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Viviana Gradinaru
Viviana Grădinaru (born 1981) is a Romanian-American neuroscientist who is Professor of Neuroscience at the California Institute of Technology. She develops technologies for brain imaging, including optogenetics and CLARITY, to understand reward and sleep. She has been awarded the Presidential Early Career Award for Scientists and Engineers and the National Institutes of Health Director's Pioneer Award. In 2019 she was a finalist for the Blavatnik Awards for Young Scientists. In 2020 she was awarded a Vilcek Prize for Creative Promise in Biomedical Science by the Vilcek Foundation. Early life and education Gradinaru is a native of Vaslui, Romania, and grew up with her grandparents in a small village. As a child, her grandparents and the rest of her community would work together to solve local problems. As a native of Eastern Europe, Gradinaru was encouraged to study science from a young age, and took part in science olympiads. She has said that she benefitted from the many "br ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford University
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eastern Europe
Eastern Europe is a subregion of the Europe, European continent. As a largely ambiguous term, it has a wide range of geopolitical, geographical, ethnic, cultural, and socio-economic connotations. The vast majority of the region is covered by Russia, which spans roughly 40% of the continent's landmass while accounting for approximately 15% of its total population."The Balkans" , ''Global Perspectives: A Remote Sensing and World Issues Site''. Wheeling Jesuit University/Center for Educational Technologies, 1999–2002. It represents a significant part of Culture of Europe, European culture; the main socio-cultural characteristics of Eastern Europe have historically been defined by the traditions of Slavs and Greeks, as well as by the influence of Eastern Christianity as it developed through t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Body Tissue
In biology, tissue is a biological organizational level between cells and a complete organ. A tissue is an ensemble of similar cells and their extracellular matrix from the same origin that together carry out a specific function. Organs are then formed by the functional grouping together of multiple tissues. The English word "tissue" derives from the French word "tissu", the past participle of the verb tisser, "to weave". The study of tissues is known as histology or, in connection with disease, as histopathology. Xavier Bichat is considered as the "Father of Histology". Plant histology is studied in both plant anatomy and physiology. The classical tools for studying tissues are the paraffin block in which tissue is embedded and then sectioned, the histological stain, and the optical microscope. Developments in electron microscopy, immunofluorescence, and the use of frozen tissue-sections have enhanced the detail that can be observed in tissues. With these tools, the classi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood–brain Barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane, semipermeable border of endothelium, endothelial cells that prevents solutes in the circulating blood from ''non-selectively'' crossing into the extracellular fluid of the central nervous system where neurons reside. The blood–brain barrier is formed by endothelial cells of the Capillary, capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane. This system allows the passage of some small molecules by passive transport, passive diffusion, as well as the selective and active transport of various nutrients, ions, organic anions, and macromolecules such as glucose and amino acids that are crucial to neural function. The blood–brain barrier restricts the passage of pathogens, the diffusion of solutes in the blood, and Molecular mass, large or Hydrophile, hydrophilic molecules into the cerebrospinal fluid, while allowing the diffusion of Hydr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Principal Investigator
In many countries, the term principal investigator (PI) refers to the holder of an independent grant and the lead researcher for the grant project, usually in the sciences, such as a laboratory study or a clinical trial. The phrase is also often used as a synonym for "head of the laboratory" or "research group leader". While the expression is common in the sciences, it is used widely for the person or persons who make final decisions and supervise funding and expenditures on a given research project. A co-investigator (Co-I) assists the principal investigator in the management and leadership of the research project. There may be a number of co-investigators supporting a PI. Federal funding In the context of United States federal funding from agencies such as the National Institutes of Health (NIH) or the National Science Foundation (NSF), the PI is the person who takes direct responsibility for completion of a funded project, directing the research and reporting directly to the fun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Optogenetics
Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells. On the level of individual cells, light-activated enzymes and transcription factors allow precise control of biochemical signaling pathways. In systems neuroscience, the ability to control the activity of a genetically defined set of neurons has been used to understand their contribution to decision making, learning, fear memory, mating, addiction, feeding, and locomotion. In a first medical application of optogenetic technology, vision was partially restored in a blind patient. Optogenetic techniques have also been introduced to map the functional connectivity of the brain''.'' By altering the activity of genetically labelled neurons with light and using imaging and electrophysiology techniques to record the activity of other cells, researchers can identify ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quickstep
The quickstep is a light-hearted dance of the standard ballroom dances. The movement of the dance is fast and powerfully flowing and sprinkled with syncopations. The upbeat melodies that quickstep is danced to make it suitable for both formal and informal events. Quickstep was developed in the 1920s in New York City and was first danced by Black Americans. Its origins are in combination of slow foxtrot combined with the Charleston (dance), Charleston, a dance which was one of the precursors to what today is called swing dancing. History The quickstep evolved in the 1920s from a combination of the foxtrot, Charleston (dance), Charleston, Collegiate shag (dance), shag, Peabody (dance), peabody, and One-Step, one-step. The dance is English in origin and was standardized in 1927. While it evolved from the foxtrot, the quickstep now is quite separate. Unlike the modern foxtrot, the lead and follow, leader often closes his feet, and syncopated steps are regular occurrences (as was the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ballroom Dance
Ballroom dance is a set of partner dances, which are enjoyed both socially and competitively around the world, mostly because of its performance and entertainment aspects. Ballroom dancing is also widely enjoyed on stage, film, and television. ''Ballroom dance'' may refer, at its widest definition, to almost any recreational dance with a partner. However, with the emergence of dance competition (now known as Dancesport), two principal schools have emerged and the term is used more narrowly to refer to the dances recognized by those schools. * The International School, originally developed in EnglandFranks A.H. 1963. ''Social dance: a short history''. Routledge & Kegan Paul, London. and now regulated by the World Dance CouncilWDC and the World DanceSport FederationWDSF, is most prevalent in Europe. It encompasses two categories, Standard and Latin, each of which consist of five dances—International Waltz, International Tango, International Viennese Waltz, International Slow F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford Optogenetics Innovation Laboratory
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneurialism t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cold Spring Harbor Laboratory
Cold Spring Harbor Laboratory (CSHL) is a private, non-profit institution with research programs focusing on cancer, neuroscience, plant biology, genomics, and quantitative biology. It is one of 68 institutions supported by the Cancer Centers Program of the U.S. National Cancer Institute (NCI) and has been an NCI-designated Cancer Center since 1987. The Laboratory is one of a handful of institutions that played a central role in the development of molecular genetics and molecular biology. It has been home to eight scientists who have been awarded the Nobel Prize in Physiology or Medicine. CSHL is ranked among the leading basic research institutions in molecular biology and genetics with Thomson Reuters ranking it #1 in the world. CSHL was also ranked #1 in research output worldwide by ''Nature''. The Laboratory is led by Bruce Stillman, a biochemist and cancer researcher. Since its inception in 1890, the institution's campus on the North Shore of Long Island has also been ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular biology, molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
