The ZebraBox is an automated analysis chamber for the non-intrusive
video
Video is an electronic medium for the recording, copying, playback, broadcasting, and display of moving visual media. Video was first developed for mechanical television systems, which were quickly replaced by cathode-ray tube (CRT) syste ...
observation of different types of freshwater marine
indicator species
A bioindicator is any species (an indicator species) or group of species whose function, population, or status can reveal the qualitative status of the environment. The most common indicator species are animals. For example, copepods and other sma ...
, such as
''Dania rerio'' and ''
Pimephales promelas
Fathead minnow (''Pimephales promelas''), also known as fathead or tuffy, is a species of temperate freshwater fish belonging to the genus ''Pimephales'' of the cyprinid family. The natural geographic range extends throughout much of North Amer ...
''. It is a type of Larval Photomoter Response (LPR) assay, which is used to monitor the swimming behaviour of larvae.
The ZebraBox contains a controlled enclosed system of 96-well plates containing a high-resolution camera fitted with an infrared light and a fixed-angle lens. The lighting conditions and illumination patterns can be manually controlled for fish acclimation and the simulation of circadian rhythms. The apparatus allows for the analysis of zebrafish locomotion and activity, thus it is used in the fields of drug discovery and
toxicological
Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating expos ...
studies.
References
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External links
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ViewPoint Life Sciences Animal testing