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Antivenin
Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended only if there is significant toxicity or a high risk of toxicity. The specific antivenom needed depends on the species involved. It is given by injection. Side effects may be severe. They include serum sickness, shortness of breath, and allergic reactions including anaphylaxis. Antivenom is traditionally made by collecting venom from the relevant animal and injecting small amounts of it into a domestic animal. The antibodies that form are then collected from the domestic animal's blood and purified. Versions are available for spider bites, snake bites, fish stings, and scorpion stings. Due to the high cost of producing antibody-based antivenoms and their short shelf lives when not refrigerated, alternative methods of production of antivenoms ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coral Snake
Coral snakes are a large group of elapid snakes that can be divided into two distinct groups, the Old World coral snakes and New World coral snakes. There are 16 species of Old World coral snakes, in three genera (''Calliophis'', '' Hemibungarus'', and ''Sinomicrurus''), and over 65 recognized species of New World coral snakes, in two genera (''Micruroides'' and ''Micrurus''). Genetic studies have found that the most basal lineages have origins in Asia, suggesting that the group originated in the Old World. While new world species of both genera are venomous, their bites are seldom lethal; only two confirmed fatalities have been documented in the past 100 years from the genus ''Micrurus''. Meanwhile, snakes of the genus ''Micruroides'' have never caused a medically-significant bite. North American coloration patterns Experts now recognize that certain coloration patterns and common mnemonics - such as the phrase “Red touch yellow, kill a fellow; red touch black, you’re good, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CroFab
Crotalidae polyvalent immune fab, sold under the brandname CroFab, is a snake antivenin, indicated for minimal or moderate North American Crotalid ( Rattlesnake, Copperhead and Cottonmouth/Water moccasin) snake envenomation. CroFab is composed of several monovalent Fragment antigen-binding proteins (Fab) derived from the blood of sheep immunized with one of four snake venom: ''Crotalus atrox'' (western diamondback rattlesnake), ''Crotalus adamanteus'' (Eastern diamondback rattlesnake), ''Crotalus scutulatus'' (Mojave rattlesnake), or '' Agkistrodon piscivorus'' (Cottonmouth or Water Moccasin). Each monospecific antivenin is purified from sheep serum, digested with the enzyme papain, and purified further resulting in specific Fab fragments. The resulting four different Fab preparations are mixed to formulate the final product. Background It was developed by the Venom Immunochemistry, Pharmacology and Emergency Response (VIPER) Institute, University of Arizona, and commercial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Snake Antivenom
Snake antivenom is a medication made up of antibodies used to treat snake bites by venomous snakes. It is a type of antivenom. It is a biological product that typically consists of venom neutralizing antibodies derived from a host animal, such as a horse or sheep. The host animal is hyperimmunized to one or more snake venoms, a process which creates an immunological response that produces large numbers of neutralizing antibodies against various components (toxins) of the venom. The antibodies are then collected from the host animal, and further processed into snake antivenom for the treatment of envenomation. It is on the World Health Organization's List of Essential Medicines. Production Antivenoms are typically produced using a donor animal, such as a horse or sheep. The donor animal is hyperimmunized with non-lethal doses of one or more venoms to produce a neutralizing antibody response. Then, at certain intervals, the blood from the donor animal is collected and neutraliz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spider Bites
A spider bite, also known as arachnidism, is an injury resulting from the bite of a spider. The effects of most bites are not serious. Most bites result in mild symptoms around the area of the bite. Rarely they may produce a necrotic skin wound or severe pain. Most spiders do not cause bites that are of importance. For a bite to be significant, substantial envenomation is required. Bites from the widow spiders involve a neurotoxic venom which produces a condition known as latrodectism. Symptoms may include pain which may be at the bite or involve the chest and abdomen, sweating, muscle cramps and vomiting among others. Bites from the recluse spiders cause the condition loxoscelism, in which local necrosis of the surrounding skin and widespread breakdown of red blood cells may occur. Headaches, vomiting and a mild fever may also occur. Other spiders that can cause significant bites include the Australian funnel-web spider and South American wandering spider. Efforts to prev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rattlesnake
Rattlesnakes are venomous snakes that form the genera ''Crotalus'' and ''Sistrurus'' of the subfamily Crotalinae (the pit vipers). All rattlesnakes are vipers. Rattlesnakes are predators that live in a wide array of habitats, hunting small animals such as birds and rodents. Rattlesnakes receive their name from the rattle located at the end of their tails, which makes a loud rattling noise when vibrated that deters predators or serves as a warning to passers-by. Rattlesnakes are the leading contributor to snakebite injuries in North America, but rarely bite unless provoked or threatened; if treated promptly, the bites are seldom fatal. The 36 known species of rattlesnakes have between 65 and 70 subspecies, all native to the Americas, ranging from British Columbia through Ontario in southern Canada, to central Argentina. The largest rattlesnake, the eastern diamondback, can measure up to in length. Rattlesnakes are preyed upon by hawks, weasels, king snakes, and a variety ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Snake
