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Circumcised
Circumcision is a surgical procedure, procedure that removes the foreskin from the human penis. In the most common form of the operation, the foreskin is extended with forceps, then a circumcision device may be placed, after which the foreskin is wikt:excise, excised. Topical or locally injected anesthesia is generally used to reduce pain and stress (physiology), physiologic stress. It is usually elective surgery, elective, performed as preventive healthcare, a Religious law, religious rite, or Culture, cultural practice. It is also an option for cases of phimosis, other Pathology, pathologies that do not resolve with other treatments, and chronic urinary tract infections (UTIs). The procedure is contraindicated in cases of certain genital structure abnormalities or poor general health. Circumcision is associated with reduced rates of sexually transmitted infections and urinary tract infections. This includes decreasing the incidence of Carcinogenesis, cancer-causing forms of ...
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Foreskin
In male human anatomy, the foreskin, also known as the prepuce, is the double-layered fold of skin, mucosal and muscular tissue at the distal end of the human penis that covers the glans and the urinary meatus. The foreskin is attached to the glans by an elastic band of tissue, known as the frenulum. The outer skin of the foreskin meets with the inner preputial mucosa at the area of the mucocutaneous junction. The foreskin is mobile, fairly stretchable and sustains the glans in a moist environment. Except for humans, a similar structure, known as penile sheath, appears in the male sexual organs of all primates and the vast majority of mammals. In humans, foreskin length varies widely and coverage of the glans in a flaccid and erect state can also vary. The foreskin is fused to the glans at birth and is generally not retractable in infancy and early childhood. Inability to retract the foreskin in childhood should not be considered a problem unless there are other symptoms. Retr ...
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Phimosis
Phimosis (from Greek language, Greek φίμωσις ''phimōsis'' 'muzzling'.) is a condition in which the foreskin of the Human penis, penis cannot stretch to allow it to be pulled back past the Glans penis, glans. A balloon-like swelling under the foreskin may occur with urination. In teenagers and adults, it may result in pain during an erection, but is otherwise not painful. Those affected are at greater risk of inflammation of the glans, known as balanitis, and other complications. In young children, it is normal not to be able to pull back the foreskin at all. Over 90% of cases resolve by the age of seven, although full retraction is still prevented by preputial adhesions in over half at this age. Occasionally, phimosis may be caused by an underlying condition such as scarring due to balanitis or balanitis xerotica obliterans. This can typically be diagnosed by seeing scarring of the opening of the foreskin. Typically, the condition resolves without treatment by the age ...
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Meatal Stenosis
Urethral meatal stenosis is a narrowing (stenosis) of the opening of the urethra at the external urinary meatus, meatus , thus constricting the opening through which urine leaves the body from the urinary bladder. Symptoms and signs * Abnormal strength and direction of urinary stream * Visible narrow opening at the meatus in boys * Irritation, scarring or swelling of the meatus in boys * Discomfort with urination (dysuria and frequency) * Urinary incontinence, Incontinence (day or night) * Bleeding (hematuria) at end of urination * Urinary tract infections - increased susceptibility due to stricture Causes The protection provided by the foreskin for the glans penis and urinary meatus, meatus has been recognized since 1915. In the absence of the foreskin the meatus is exposed to mechanical and chemical irritation from ammoniacal diaper (nappy) that produces blister formation and ulceration of the urethral opening, which eventually gives rise to meatal stenosis (a narrowing of t ...
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Human Penis
The human penis is an external male intromittent organ that additionally serves as the urinary duct. The main parts are the root (radix); the body (corpus); and the epithelium of the penis including the shaft skin and the foreskin (prepuce) covering the glans penis. The body of the penis is made up of three columns of tissue: two corpora cavernosa on the dorsal side and corpus spongiosum between them on the ventral side. The human male urethra passes through the prostate gland, where it is joined by the ejaculatory duct, and then through the penis. The urethra traverses the corpus spongiosum, and its opening, the meatus (), lies on the tip of the glans penis. It is a passage both for urination and ejaculation of semen (''see'' male reproductive system.) Most of the penis develops from the same embryonic tissue as the clitoris in females. The skin around the penis and the urethra share the same embryonic origin as the labia minora in females. An erection is the stiffening e ...
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Urinary Tract Infection
A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects the lower urinary tract it is known as a bladder infection (cystitis) and when it affects the upper urinary tract it is known as a kidney infection (pyelonephritis). Symptoms from a lower urinary tract infection include pain with urination, frequent urination, and feeling the need to urinate despite having an empty bladder. Symptoms of a kidney infection include fever and flank pain usually in addition to the symptoms of a lower UTI. Rarely the urine may appear bloody. In the very old and the very young, symptoms may be vague or non-specific. The most common cause of infection is ''Escherichia coli'', though other bacteria or fungi may sometimes be the cause. Risk factors include female anatomy, sexual intercourse, diabetes, obesity, and family history. Although sexual intercourse is a risk factor, UTIs are not classified as sexually transmitted infections (STIs). Kidney ...
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Penile Cancer
Penile cancer is cancer that develops in the skin or tissues of the penis. Symptoms may include abnormal growth, an ulcer or sore on the skin of the penis, and bleeding or foul smelling discharge. Risk factors include phimosis (inability to retract foreskin of the penis), chronic inflammation, smoking, HPV infection, condylomata acuminate, having multiple sexual partners, and early age of sexual intercourse. Around 95% of penile cancers are squamous cell carcinomas. Other types of penile cancer such as Merkel cell carcinoma, small cell carcinoma, and melanoma are generally rare. In 2020, it occurred in 36,000 men and caused 13,000 deaths. Signs and symptoms Penile cancer can present as redness and irritation on the penis with a skin thickening on the glans or inner foreskin or an ulcerative, outward growingexophytic or “finger-like” (papillary) growth. Penile cancer may accompany penile discharge with or without difficulty or burning or tingling while urinating (dysuria) and ...
