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Yamagiwa Katsusaburō
was a Japanese pathologist who carried out pioneering work into the causes of cancer. He was the first to prove chemical carcinogenesis. He was the Nobel Prize nominee in 7 nominations. Life Yamagiwa was born in Ueda, Nagano, the third son of the feudal retainer of the Ueda Domain in Shinano Province. He became the adopted son-in-law of Yoshiya Yamagiwa, a physician in Katsuya, Tokyo, and took the surname Yamagiwa. He completed his MD in 1888 from Imperial University of Tokyo. He was appointed as a professor at the Medical School, Imperial University of Tokyo and published his landmark work, ''Byōri Sōron Kōgi'', in 1895. Yamagiwa extensively promoted cancer research in Japan. In 1907 ''Cancer Science'', peer-reviewed medical journal covering research in oncology, was first issued by him. In addition, he and his colleagues found the Japanese Foundation for Cancer Research in 1908. He died in Tokyo of pneumonia in 1930 at the age of 67. Contributions In a series of ex ...
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Ueda, Nagano
is a city located in Nagano Prefecture, Japan. , the city had an estimated population of 157,480 in 67,783 households, and a population density of 290 persons per km2. The total area of the city is , which makes it the fifth largest city in Nagano Prefecture in terms of area. Geography Ueda is located in central Nagano Prefecture, some 40 kilometers from the prefectural capital of Nagano City and 190 kilometers from Tokyo. The Chikuma River divides the city into two parts. Surrounding municipalities *Nagano Prefecture ** Matsumoto ** Tōmi ** Suzaka ** Nagano ** Chikuma ** Nagawa ** Aoki ** Chikuhoku * Gunma Prefecture ** Tsumagoi Climate The city has a climate characterized by hot and humid summers, and relatively mild winters (Köppen climate classification ''Cwa''). The average annual temperature in Ueda is . The average annual rainfall is with September as the wettest month. The temperatures are highest on average in August, at around , and lowest in January, at arou ...
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Japanese Foundation For Cancer Research
The (JFCR) is a non-profit cancer research organization based in Ariake, Tokyo. The JFCR was founded in 1908 as the first Japanese organization specializing in cancer by Katsusaburō Yamagiwa and his supporters. The Cancer Institute and its attached hospital of JFCR were set up in 1934. The JFCR became a full member of the Union for International Cancer Control in 1968. Research The Cancer Institute of JFCR is one of the leading medical and biological research institutes in Japan. When the American journal ''Science'' published a special feature on science in Japan in 1992, the institute was described as one of the most productive and most cited institutions in the world at the time. The research at the Institute covers a wide variety of biomedical fields, including biochemistry, cell biology, pathology, carcinogenesis, genomics, system biology, and biomedical engineering. Achievements include the following. *1979: Tadatsugu Taniguchi isolated interferon gene. *1983: Mitsuaki ...
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1930 Deaths
Year 193 ( CXCIII) was a common year starting on Monday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Sosius and Ericius (or, less frequently, year 946 ''Ab urbe condita''). The denomination 193 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * January 1 – Year of the Five Emperors: The Roman Senate chooses Publius Helvius Pertinax, against his will, to succeed the late Commodus as Emperor. Pertinax is forced to reorganize the handling of finances, which were wrecked under Commodus, to reestablish discipline in the Roman army, and to suspend the food programs established by Trajan, provoking the ire of the Praetorian Guard. * March 28 – Pertinax is assassinated by members of the Praetorian Guard, who storm the imperial palace. The Empire is auctioned of ...
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1863 Births
Events January–March * January 1 – Abraham Lincoln signs the Emancipation Proclamation during the third year of the American Civil War, making the abolition of slavery in the Confederate states an official war goal. It proclaims the freedom of 3.1 million of the nation's four million slaves and immediately frees 50,000 of them, with the rest freed as Union armies advance. * January 2 – Lucius Tar Painting Master Company (''Teerfarbenfabrik Meirter Lucius''), predecessor of Hoechst, as a worldwide chemical manufacturing brand, founded in a suburb of Frankfurt am Main, Germany. * January 4 – The New Apostolic Church, a Christian and chiliastic church, is established in Hamburg, Germany. * January 7 – In the Swiss canton of Ticino, the village of Bedretto is partly destroyed and 29 killed, by an avalanche. * January 8 ** The Yorkshire County Cricket Club is founded at the Adelphi Hotel, in Sheffield, England. ** American Civil War – ...
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Cancer Researchers
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as '' Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of a ce ...
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Japanese Pathologists
Japanese may refer to: * Something from or related to Japan, an island country in East Asia * Japanese language, spoken mainly in Japan * Japanese people, the ethnic group that identifies with Japan through ancestry or culture ** Japanese diaspora, Japanese emigrants and their descendants around the world * Japanese citizens, nationals of Japan under Japanese nationality law ** Foreign-born Japanese, naturalized citizens of Japan * Japanese writing system, consisting of kanji and kana * Japanese cuisine, the food and food culture of Japan See also * List of Japanese people * * Japonica (other) * Japonicum * Japonicus * Japanese studies Japanese studies ( Japanese: ) or Japan studies (sometimes Japanology in Europe), is a sub-field of area studies or East Asian studies involved in social sciences and humanities research on Japan. It incorporates fields such as the study of Japan ... {{disambiguation Language and nationality disambiguation pages ...
