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Walter Fiers
Walter Fiers (31 January 1931 in Ypres, West Flanders – 28 July 2019 in Destelbergen) was a Belgian molecular biologist. He obtained a degree of Engineer for Chemistry and Agricultural Industries at the University of Ghent in 1954, and started his research career as an enzymologist in the laboratory of Laurent Vandendriessche in Ghent. In 1956–57, he worked with in Copenhagen (Denmark). In 1960, he obtained a fellowship from the Rockefeller Foundation and joined the group of Bob Sinsheimer as a postdoc. At the California Institute of Technology Walter Fiers was exposed to Molecular Biology, which was then just developing, studying viral DNA. He demonstrated the physical, covalently closed circularity of Bacteriophage PhiX-174 DNA. In 1962, Fiers moved to Madison, Wisconsin, to work in the laboratory of future Nobel laureate, Gobind Khorana. At the end of 1962, Fiers returned to Belgium and set up the Laboratory of Molecular Biology at the University of Ghent. His resear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ypres
Ypres ( , ; nl, Ieper ; vls, Yper; german: Ypern ) is a Belgian city and municipality in the province of West Flanders. Though the Dutch name is the official one, the city's French name is most commonly used in English. The municipality comprises the city of Ypres/Ieper and the villages of Boezinge, Brielen, Dikkebus, Elverdinge, Hollebeke, Sint-Jan, Vlamertinge, Voormezele, Zillebeke, and Zuidschote. Together, they are home to about 34,900 inhabitants. During the First World War, Ypres (or "Wipers" as it was commonly known by the British troops) was the centre of the Battles of Ypres between German and Allied forces. History Origins before First World War Ypres is an ancient town, known to have been raided by the Romans in the first century BC. It is first mentioned by name in 1066 and is probably named after the river Ieperlee on the banks of which it was founded. During the Middle Ages, Ypres was a prosperous Flemish city with a population of 40,000 in 1200 AD, renow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Laureate
The Nobel Prizes ( sv, Nobelpriset, no, Nobelprisen) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make outstanding contributions in the fields of chemistry, physics, literature, peace, and physiology or medicine. They were established by the 1895 will of Alfred Nobel, which dictates that the awards should be administered by the Nobel Foundation. The Nobel Memorial Prize in Economic Sciences was established in 1968 by the Sveriges Riksbank, the central bank of Sweden, for contributions to the field of economics. Each recipient, a Nobelist or ''laureate'', receives a gold medal, a diploma, and a sum of money which is decided annually by the Nobel Foundation. Prize Each prize is awarded by a separate committee; the Royal Swedish Academy of Sciences awards the Prizes in Physics, Chemistry, and Economics; the Karolinska Institute awards the Prize ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Koch Prize
The Robert Koch Medal and Award are two prizes awarded annually by the German for excellence in the biomedical sciences. These awards grew out of early attempts by German physician Robert Koch to generate funding to support his research into the cause and cure for tuberculosis. Koch discovered the bacteria (''Mycobacterium tuberculosis'') responsible for the dreaded disease and rapidly acquired international support, including 500,000 gold marks from the Scottish-American philanthropist Andrew Carnegie. The Robert Koch Prize Since 1970, the Robert Koch Foundation has awarded prizes for major advances in the biomedical sciences, particularly in the fields of microbiology and immunology. The prestige of this award has grown over the past decades so that it is now widely regarded as the leading international scientific prize in microbiology. As has been described by a jury member for the prize, the committee often asks, "What would Robert Koch work on today?” to decide on resea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carlos J
Carlos may refer to: Places ;Canada * Carlos, Alberta, a locality ;United States * Carlos, Indiana, an unincorporated community * Carlos, Maryland, a place in Allegany County * Carlos, Minnesota, a small city * Carlos, West Virginia ;Elsewhere * Carlos (crater), Montes Apenninus, LQ12, Moon; a lunar crater near Mons Hadley People * Carlos (given name), including a list of name holders * Carlos (surname), including a list of name holders Sportspeople * Carlos (Timorese footballer) (born 1986) * Carlos (footballer, born 1995), Brazilian footballer * Carlos (footballer, born 1985), Brazilian footballer Others * Carlos (Calusa) (died 1567), king or paramount chief of the Calusa people of Southwest Florida * Carlos (DJ) (born 1966), British DJ * Carlos (singer) (1943—2008), French entertainer * Carlos the Jackal, a Venezuelan terrorist *Carlos (DJ) (born 2010) Guyanese DJ Arts and entertainment * Carlos (miniseries), ''Carlos'' (miniseries), 2010 biopic about the terrorist Carl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beijerinck Virology Prize
The M.W. Beijerinck Virology Prize (''M.W. Beijerinck Virologie Prijs'') is a prize in virology awarded every two years by the ''Koninklijke Nederlandse Akademie van Wetenschappen'' (KNAW). The prize consists of a medal and a monetary award of €35,000. KNAW's two conditions for the prize nomination are that the nominee must be an internationally recognized researcher who has "made a groundbreaking contribution to research in the field of virology in the broadest sense" and must have an appointment at a university or research institute. The prize is named in honor of the Dutch microbiologist Martinus Willem Beijerinck. KNAW appoints an advisory committee which gives advice to KNAW concerning the prize nominees. KNAW has regulations for who may submit nominations. Before 2014 the prize was awarded every three years. Prize winners *1966 Egbertus van Slogteren, Netherlands *1969 , United States *1972 W. Berends, Netherlands *1975 E.M.J. Jaspars and A. van Kammen, Netherlands * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Francqui Prize
