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CaBIG
The cancer Biomedical Informatics Grid (caBIG) was a US government program to develop an open-source, open access information network called caGrid for secure data exchange on cancer research. The initiative was developed by the National Cancer Institute (part of the National Institutes of Health) and was maintained by the Center for Biomedical Informatics and Information Technology (CBIIT). In 2011 a report on caBIG raised significant questions about effectiveness and oversight, and its budget and scope were significantly trimmed. In May 2012, the National Cancer Informatics Program (NCIP) was created as caBIG's successor program. History The National Cancer Institute (NCI) of the United States funded the cancer Biomedical Informatics Grid (caBIG) initiative in spring 2004, headed by Kenneth Buetow. Its goal was to connect US biomedical cancer researchers using technology known as grid computing. The program, led by the Center for Bioinformatics and Information Technology (CBI ...
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National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship. NCI is the oldest and has the largest budget and research program of the 27 institutes and centers of the NIH ($6.9 billion in 2020). It fulfills the majority of its mission via an extramural program that provides grants for cancer research. Additionally, the National Cancer Institute has intramural research programs in Bethesda, Maryland, and at the Frederick National Laboratory for Cancer Research at Fort Detrick in Frederick, Maryland. The NCI receives more than in funding each ...
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Breast Cancer
Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a lack of physical exercise, alcoholism, hormone replacement therapy during menopause, ionizing radiation, an early age at first menstruation, having children late in life or not at all, older age, having a prior history of breast cancer, and a family history of breast cancer. About 5–10% of cases are the result of a genetic predisposition inherited from a person's parents, including BRCA1 and BRCA2 among others. Breast cancer most commonly develops in cells from the lining of milk ducts and the lobules that supply these ...
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GlaxoSmithKline
GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the tenth largest pharmaceutical company and #294 on the 2022 ''Fortune'' Global 500, ranked behind other pharmaceutical companies China Resources, Sinopharm, Johnson & Johnson, Pfizer, Roche, AbbVie, Novartis, Bayer, and Merck. The company has a primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index. , it had a market capitalisation of £70 billion, the eighth largest on the London Stock Exchange. It has a secondary listing on the New York Stock Exchange. The company developed the first malaria vaccine, RTS,S, which it said in 2014 it would make available for five percent above cost. Legacy products developed at GSK include several listed in the World Health Organization's List of Essential Medicines, such ...
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Freedom Of Information Act (United States)
The Freedom of Information Act (FOIA), , is the U.S. federal freedom of information law that requires the full or partial disclosure of previously unreleased or uncirculated information and documents controlled by the United States government, state, or other public authority upon request. The act defines agency records subject to disclosure, outlines mandatory disclosure procedures, and includes nine exemptions that define categories of information not subject to disclosure. The act was intended to make U.S. government agencies' functions more transparent so that the American public could more easily identify problems in government functioning and put pressure on Congress, agency officials, and the president to address them. The FOIA has been changed repeatedly by both the legislative and executive branches. Apart from the U.S. federal government's Freedom of Information Act, the U.S. states have their own varying freedom of information laws. The Freedom of Information Act is c ...
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Open-source Software
Open-source software (OSS) is computer software that is released under a license in which the copyright holder grants users the rights to use, study, change, and distribute the software and its source code to anyone and for any purpose. Open-source software may be developed in a collaborative public manner. Open-source software is a prominent example of open collaboration, meaning any capable user is able to participate online in development, making the number of possible contributors indefinite. The ability to examine the code facilitates public trust in the software. Open-source software development can bring in diverse perspectives beyond those of a single company. A 2008 report by the Standish Group stated that adoption of open-source software models has resulted in savings of about $60 billion per year for consumers. Open source code can be used for studying and allows capable end users to adapt software to their personal needs in a similar way user scripts an ...
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Liferay
Liferay, Inc., is an open-source company that provides free documentation and paid professional service to users of its software. Mainly focused on enterprise portal technology, the company has its headquarters in Diamond Bar, California, United States. History Liferay's original product, Liferay Portal, was created in 2000 by chief software architect Brian Chan to provide an enterprise portal solution for non-profit organizations. In 2004, the company was incorporated under the name Liferay, Inc. and formalized its Germany subsidiary Liferay GmbH. In 2007, the company opened a new Asian headquarters in Dalian, China, and the Spanish subsidiary Liferay SL. In March 2009, the company opened a new office in Bangalore, India. To date Liferay has 22 offices worldwide with over 250 partners and 180,000 open source community members. Sun Microsystems and Liferay signed a technology-sharing agreement during May 2008. Sun Microsystems rebranded the offering GlassFish Web Space Serv ...
