Arbutin
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Arbutin
Arbutin is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus ''Arctostaphylos'' among many other medicinal plants, primarily in the family Ericaceae. Applied topically, it inhibits tyrosinase and thus prevents the formation of melanin. Arbutin is therefore used as a skin-lightening agent. Very tiny amounts of arbutin are found in wheat, pear skins, and some other foods. It is also found in '' Viburnum opulus'' and '' Bergenia crassifolia''. Arbutin was also produced by an in vitro culture of '' Schisandra chinensis''. It can be prepared synthetically from the reaction of acetobromoglucose and hydroquinone in the presence of alkali. Folk medicine Bearberry, which contains arbutin, is a traditional treatment for urinary tract infections. Skin lightening agent Bearberry extract is used in skin lightening treatments designed for long term and regular use. An active agent in brands of skin lightening preparations, it is more expensive th ...
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Arctostaphylos Uva-ursi
''Arctostaphylos uva-ursi'' is a plant species of the genus ''Arctostaphylos'' widely distributed across circumboreal regions of the subarctic Northern Hemisphere. Kinnikinnick (First Nations for "smoking mixture") is a common name in Canada and the United States. Growing up to in height, the leaves are evergreen. The flowers are white to pink and the fruit is a red berry. One of several related species referred to as bearberry, its specific epithet ''uva-ursi'' means "grape of the bear" in Latin (), similar to the meaning of the generic epithet ''Arctostaphylos'' (Greek for "bear grapes"). Description ''Arctostaphylos uva-ursi'' is a small procumbent woody groundcover shrub growing to high. Wild stands of the species can be dense, with heights rarely taller than . Erect branching twigs emerge from long flexible prostrate stems, which are produced by single roots. The trailing stems will layer, sending out small roots periodically. The finely textured velvety branches are init ...
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Taxifolin
Taxifolin (5,7,3',4'-flavan-on-ol), also known as dihydroquercetin, belongs to the subclass flavanonols in the flavonoids, which in turn is a class of polyphenols. Stereocenters Taxifolin has two stereocenters on the C-ring, as opposed to quercetin which has none. For example, (+)-taxifolin has (2R,3R)-configuration, making it 1 out of 4 stereoisomers that comprise 2 pairs of enantiomers. Natural occurrences Taxifolin is found in non-glutinous rice boiled with adzuki bean (adzuki-meshi). It can be found in conifers like the Siberian larch, ''Larix sibirica'', in Russia, in ''Pinus roxburghii'', in ''Cedrus deodara'' and in the Chinese yew, ''Taxus chinensis var. mairei''. It is also found in the silymarin extract from the milk thistle seeds. Taxifolin is present in vinegars aged in cherry wood. Taxifolin, and flavonoids in general, can be found in many beverages and products. Specifically, taxifolin is found in plant-based foods like fruit, vegetables, wine, tea, and coco ...
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Bergenia Crassifolia
''Bergenia crassifolia'' is a species of flowering plant of the genus '' Bergenia'' in the family Saxifragaceae. Common names for the species include heart-leaved bergenia,Tomasz Aniśko. ''When Perennials Bloom: An Almanac for Planning and Planting.'' Timber Press, 2008. p. 121. heartleaf bergenia, leather bergenia, winter-blooming bergenia,Ruth Rogers Clausen and Thomas Christopher. ''Essential Perennials: The Complete Reference to 2700 Perennials for the Home Garden.'' Timber Press, 2015. . p. 88. elephant-ears, elephant's ears, Korean elephant-ear, badan, pigsqueak, Siberian tea, and Mongolian tea. The species epithet ''crassifolia'' means "thick-leaved", while the epithet in the synonym ''Bergenia cordifolia'' means "cordate (heart-shaped) leaf" (although the leaves may also be described as spoon-shaped). The cultivar 'Rosa Zeiten' has gained the Royal Horticultural Society's Award of Garden Merit. Description It grows to about tall. The leaves are winter hardy in warmer ...
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Glycoside
In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. Several species of '' Heliconius'' butterfly are capable of incorporating these plant compounds as a form of chemical defense against predators. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body. In formal terms, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Glycosides can be linked by an O- (an '' O-glycoside''), N- (a ''glycosylamine''), S-(a '' thioglycoside''), or C- (a ''C-glycoside'') glycosidic bond. According ...
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Glucoside
A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes. The name was originally given to plant products of this nature, in which the other part of the molecule was, in the greater number of cases, an aromatic aldehydic or phenolic compound (exceptions are Jinigrin and Jalapin or Scammonin). It has now been extended to include synthetic ethers, such as those obtained by acting on alcoholic glucose solutions with hydrochloric acid, and also the polysaccharoses, e.g. cane sugar, which appear to be ethers also. Although glucose is the most common sugar present in glucosides, many are known which yield rhamnose or iso-dulcite; these may be termed pentosides. Much attention has been given to the non-sugar parts (aglyca) of the molecules; the constitutions of many have been determined, and the compounds synt ...
