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Wolf-dog Hybrid
A wolfdog is a canine produced by the mating of a domestic dog (''Canis familiaris'') with a gray wolf (''Canis lupus''), eastern wolf (''Canis lycaon''), red wolf (''Canis rufus''), or Ethiopian wolf (''Canis simensis'') to produce a hybrid. Admixture There are a range of experts who believe that they can tell the difference between a wolf, a dog, and a wolfdog, but they have been proven to be incorrect when providing their evidence before courts of law. Admixture between domestic dogs and other subspecies of gray wolves are the most common wolfdogs since dogs and gray wolves are considered the same species, are genetically very close and have shared vast portions of their ranges for millennia. Such admixture in the wild have been detected in many populations scattered throughout Europe and North America, usually occurring in areas where wolf populations have declined from human impacts and persecutions. At the same time, wolfdogs are also often bred in captivity for v ...
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Arctic Wolf
The Arctic wolf (''Canis lupus arctos''), also known as the white wolf or polar wolf, is a subspecies of grey wolf native to the High Arctic tundra of Canada's Queen Elizabeth Islands, from Melville Island to Ellesmere Island.https://ecoregions.appspot.com/ Unlike some populations that move between tundra and forest regions, Arctic wolves spend their entire lives north of the northern treeline. Their distribution to south is limited to the northern fringes of the Middle Arctic tundra on the southern half of Prince of Wales and Somerset Islands. It is a medium-sized subspecies, distinguished from the northwestern wolf by its smaller size, its whiter colouration, its narrower braincase,Goldman, E. A. (1964). Classification of wolves. In ''The Wolves of North America'' Part 2. Young, S. P. & Goldman, E. A. (Eds.) New York: Dover Publs. p. 430. and larger carnassials. Since 1930, there has been a progressive reduction in size in Arctic wolf skulls, which is likely the result o ...
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Fédération Cynologique Internationale
The Fédération cynologique internationale (FCI) (English: International Canine Federation) is the largest international federation of national kennel clubs. It is based in Thuin, Belgium. History The FCI was founded in 1911 under the auspices of the kennel clubs of Austria, Belgium, France, Germany and the Netherlands, its objective was to bring global uniformity to the breeding, exhibiting and judging of pure-bred dogs. It was disbanded in World War I and recreated in 1921 by Belgium and France. Since its foundation the FCI's membership has grown to include kennel clubs from across Europe as well as Africa, the Americas, Asia and Oceania. The official purebred registries in North America that are not members or contract partners of FCI include the American Kennel Club (AKC), Canadian Kennel Club (CKC) and United Kennel Club (UKC), and in Europe, The Kennel Club (TKC). According to AKC's Denise Flaim, crafting a workable standard is a challenge, and the "FCI standards typical ...
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Apennines
The Apennines or Apennine Mountains (; grc-gre, links=no, Ἀπέννινα ὄρη or Ἀπέννινον ὄρος; la, Appenninus or  – a singular with plural meaning;''Apenninus'' (Greek or ) has the form of an adjective, which would be segmented ''Apenn-inus'', often used with nouns such as ("mountain") or Greek (), but ''Apenninus'' is just as often used alone as a noun. The ancient Greeks and Romans typically but not always used "mountain" in the singular to mean one or a range; thus, "the Apennine mountain" refers to the entire chain and is translated "the Apennine mountains". The ending can vary also by gender depending on the noun modified. The Italian singular refers to one of the constituent chains rather than to a single mountain, and the Italian plural refers to multiple chains rather than to multiple mountains. it, Appennini ) are a mountain range consisting of parallel smaller chains extending along the length of peninsular Italy. In the northwest th ...
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Italy
Italy ( it, Italia ), officially the Italian Republic, ) or the Republic of Italy, is a country in Southern Europe. It is located in the middle of the Mediterranean Sea, and its territory largely coincides with the homonymous geographical region. Italy is also considered part of Western Europe, and shares land borders with France, Switzerland, Austria, Slovenia and the enclaved microstates of Vatican City and San Marino. It has a territorial exclave in Switzerland, Campione. Italy covers an area of , with a population of over 60 million. It is the third-most populous member state of the European Union, the sixth-most populous country in Europe, and the tenth-largest country in the continent by land area. Italy's capital and largest city is Rome. Italy was the native place of many civilizations such as the Italic peoples and the Etruscans, while due to its central geographic location in Southern Europe and the Mediterranean, the country has also historically been home ...