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Folke Henschen
Folke is a parish in the county of Dorset in southern England, situated in the Blackmore Vale, approximately south-east of Sherborne. The parish has an area of and is made of the villages of Folke and Alweston, and the hamlet of Bishops Down. Dorset County Council's 2013 estimate of the population of Folke parish is 270. In the 2011 census figures have been published for the population of Folke parish combined with the small parish of North Wootton to the north; this was 339. The Manor House in the hamlet of Folke dates from about 1500 and adjoins the early 17th-century parish church. The house of Font le Roi, sited by the road towards Sturminster Newton, was built as a gatehouse in the 15th century. Folke Wood Folke Wood is a wood near Folke in Dorset, England. It was planted by the Woodland Trust The Woodland Trust is the largest woodland conservation charity in the United Kingdom and is concerned with the creation, protection, and restoration of ... is nearby. Ref ...
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Squamous Cell Carcinoma
Squamous-cell carcinomas (SCCs), also known as epidermoid carcinomas, comprise a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts. Common types include: * Squamous-cell skin cancer: A type of skin cancer * Squamous-cell carcinoma of the lung: A type of lung cancer * Squamous-cell thyroid carcinoma: A type of thyroid cancer * Esophageal squamous-cell carcinoma: A type of esophageal cancer * Squamous-cell carcinoma of the vagina: A type of vaginal cancer Despite sharing the name "squamous-cell carcinoma", the SCCs of different body sites can show differences in their presented symptoms, natural history, prognosis, and response to treatment. By body location Human papillomavirus infection has been associated with SCCs of the oropharynx, lung, fingers, and anogenital region. Head and neck cancer About 90% of cases ...
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Spiroptera Carcinoma
''Gongylonema neoplasticum'' (more famously as ''Spiroptera carcinoma'') is a roundworm parasite of rats. It was discovered by a Danish physician Johannes Fibiger in 1907. Fibiger and Hjalmar Ditlevsen made a formal description in 1914 as ''Spiroptera'' (''Gongylonema'') ''neoplastica''. But Ditlevsen gave the final valid name ''Gongylonema neoplasticum'' in 1918. The nematode is transmitted between rats and cockroaches. When Fibiger discovered the nematode in the stomach of rats, he found that the stomach had tumours. Inspired by the possible link of the nematode and tumour, he performed experiments to induce tumours with nematode infection. He published his experimental success in 1913. The nematode experiment earned Fibiger the 1926 Nobel Prize in Physiology or Medicine, but under controversial circumstances. Moreover, it was later proven that Fibiger came to a wrong conclusion, that the nematode is not carcinogenic. Erling Norrby, who had served as the Permanent Secretary of ...
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Johannes Andreas Grib Fibiger
Johannes Andreas Grib Fibiger (23 April 1867 – 30 January 1928) was a Danish physician and professor of anatomical pathology at the University of Copenhagen. He was the recipient of the 1926 Nobel Prize in Physiology or Medicine "for his discovery of the ''Spiroptera carcinoma''". He demonstrated that the roundworm which he called ''Spiroptera carcinoma'' (but correctly named '' Gongylonema neoplasticum'') could cause stomach cancer (squamous cell carcinoma) in rats and mice. His experimental results were later proven to be a case of mistaken conclusion. Erling Norrby, who had served as the Permanent Secretary of the Royal Swedish Academy of Sciences and Professor and Chairman of Virology at the Karolinska Institute, declared Fibiger's Nobel Prize as "one of the biggest blunders made by the Karolinska Institute." While working at the Institute of Pathological Anatomy of University of Copenhagen, Fibiger discovered new roundworms in 1907 from wild rats. He suspected that the rou ...
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Coal Tar
Coal tar is a thick dark liquid which is a by-product of the production of coke and coal gas from coal. It is a type of creosote. It has both medical and industrial uses. Medicinally it is a topical medication applied to skin to treat psoriasis and seborrheic dermatitis (dandruff). It may be used in combination with ultraviolet light therapy. Industrially it is a railroad tie preservative and used in the surfacing of roads. Coal tar was listed as a known human carcinogen in the first Report on Carcinogens from the U.S. Federal Government. Coal tar was discovered circa 1665 and used for medical purposes as early as the 1800s. Circa 1850, the discovery that it could be used as the main ingredient in synthetic dyes engendered an entire industry. It is on the World Health Organization's List of Essential Medicines. Coal tar is available as a generic medication and over the counter. Side effects include skin irritation, sun sensitivity, allergic reactions, and skin discoloration. ...
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Carcinoma
Carcinoma is a malignancy that develops from epithelial cells. Specifically, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that arises from cells originating in the endodermal, mesodermal or ectodermal germ layer during embryogenesis. Carcinomas occur when the DNA of a cell is damaged or altered and the cell begins to grow uncontrollably and become malignant. It is from the el, καρκίνωμα, translit=karkinoma, lit=sore, ulcer, cancer (itself derived from meaning ''crab''). Classification As of 2004, no simple and comprehensive classification system has been devised and accepted within the scientific community. Traditionally, however, malignancies have generally been classified into various types using a combination of criteria, including: The cell type from which they start; specifically: * Epithelial cells ⇨ carcinoma * Non-hematopoietic mesenchymal cells ⇨ sarcoma * Hematopoietic cells **Bone marrow-de ...
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