Yaba Monkey Tumor Virus
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Yaba Monkey Tumor Virus
The Yaba monkey tumor virus is a type of poxvirus. The first case of the virus was obtained from a colony of rhesus monkeys in Yaba, Lagos, Nigeria. The virus caused the formation of tumors on the bodies of the monkeys. From these tumors the virus was isolated and determined to be its own species of virus. It is a species of the ''Yatapoxvirus'' genus and is closely related to the tanapox. The virus gets its name from the suburb of Yaba, Lagos. Signs and symptoms The Yaba monkey tumor virus is characterized by the formation of cutaneous histiocytomas. These cutaneous histiocytomas may form on the face, palms, digits, forearm, surfaces of the nose, sinuses, lips, palate. The tumors are visible within 4–5 days after infection of the virus. In rhesus monkeys the virus has a tendency to affect the face and sinuses causing large tumors to form. In general the only symptoms of the virus will be the formation of tumors. Virus The Yaba monkey tumor virus (YMTV) is considered a chor ...
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Infectious Disease (medical Speciality)
Infectious diseases or ID, also known as infectiology, is a medical specialty dealing with the diagnosis and treatment of infections. An infectious diseases specialist's practice consists of managing nosocomial ( healthcare-acquired) infections or community-acquired infections and is historically associated with hygiene, epidemiology, clinical microbiology, travel medicine and tropical medicine. Scope Infectious diseases specialists typically serve as consultants to other physicians in cases of complex infections, and often manage patients with HIV/AIDS and other forms of immunodeficiency. Although many common infections are treated by physicians without formal expertise in infectious diseases, specialists may be consulted for cases where an infection is difficult to diagnose or manage. They may also be asked to help determine the cause of a fever of unknown origin. Specialists in infectious diseases can practice both in hospitals (inpatient) and clinics (outpatient). In hospitals ...
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Poxvirus
''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox. Four genera of poxviruses may infect humans: ''Orthopoxvirus'', ''Parapoxvirus'', ''Yatapoxvirus'', ''Molluscipoxvirus''. ''Orthopoxvirus'': smallpox virus (variola), vaccinia virus, cowpox virus, monkeypox virus; ''Parapoxvirus'': orf virus, pseudocowpox, bovine papular stomatitis virus; ''Yatapoxvirus'': tanapox virus, yaba monkey tumor virus; ''Molluscipoxvirus'': molluscum contagiosum virus (MCV). The most common are vaccinia (seen on the Indian subcontinent) and molluscum contagiosum, but monkeypox infections are rising (seen in west and central African rainforest countries). The similarly named disease chickenpox is not a true poxvirus and is caused by the herpesvirus varicella zoster. Etymology ...
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Yaba, Lagos
Yaba is a suburb located on Lagos Mainland, Lagos in Lagos State, Nigeria. There are several federal government institutions in the area, which include Queen's College, the Nigerian Institute of Medical Research, the Yaba College of Technology, Igbobi College, the University of Lagos, the Federal Science and Technical College, and the Federal College of Education (Technical) Akoka. Yaba has one of the busiest market sites in Lagos, known as Tejuosho Market. The old Tejuosho market was demolished in 2008 and rebuilt into a modern shopping complex by the end of 2014. Directly opposite the Yaba market is a psychiatric hospital popularly known by many Lagosians as Yaba Left. Yaba is one of the go-to places for technology renaissance in Africa, with tech startups such as Hotels.ng, Andela, Cc-Hub and many others with a positive impact on the economy. The redevelopment of the Tejuosho Market, which was undertaken as part of the Lagos Megacity Project, has transformed it into a ...
