amazingly diverse in terms of its scope of clinical presentation, as well as clinical severity. About 60% of ''Coccidioides'' infections as determined by serologic conversion are asymptomatic. The most common clinical syndrome in the other 40% of infected patients is an acute respiratory i ...
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Coccidioides Esteriformis
''Coccidioides'' is a genus of dimorphic ascomycetes in the family Onygenaceae. Member species are the cause of coccidioidomycosis, also known as San Joaquin Valley fever, an infectious fungal disease largely confined to the Western Hemisphere and endemic in the Southwestern United States. The host acquires the disease by respiratory inhalation of spores disseminated in their natural habitat. The causative agents of coccidioidomycosis are ''Coccidioides immitis'' and ''Coccidioides posadasii''. Both ''C. immitis'' and ''C. posadasii'' are indistinguishable during laboratory testing and commonly referred in literature as ''Coccidioides''. Clinical presentation Coccidioidomycosis is amazingly diverse in terms of its scope of clinical presentation, as well as clinical severity. About 60% of ''Coccidioides'' infections as determined by serologic conversion are asymptomatic. The most common clinical syndrome in the other 40% of infected patients is an acute respiratory i ...
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Coccidioides Posadasii
''Coccidioides posadasii'' is a pathogenic fungus that, along with ''Coccidioides immitis'', is the causative agent of coccidioidomycosis, or valley fever in humans. It resides in the soil in certain parts of the Southwestern United States, northern Mexico, and some other areas in the Americas, but its evolution was connected to its animal hosts. ''C. posadasii'' and ''C. immitis'' are morphologically identical, but genetically and epidemiologically distinct. ''C. posadasii'' was identified as a separate species other than ''C. immitis'' in 2002 after a phylogenetic analysis. The two species can be distinguished by DNA polymorphisms and different rates of growth in the presence of high salt concentrations: ''C. posadasii'' grows more slowly. It also differs epidemiologically, since it is found outside the San Joaquin Valley. Unlike ''C. immitis'', which is geographically largely limited to California, ''C. posadasii'' can also be found in northern Mexico and South America. Ear ...
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Dimorphic Fungus
Dimorphic fungi are fungi that can exist in the form of both mold and yeast. This is usually brought about by change in temperature and the fungi are also described as thermally dimorphic fungi. An example is ''Talaromyces marneffei'', a human pathogen that grows as a mold at room temperature, and as a yeast at human body temperature. The term dimorphic is commonly used for fungi that can grow both as yeast and filamentous cells, however many of these dimorphic fungi actually can grow in more than these two forms. Dimorphic is thus often used as a general reference for fungi being able to switch between yeast and filamentous cells, but not necessary limiting more shapes. Ecology of dimorphic fungi Several species of dimorphic fungi are important pathogens of humans and other animals, including ''Coccidioides immitis'', ''Paracoccidioides brasiliensis'', ''Candida albicans'', ''Blastomyces dermatitidis'', ''Histoplasma capsulatum'', '' Sporothrix schenckii'', and ''Emmonsia'' ...
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Classification Of Pneumonia
Pneumonia can be classified in several ways, most commonly by where it was acquired (hospital versus community), but may also by the area of lung affected or by the causative organism. There is also a combined clinical classification, which combines factors such as age, risk factors for certain microorganisms, the presence of underlying lung disease or systemic disease and whether the person has recently been hospitalized. By location acquired Community-acquired Community-acquired pneumonia (CAP) is infectious pneumonia in a person who has not recently been hospitalized. CAP is the most common type of pneumonia. The most common causes of CAP vary depending on a person's age, but they include ''Streptococcus pneumoniae'', viruses, the atypical bacteria, and ''Haemophilus influenzae''. Overall, ''Streptococcus pneumoniae'' is the most common cause of community-acquired pneumonia worldwide. Gram-negative bacteria cause CAP in certain at-risk populations. CAP is the fourth most comm ...
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Ascomycota
Ascomycota is a phylum of the kingdom Fungi that, together with the Basidiomycota, forms the subkingdom Dikarya. Its members are commonly known as the sac fungi or ascomycetes. It is the largest phylum of Fungi, with over 64,000 species. The defining feature of this fungal group is the " ascus" (), a microscopic sexual structure in which nonmotile spores, called ascospores, are formed. However, some species of the Ascomycota are asexual, meaning that they do not have a sexual cycle and thus do not form asci or ascospores. Familiar examples of sac fungi include morels, truffles, brewers' and bakers' yeast, dead man's fingers, and cup fungi. The fungal symbionts in the majority of lichens (loosely termed "ascolichens") such as '' Cladonia'' belong to the Ascomycota. Ascomycota is a monophyletic group (it contains all descendants of one common ancestor). Previously placed in the Deuteromycota along with asexual species from other fungal taxa, asexual (or anamorphic) ascomycet ...
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Coccidia
Coccidia (Coccidiasina) are a subclass of microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida. As obligate intracellular parasites, they must live and reproduce within an animal cell. Coccidian parasites infect the intestinal tracts of animals, and are the largest group of apicomplexan protozoa. Infection with these parasites is known as coccidiosis. Coccidia can infect all mammals, some birds, some fish, some reptiles, and some amphibians. Most species of coccidia are species-specific in their host. An exception is ''Toxoplasma gondii'', which can infect all mammals, although it can only undergo sexual reproduction in cats. Depending on the species of coccidia, infection can cause fever, vomiting, diarrhea, muscle pain, and nervous system effects and changes to behavior, and may lead to death. Healthy adults may recover without medication—but those who are immunocompromised or young almost certainly requ ...
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Onygenaceae
The Onygenaceae are a family of fungi in the Ascomycota, class Eurotiomycetes. Genera These are the genera that are in the Onygenaceae, according to a 2021 review of fungal classification. Following the genus name is the taxonomic authority (those who first circumscribed the genus; standardized author abbreviations are used), year of publication, and the estimated number of species. * '' Amauroascus'' – 15 spp. * '' Aphanoascus'' – 18 spp. * '' Apinisia'' – 3 spp. * '' Arachnotheca'' – 1 sp. * '' Ascocalvatia'' – 1 sp. * '' Auxarthron'' – 13 spp. * '' Auxarthronopsis'' – 2 spp. * '' Bifidocarpus'' – 2 spp. * '' Byssoonygena'' – 1 sp. * '' Canomyces'' – 1 sp. * '' Castanedomyces'' – 1 sp. * '' Chlamydosauromyces'' – 1 sp. * '' Chrysosporium'' – 66 spp. * ''Coccidioides'' – 6 spp. * '' Currahomyces'' – 1 sp. * ''Kuehniella ''Kuehniella'' is a genus of fungi within the Onygenaceae family. The genus name of ''Kuehniella'' is in hono ...
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Onygenales
The Onygenales are an order of fungi in the class Eurotiomycetes and division Ascomycota. The order's last common ancestor is estimated to have lived 150 million years ago. Onygenales can consume and break down keratin, the main component of the outer layer of skin. They are primarily found on animals, droppings, and areas frequented by animals. Many are dimorphic, and can change from mold to yeast form depending on their environment. Many onygenalean fungi are pathogens. One species, ''Trichophyton rubrum'', is the primary cause of athlete's foot. This order also includes Coccidioides implicated in Valley fever. The Onygenales are important as emerging human pathogens because of the rising rates of immunosuppression due to live-organ transplant, HIV/AIDS, and autoimmune disorders such as lupus erythematosus Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. Symptoms of these disease ...
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