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Chondrodysplastic
Dwarfism is a condition wherein an organism is exceptionally small, and mostly occurs in the animal kingdom. In humans, it is sometimes defined as an adult height of less than , regardless of sex; the average adult height among people with dwarfism is , although some individuals with dwarfism are slightly taller. ''Disproportionate dwarfism'' is characterized by either short limbs or a short torso. In cases of ''proportionate dwarfism'', both the limbs and torso are unusually small. Intelligence is usually normal, and most have a nearly normal life expectancy. People with dwarfism can usually bear children, though there are additional risks to the mother and child dependent upon the underlying condition. The most common and recognisable form of dwarfism in humans (comprising 70% of cases) is achondroplasia, a genetic disorder whereby the limbs are diminutive. Growth hormone deficiency is responsible for most other cases. Treatment depends on the underlying cause. Those w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbus, Indiana
Columbus is a city in and the county seat of Bartholomew County, Indiana, United States. The population was 50,474 at the 2020 census. The relatively small city has provided a unique place for noted Modern architecture and public art, commissioning numerous works since the mid-20th century; the annual program Exhibit Columbus celebrates this legacy. Located about south of Indianapolis, on the east fork of the White River, it is the state's 20th-largest city. It is the principal city of the Columbus, Indiana metropolitan statistical area, which encompasses all of Bartholomew County. Columbus is the birthplace of former Indiana Governor and former Vice President of the United States, Mike Pence. Columbus is the headquarters of the engine company Cummins, Inc. in 2004 the city was named as one of "The Ten Most Playful Towns" by ''Nick Jr. Family Magazine''. In the July 2005 edition of '' GQ'' magazine, Columbus was named as one of the "62 Reasons to Love Your Country". Columbus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hormone Disorders
Endocrine diseases are disorders of the endocrine system. The branch of medicine associated with endocrine disorders is known as endocrinology. Types of disease Broadly speaking, endocrine disorders may be subdivided into three groups: # Endocrine gland hypofunction/hypo secretion (leading to hormone deficiency) # Endocrine gland hyperfunction/hypersecretion (leading to hormone excess) # Tumours (benign or malignant) of endocrine glands Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of hyperthyroidism are associated with an excess of thyroid hormone and a low level of thyroid stimulating hormone. List of diseases Glucose homeostasis disorders * Diabetes ** Type 1 Diabetes ** Type 2 Diabetes ** Gestational Diabetes ** Mature Onset Diabetes of the Young * Hypoglycemia ** Idiopathic hypoglycemia ** Insulinoma * Glucagonoma T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ear Infection
Otitis is a general term for inflammation or infection, inner ear infection, middle ear infection of the ear, in both humans and other animals. When infection is present, it may be viral or bacterial. When inflammation is present due to fluid build up in the middle ear and infection is not present it is considereOtitis media with effusion It is subdivided into the following: * ''Otitis externa'', external otitis, or "swimmer's ear", involves the outer ear and ear canal. In external otitis, we see tenderness in the pinna—i.e., the outer ear hurts when touched or pulled. * ''Otitis media'', or middle ear infection, involves the middle ear. In otitis media, the ear is infected or clogged with fluid behind the ear drum, in the normally air-filled middle-ear space. This is the most common infection and very common in babies below 6 months. This condition sometimes requires a surgical procedure called ''myringotomy'' and tube insertion. * ''Otitis interna'', or labyrinthitis, involv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinal Stenosis
Spinal stenosis is an abnormal narrowing of the spinal canal or neural foramen that results in pressure on the spinal cord or nerve roots. Symptoms may include pain, numbness, or weakness in the arms or legs. Symptoms are typically gradual in onset and improve with leaning forward. Severe symptoms may include loss of bladder control, loss of bowel control, or sexual dysfunction. Causes may include osteoarthritis, rheumatoid arthritis, spinal tumors, trauma, Paget's disease of the bone, scoliosis, spondylolisthesis, and the genetic condition achondroplasia. It can be classified by the part of the spine affected into cervical, thoracic, and lumbar stenosis. Lumbar stenosis is the most common, followed by cervical stenosis. Diagnosis is generally based on symptoms and medical imaging. Treatment may involve medications, bracing, or surgery. Medications may include NSAIDs, acetaminophen, or steroid injections. Stretching and strengthening exercises may also be useful. Limiting ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypochondroplasia
Hypochondroplasia (HCH) is a developmental disorder caused by an autosomal dominant genetic defect in the fibroblast growth factor receptor 3 gene (''FGFR3'') that results in a disproportionately short stature, micromeliaupdate 2013 and a head that appears large in comparison with the underdeveloped portions of the body. It is classified as short-limbed dwarfism. Signs and symptoms Individuals affected by this disorder appear normal at birth. As the infant grows, however, their arms and legs do not develop properly, and their body becomes thicker and shorter than normal. The following are characteristics consistent with this condition: * Brachydactyly * Short stature * Micromelia * Skeletal dysplasia * Abnormality of femur Cause Hypochondroplasia is transmitted as an autosomal dominant trait affecting the ''FGFR3'' gene on chromosome 4p16.3. There is currently no cure for this condition. Pathophysiology This disorder results from mutations in the proximal tyrosine kinase domain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dysplasia