The Francqui Prize is a prestigious Belgian scholarly and scientific prize named after Émile Francqui. Normally annually since 1933, the Francqui Foundation awards it in recognition of the achievements of a scholar or scientist, who at the start of the year still had to be under 50. It currently represents a sum of 250,000 Euros and is awarded in the following three-year rotation of subjects: exact sciences, social sciences or humanities, and biological or medical sciences. Proposed candidates must be associated with a Belgian academic institution, in the case of a foreigner for at least ten years. The recipient is selected by a jury of eight to 14 members, none of whom may be associated with a Belgian institution. The members of the international jury vote by secret letter, and the laureate they recommend must be supported by two thirds of the assembled directors of the foundation (with a quorum of 12) or no prize would be awarded that year. The prize is meant to encourage the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pandemic
A pandemic () is an epidemic of an infectious disease that has spread across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. A widespread endemic (epidemiology), endemic disease with a stable number of infected individuals is not a pandemic. Widespread endemic diseases with a stable number of infected individuals such as recurrences of seasonal influenza are generally excluded as they occur simultaneously in large regions of the globe rather than being spread worldwide. Throughout human history, there have been a number of pandemics of diseases such as smallpox. The most fatal pandemic in recorded history was the Black Death—also known as Plague (disease), The Plague—which killed an estimated 75–200 million people in the 14th century. The term had not been used then but was used for later epidemics, including the 1918 influenza pandemic—more commonly known as the Spanish flu. Current pandemics include Epide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
M2 Protein
The Matrix-2 (M2) protein is a proton-selective viroporin, integral in the viral envelope of the influenza A virus. The channel itself is a homotetramer (consists of four identical M2 units), where the units are helices stabilized by two disulfide bonds, and is activated by low pH. The M2 protein is encoded on the seventh RNA segment together with the M1 protein. Proton conductance by the M2 protein in influenza A is essential for viral replication. Influenza B and C viruses encode proteins with similar function dubbed "BM2" and "CM2" respectively. They share little similarity with M2 at the sequence level, despite a similar overall structure and mechanism. Structure In influenza A virus, M2 protein unit consists of three protein segments comprising 97 amino acid residues: (i) an extracellular N-terminal domain (residues 1–23); (ii) a transmembrane segment (TMS) (residues 24–46); (iii) an intracellular C-terminal domain (residues 47–97). The TMS forms the pore of the ion ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza
Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin from one to four days after exposure to the virus (typically two days) and last for about 2–8 days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia, which can be caused by the virus or by a subsequent bacterial infection. Other complications of infection include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus, termed influenza viruses A, B, C, and D. Aquatic birds are the primary source of Influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and Influenza C virus (ICV) pri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xavier Saelens
Xavier Saelens (born 1965) is a Belgian scientist and currently his main research interest is finding a universal influenza vaccine. He is a lecturer in Virology and Group Leader of the Molecular Virology Unit at the University of Ghent (Ghent, Belgium). Education He obtained a bachelor's degree in Biology at the University of Ghent in 1985, and a master's degree in Biotechnology and also a PhD in Biotechnology (1990). Saelens is married and has two children. Career He worked as a Postdoc at the University of Ghent from 1990 until 2004 and he is VIB Project Leader since 2005. His current research focuses on the development and characterisation of novel influenza A and B vaccines. Together with Walter Fiers Walter Fiers (31 January 1931 in Ypres, West Flanders – 28 July 2019 in Destelbergen) was a Belgian molecular biologist. He obtained a degree of Engineer for Chemistry and Agricultural Industries at the University of Ghent in 1954, and started ... and their team, he works ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heterologous
The term heterologous has several meanings in biology. Gene expression In cell biology and protein biochemistry, heterologous expression means that a protein is experimentally put into a cell that does not normally make (i.e., express) that protein. Heterologous (meaning 'derived from a different organism') refers to the fact that often the transferred protein was initially cloned from or derived from a different cell type or a different species from the recipient. Typically the protein itself is not transferred, but instead the 'correctly edited' genetic material coding for the protein (the complementary DNA or cDNA) is added to the recipient cell. The genetic material that is transferred typically must be within a format that encourages the recipient cell to express the cDNA as a protein (i.e., it is put in an expression vector). Methods for transferring foreign genetic material into a recipient cell include transfection and transduction. The choice of recipient cell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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