|
Zenker's Degeneration
Zenker's degeneration is a severe glassy or waxy hyaline degeneration or necrosis of skeletal muscles in acute infectious diseases; a prototype of coagulative necrosis. The condition was named by Friedrich Albert von Zenker. It is a hyaline degeneration of skeletal muscles such as rectus abdominis and diaphragm Diaphragm may refer to: Anatomy * Thoracic diaphragm, a thin sheet of muscle between the thorax and the abdomen * Pelvic diaphragm or pelvic floor, a pelvic structure * Urogenital diaphragm or triangular ligament, a pelvic structure Other * Diap ..., and occurs in severe toxaemia as typhoid fever. It is also seen in electrical burns. Grossly the muscles appear pale and friable; microscopically, the muscle fibres are swollen, have a loss of cross striations, and show a hyaline appearance. Rupture and small hemorrhage may complicate the lesion. Coagulative necrosis occurs here. References Muscular disorders {{muscle-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyaline
A hyaline substance is one with a glassy appearance. The word is derived from el, ὑάλινος, translit=hyálinos, lit=transparent, and el, ὕαλος, translit=hýalos, lit=crystal, glass, label=none. Histopathology Hyaline cartilage is named after its glassy appearance on fresh gross pathology. On light microscopy of H&E stained slides, the extracellular matrix of hyaline cartilage looks homogeneously pink, and the term "hyaline" is used to describe similarly homogeneously pink material besides the cartilage. Hyaline material is usually acellular and proteinaceous. For example, arterial hyaline is seen in aging, high blood pressure, diabetes mellitus and in association with some drugs (e.g. calcineurin inhibitors). It is bright pink with PAS staining. Ichthyology and entomology In ichthyology and entomology, ''hyaline'' denotes a colorless, transparent substance, such as unpigmented fins of fishes or clear insect wings. Resh, Vincent H. and R. T. Cardé, Eds. Encyclo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Degeneration (medical)
Degeneration is deterioration in the medical sense. Generally, it is the change from a higher to a lower form. More specifically, it is the change of tissue to a lower or less functionally active form. *True degeneration: when there is actual chemical change of the tissue itself. *Infiltration: when the change consists of the deposit of abnormal matter in the tissues *Degenerative disease See also *macular degeneration *neurodegenerative disease A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic ... References Dorland's Illustrated Medical Dictionary (Twenty-sixth Edition) () Medical terminology {{med-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Necrosis
Necrosis () is a form of cell injury which results in the premature death of cells in living tissue by autolysis. Necrosis is caused by factors external to the cell or tissue, such as infection, or trauma which result in the unregulated digestion of cell components. In contrast, apoptosis is a naturally occurring programmed and targeted cause of cellular death. While apoptosis often provides beneficial effects to the organism, necrosis is almost always detrimental and can be fatal. Cellular death due to necrosis does not follow the apoptotic signal transduction pathway, but rather various receptors are activated and result in the loss of cell membrane integrity and an uncontrolled release of products of cell death into the extracellular space. This initiates in the surrounding tissue an inflammatory response, which attracts leukocytes and nearby phagocytes which eliminate the dead cells by phagocytosis. However, microbial damaging substances released by leukocytes would crea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skeleton
A skeleton is the structural frame that supports the body of an animal. There are several types of skeletons, including the exoskeleton, which is the stable outer shell of an organism, the endoskeleton, which forms the support structure inside the body, and the hydroskeleton, a flexible internal skeleton supported by fluid pressure. Vertebrates are animals with a vertebral column, and their skeletons are typically composed of bone and cartilage. Invertebrates are animals that lack a vertebral column. The skeletons of invertebrates vary, including hard exoskeleton shells, plated endoskeletons, or Sponge spicule, spicules. Cartilage is a rigid connective tissue that is found in the skeletal systems of vertebrates and invertebrates. Etymology The term ''skeleton'' comes . ''Sceleton'' is an archaic form of the word. Classification Skeletons can be defined by several attributes. Solid skeletons consist of hard substances, such as bone, cartilage, or cuticle. These can be further ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friedrich Albert Von Zenker
Friedrich Albert von Zenker (13 March 1825 – 13 June 1898) was a German pathologist and physician, celebrated for his discovery of trichinosis. He was born in Dresden, and was educated in Leipzig and Heidelberg. While in Leipzig, he worked for a while as an assistant to Justus Radius at the St. Georg Hospital. Attached to the city hospital of Dresden in 1851, he added, in 1855, the duties of professor of pathological anatomy and general pathology in the surgico-medical academy of that city. In 1862 he became professor of pathological anatomy and pharmacology at Erlangen. Three years afterwards he assumed with Hugo Wilhelm von Ziemssen the editorship of the "''Deutsches Archiv für klinische Medizin''". In 1895 he retired from active service. Zenker's diverticulum, a false pathological diverticulum of the posterior pharyngeal wall, through the thyropharyngeus and cricopharyngeus parts of the inferior constrictor muscle, is named after him. His important discovery of the dan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rectus Abdominis
The rectus abdominis muscle, ( la, straight abdominal) also known as the "abdominal muscle" or simply the "abs", is a paired straight muscle. It is a paired muscle, separated by a midline band of connective tissue called the linea alba. It extends from the pubic symphysis, pubic crest and pubic tubercle inferiorly, to the xiphoid process and costal cartilages of ribs V to VII superiorly. The proximal attachments are the pubic crest and the pubic symphysis. It attaches distally at the costal cartilages of ribs 5-7 and the xiphoid process of the sternum. The rectus abdominis muscle is contained in the rectus sheath, which consists of the aponeuroses of the lateral abdominal muscles. The outer, most lateral line, defining the rectus is the linea semilunaris. Bands of connective tissue traverse the rectus abdominis, separating it into distinct muscle bellies. In the abdomens of people with low body fat, these muscle bellies can be viewed externally. They can appear in sets of as f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thoracic Diaphragm
The thoracic diaphragm, or simply the diaphragm ( grc, διάφραγμα, diáphragma, partition), is a sheet of internal Skeletal striated muscle, skeletal muscle in humans and other mammals that extends across the bottom of the thoracic cavity. The diaphragm is the most important Muscles of respiration, muscle of respiration, and separates the thoracic cavity, containing the heart and lungs, from the abdominal cavity: as the diaphragm contracts, the volume of the thoracic cavity increases, creating a negative pressure there, which draws air into the lungs. Its high oxygen consumption is noted by the many mitochondria and capillaries present; more than in any other skeletal muscle. The term ''diaphragm'' in anatomy, created by Gerard of Cremona, can refer to other flat structures such as the urogenital diaphragm or Pelvic floor, pelvic diaphragm, but "the diaphragm" generally refers to the thoracic diaphragm. In humans, the diaphragm is slightly asymmetric—its right half is h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacteremia
Bloodstream infections (BSIs), which include bacteremias when the infections are bacterial and fungemias when the infections are fungal, are infections present in the blood. Blood is normally a sterile environment, so the detection of microbes in the blood (most commonly accomplished by blood cultures) is always abnormal. A bloodstream infection is different from sepsis, which is the host response to bacteria. Bacteria can enter the bloodstream as a severe complication of infections (like pneumonia or meningitis), during surgery (especially when involving mucous membranes such as the gastrointestinal tract), or due to catheters and other foreign bodies entering the arteries or veins (including during intravenous drug abuse). Transient bacteremia can result after dental procedures or brushing of teeth. Bacteremia can have several important health consequences. The immune response to the bacteria can cause sepsis and septic shock, which has a high mortality rate. Bacteria c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
