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Widnes Laboratory
The Widnes Laboratory was a research institute in northern Cheshire, run by Imperial Chemical Industries. History The site opened in 1891 as the Central Laboratory. On Monday 7 August 1950, an explosion at the site killed one man and injured another. Discovery of halothane Work was carried out at Widnes Laboratory from 1951 to 1956 which led to the discovery of halothane in 1955. Halothane gas was the most common anaesthetic for many years. There had been deaths with halothane and liver damage, and was discontinued from the 1980s. Anaesthetic deployment in hospitals is mostly with intravenous compounds and then isoflurane gas, discovered by Ross Terrell in the US. Structure The site was demolished, and now lies under the A533. See also * Winnington Laboratory The Winnington Laboratory was a former chemical laboratory at Winnington, near Northwich, in Cheshire, England. History The Winnington Works were built in 1874. The laboratory was set up by the ICI Alkali Divis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Widnes
Widnes ( ) is an Industrial city, industrial town in the Borough of Halton, Cheshire, England, which at the 2011 United Kingdom census, 2011 census had a population of 61,464. Historic counties of England, Historically in Lancashire, it is on the northern bank of the River Mersey where the estuary narrows to form the Runcorn Gap. Directly to the south across the Mersey is the town of Runcorn. Upstream to the east is Warrington, and 4 miles downstream to the west is Speke, a suburb of Liverpool. Before the Industrial Revolution, Widnes was a small settlement on marsh and moorland. In 1847, the chemist and industrialist John Hutchinson (industrialist), John Hutchinson established a chemical factory at Spike Island, Widnes, Spike Island. The town grew in population and rapidly became a major centre of the chemical industry. The demand for labour was met by large-scale immigration from Ireland, Poland, Lithuania and Wales. The town continues to be a major manufacturer of chemicals, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cheshire
Cheshire ( ) is a ceremonial and historic county in North West England, bordered by Wales to the west, Merseyside and Greater Manchester to the north, Derbyshire to the east, and Staffordshire and Shropshire to the south. Cheshire's county town is the cathedral city of Chester, while its largest town by population is Warrington. Other towns in the county include Alsager, Congleton, Crewe, Ellesmere Port, Frodsham, Knutsford, Macclesfield, Middlewich, Nantwich, Neston, Northwich, Poynton, Runcorn, Sandbach, Widnes, Wilmslow, and Winsford. Cheshire is split into the administrative districts of Cheshire West and Chester, Cheshire East, Halton, and Warrington. The county covers and has a population of around 1.1 million as of 2021. It is mostly rural, with a number of towns and villages supporting the agricultural and chemical industries; it is primarily known for producing chemicals, Cheshire cheese, salt, and silk. It has also had an impact on popular culture, producin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Imperial Chemical Industries
Imperial Chemical Industries (ICI) was a British chemical company. It was, for much of its history, the largest manufacturer in Britain. It was formed by the merger of four leading British chemical companies in 1926. Its headquarters were at Millbank in London. ICI was a constituent of the FT 30 and later the FTSE 100 indices. ICI made general chemicals, plastics, paints, pharmaceuticals and speciality products, including food ingredients, speciality polymers, electronic materials, fragrances and flavourings. In 2008, it was acquired by AkzoNobel, which immediately sold parts of ICI to Henkel and integrated ICI's remaining operations within its existing organisation. History Development of the business (1926–1944) The company was founded in December 1926 from the merger of four companies: Brunner Mond, Nobel Explosives, the United Alkali Company, and British Dyestuffs Corporation. It established its head office at Millbank in London in 1928. Competing with DuPont a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catalyst - ICI General Chemicals Widnes Research Laboratory Blue Plaque
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quickly, very small amounts of catalyst often suffice; mixing, surface area, and temperature are important factors in reaction rate. Catalysts generally react with one or more reactants to form intermediates that subsequently give the final reaction product, in the process of regenerating the catalyst. Catalysis may be classified as either homogeneous, whose components are dispersed in the same phase (usually gaseous or liquid) as the reactant, or heterogeneous, whose components are not in the same phase. Enzymes and other biocatalysts are often considered as a third category. Catalysis is ubiquitous in chemical industry of all kinds. Estimates are that 90% of all commercially produced chemical products involve catalysts at some stag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Halothane
Halothane, sold under the brand name Fluothane among others, is a general anaesthetic. It can be used to induce or maintain anaesthesia. One of its benefits is that it does not increase the production of saliva, which can be particularly useful in those who are difficult to intubate. It is given by inhalation. Side effects include an irregular heartbeat, respiratory depression, and hepatotoxicity. Like all volatile anesthetics, it should not be used in people with a personal or family history of malignant hyperthermia. It appears to be safe in porphyria. It is unclear whether use during pregnancy is harmful to the baby, and it is not generally recommended for use during a C-section. Halothane is a chiral molecule that is used as a racemic mixture. Halothane was discovered in 1955. It was approved for medical use in the United States in 1958. It is on the World Health Organization's List of Essential Medicines. Its use in developed countries has been mostly replaced by newer ane ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isoflurane
