William Klyne
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William Klyne
William Klyne (March 23, 1913, in Enfield, Middlesex – November 13, 1977) was an organic chemist known for his work in steroids and stereochemistry — a field in which he was a "pioneer", and in which Ernest Eliel and Norman Allinger described him as "one of the world's experts". Klyne taught at Westfield College, University of London, where he served as dean of science from 1971 to 1973, and as vice-principal from 1973 to 1976. He also served on the editorial board of the Biochemical Society from 1950 to 1955, and on IUPAC's nomenclature committee from 1971 until his death. As well, he established and maintained the Medical Research Council's Steroid Reference Collection, and wrote several textbooks, including ''The Chemistry of Steroids'' (1957) and ''Atlas of Stereochemical Correlations'' (1974). Personal life Klyne met Barbara Clayton in 1947 while both were employed at the Medical Research Council; they married in 1949. See also *Klyne–Prelog system In stereoch ...
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Enfield, Middlesex
Enfield is a large town in north London, England, north of Charing Cross. It had a population of 156,858 in 2018. It includes the areas of Botany Bay, Brimsdown, Bulls Cross, Bullsmoor, Bush Hill Park, Clay Hill, Crews Hill, Enfield Highway, Enfield Lock, Enfield Town, Enfield Wash, Forty Hill, Freezywater, Gordon Hill, Grange Park, Hadley Wood, Ponders End, and World's End. South of the Hertfordshire border and M25 motorway, it borders Waltham Cross to the north, Winchmore Hill and Edmonton to the south, Chingford and Waltham Abbey, across the River Lea, to the east and north-east, with Cockfosters, Monken Hadley and Oakwood to the west. Historically an ancient parish in the Edmonton Hundred of Middlesex, it was granted urban district status in 1894 and municipal borough status in 1955. In 1965, it merged with the municipal boroughs of Southgate and Edmonton to create the London Borough of Enfield, a local government district of Greater London, of which Enf ...
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Medical Research Council (UK)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequen ...
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1913 Births
Events January * January 5 – First Balkan War: Battle of Lemnos – Greek admiral Pavlos Kountouriotis forces the Turkish fleet to retreat to its base within the Dardanelles, from which it will not venture for the rest of the war. * January 13 – Edward Carson founds the (first) Ulster Volunteer Force, by unifying several existing loyalist militias to resist home rule for Ireland. * January 23 – 1913 Ottoman coup d'état: Ismail Enver comes to power. * January – Stalin (whose first article using this name is published this month) travels to Vienna to carry out research. Until he leaves on February 16 the city is home simultaneously to him, Hitler, Trotsky and Tito alongside Berg, Freud and Jung and Ludwig and Paul Wittgenstein. February * February 1 – New York City's Grand Central Terminal, having been rebuilt, reopens as the world's largest railroad station. * February 3 – The 16th Amendment to the United S ...
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People From Enfield, London
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of ...
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Alumni Of New College, Oxford
Alumni (singular: alumnus (masculine) or alumna (feminine)) are former students of a school, college, or university who have either attended or graduated in some fashion from the institution. The feminine plural alumnae is sometimes used for groups of women. The word is Latin and means "one who is being (or has been) nourished". The term is not synonymous with "graduate"; one can be an alumnus without graduating (Burt Reynolds, alumnus but not graduate of Florida State, is an example). The term is sometimes used to refer to a former employee or member of an organization, contributor, or inmate. Etymology The Latin noun ''alumnus'' means "foster son" or "pupil". It is derived from PIE ''*h₂el-'' (grow, nourish), and it is a variant of the Latin verb ''alere'' "to nourish".Merriam-Webster: alumnus
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Separate, but from the s ...
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Academics Of Westfield College
An academy ( Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, '' Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulatio ...
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Organic Chemists
Organic may refer to: * Organic, of or relating to an organism, a living entity * Organic, of or relating to an anatomical organ Chemistry * Organic matter, matter that has come from a once-living organism, is capable of decay or is the product of decay, or is composed of organic compounds * Organic compound, a compound that contains carbon ** Organic chemistry, chemistry involving organic compounds Farming, certification and products * Organic farming, agriculture conducted according to certain standards, especially the use of stated methods of fertilization and pest control * Organic certification, accreditation process for producers of organically-farmed products * Organic horticulture, the science and art of growing fruits, vegetables, flowers, or ornamental plants by following the essential principles of organic agriculture * Organic products, "organics": ** Organic food, food produced from organic farming methods and often certified organic according to organic farming stan ...
