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Zosteriform Speckled Lentiginous Nevus
Zosteriform speckled lentiginous nevus is a skin lesion that may be the result of a potentially lethal mutation. The terminology has been described as "confusing". It was characterized in 1981. Cutaneous findings in FACES syndrome include zosteriform speckled lentiginous nevi. See also * McCune–Albright syndrome * List of cutaneous conditions * Nevus spilus Nevus spilus, also known as speckled lentiginous nevus, is a light brown or tan birth mark, speckled with small, dark spots or small bumps. If it occurs in a segmental pattern then it is sometimes referred to as a Zosteriform speckled lentiginous ... References Epidermal nevi, neoplasms, and cysts {{Epidermal-growth-stub ...
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FACES Syndrome
FACES syndrome is a syndrome of unique facial features ( facies), a norexia, c achexia, eye and skin anomalies. It is a rare disease and estimated to occur in less than 1 in 1 million people. References External links Syndromes affecting the eye Musculoskeletal disorders Rare syndromes Syndromes affecting the skin Syndromes with craniofacial abnormalities {{Genetic-disorder-stub} ...
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McCune–Albright Syndrome
McCune–Albright syndrome is a complex genetic disorder affecting the bone, skin and endocrine systems. It is a mosaic disease arising from somatic activating mutations in '' GNAS'', which encodes the alpha-subunit of the Gs heterotrimeric G protein. It was first described in 1937 by American pediatrician Donovan James McCune and American endocrinologist Fuller Albright. Signs and symptoms McCune–Albright syndrome is suspected when two or more of the following features are present: * Fibrous dysplasia * Hyperpigmented skin lesions with characteristic features, including jagged "coast of Maine" borders and tendency occur along the midline of the body. These lesions are historically termed café au lait macules, however the term "cafe-au-lait" only describes their appearance on lighter-skinned individuals. * Hyperfunctioning endocrine disease Patients may have one or many of these features, which may occur in any combination. As such, the clinical presentation of patients w ...
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List Of Cutaneous Conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.Burns, Tony; ''et al''. (2006) ''Rook's Textbook of Dermatology CD-ROM''. Wiley-Blackwell. . Within the latter type, the hairs occur in structures called pilosebaceous units, each with hair follicle, sebaceous gland, and associated arrector pili muscle. In the embryo, the epidermis, hair, and glands form from the ectoderm, which is chemically influenced by the underlying mesoderm th ...
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Nevus Spilus
Nevus spilus, also known as speckled lentiginous nevus, is a light brown or tan birth mark, speckled with small, dark spots or small bumps. If it occurs in a segmental pattern then it is sometimes referred to as a Zosteriform speckled lentiginous nevus. It may be associated with types of phakomatosis pigmentovascularis. Prevalence is between 0.2% and 2.8%. See also * Phakomatosis pigmentokeratotica * Skin lesion A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of th ... * List of cutaneous conditions References External links Melanocytic nevi and neoplasms {{Cutaneous-condition-stub ...
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