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ZebraBox
The ZebraBox is an automated analysis chamber for the non-intrusive video observation of different types of freshwater marine indicator species, such as ''Dania rerio'' and ''Pimephales promelas''. It is a type of Larval Photomoter Response (LPR) assay, which is used to monitor the swimming behaviour of larvae. The ZebraBox contains a controlled enclosed system of 96-well plates containing a high-resolution camera fitted with an infrared light and a fixed-angle lens. The lighting conditions and illumination patterns can be manually controlled for fish acclimation and the simulation of circadian rhythms. The apparatus allows for the analysis of zebrafish locomotion and activity, thus it is used in the fields of drug discovery and toxicological Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Danio Rerio
The zebrafish (''Danio rerio'') is a freshwater fish belonging to the minnow family (Cyprinidae) of the order Cypriniformes. Native to South Asia, it is a popular aquarium fish, frequently sold under the trade name zebra danio (and thus often called a "tropical fish" although both tropical and subtropical). It is also found in private ponds. The zebrafish is an important and widely used vertebrate model organism in scientific research, for example in drug development, in particular pre-clinical development. It is also notable for its regenerative abilities, and has been modified by researchers to produce many transgenic strains. Taxonomy The zebrafish is a derived member of the genus '' Brachydanio'', of the family Cyprinidae. It has a sister-group relationship with ''Danio aesculapii''. Zebrafish are also closely related to the genus ''Devario'', as demonstrated by a phylogenetic tree of close species. Distribution Range The zebrafish is native to fresh water hab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Video
Video is an electronic medium for the recording, copying, playback, broadcasting, and display of moving visual media. Video was first developed for mechanical television systems, which were quickly replaced by cathode-ray tube (CRT) systems which, in turn, were replaced by flat panel displays of several types. Video systems vary in display resolution, aspect ratio, refresh rate, color capabilities and other qualities. Analog and digital variants exist and can be carried on a variety of media, including radio broadcast, magnetic tape, optical discs, computer files, and network streaming. History Analog video Video technology was first developed for mechanical television systems, which were quickly replaced by cathode-ray tube (CRT) television systems, but several new technologies for video display devices have since been invented. Video was originally exclusively a live technology. Charles Ginsburg led an Ampex research team developing one of the first practical vi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indicator Species
A bioindicator is any species (an indicator species) or group of species whose function, population, or status can reveal the qualitative status of the environment. The most common indicator species are animals. For example, copepods and other small water crustaceans that are present in many water body, water bodies can be monitored for changes (biochemical, physiological, or behavioural) that may indicate a problem within their ecosystem. Bioindicators can tell us about the cumulative effects of different pollution, pollutants in the ecosystem and about how long a problem may have been present, which Water pollution#Measurement, physical and chemical testing cannot. A biological monitor or biomonitor is an organism that provides quantitative property, quantitative information on the quality of Environment (biophysical), the environment around it. Therefore, a good biomonitor will indicate the presence of the pollutant and can also be used in an attempt to provide additional inform ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pimephales Promelas
Fathead minnow (''Pimephales promelas''), also known as fathead or tuffy, is a species of temperate freshwater fish belonging to the genus ''Pimephales'' of the cyprinid family. The natural geographic range extends throughout much of North America, from central Canada south along the Rockies to Texas, and east to Virginia and the Northeastern United States.Page, Lawrence M. and Brooks M. Burr (1991), ''Freshwater Fishes'', p. 129-130, Houghton Mifflin, New York, NY. This minnow has also been introduced to many other areas via bait bucket releases. Its golden, or xanthic, strain, known as the rosy-red minnow, is a very common feeder fish sold in the United States and Canada. This fish is best known for producing Schreckstoff (a distress signal). Physical description The fathead minnow in its wild form is generally dull olive-grey in appearance, with a dusky stripe extending along the back and side, and a lighter belly. There is a dusky blotch midway on the dorsal fin. Breedi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxicology
Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology is currently contributing to the field of cancer research, since some toxins can be used as drugs for killing tumor cells. One prime example of this is ribosome-inactivating proteins, tested in the treatment of leukemia. The word ''toxicology'' () is a neocla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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