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Bearberry
Bearberries ( indigenous kinnickinnick) are three species of dwarf shrubs in the genus '' Arctostaphylos''. Unlike the other species of ''Arctostaphylos'' (see manzanita), they are adapted to Arctic and Subarctic climates, and have a circumpolar distribution in northern North America, Asia and Europe. Description Bearberries grow as low-lying bushes and these shrubs are green coloured year round. Furthermore, one can see from the images that they have a round shape to them as well. They are capable of surviving on soils predominantly composed of sand. In Canada, they are found in the Northern Latitude forests, and they can also be found growing on gravel surfaces. Species The name "bearberry" for the plant derives from the edible fruit which is a favorite food of bears. The fruit are edible and are sometimes gathered as food for humans. The leaves of the plant are used in herbal medicine.Pegg, Ronald B.; Rybarczyk, Anna and Amarowicz, Ryszard (2008"Chromatographic Sep ...
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Ferulic Acid
Ferulic acid is a hydroxycinnamic acid, an organic compound with the formula (CH3O)HOC6H3CH=CHCO2H. The name is derived from the genus '' Ferula'', referring to the giant fennel (''Ferula communis''). Classified as a phenolic phytochemical, ferulic acid is an amber colored solid. Esters of ferulic acid are found in plant cell walls, covalently bonded to hemicellulose such as arabinoxylans. Occurrence in nature As a building block of lignocelluloses, such as pectin and lignin, ferulic acid is ubiquitous in the plant kingdom, including a number of vegetable sources. It occurs in particularly high concentrations in popcorn and bamboo shoots. It is a major metabolite of chlorogenic acids in humans along with caffeic and isoferulic acid, and is absorbed in the small intestine, whereas other metabolites such as dihydroferulic acid, feruloylglycine and dihydroferulic acid sulfate are produced from chlorogenic acid in the large intestine by the action of gut flora. In cerea ...
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Intestinal Cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the Colon (anatomy), colon or rectum (parts of the large intestine). Signs and symptoms may include Lower gastrointestinal bleeding, blood in the stool, a change in bowel movements, weight loss, and fatigue. Most colorectal cancers are due to old age and lifestyle factors, with only a small number of cases due to underlying genetic disorders. Risk factors include diet, obesity, smoking, and lack of physical activity. Dietary factors that increase the risk include red meat, processed meat, and alcohol. Another risk factor is inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis. Some of the inherited genetic disorders that can cause colorectal cancer include familial adenomatous polyposis and hereditary non-polyposis colon cancer; however, these represent less than 5% of cases. It typically starts as a adenoma, benign tumor, often in t ...
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Potsdam
Potsdam () is the capital and, with around 183,000 inhabitants, largest city of the German state of Brandenburg. It is part of the Berlin/Brandenburg Metropolitan Region. Potsdam sits on the River Havel, a tributary of the Elbe, downstream of Berlin, and lies embedded in a hilly morainic landscape dotted with many lakes, around 20 of which are located within Potsdam's city limits. It lies some southwest of Berlin's city centre. The name of the city and of many of its boroughs are of Slavic origin. Potsdam was a residence of the Prussian kings and the German Kaiser until 1918. Its planning embodied ideas of the Age of Enlightenment: through a careful balance of architecture and landscape, Potsdam was intended as "a picturesque, pastoral dream" which would remind its residents of their relationship with nature and reason. The city, which is over 1000 years old, is widely known for its palaces, its lakes, and its overall historical and cultural significance. Landmarks include ...
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Melanocytes
Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart. Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes present than lighter skin tones. Functionally, melanin serves as protection against UV radiation. Melanocytes also have a role in the immune system. Function Through a process called melanogenesis, melanocytes produce melanin, which is a pigment found in the skin, eyes, hair, nasal cavity, and inner ear. This melanogenesis leads to a long-lasting pigmentation, which is in contrast to the pigmentation that originates from oxidation of already-existing melanin. There are both ...
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Urinary Tract Infection
A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects the lower urinary tract it is known as a bladder infection (cystitis) and when it affects the upper urinary tract it is known as a kidney infection (pyelonephritis). Symptoms from a lower urinary tract infection include pain with urination, frequent urination, and feeling the need to urinate despite having an empty bladder. Symptoms of a kidney infection include fever and flank pain usually in addition to the symptoms of a lower UTI. Rarely the urine may appear bloody. In the very old and the very young, symptoms may be vague or non-specific. The most common cause of infection is ''Escherichia coli'', though other bacteria or fungi may sometimes be the cause. Risk factors include female anatomy, sexual intercourse, diabetes, obesity, and family history. Although sexual intercourse is a risk factor, UTIs are not classified as sexually transmitted infections (STIs). K ...
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