Dysplasia is any of various types of abnormal growth or development of cells (microscopic scale) or organs (macroscopic scale), and the abnormal histology or anatomical structure(s) resulting from such growth. Dysplasias on a mainly microscopic scale include epithelial dysplasia and fibrous dysplasia of bone. Dysplasias on a mainly macroscopic scale include hip dysplasia (human), hip dysplasia, myelodysplastic syndrome, and multicystic dysplastic kidney. In one of the modern histopathology, histopathological senses of the term, dysplasia is sometimes differentiated from other categories of tissue change including hyperplasia, metaplasia, and neoplasia, and dysplasias are thus generally not cancerous. An exception is that the myelodysplasias include a range of benign tumor, benign, precancerous condition, precancerous, and cancerous forms. Various other dysplasias tend to be precancerous. The word's meanings thus cover a spectrum of histopathological variations. Microscopic sca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Midget
Midget (from ''midge'', a tiny biting insect) is a term for a person of unusually short stature that is considered by some to be pejorative due to its etymology. While not a medical term like "dwarfism", a medical condition with a number of causes including achondroplasia, there is overlap, particularly in proportionate dwarfism. The word has a history of association with the performance arts as little people were often employed by acts in the circus, professional wrestling and vaudeville. The term may also refer to anything of much smaller than normal size, as a synonym for "miniature" or "mini", such as midget cell, midget crabapple, midget flowerpecker, midget submarine, MG Midget, Daihatsu Midget, and the Midget Mustang airplane; or to anything that regularly uses anything that is smaller than normal (other than a person), such as midget car racing and quarter midget racing. "Midget" may also reference a smaller version of play or participation, such as midget golf; or t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dwarfism
Dwarfism is a condition wherein an organism is exceptionally small, and mostly occurs in the animal kingdom. In humans, it is sometimes defined as an adult height of less than , regardless of sex; the average adult height among people with dwarfism is , although some individuals with dwarfism are slightly taller. ''Disproportionate dwarfism'' is characterized by either short limbs or a short torso. In cases of ''proportionate dwarfism'', both the limbs and torso are unusually small. Intelligence is usually normal, and most have a nearly normal life expectancy. People with dwarfism can usually bear children, though there are additional risks to the mother and child dependent upon the underlying condition. The most common and recognisable form of dwarfism in humans (comprising 70% of cases) is achondroplasia, a genetic disorder whereby the limbs are diminutive. Growth hormone deficiency is responsible for most other cases. Treatment depends on the underlying cause. Those w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
English-speaking Countries
The following is a list of English-speaking population by country, including information on both native speakers and second-language speakers. List * The European Union is a supranational union composed of 27 member states. The total English-speaking population of the European Union and the United Kingdom combined (2012) is 256,876,220 (out of a total population of 500,000,000, i.e. 51%) including 65,478,252 native speakers and 191,397,968 non-native speakers, and would be ranked 2nd if it were included. English native speakers amount to 13% of the whole population of the EU and the UK, while the percentage of people that speak English "well enough in order to be able to have a conversation", either as first (32%), second (11%) or third (3%) foreign language, was 38%. * When taken from this list and added together, the total number of English speakers in the world adds up to around 1,200,000,000. Likewise, the total number of native English speakers adds up to around 350,00 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Height Discrimination
Height discrimination (also known as heightism) is prejudice or discrimination against individuals based on height. In principle, it refers to the discriminatory treatment against individuals whose height is not within the normal acceptable range of height in a population. Various studies have shown it to be a cause of bullying, commonly manifested as unconscious microaggressions. Research indicates that the human brain uses height as one factor to measure social status and fitness. Studies have observed that infants as young as 10 months old unconsciously associate height with leadership potential, power, strength and intelligence. Both the cognitive and the unconscious heuristic association between height and the mentioned traits has also been found to be stronger when assessing men than women. Lexicology The term ''heightism'' was coined by sociologist Saul Feldman in a paper titled "The presentation of shortness in everyday life—height and heightism in American society: T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Discrimination
Discrimination is the act of making unjustified distinctions between people based on the groups, classes, or other categories to which they belong or are perceived to belong. People may be discriminated on the basis of race, gender, age, religion, disability, or sexual orientation, as well as other categories. Discrimination especially occurs when individuals or groups are unfairly treated in a way which is worse than other people are treated, on the basis of their actual or perceived membership in certain groups or social categories. It involves restricting members of one group from opportunities or privileges that are available to members of another group. Discriminatory traditions, policies, ideas, practices and laws exist in many countries and institutions in all parts of the world, including territories where discrimination is generally looked down upon. In some places, attempts such as quotas have been used to benefit those who are believed to be current or past victims ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
