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W. Richard S. Doll
Sir William Richard Shaboe Doll (28 October 1912 – 24 July 2005) was a British physician who became an epidemiologist in the mid-20th century and made important contributions to that discipline. He was a pioneer in research linking Tobacco smoking, smoking to health problems. With Ernst Wynder, Austin Bradford Hill, Bradford Hill and Evarts Ambrose Graham, Evarts Graham, he was credited with being the first to prove that smoking increased the risk of :lung cancer and :heart disease. (German studies had suggested a link as early as the 1920s but were forgotten or ignored until the 1990s.) He also carried out pioneering work on the relationship between radiation and leukaemia as well as that between asbestos and lung cancer, and alcohol (drug), alcohol and breast cancer. On 28 June 2012, he was the subject of an episode of ''The New Elizabethans'', a series broadcast on BBC Radio Four to mark the Diamond Jubilee of Elizabeth II, Diamond Jubilee of Queen Elizabeth II, dealing wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hampton, London
Hampton is a suburban area on the north bank of the River Thames, in the London Borough of Richmond upon Thames, England, and historically in the County of Middlesex. which includes Hampton Court Palace. Hampton is served by two railway stations, including one immediately south of Hampton Court Bridge in East Molesey. Hampton adjoins Bushy Park on two sides and is west of Hampton Wick and Kingston upon Thames. There are long strips of public riverside in Hampton and the Hampton Heated Open Air Pool is one of the few such swimming pools in Greater London. The riverside, on the reach above Molesey Lock, has residential islands, a park named St Albans Riverside and grand or decorative buildings including Garrick's House and the Temple to Shakespeare; also on the river is the Astoria Houseboat recording studio. Hampton Ferry provides access across the Thames to the main park of Molesey and the Thames Path National Trail. The Thames Water Hampton Water Treatment Works covers a lar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Commission On Radiological Protection
The International Commission on Radiological Protection (ICRP) is an independent, international, non-governmental organization, with the mission to protect people, animals, and the environment from the harmful effects of ionising radiation. Its recommendations form the basis of radiological protection policy, regulations, guidelines and practice worldwide. The ICRP was effectively founded in 1928 at the second International Congress of Radiology in Stockholm, Sweden but was then called the International X-ray and Radium Protection Committee (IXRPC). In 1950 it was restructured to take account of new uses of radiation outside the medical area and re-named as the ICRP. The ICRP is a sister organisation to the International Commission on Radiation Units and Measurements (ICRU). In general terms ICRU defines the units, and ICRP recommends, develops and maintains the International system of radiological protection which uses these units. Operation The ICRP is a not-for-profit organ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alcohol (drug)
Alcohol, sometimes referred to by the chemical name ''ethanol'', is a depressant, depressant drug that is the active ingredient in alcoholic drink, drinks such as beer, wine, and distilled spirits (hard liquor). It is one of the oldest and most commonly consumed recreational drugs, causing the characteristic effects of alcohol intoxication ("drunkenness"). Among other effects, alcohol produces happiness and euphoria, anxiolytic, decreased anxiety, increased sociability, sedation, impairment of cognitive, memory, motor control, motor, and sense, sensory function, and generalized depression of central nervous system (CNS) function. Ethanol is only one of several types of Alcohol (chemistry), alcohol, but it is the only type of alcohol that is found in alcoholic beverages or commonly used for recreational purposes; other alcohols such as methanol and isopropyl alcohol are significantly more toxicity, toxic. A mild, brief exposure to isopropanol, being only moderately more toxic tha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asbestos
Asbestos () is a naturally occurring fibrous silicate mineral. There are six types, all of which are composed of long and thin fibrous crystals, each fibre being composed of many microscopic "fibrils" that can be released into the atmosphere by abrasion and other processes. Inhalation of asbestos fibres can lead to various dangerous lung conditions, including mesothelioma, asbestosis, and lung cancer, so it is now notorious as a serious health and safety hazard. Archaeological studies have found evidence of asbestos being used as far back as the Stone Age to strengthen ceramic pots, but large-scale mining began at the end of the 19th century when manufacturers and builders began using asbestos for its desirable physical properties. Asbestos is an excellent electrical insulator and is highly fire-resistant, so for much of the 20th century it was very commonly used across the world as a building material, until its adverse effects on human health were more widely acknowledged ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leukaemia
Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ''leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia— acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic myelo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Journal Of Epidemiology
