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Zanthoxylum Avicennae
''Zanthoxylum avicennae'' is a woody plant in the family Rutaceae. Description ''Z. avicennae'' is a deciduous tree that reaches 15 meters high. The trunk has chicken-foot-like thorns, the thorn base is oblate and thickened, shaped like a bulge, and displays ring patterns. The leaflets of the seedlings are very small, but as many as 31, on the branches of young trees. The leaves are densely thorny, and each part is glabrous. The leaves have 11-21 leaflets that are usually opposite or occasionally irregularly opposite, obliquely ovoid, obliquely rectangular or sickle-shaped, and are sometimes obovate. Seedling leaflets are mostly broad-ovate, 2.5-7 cm long, 1-3 cm wide, short pointed or blunt at the top, asymmetrical on both sides. It has sparsely cracked teeth on the whole or above the middle. The oil spots on fresh leaves are visible, while some are not obvious on the ventral surface of the leaf shaft. The leaf edges are narrow and green, and often narrow wing-shaped. The inflo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rutaceae
The Rutaceae is a family, commonly known as the rueRUTACEAE in BoDD – Botanical Dermatology Database or family, of s, usually placed in the order . Species of the family generally have s that divide into four or five parts, usually w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Avicine
Avicine, tested and developed by AVI BioPharma, and also known as CTP-37 was trialled as a possible cancer vaccine to treat a number of different cancers. These included colorectal cancer, pancreatic cancer and prostate cancer. The treatment was trialled as and intended to be induced via intramuscular injection into the bloodstream, the location dependent on the treatment area. Common side effects during clinical trials included fever and chills as experienced with many other conventional vaccines. The vaccine operated by eliciting antibodies against human chorionic gonadotropin (hCG) a cancer associated protein expressed by most cancer cells, with the goal of prolonged survival for those affected. Avicine was originated by AVI BioPharma in the USA, who licensed the product to SuperGen. However, due to delays in clinical testing, as a result of research difficulties, the owners of Avicine were forced to direct their attention to other areas being the investigation and treatment ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hesperidin
Hesperidin is a flavanone glycoside found in citrus fruits. Its aglycone form is called hesperetin. Its name is derived from the word "hesperidium", for fruit produced by citrus trees. Hesperidin was first isolated in 1828 by French chemist M. Lebreton from the white inner layer of citrus peels (mesocarp, albedo). Hesperidin is believed to play a role in plant defense. Sources ''Rutaceae'' * 700–2,500 ppm in fruit of ''Citrus aurantium'' (bitter orange, petitgrain) * in orange juice (''Citrus sinensis'') * in ''Zanthoxylum gilletii'' * in lemon * in lime * in leaves of ''Agathosma serratifolia'' ''Lamiaceae'' Peppermint contains hesperidin. Content in foods Approximate hesperidin content per 100 ml * 481 mg peppermint, dried * 44 mg blood orange, pure juice * 26 mg orange, pure juice * 18 mg lemon, pure juice * 14 mg lime, pure juice * 1 mg grapefruit, pure juice Metabolism Hesperidin 6-''O''-α--rhamnosyl-β--glucosidase, an enzyme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diosmin
Diosmin (diosmetin 7-O-rutinoside), a flavone glycoside of diosmetin, is manufactured from citrus fruit peels as a phlebotonic non-prescription dietary supplement used to aid treatment of hemorrhoids or chronic venous diseases, mainly of the legs. Uses Diosmin is a dietary supplement used to aid treatment of hemorrhoids and venous diseases, i.e., chronic venous insufficiency including spider and varicose veins, leg swelling (edema), stasis dermatitis and venous ulcers. The mechanism of action of Diosmin and other phlebotonics is undefined, and clinical evidence of benefit is limited. Diosmin is not recommended for treating the rectal mucosa, skin irritations, or wounds, and should not be used to treat dermatitis, eczema, or urticaria. Diosmin is not recommended for use in children or women during pregnancy. There is moderate-quality evidence that diosmin or other phlebotonics improved leg and ankle swelling and lower leg pain, and low-quality evidence for treating hemorrhoids ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coumarin
Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered heterocycle that shares two carbons with the benzene ring. It can be placed in the benzopyrone chemical class and considered as a lactone. Coumarin is a colorless crystalline solid with a sweet odor resembling the scent of vanilla and a bitter taste. It is found in many plants, where it may serve as a chemical defense against predators. By inhibiting synthesis of vitamin K, a related compound is used as the prescription drug warfarin – an anticoagulant – to inhibit formation of blood clots, deep vein thrombosis, and pulmonary embolism. Etymology Coumarin is derived from ''coumarou'', the French word for the tonka bean. The word ''tonka'' for the tonka bean is taken from the Galibi (Carib) tongue spoken by natives of French G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Candicine
