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Zambon
Zambon is an Italian company that has been operating in the pharmaceutical and fine chemical industry since 1906. The company is currently run by Elena Zambon who is the daughter of the founder.{{Cite news, url=http://www.repubblica.it/economia/affari-e-finanza/2017/07/03/news/credito_e_industria_il_nord-est_volta_pagina_i_nuovi_signori_della_locomotiva_italiana-169825826/?refresh_ce, title=Credito e industria, il Nord-Est volta pagina: i nuovi signori della locomotiva italiana, date=2017-07-03, work=Repubblica.it, access-date=2018-08-08, language=it Headquartered in Bresso, in the Province of Milan, the company has business operations in three continents: Europe, South America and Asia. The company employs approximately 2,600 people in 15 countries and its integrated organisation consists of Zambon Company SpA, the industrial holding company for the group which comprises Zach System (fine chemicals), Zambon SpA (pharmaceuticals) and Z-Cube (Research Venture). History Origins G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Safinamide
Safinamide (INN; brand name Xadago) is a drug used as an add-on treatment for Parkinson's disease with "off" episodes; it has multiple modes of action, including the inhibition of monoamine oxidase B. SeFDA index page for NDA 207145for updates. It was approved in the European Union in February 2015, in the United States in March 2017, and in Canada in January 2019. Medical uses Safinamide is used to treat idiopathic Parkinson's disease as add-on for people taking a stable dose of levodopa (L-dopa) alone or in combination with other Parkinson drugs, to help with "off" episodes when levodopa stops working. Contraindications Safinamide is contraindicated in people with severe liver impairment, with albinism, retinitis pigmentosa, severe diabetic neuropathy, uveitis and other disorders of the retina. Combination with other monoamine oxidase (MAO) inhibitors and pethidine is also contraindicated. It is not safe for women to take during pregnancy. It is excreted in breast milk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bresso
Bresso (Milanese: ) is a ''comune'' (municipality) in the Metropolitan City of Milan in the Italian region Lombardy, located about north of Milan. At the 2001 census the municipality had a population of 26,255 inhabitants and a population density of 8,027.2 persons/km², making it the most densely populated ''comune'' in Italy outside the Province of Naples. Bresso borders the following municipalities: Cinisello Balsamo, Cusano Milanino, Sesto San Giovanni, Cormano and Milan. Milan's general aviation General aviation (GA) is defined by the International Civil Aviation Organization (ICAO) as all civil aviation aircraft operations with the exception of commercial air transport or aerial work, which is defined as specialized aviation services ... airfield is located at Bresso and is the home of the Aero Club Milano and Aero Club Bresso. Transport Bresso Airport is in the commune. References External links Official website Cities and towns in Lombardy {{Mi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rhubarb
Rhubarb is the fleshy, edible stalks ( petioles) of species and hybrids (culinary rhubarb) of ''Rheum'' in the family Polygonaceae, which are cooked and used for food. The whole plant – a herbaceous perennial growing from short, thick rhizomes – is also called rhubarb. Historically, different plants have been called "rhubarb" in English. The large, triangular leaves contain high levels of oxalic acid and anthrone glycosides, making them inedible. The small flowers are grouped in large compound leafy greenish-white to rose-red inflorescences. The precise origin of culinary rhubarb is unknown. The species ''Rheum rhabarbarum'' (syn. ''R. undulatum'') and '' R. rhaponticum'' were grown in Europe before the 18th century and used for medicinal purposes. By the early 18th century, these two species and a possible hybrid of unknown origin, ''R.'' × ''hybridum'', were grown as vegetable crops in England and Scandinavia. They readily hybridize, and culinary rh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cystic Fibrosis
Cystic fibrosis (CF) is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms. Cystic fibrosis is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy are carriers and otherwise mostly healthy. CFTR is involved in the production of sweat, digestive fluids, and mucus. When the CFTR is not functional, secretions which are usually thin instead become thick. The condition is diagnosed by a sweat test and genetic testing. Screening of infants at bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by long-term respiratory symptoms and airflow limitation. The main symptoms include shortness of breath and a cough, which may or may not produce mucus. COPD progressively worsens, with everyday activities such as walking or dressing becoming difficult. While COPD is incurable, it is preventable and treatable. The two most common conditions of COPD are emphysema and chronic bronchitis and they have been the two classic COPD phenotypes. Emphysema is defined as enlarged airspaces ( alveoli) whose walls have broken down resulting in permanent damage to the lung tissue. Chronic bronchitis is defined as a productive cough that is present for at least three months each year for two years. Both of these conditions can exist without airflow limitation when they are not classed as COPD. Emphysema is just one of the structural abnormalities that can limit airflow and can exist without ai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Farmitalia
