Canalisation (genetics)
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Canalisation (genetics)
Canalisation is a measure of the ability of a population to produce the same phenotype regardless of variability of its environment or genotype. It is a form of robustness (evolution), evolutionary robustness. The term was coined in 1942 by C. H. Waddington to capture the fact that "developmental reactions, as they occur in organisms submitted to natural selection...are adjusted so as to bring about one definite end-result regardless of minor variations in conditions during the course of the reaction". He used this word rather than robustness to consider that biological systems are not robust in quite the same way as, for example, engineered systems. Biological robustness or canalisation comes about when developmental biology, developmental pathways are evolutionary developmental biology, shaped by evolution. Waddington introduced the concept of the epigenetic landscape, in which the state of an organism rolls "downhill" during development. In this metaphor, a canalised trait is ...
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