Snakes are elongated, Limbless vertebrate, limbless, carnivore, carnivorous reptiles of the suborder Serpentes . Like all other Squamata, squamates, snakes are ectothermic, amniote vertebrates covered in overlapping Scale (zoology), scales. Many species of snakes have skulls with several more joints than their lizard ancestors, enabling them to swallow prey much larger than their heads (cranial kinesis). To accommodate their narrow bodies, snakes' paired organs (such as kidneys) appear one in front of the other instead of side by side, and most have only one functional lung. Some species retain a pelvic girdle with a pair of vestigial claws on either side of the cloaca. Lizards have evolved elongate bodies without limbs or with greatly reduced limbs about twenty-five times independently via convergent evolution, leading to many lineages of legless lizards. These resemble snakes, but several common groups of legless lizards have eyelids and external ears, which snakes lack, altho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anaphylaxis
Anaphylaxis is a serious, potentially fatal allergic reaction and medical emergency that is rapid in onset and requires immediate medical attention regardless of use of emergency medication on site. It typically causes more than one of the following: an itchy rash, throat closing due to swelling which can obstruct or stop breathing; severe tongue swelling which can also interfere with or stop breathing; shortness of breath, vomiting, lightheadedness, loss of consciousness, low blood pressure, and medical shock. These symptoms typically start in minutes to hours and then increase very rapidly to life-threatening levels. Urgent medical treatment is required to prevent serious harm or death, even if the patient has used an epipen or has taken other medications in response, and even if symptoms appear to be improving. Common causes include allergies to insect bites and stings, allergies to foods – including nuts, milk, fish, shellfish, eggs and some fresh fruits or dried fruits; a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science Daily
''Science Daily'' is an American website launched in 1995 that aggregates press releases and publishes lightly edited press releases (a practice called churnalism) about science, similar to Phys.org and EurekAlert!. The site was founded by married couple Dan and Michele Hogan in 1995; Dan Hogan formerly worked in the public affairs department of Jackson Laboratory writing press releases. The site makes money from selling advertisements. As of 2010, the site said that it had grown "from a two-person operation to a full-fledged news business with worldwide contributors". At the time, it was run out of the Hogans' home, had no reporters, and only reprinted press releases. In 2012, Quantcast Quantcast is an American technology company, founded in 2006, that specializes in AI-driven real-time advertising, audience insights and measurement. It has offices in the United States, Canada, Australia, Singapore, United Kingdom, Ireland, Fran ... ranked it at 614 with 2.6 million U.S. vi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward Jenner
Edward Jenner, (17 May 1749 – 26 January 1823) was a British physician and scientist who pioneered the concept of vaccines, and created the smallpox vaccine, the world's first vaccine. The terms ''vaccine'' and ''vaccination'' are derived from ''Variolae vaccinae'' ('pustules of the cow'), the term devised by Jenner to denote cowpox. He used it in 1798 in the title of his ''Inquiry into the Variolae vaccinae known as the Cow Pox'', in which he described the protective effect of cowpox against smallpox. In the West, Jenner is often called "the father of immunology", and his work is said to have saved "more lives than any other man". In Jenner's time, smallpox killed around 10% of global population, with the number as high as 20% in towns and cities where infection spread more easily. In 1821, he was appointed physician to King George IV of the United Kingdom, George IV, and was also made mayor of Berkeley, Gloucestershire, Berkeley and justice of the peace. A member of the Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vaccine
A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or Antigen, killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic vaccines, therapeutic (to fight a disease that has already occurred, such as cancer vaccine, cancer). [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Freeze Drying
Freeze drying, also known as lyophilization or cryodesiccation, is a low temperature dehydration process that involves freezing the product and lowering pressure, removing the ice by sublimation. This is in contrast to dehydration by most conventional methods that evaporate water using heat. Because of the low temperature used in processing, the rehydrated product retains much of its original qualities. When solid objects like strawberries are freeze dried the original shape of the product is maintained. If the product to be dried is a liquid, as often seen in pharmaceutical applications, the properties of the final product are optimized by the combination of excipients (i.e., inactive ingredients). Primary applications of freeze drying include biological (e.g., bacteria and yeasts), biomedical (e.g., surgical transplants), food processing (e.g., coffee) and preservation. History The Inca were freeze drying potatoes into chuño from the 13th century. The process involved mult ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indian Journal Of Critical Care Medicine
The ''Indian Journal of Critical Care Medicine'' is a peer-reviewed open-access medical journal published on behalf of the Indian Society of Critical Care Medicine. The journal publishes articles on the subject of critical and intensive care including emergency medicine. Abstracting and indexing The journal is indexed with Abstracts on Hygiene and Communicable Diseases, Bioline International, CAB Abstracts, Caspur, CINAHL, DOAJ, EBSCO, EMCARE, Excerpta Medica/ EMBASE, Expanded Academic ASAP, JournalSeek, Global Health, Google Scholar, Health & Wellness Research Center, Health Reference Center Academic, HINARI, Index Copernicus, OpenJGate, PubMed, Scimago Journal Ranking, SCOLOAR, Scopus Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-l ..., SIIC databases, Tropical Diseases Bulletin, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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