The ''International Journal of Epidemiology'' is a bimonthly peer-reviewed medical journal covering research in epidemiology. It is the official journal of the International Epidemiological Association and is published by Oxford University Press. The journal is a member of the Committee on Publication Ethics. The editor-in-chief is Stephen Leeder (University of Sydney). History The journal was established in 1972 by the International Epidemiological Association to facilitate communication among its members and all those engaged in research, teaching and the application of epidemiology. The first editor-in-chief, Walter W. Holland, hoped to "overcome some of the problems of publication of epidemiological work in local journals, which often tend to be unavailable to workers outside that country" and to "create an international viewpoint of health problems." Editors The following persons are or have been editors-in-chief: *1972–1977: Walter W. Holland *1978–1981: A.E. Bennett ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
:heart Disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, abnormal heart rhythms, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, and poor sleep, among other things. High blood pressure is estimated to account for approximately ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
:lung Cancer
Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor. Without treatment, tumors spread throughout the lung, damaging lung function. Eventually lung tumors metastasize, spreading to other parts of the body. Early lung cancer often has no symptoms, and can only be detected by medical imaging. As the cancer progresses, most people experience unspecific respiratory problems: coughing, shortness of breath, and/or chest pain. Other symptoms depend on the location and size of the tumor. Those suspected of having lung cancer typically undergo a series of imaging tests to determine the location and extent of any tumors. Definitive diagnosis of lung cancer requires a biopsy of the suspected tumor be examined by a patholog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evarts Ambrose Graham
Evarts Ambrose Graham (1883–1957) was an American academic, physician, and surgeon. Early years and military service Born in Chicago, Illinois to a surgeon, Dr. David Wilson Graham, and Ida Ansbach Barned Graham, Evarts attended college at Princeton University (A.B., 1904) and received his M.D. degree from Rush Medical College in 1907. Graham then trained as a surgery resident at Presbyterian Hospital in Chicago, and subsequently as a graduate student in chemistry at the University of Chicago. There, he met his wife, Helen Tredway, Ph.D. (1890-1971), a biochemist and pharmacologist. Evarts served as a Major (O4) in the U.S. Army Medical Corps from 1917 to 1919, and was initially posted to Camp Lee (now Fort Lee, Virginia). He completed revolutionary new work on surgical technique for the treatment of empyema, which had become important following the influenza pandemic of 1918. Afterwards, Dr. Graham served in France as commander of U.S. Army Evacuation Hospital 34. Career a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Austin Bradford Hill
Sir Austin Bradford Hill (8 July 1897 – 18 April 1991) was an English epidemiologist and statistician, pioneered the randomised clinical trial and, together with Richard Doll, demonstrated the connection between cigarette smoking and lung cancer. Hill is widely known for pioneering the "Bradford Hill" criteria for determining a causal association. Early life Hill was born in London, son of Sir Leonard Erskine Hill FRS, a distinguished physiologist, and Janet Alexander. He was the grandson of noted scholar George Birkbeck Hill. As a child he lived at the family home, Osborne House, Loughton, Essex; he was educated at Chigwell School, Essex. He served as a pilot in the First World War but was invalided out when he contracted tuberculosis. Two years in hospital and two years of convalescence put a medical qualification out of the question and he took a degree in economics by correspondence at London University. Career In 1922, Hill went to work for the Industry Fatigue Resea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ernst Wynder
Ernst Ludwig Wynder (April 30, 1922 – July 14, 1999) was an American epidemiology and public health researcher who studied the health effects of smoking tobacco. His and Evarts Ambrose Graham's joint publication of "Tobacco Smoking as a Possible Etiologic Factor in Bronchiogenic Carcinoma: A Study of 684 Proved Cases" appeared in the Journal of the American Medical Association. It was one of the first major scientific publications to identify smoking as a contributory cause of lung cancer. Biography Wynder was born in Herford, Westphalia in 1922 to Jewish parents (a cousin of Robert Weinberg). In 1938 his family escaped Nazi rule and fled to the United States, where Wynder enrolled at New York University. During World War II, he attained citizenship and joined the U.S. Army, where, as a German-speaker, he was assigned to a psychological warfare unit to monitor German newscasts. After the war, he attended medical school at Washington University in St. Louis. In 1950, he rece ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tobacco Smoking
Tobacco smoking is the practice of burning tobacco and ingesting the resulting smoke. The smoke may be inhaled, as is done with cigarettes, or simply released from the mouth, as is generally done with pipes and cigars. The practice is believed to have begun as early as 5000–3000 BC in Mesoamerica and South America. Tobacco was introduced to Eurasia in the late 17th century by European colonists, where it followed common trade routes. The practice encountered criticism from its first import into the Western world onwards but embedded itself in certain strata of a number of societies before becoming widespread upon the introduction of automated cigarette-rolling apparatus. Smoking is the most common method of consuming tobacco, and tobacco is the most common substance smoked. The agricultural product is often mixed with additives and then combusted. The resulting smoke is then inhaled and the active substances absorbed through the alveoli in the lungs or the oral mucosa. Many ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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