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1850s
The 1850s (pronounced "eighteen-fifties") was a decade of the Gregorian calendar that began on January 1, 1850, and ended on December 31, 1859. It was a very turbulent decade, as wars such as the Crimean War, shifted and shook European politics, as well as the expansion of colonization towards the Far East, which also sparked conflicts like the Second Opium War. In the meantime, the United States saw its peak on mass migration to the American West, that particularly made the nation experience an economic boom, as well as a rapidly increasing population. Wars * Crimean War (1854–56) fought between Imperial Russia and an alliance consisting of the United Kingdom of Great Britain and Ireland, the Second French Empire, the Kingdom of Sardinia and the Ottoman Empire. The majority of the conflict takes place around Crimea, on the northern coasts of the Black Sea. * On 8 October 1856 the Second Opium War between several western powers and China begins with the ''Arrow Inc ...
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England
England is a country that is part of the United Kingdom. It shares land borders with Wales to its west and Scotland to its north. The Irish Sea lies northwest and the Celtic Sea to the southwest. It is separated from continental Europe by the North Sea to the east and the English Channel to the south. The country covers five-eighths of the island of Great Britain, which lies in the North Atlantic, and includes over 100 smaller islands, such as the Isles of Scilly and the Isle of Wight. The area now called England was first inhabited by modern humans during the Upper Paleolithic period, but takes its name from the Angles, a Germanic tribe deriving its name from the Anglia peninsula, who settled during the 5th and 6th centuries. England became a unified state in the 10th century and has had a significant cultural and legal impact on the wider world since the Age of Discovery, which began during the 15th century. The English language, the Anglican Church, and Engli ...
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Joint United Nations Programme On HIV/AIDS
The Joint United Nations Programme on HIV and AIDS (UNAIDS) (, ONUSIDA) is the main advocate for accelerated, comprehensive and coordinated global action on the HIV/AIDS pandemic. The mission of UNAIDS is to lead, strengthen and support an expanded response to HIV and AIDS that includes preventing transmission of HIV, providing care and support to those already living with the virus, reducing the vulnerability of individuals and communities to HIV and alleviating the impact of the epidemic. UNAIDS seeks to prevent the HIV/AIDS epidemic from becoming a severe pandemic. UNAIDS is headquartered in Geneva, Switzerland, where it shares some site facilities with the World Health Organization. It is a member of the United Nations Development Group. Currently, Winnie Byanyima leads UNAIDS as executive director. Former executive directors are Peter Piot (1995–2008) and Michel Sidibé (2009–2019). The agency promotes the GIPA principle (greater involvement of people living with HI ...
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Cost-effectiveness Analysis
Cost-effectiveness analysis (CEA) is a form of economic analysis that compares the relative costs and outcomes (effects) of different courses of action. Cost-effectiveness analysis is distinct from cost–benefit analysis, which assigns a monetary value to the measure of effect. Cost-effectiveness analysis is often used in the field of health services, where it may be inappropriate to monetize health effect. Typically the CEA is expressed in terms of a ratio where the denominator is a gain in health from a measure (years of life, premature births averted, sight-years gained) and the numerator is the cost associated with the health gain. The most commonly used outcome measure is quality-adjusted life years (QALY). Cost–utility analysis is similar to cost-effectiveness analysis. Cost-effectiveness analyses are often visualized on a plane consisting of four quadrants, the cost represented on one axis and the effectiveness on the other axis. Cost-effectiveness analysis focuses on m ...
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Bioethics
Bioethics is both a field of study and professional practice, interested in ethical issues related to health (primarily focused on the human, but also increasingly includes animal ethics), including those emerging from advances in biology, medicine and technologies. It proposes the discussion about moral discernment in society (what decisions are "good" or "bad" and why) and it is often related to medical policy and practice, but also to broader questions as environment, well-being and public health. Bioethics is concerned with the ethical questions that arise in the relationships among life sciences, biotechnology, medicine, politics, law, theology and philosophy. It includes the study of values relating to primary care, other branches of medicine ( "the ethics of the ordinary"), ethical education in science, animal, and environmental ethics, and public health. Etymology The term ''Bioethics'' (Greek , life; , behavior) was coined in 1927 by Fritz Jahr in an article about a "b ...
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Heterosexual Men
Heterosexuality is romantic attraction, sexual attraction or sexual behavior between people of the opposite sex or gender. As a sexual orientation, heterosexuality is "an enduring pattern of emotional, romantic, and/or sexual attractions" to people of the opposite sex; it "also refers to a person's sense of identity based on those attractions, related behaviors, and membership in a community of others who share those attractions." Someone who is heterosexual is commonly referred to as ''straight.'' Along with bisexuality and homosexuality, heterosexuality is one of the three main categories of sexual orientation within the heterosexual–homosexual continuum. Across cultures, most people are heterosexual, and heterosexual activity is by far the most common type of sexual activity. Scientists do not know the exact cause of sexual orientation, but they theorize that it is caused by a complex interplay of genetic, hormonal, and environmental influences, and do not view it as ...
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