Farmitalia was an Italian pharmaceutical company best known for its parallel discovery with Rhone-Poulenc of daunorubicin and subsequent discovery of doxorubicin. Farmitalia had been founded in 1935 as a joint venture by Rhone-Poulenc and Montecatini. Farmitalia occupied a position of choice in the world rankings of the profession, not only in Italy, but also at the world level with in particular the patent of Adriamycin, an anti-cancer drug qualified. From its creation, Farmaceutici Italia buys the Schiapparelli factory. In 1978, Farmitalia was merged with Carlo Erba SpA, an Italian pharmaceutical company that had been founded in 1853 by the pharmacist , in which Montecatini had acquired a controlling interest in 1971. The merged company was called Farmitalia Carlo Erba SpA. Farmitalia Carlo Erba was acquired by Pharmacia in 1993, then Pharmacia was acquired by Pfizer in 2003. Drugs discovered at Farmitalia that reached the market included (with date of first publication): * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chloramphenicol
Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever. Its use by mouth or by injection is only recommended when safer antibiotics cannot be used. Monitoring both blood levels of the medication and blood cell levels every two days is recommended during treatment. Common side effects include bone marrow suppression, nausea, and diarrhea. The bone marrow suppression may result in death. To reduce the risk of side effects treatment duration should be as short as possible. People with liver or kidney problems may need lower doses. In young children a condition known as gray baby syndrome may occur which results in a swollen stomach and low blood pressure. Its use near the end of pregnancy and during breastfeeding is typically not recommended. Chloramphenicol is a broad-spectrum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetylcysteine
Acetylcysteine, also known as ''N''-acetylcysteine (NAC), is a medication that is used to treat paracetamol overdose and to loosen thick mucus in individuals with chronic bronchopulmonary disorders like pneumonia and bronchitis. It has been used to treat lactobezoar in infants. It can be taken intravenously, by mouth, or inhaled as a mist. Some people use it as a dietary supplement. Common side effects include nausea and vomiting when taken by mouth. The skin may occasionally become red and itchy with any route of administration. A non-immune type of anaphylaxis may also occur. It appears to be safe in pregnancy. For paracetamol overdose, it works by increasing the level of glutathione, an antioxidant that can neutralise the toxic breakdown products of paracetamol. When inhaled, it acts as a mucolytic by decreasing the thickness of mucus. Acetylcysteine was initially patented in 1960 and came into medical use in 1968. It is on the World Health Organization's List of Essentia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lugano
Lugano (, , ; lmo, label=Ticinese dialect, Ticinese, Lugan ) is a city and municipality in Switzerland, part of the Lugano District in the canton of Ticino. It is the largest city of both Ticino and the Italian-speaking southern Switzerland. Lugano has a population () of , and an urban agglomeration of over 150,000. It is the List of cities in Switzerland, ninth largest Swiss city. The city lies on Lake Lugano, at its largest width, and, together with the adjacent town of Paradiso, Switzerland, Paradiso, occupies the entire bay of Lugano. The territory of the municipality encompasses a much larger region on both sides of the lake, with numerous isolated villages. The region of Lugano is surrounded by the Lugano Prealps, the latter extending on most of the Sottoceneri region, the southernmost part of Ticino and Switzerland. Both western and eastern parts of the municipality share an international border with Italy. Described as a market town since 984, Lugano was the object of con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cadempino
Cadempino is a municipality in the district of Lugano in the canton of Ticino in Switzerland. History Cadempino is first mentioned in 1004 as ''Cadampinus''. Originally, it was owned by the Totoniden family of Campione d'Italia. In 844 their lands, including Cadempino, were given to the monastery of S. Ambrogio in Milan. By 1004, Como Cathedral and the Abbey of San Pietro in Ciel d'Oro in Pavia, also owned property in the village. In the 14th Century the Church of SS Gervasio e Protasio was mentioned for the first time. It was part of the parish of Lamone in 1468 and in 1910 was raised to a Vicariate. The grazing rights to the alpine meadows of Alp Traverno and Alp Guzzala were originally shared by Cadempino and Lamone. In 1507 Cadempino's rights were given to Isone. The shared grazing lands and disagreements over the border between Cadempino and Lamone led to a long-running disagreement. The two municipalities continued to fight over their mutual border until 1887. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ultra Levura
adopted by British military intelligence in June 1941 for wartime signals intelligence obtained by breaking high-level encrypted enemy radio and teleprinter communications at the Government Code and Cypher School (GC&CS) at Bletchley Park. ''Ultra'' eventually became the standard designation among the western Allies for all such intelligence. The name arose because the intelligence obtained was considered more important than that designated by the highest British security classification then used (''Most Secret'') and so was regarded as being ''Ultra Secret''. Several other cryptonyms had been used for such intelligence. The code name ''Boniface'' was used as a cover name for ''Ultra''. In order to ensure that the successful code-breaking did not become apparent to the Germans, British intelligence created a fictional MI6 master spy, Boniface, who controlled a fictional series of agents throughout Germany. Information obtained through code-breaking was often attributed to th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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