Wolfgang Grodd
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Wolfgang Grodd
Prof. Dr. med. Wolfgang Grodd (born 25 July 1942 in Detmold) is a German neuroradiologist and professor emeritus of the University hospital at the University of Tübingen. He is known for his scientific works on the development and application of structural and functional magnetic resonance imaging in metabolic diseases, sensorimotor representation, language production, and cognitive processing, cerebellum, thalamus, and basal ganglia. Currently, Wolfgang Grodd is a research scientist at the Department of the High-Field MR at the Max Planck Institute for Biological Cybernetics. Biography After serving as a temporary soldier in the German Army from 1959 to 1964 and training as an electronics technician, W. Grodd obtained his Abitur (high school diploma) in 1968 at Westfalen Kolleg in Bielefeld and studied biology from 1968 to 1977 and medicine from 1974 to 1981 at the University of Tübingen. From 1972 to 1975 he was a scholarship holder of the Protestant Student Union Villigst. ...
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Detmold
Detmold () is a city in North Rhine-Westphalia, Germany, with a population of . It was the capital of the small Principality of Lippe from 1468 until 1918 and then of the Free State of Lippe until 1947. Today it is the administrative center of the district of Lippe and of the Regierungsbezirk Detmold. The Church of Lippe has its central administration located in Detmold. The Reformed Redeemer Church is the preaching venue of the state superintendent of the Lippe church. History Iron Age About to the southwest of Detmold is the hill with a prehistoric circular rampart and the Hermann monument (german: Hermannsdenkmal). The monument commemorates the so-called Battle of the Teutoburg Forest, a battle in 9 AD which may or may not have been fought close to the present location of Detmold. In this encounter, Germanic tribes led by Hermann ( la, Arminius) defeated Roman legions under the command of Publius Quinctilius Varus. Middle Ages Detmold was first mentioned as ''Theotma ...
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Sociopathy
Psychopathy, sometimes considered synonymous with sociopathy, is characterized by persistent antisocial behavior, impaired empathy and remorse, and bold, disinhibited, and egotistical traits. Different conceptions of psychopathy have been used throughout history that are only partly overlapping and may sometimes be contradictory. Hervey M. Cleckley, an American psychiatrist, influenced the initial diagnostic criteria for antisocial personality reaction/disturbance in the ''Diagnostic and Statistical Manual of Mental Disorders'' (''DSM''), as did American psychologist George E. Partridge. The ''DSM'' and ''International Classification of Diseases'' (ICD) subsequently introduced the diagnoses of antisocial personality disorder (ASPD) and dissocial personality disorder (DPD) respectively, stating that these diagnoses have been referred to (or include what is referred to) as psychopathy or sociopathy. The creation of ASPD and DPD was driven by the fact that many of the classic ...
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People From Detmold
A person (plural, : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal obligation, legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its us ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Somatotopic Arrangement
Somatotopy is the point-for-point correspondence of an area of the body to a specific point on the central nervous system. Typically, the area of the body corresponds to a point on the primary somatosensory cortex (postcentral gyrus). This cortex is typically represented as a sensory homunculus which orients the specific body parts and their respective locations upon the homunculus. Areas such as the appendages, digits, penis, and face can draw their sensory locations upon the somatosensory cortex. The areas which are finely controlled (e.g., the digits) have larger portions of the somatosensory cortex whereas areas which are coarsely controlled (e.g., the trunk) have smaller portions. Areas such as the viscera do not have sensory locations on the post central gyrus. Macaques, a kind of monkey, already exhibit somatotopy in their somatosensory and motor systems at birth. Sensorimotor mapping of the human cerebellum Functional magnetic resonance imaging (fMRI) was employed to dete ...
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Thalamus
The thalamus (from Greek θάλαμος, "chamber") is a large mass of gray matter located in the dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, allowing hub-like exchanges of information. It has several functions, such as the relaying of sensory signals, including motor signals to the cerebral cortex and the regulation of consciousness, sleep, and alertness. Anatomically, it is a paramedian symmetrical structure of two halves (left and right), within the vertebrate brain, situated between the cerebral cortex and the midbrain. It forms during embryonic development as the main product of the diencephalon, as first recognized by the Swiss embryologist and anatomist Wilhelm His Sr. in 1893. Anatomy The thalamus is a paired structure of gray matter located in the forebrain which is superior to the midbrain, near the center of the brain, with nerve fibers projecting out to the ...
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Cerebellum
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebellum plays an important role in motor control. It may also be involved in some cognition, cognitive functions such as attention and language as well as emotion, emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to Motor coordination, coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in Fine motor skill, fine movement, Equilibrioception, equilibrium, Human positions, posture, and motor learning in humans. Anatomica ...
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Speech Production
Speech production is the process by which thoughts are translated into speech. This includes the selection of words, the organization of relevant grammatical forms, and then the articulation of the resulting sounds by the motor system using the vocal apparatus. Speech production can be spontaneous such as when a person creates the words of a conversation, reactive such as when they name a picture or read aloud a written word, or imitative, such as in speech repetition. Speech production is not the same as language production since language can also be produced manually by signs. In ordinary fluent conversation people pronounce roughly four syllables, ten or twelve phonemes and two to three words out of their vocabulary (that can contain 10 to 100 thousand words) each second. Errors in speech production are relatively rare occurring at a rate of about once in every 900 words in spontaneous speech. Words that are commonly spoken or learned early in life or easily imagined are quick ...
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Dementia
Dementia is a disorder which manifests as a set of related symptoms, which usually surfaces when the brain is damaged by injury or disease. The symptoms involve progressive impairments in memory, thinking, and behavior, which negatively affects a person's ability to function and carry out everyday activities. Aside from memory impairment and a disruption in thought patterns, the most common symptoms include emotional problems, difficulties with language, and decreased motivation. The symptoms may be described as occurring in a continuum over several stages. Consciousness is not affected. Dementia ultimately has a significant effect on the individual, caregivers, and on social relationships in general. A diagnosis of dementia requires the observation of a change from a person's usual mental functioning, and a greater cognitive decline than what is caused by normal aging. Several diseases and injuries to the brain, such as a stroke, can give rise to dementia. However, th ...
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Alzheimer Disease
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years. The cause of Alzheimer's disease is poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of APOE. Other risk factors include a history of head injury, clinical depression, and high blood pressure ...
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Functional Imaging
Functional imaging (or physiological imaging) is a medical imaging technique of detecting or measuring changes in metabolism, blood flow, regional chemical composition, and absorption. As opposed to structural imaging, functional imaging centers on revealing physiological activities within a certain tissue or organ by employing medical image modalities that very often use tracers or probes to reflect spatial distribution of them within the body. These tracers are often analogous to some chemical compounds, like glucose, within the body. To achieve this, isotopes are used because they have similar chemical and biological characteristics. By appropriate proportionality, the nuclear medicine physicians can determine the real intensity of certain substance within the body to evaluate the risk or danger of developing some diseases. Modalities * Positron emission tomography (PET) ** Fludeoxyglucose for Glucose metabolism ** O-15 as a flow tracer * Single-photon emission computed t ...
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Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated between the Baltic and North seas to the north, and the Alps to the south; it covers an area of , with a population of almost 84 million within its 16 constituent states. Germany borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its financial centre is Frankfurt; the largest urban area is the Ruhr. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the bulk of the Holy Roman Empire. During the 16th ce ...
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