Isoflurane, sold under the brand name Forane among others, is a general anesthetic. It can be used to start or maintain anesthesia; however, other medications are often used to start anesthesia rather than isoflurane, due to airway irritation with isoflurane. Isoflurane is given via inhalation. Side effects of isoflurane include a decreased ability to breathe (respiratory depression), low blood pressure, and an irregular heartbeat. Serious side effects can include malignant hyperthermia or high blood potassium. It should not be used in patients with a history of malignant hyperthermia in either themselves or their family members. It is unknown if its use during pregnancy is safe for the fetus, but use during a cesarean section appears to be safe. Isoflurane is a halogenated ether. Isoflurane was approved for medical use in the United States in 1979. It is on the World Health Organization's List of Essential Medicines. Medical uses Isoflurane is always administered in con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ross Terrell
Ross or ROSS may refer to: People * Clan Ross, a Highland Scottish clan * Ross (name), including a list of people with the surname or given name Ross, as well as the meaning * Earl of Ross, a peerage of Scotland Places * RoSS, the Republic of South Sudan Antarctica * Ross Sea * Ross Ice Shelf * Ross Dependency Australia * Ross, Tasmania Chile * Ross Casino, a former casino in Pichilemu, Chile; now the Agustín Ross Cultural Centre Ireland *"Ross", a common nickname for County Roscommon * Ross, County Mayo, a townland in Killursa civil parish, barony of Clare, County Mayo, bordering Moyne Townland * Ross, County Westmeath, a townland in Noughaval civil parish, barony of Kilkenny West, County Westmeath * Ross, County Wexford * The Diocese of Ross in West Cork. The Roman Catholic diocese merged with Cork in 1958 to become the Roman Catholic Diocese of Cork and Ross, while the Church of Ireland diocese is now part of the Diocese of Cork, Cloyne and Ross. This area, centered ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
A533 Road
The A533 road or the Bridgewater Expressway is a road linking Rode Heath in Cheshire, England with Widnes, also in Cheshire. Route The road follows this route: *Rode Heath () *Sandbach *Middlewich *Northwich *Runcorn *Widnes () Primary route status The road is a primary route between Middlewich and Runcorn. The route also covers the Silver Jubilee Bridge The Silver Jubilee Bridge (originally the Runcorn–Widnes Bridge or informally the Runcorn Bridge) crosses the River Mersey and the Manchester Ship Canal at River Mersey#Runcorn Gap, Runcorn Gap between Runcorn and Widnes in Borough of Halton .... References Roads in England Roads in Cheshire {{England-road-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Winnington Laboratory
The Winnington Laboratory was a former chemical laboratory at Winnington, near Northwich, in Cheshire, England. History The Winnington Works were built in 1874. The laboratory was set up by the ICI Alkali Division of Imperial Chemical Industries. The chemist Francis Arthur Freeth arrived in 1907, and became head of the laboratory. ICI was formed in 1926. Discovery of polythene On 24 March 1933 two scientists conducted an experiment that produced polythene (polyethylene). Benzaldehyde was reacted with ethene ( ethylene) at 2,000 atmospheres pressure. Sir Michael Perrin worked with this group of scientists from October 1933 until 1938. In December 1935 he conducted an experiment that allowed polythene to be created. Polythene is the world's most widespread plastic. In 1958, manufacture of polythene was moved to ICI's plant in Hertfordshire (ICI Plastics). Structure The laboratory was off the A533 next to the River Weaver and south of Barnton, Cheshire. The nearby chem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1891 Establishments In England
Events January–March * January 1 ** Paying of old age pensions begins in Germany. ** A strike of 500 Hungarian steel workers occurs; 3,000 men are out of work as a consequence. **Germany takes formal possession of its new African territories. * January 2 – A. L. Drummond of New York is appointed Chief of the Treasury Secret Service. * January 4 – The Earl of Zetland issues a declaration regarding the famine in the western counties of Ireland. * January 5 **The Australian shearers' strike, that leads indirectly to the foundation of the Australian Labor Party, begins. **A fight between the United States and Indians breaks out near Pine Ridge agency. ** Henry B. Brown, of Michigan, is sworn in as an Associate Justice of the Supreme Court. **A fight between railway strikers and police breaks out at Motherwell, Scotland. * January 6 – Encounters continue, between strikers and the authorities at Glasgow. * January 7 ** General Miles' forces s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Industry In The United Kingdom
The chemical industry in the United Kingdom is one of the UK's main manufacturing industries. At one time, the UK's chemical industry was a world leader. The industry has also been environmentally damaging, and includes radioactive nuclear industries. History Sir William Henry Perkin FRS discovered the first synthetic dye mauveine in 1856, produced from aniline, having tried to synthesise quinine at his home on Cable Street in east London. Perkin's work, alone, led the way to the British chemical industry. 21% of the UK's chemical industry is in North West England, notably around Runcorn and Widnes. The chemical industry is 6.8% of UK manufacturing; around 85% of the UK chemical industry is in England. It employs 500,000, including 350,000 indirectly. It accounts for around 20% of the UK's research and development. Output In 2015, the UK chemical industry exported £50bn of products. The industry employs about 30,000 in research and development. Regulation Regulation of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Research Institutes
A chemical substance is a form of matter having constant chemical composition and characteristic properties. Some references add that chemical substance cannot be separated into its constituent elements by physical separation methods, i.e., without breaking chemical bonds. Chemical substances can be simple substances (substances consisting of a single chemical element), chemical compounds, or alloys. Chemical substances are often called 'pure' to set them apart from mixtures. A common example of a chemical substance is pure water; it has the same properties and the same ratio of hydrogen to oxygen whether it is isolated from a river or made in a laboratory. Other chemical substances commonly encountered in pure form are diamond (carbon), gold, table salt (sodium chloride) and refined sugar (sucrose). However, in practice, no substance is entirely pure, and chemical purity is specified according to the intended use of the chemical. Chemical substances exist as solids, liquids, g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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