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Nigeria
Nigeria ( ), , ig, Naìjíríyà, yo, Nàìjíríà, pcm, Naijá , ff, Naajeeriya, kcg, Naijeriya officially the Federal Republic of Nigeria, is a country in West Africa. It is situated between the Sahel to the north and the Gulf of Guinea to the south in the Atlantic Ocean. It covers an area of , and with a population of over 225 million, it is the most populous country in Africa, and the world's sixth-most populous country. Nigeria borders Niger in the north, Chad in the northeast, Cameroon in the east, and Benin in the west. Nigeria is a federal republic comprising of 36 states and the Federal Capital Territory, where the capital, Abuja, is located. The largest city in Nigeria is Lagos, one of the largest metropolitan areas in the world and the second-largest in Africa. Nigeria has been home to several indigenous pre-colonial states and kingdoms since the second millennium BC, with the Nok civilization in the 15th century BC, marking the first ...
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Yatapoxvirus
''Yatapoxvirus'' is a genus of viruses, in the family ''Poxviridae'', in the subfamily ''Chordopoxvirinae''. Monkeys and baboons serve as natural hosts. There are two species in this genus. Diseases associated with this genus include: histiocytomas, tumor-like mass of mononuclear cells. Taxonomy The genus contains the following species: * ''Tanapox virus'' * ''Yaba monkey tumor virus The Yaba monkey tumor virus is a type of poxvirus. The first case of the virus was obtained from a colony of rhesus monkeys in Yaba, Lagos, Nigeria. The virus caused the formation of tumors on the bodies of the monkeys. From these tumors the virus ...'' Structure Viruses in ''Yatapoxvirus'' are enveloped, with brick-shaped geometries. The diameter is around 200 nm. Genomes are linear, around 145kb in length. Life cycle Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host glycosaminoglycans (GAGs) mediates endocytosis of the viru ...
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Tanapox
Tanapox (a virus from the genus ''Yatapoxvirus'') was first seen among individuals in the flood plain of the Tana River in Kenya during two epidemics (1957 and 1962) of acute febrile illness accompanied by localized skin lesions. Signs and symptoms The incubation period in human cases remains unknown, but in a person who underwent voluntary inoculation, erythema and central thickening appear by the fourth day. Most patients present a mild pre-eruptive fever that lasts 3–4 days, severe headaches and backaches, and often itching at the site where the skin lesion develops. There is initially a small nodule, without any central abrasion. This small nodule soon becomes papular and gradually enlarges to reach a maximum diameter of about 15 mm by the end of the second week of infection. The draining lymph nodes are also enlarged and tender from about the fifth day following the appearance of the skin lesion. The lesion remains mostly nodular but, ulcerates during the third week ...
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Tanapox
Tanapox (a virus from the genus ''Yatapoxvirus'') was first seen among individuals in the flood plain of the Tana River in Kenya during two epidemics (1957 and 1962) of acute febrile illness accompanied by localized skin lesions. Signs and symptoms The incubation period in human cases remains unknown, but in a person who underwent voluntary inoculation, erythema and central thickening appear by the fourth day. Most patients present a mild pre-eruptive fever that lasts 3–4 days, severe headaches and backaches, and often itching at the site where the skin lesion develops. There is initially a small nodule, without any central abrasion. This small nodule soon becomes papular and gradually enlarges to reach a maximum diameter of about 15 mm by the end of the second week of infection. The draining lymph nodes are also enlarged and tender from about the fifth day following the appearance of the skin lesion. The lesion remains mostly nodular but, ulcerates during the third week ...
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Chordopoxvirinae
''Chordopoxvirinae'' is a subfamily of viruses in the family ''Poxviridae''. Humans, vertebrates, and arthropods serve as natural hosts. Currently, 52 species are placed in this subfamily, divided among 18 genera. Diseases associated with this subfamily include smallpox. Four genera in this subfamily contain species that infect humans: ''Molluscipoxvirus, Orthopoxvirus, Parapoxvirus'', and ''Yatapoxvirus''. Virology The virions are generally enveloped though the intracellular mature virion form of the virus, which contains a different envelope, and is also infectious. They vary in their shape depending upon the species, but are generally shaped like a brick or as an oval form similar to a rounded brick because they are wrapped by the endoplasmic reticulum. The virion is exceptionally large, around 200 nm in diameter and 300 nm in length, and carries its genome in a single, double-stranded segment of DNA. Genomes are linear, around 130-375kb in length. Lifecycle Viral r ...
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