Candicine is a naturally occurring organic compound that is a quaternary ammonium salt with a phenethylamine skeleton. It is the N,N,N-trimethyl derivative of the well-known biogenic amine tyramine, and, being a natural product with a positively charged nitrogen atom in its molecular structure, it is classed as an alkaloid. Although it is found in a variety of plants, including barley, its properties have not been extensively studied with modern techniques. Candicine is toxic after parenteral administration, producing symptoms of neuromuscular blocking drug, neuromuscular blockade; further details are given in the "Pharmacology" section below. Occurrence Candicine occurs in a variety of plants, notably the cacti. This alkaloid was first isolated from the Argentinian cactus ''Trichocereus candicans'' (now reclassified as ''Echinopsis candicans''), from which it derives its name, and from other ''Trichocereus'' species. ''T. candicans'' may contain up to 5% candicine, and is also a r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chelerythrine
Chelerythrine is a benzophenanthridine alkaloid present in the plant ''Chelidonium majus'' (greater celandine). It is a potent, selective, and cell-permeable protein kinase C inhibitor ''in vitro''. And an efficacious antagonist of G-protein-coupled CB1 receptors. This molecule also exhibits anticancer qualities and it has served as a base for many potential novel drugs against cancer. Structurally, this molecule has two distinct conformations, one being a positively charged iminium form, and the other being an uncharged form, a pseudo-base. It is also found in the plants ''Zanthoxylum clava-herculis'' and '' Zanthoxylum rhoifolium'', exhibiting antibacterial activity against ''Staphylococcus aureus'' and other human pathogens. Research Antibacterial agent Chelerythrine is a potent antibacterial agent that has aided in dealing with the emergence of antibacterial resistant bacteria. This molecule has the ability to disrupt a bacteria's cell wall and cell membrane, as well a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nitidine
Nitidine is a benzophenanthridine alkaloid found in species of the genus ''Zanthoxylum '', notably in ''Zanthoxylum nitidum ''Zanthoxylum nitidum'', commonly known as shiny-leaf prickly-ash, tez-mui (in Assamese) or liang mian zhen (in China), is a species of flowering plant in the family Rutaceae. It is a woody climber with prickles on the branchlets, thick, cone- ...''. This compound has an anti-malarial activity.Bouquet, J., et al. (2012)Biological activities of nitidine, a potential anti-malarial lead compound.''Malaria Journal'' 11:67 References Isoquinoline alkaloids Benzodioxoles Quinoline alkaloids Alkaloids found in Rutaceae Antimalarial agents {{alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloids
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids xumuk.ru Alkaloids are produced by a large variety of organisms including , , |
Glabrousness (botany)
Glabrousness (from the Latin ''glaber'' meaning "bald", "hairless", "shaved", "smooth") is the technical term for a lack of hair, down, setae, trichomes or other such covering. A glabrous surface may be a natural characteristic of all or part of a plant or animal, or be due to loss because of a physical condition, such as alopecia universalis in humans, which causes hair to fall out or not regrow. In botany Glabrousness or otherwise, of leaves, stems, and fruit is a feature commonly mentioned in plant keys; in botany and mycology, a ''glabrous'' morphological feature is one that is smooth and may be glossy. It has no bristles or hair-like structures such as trichomes. In anything like the zoological sense, no plants or fungi have hair or wool, although some structures may resemble such materials. The term "glabrous" strictly applies only to features that lack trichomes at all times. When an organ bears trichomes at first, but loses them with age, the term used is ''glabrescen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alpha-Pinene
α-Pinene is an organic compound of the terpene class, one of two isomers of pinene. It is an alkene and it contains a reactive four-membered ring. It is found in the oils of many species of many coniferous trees, notably the pine. It is also found in the essential oil of rosemary (''Rosmarinus officinalis'') and '' Satureja myrtifolia'' (also known as ''Zoufa'' in some regions). Both enantiomers are known in nature; (1''S'',5''S'')- or (−)-α-pinene is more common in European pines, whereas the (1''R'',5''R'')- or (+)-α-isomer is more common in North America. The racemic mixture is present in some oils such as eucalyptus oil and orange peel oil. Reactivity : Commercially important derivatives of alpha-pinene are linalool, geraniol, nerol, a-terpineol, and camphene. α-Pinene 1 is reactive owing to the presence of the four-membered ring adjacent to the alkene. The compound is prone to skeletal rearrangements such as the Wagner–Meerwein rearrangement. Acids typ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terpinene
The terpinenes are a group of isomeric hydrocarbons that are classified as monoterpenes. They each have the same molecular formula and carbon framework, but they differ in the position of carbon-carbon double bonds. α-Terpinene has been isolated from cardamom and marjoram oils, and from other natural sources. β-Terpinene has no known natural source but has been prepared from sabinene. γ-Terpinene and δ-terpinene (also known as terpinolene) have been isolated from a variety of plant sources. They are all colorless liquids with a turpentine-like odor. Production and uses α-Terpinene is produced industrially by acid-catalyzed rearrangement of α-pinene. It has perfume and flavoring properties but is mainly used to confer pleasant odor to industrial fluids. Hydrogenation gives the saturated derivative ''p''-menthane. Biosynthesis of α-terpinene The biosynthesis of α-terpinene and other terpenoids starts with the isomerization of geranyl pyrophosphate to linalyl pyroph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