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Software Development Kit
A software development kit (SDK) is a collection of software development tools in one installable package. They facilitate the creation of applications by having a compiler, debugger and sometimes a software framework. They are normally specific to a hardware platform and operating system An operating system (OS) is system software that manages computer hardware, software resources, and provides common services for computer programs. Time-sharing operating systems schedule tasks for efficient use of the system and may also in ... combination. To create applications with advanced functionalities such as advertisements, push notifications, etc; most application software developers use specific software development kits. Some SDKs are required for developing a platform-specific app. For example, the development of an Android app on the Java (programming language), Java platform requires a Java Development Kit. For iOS applications (apps) the iOS SDK is required. For Universal ...
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Duke Cancer Institute
The Duke Cancer Institute (DCI) is a National Cancer Institute-designated Comprehensive Cancer Center, research facility, and hospital. The center is part of the Duke University School of Medicine and Duke University Health System located in Durham, North Carolina, United States. The center specializes in the treatment and prevention of cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ... and was ranked 41st in the '' U.S. News & World Report's'' 2021 list of top cancer hospitals. More than 10,000 new cancer patients are seen at Duke each year. In November 2010, Victor Dzau, MD, chancellor of health affairs for Duke University, formally unveiled the Duke Cancer Institute, during the topping out ceremony for the new building. The DCI is a single entity—the first of its kin ...
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Web Portal
A web portal is a specially designed website that brings information from diverse sources, like emails, online forums and search engines, together in a uniform way. Usually, each information source gets its dedicated area on the page for displaying information (a portlet); often, the user can configure which ones to display. Variants of portals include mashups and intranet "dashboards" for executives and managers. The extent to which content is displayed in a "uniform way" may depend on the intended user and the intended purpose, as well as the diversity of the content. Very often design emphasis is on a certain "metaphor" for configuring and customizing the presentation of the content (e.g., a dashboard or map) and the chosen implementation framework or code libraries. In addition, the role of the user in an organization may determine which content can be added to the portal or deleted from the portal configuration. A portal may use a search engine's application programming inte ...
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National Cancer Research Institute
The National Cancer Research Institute (NCRI) is a UK-wide partnership between cancer research funders, which promotes collaboration in cancer research. Its member organizations work together to maximize the value and benefit of cancer research for the benefit of patients and the public. Rather than replace or duplicate any of the functions of its members, it seeks to add value through joint planning, coordination and collaboration. History In May 1999, the UK Prime Minister held a Downing Street Cancer Summit which led to the formation of the Cancer Research Funders Forum, bringing together the main government and charitable agencies that fund cancer research in the UK for the first time. Ian Gibson MP, a former cancer researcher from the University of East Anglia, called for the creation of a UK National Cancer Institute in November 1998, modelled on the National Cancer Institute in the USA. He used his influence as a member of the British House of Commons Science and Technolog ...
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The Cancer Genome Atlas
''The'' () is a grammatical article in English, denoting persons or things already mentioned, under discussion, implied or otherwise presumed familiar to listeners, readers, or speakers. It is the definite article in English. ''The'' is the most frequently used word in the English language; studies and analyses of texts have found it to account for seven percent of all printed English-language words. It is derived from gendered articles in Old English which combined in Middle English and now has a single form used with pronouns of any gender. The word can be used with both singular and plural nouns, and with a noun that starts with any letter. This is different from many other languages, which have different forms of the definite article for different genders or numbers. Pronunciation In most dialects, "the" is pronounced as (with the voiced dental fricative followed by a schwa) when followed by a consonant sound, and as (homophone of pronoun ''thee'') when followed by a v ...
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Susan Love
Susan M. Love (born February 9, 1948) is an American surgeon, a prominent advocate of preventive breast cancer research, and author. She is regarded as one of the most respected women’s health specialists in the United States. In 2012 Love announced that she was diagnosed with leukemia and would take a leave of absence to pursue chemotherapy treatment. After a successful treatment, Love returned to work the following year. Early life and education Love was born in Little Silver, New Jersey and moved to Puerto Rico as a teenager. She enrolled at Fordham University after having spent five unsuccessful months as a nun with the School Sisters of Notre Dame.Gleick, Elizabeth"Susan Love; A Surgeon Crusades Against Breast Cancer" '' People (magazine)'', July 25, 1994. Accessed September 3, 2015. "Born in Little Silver, N.J., the oldest of five children of Peggy and James Love, she moved to Puerto Rico when she was 13 after her father, a salesman for the Eaton machinery company, was ...
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