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Beta-defensin 3
Beta-defensin 3 is a protein that in humans is encoded by the ''DEFB3'' gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba .... HBD-3 was first isolated from human lesional psoriatic scales. RT-PCR showed HBD-3 to be expressed highly in skin, trachea, tongue and tonsils, with lower levels found salivary glands, uterus, kidney, bone marrow, thymus, colon, stomach, adenoid, pharynx, and larynx. References {{reflist Peripheral membrane proteins Defensins ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutation is the ultimate source o ...
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Adolph Murie
Adolph Murie (September 6, 1899 – August 16, 1974), the first scientist to study wolves in their natural habitat, was a naturalist, author, and wildlife biologist who pioneered field research on wolves, bears, and other mammals and birds in Arctic and sub-Arctic Alaska. He was also instrumental in protecting wolves from eradication and in preserving the biological integrity of the Denali National Park and the Arctic National Wildlife Refuge. In 1989 Professor John A. Murray of the English Department at the University of Alaska, Fairbanks received an NEH grant to inventory the extensive Adolph Murie written and slide archives at Rasmusson Library in the Arctic and Polar Collection. He wrote a forty-page report and biographical narrative of Adolph Murie, which remains unpublished but which is in his papers. Early life Adolf Winstrom was born on September 6, 1899, in Moorhead, Minnesota, the child of Ed and Marie Winstrom. In 1922, prior to completing college, Adolph Murie joined ...
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Teotihuacan
Teotihuacan (Spanish language, Spanish: ''Teotihuacán'') (; ) is an ancient Mesoamerican city located in a sub-valley of the Valley of Mexico, which is located in the State of Mexico, northeast of modern-day Mexico City. Teotihuacan is known today as the site of many of the most architecturally significant Mesoamerican pyramids built in the pre-Columbian Americas, namely Pyramid of the Sun and Pyramid of the Moon. At its zenith, perhaps in the first half of the first millennium (1 CE to 500 CE), Teotihuacan was the largest city in the Americas, with a population estimated at 125,000 or more, making it at least the sixth-largest city in the world during its epoch. The city covered eight square miles (21 km2), and 80 to 90 percent of the total population of the valley resided in Teotihuacan. Apart from the pyramids, Teotihuacan is also anthropologically significant for its complex, multi-family residential compounds, the Avenue of the Dead, and its vibrant, well-prese ...
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Sarloos Wolfdog
The Saarloos Wolfdog ( nl, Saarlooswolfhond, german: Saarlooswolfhund) is a wolf-dog breed originating from the Netherlands by the crossing of a German Shepherd with a Siberian grey wolf in 1935. The offspring were then further crossed with German Shepherds. History Leendert Saarloos (1884–1969) was a Dutch zoologist and dog breeder who believed that the German Shepherd had become too domesticated and wanted to breed back the more natural properties in order to derive a better working dog. In 1935, he bred a male German Shepherd (german: Deutscher Schäferhund, nl, Duitse herdershond) to a female Eurasian grey wolf (''Canis lupus lupus'') from Siberia. He then bred the offspring back with German Shepherds to derive a dog with one quarter wolf blood. The result was a dog that was not useful as a working dog but as companion that is close to nature. The Dutch Kennel Club recognized the breed in 1975. To honour its creator, they named this dog the "Saarloos wolfdog". In 19 ...
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Gene Flow
In population genetics, gene flow (also known as gene migration or geneflow and allele flow) is the transfer of genetic material from one population to another. If the rate of gene flow is high enough, then two populations will have equivalent allele frequencies and therefore can be considered a single effective population. It has been shown that it takes only "one migrant per generation" to prevent populations from diverging due to drift. Populations can diverge due to selection even when they are exchanging alleles, if the selection pressure is strong enough. Gene flow is an important mechanism for transferring genetic diversity among populations. Migrants change the distribution of genetic diversity among populations, by modifying allele frequencies (the proportion of members carrying a particular variant of a gene). High rates of gene flow can reduce the genetic differentiation between the two groups, increasing homogeneity. For this reason, gene flow has been thought to con ...
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