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Ultraviolet–visible Spectroscopy Of Stereoisomers
Ultraviolet–visible spectroscopy (UV–vis) can distinguish between enantiomers by showing a distinct Cotton effect for each isomer. UV–vis spectroscopy sees only chromophores, so other molecules must be prepared for analysis by chemical addition of a chromophore such as anthracene. Two methods are reported: the octant rule and the exciton chirality method. The octant rule was introduced in 1961 by William Moffitt, R. B. Woodward, A. Moscowitz, William Klyne and Carl Djerassi.''A Simple Computer-Aided Three-Dimensional Molecular Modeling for the Octant Rule'' Yinan Kang , Fu-An Kang J. Chem. Educ., 2011, 88 (4), p 420 This empirical rule allows the prediction of the sign of the Cotton effect by analysing relative orientation of substituents in three dimensions and in this way the absolute configuration Absolute configuration refers to the spatial arrangement of atoms within a chiral molecular entity (or group) and its resultant stereochemical description. Absolute c ...
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Klyne–Prelog System
In stereochemistry, the Klyne–Prelog system (named for William Klyne and Vladimir Prelog) for describing conformations about a single bond offers a more systematic means to unambiguously name complex structures, where the torsional or dihedral angles are not found to occur in 60° increments. Klyne notation views the placement of the substituent on the front atom as being in regions of space called anti/syn and clinal/periplanar relative to a reference group on the rear atom. A plus (+) or minus (–) sign is placed at the front to indicate the sign of the dihedral angle. Anti or syn indicates the substituents are on opposite sides or the same side, respectively. Clinal substituents are found within 30° of either side of a dihedral angle of 60° (from 30° to 90°), 120° (90°–150°), 240° (210°–270°), or 300° (270°–330°). Periplanar substituents are found within 30° of either 0° (330°–30°) or 180° (150°–210°). Juxtaposing the designations produces th ...
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Barbara Clayton
Dame Barbara Evelyn Clayton (2 September 1922 – 11 January 2011) was an English pathologist who made a significant contribution to clinical medicine, medical research and public service. She was latterly Professor of Clinical Pathology at Great Ormond Street Hospital, London. Biography Clayton was born in Liverpool on 2 September 1922 to Constance Evelyn (née Caine) and William Clayton, a food scientist who is credited with inventing salad cream. She was educated at St Nicholas Preparatory School in Orpington and Bromley County School for Girls, where she was head girl. She went on to study medicine at the University of Edinburgh, qualifying in 1946. Her interest in research took her to the Medical Research Council clinical endocrinology unit in Edinburgh. In 1949 she received a PhD for her research into oestrogens in 1949. Later that year she moved to London to become the Holden research fellow at St Thomas's Hospital Medical School, a position she held until 1956 when ...
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Textbook
A textbook is a book containing a comprehensive compilation of content in a branch of study with the intention of explaining it. Textbooks are produced to meet the needs of educators, usually at educational institutions. Schoolbooks are textbooks and other books used in schools. Today, many textbooks are published in both print and digital formats. History The history of textbooks dates back to ancient civilizations. For example, Ancient Greeks wrote educational texts. The modern textbook has its roots in the mass production made possible by the printing press. Johannes Gutenberg himself may have printed editions of ''Ars Minor'', a schoolbook on Latin grammar by Aelius Donatus. Early textbooks were used by tutors and teachers (e.g. alphabet books), as well as by individuals who taught themselves. The Greek philosopher Socrates lamented the loss of knowledge because the media of transmission were changing. Before the invention of the Greek alphabet 2,500 years ago, knowledge an ...
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The Independent
''The Independent'' is a British online newspaper. It was established in 1986 as a national morning printed paper. Nicknamed the ''Indy'', it began as a broadsheet and changed to tabloid format in 2003. The last printed edition was published on Saturday 26 March 2016, leaving only the online edition. The newspaper was controlled by Tony O'Reilly's Irish Independent News & Media from 1997 until it was sold to the Russian oligarch and former KGB Officer Alexander Lebedev in 2010. In 2017, Sultan Muhammad Abuljadayel bought a 30% stake in it. The daily edition was named National Newspaper of the Year at the 2004 British Press Awards. The website and mobile app had a combined monthly reach of 19,826,000 in 2021. History 1986 to 1990 Launched in 1986, the first issue of ''The Independent'' was published on 7 October in broadsheet format.Dennis Griffiths (ed.) ''The Encyclopedia of the British Press, 1422–1992'', London & Basingstoke: Macmillan, 1992, p. 330 It was pro ...
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