Visible Embryo Project
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Visible Embryo Project
The Visible Embryo Project (VEP) is a multi-institutional, multidisciplinary research project originally created in the early 1990s as a collaboration between the Developmental Anatomy Center at the National Museum of Health and Medicine and the Biomedical Visualization Laboratory (BVL) at the University of Illinois at Chicago, "to develop software strategies for the development of distributed biostructural databases using cutting-edge technologies for high-performance computing and communications (HPCC), and to implement these tools in the creation of a large-scale digital archive of multidimensional data on normal and abnormal human development." This project related to BVL's other research in the areas of health informatics, educational multimedia, and biomedical imaging science. Over the following decades, the list of VEP collaborators grew to include over a dozen universities, national laboratories, and companies around the world. An early (1993) goal of the project was to ena ...
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National Museum Of Health And Medicine
The National Museum of Health and Medicine (NMHM) is a museum in Silver Spring, Maryland, near Washington, DC. The museum was founded by U.S. Army Surgeon General William A. Hammond as the Army Medical Museum (AMM) in 1862; it became the NMHM in 1989 and relocated to its present site at the Army's Forest Glen Annex in 2011. An element of the Defense Health Agency (DHA), the NMHM is a member of the National Health Sciences Consortium. History 19th century The AMM was established during the American Civil War as a center for the collection of specimens for research in military medicine and surgery. In 1862, Hammond directed medical officers in the field to collect "specimens of morbid anatomy...together with projectiles and foreign bodies removed" and to forward them to the newly founded museum for study. The AMM's first curator, John H. Brinton, visited mid-Atlantic battlefields and solicited contributions from doctors throughout the Union Army. During and after the war, AMM ...
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Lawrence Livermore National Laboratory
Lawrence Livermore National Laboratory (LLNL) is a federal research facility in Livermore, California, United States. The lab was originally established as the University of California Radiation Laboratory, Livermore Branch in 1952 in response to the detonation of the first atomic bomb by the Soviet Union during the Cold War. It later became autonomous in 1971 and was designated a national laboratory in 1981. A federally funded research and development center, Lawrence Livermore Lab is primarily funded by the U.S. Department of Energy and it is managed privately and operated by Lawrence Livermore National Security, LLC (a partnership of the University of California), Bechtel, BWX Technologies, AECOM, and Battelle Memorial Institute in affiliation with the Texas A&M University System. In 2012, the laboratory had the synthetic chemical element livermorium (element 116) named after it. Overview LLNL is self-described as a "premier research and development institution for sci ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ...
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Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ...
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Scientific Visualization
Scientific visualization ( also spelled scientific visualisation) is an interdisciplinary branch of science concerned with the visualization of scientific phenomena.Michael Friendly (2008)"Milestones in the history of thematic cartography, statistical graphics, and data visualization" It is also considered a subset of computer graphics, a branch of computer science. The purpose of scientific visualization is to graphically illustrate scientific data to enable scientists to understand, illustrate, and glean insight from their data. Research into how people read and misread various types of visualizations is helping to determine what types and features of visualizations are most understandable and effective in conveying information. History One of the earliest examples of three-dimensional scientific visualisation was Maxwell's thermodynamic surface, sculpted in clay in 1874 by James Clerk Maxwell. This prefigured modern scientific visualization techniques that use computer graph ...
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Microarray
A microarray is a multiplex lab-on-a-chip. Its purpose is to simultaneously detect the expression of thousands of genes from a sample (e.g. from a tissue). It is a two-dimensional array on a solid substrate—usually a glass slide or silicon thin-film cell—that assays (tests) large amounts of biological material using high-throughput screening miniaturized, multiplexed and parallel processing and detection methods. The concept and methodology of microarrays was first introduced and illustrated in antibody microarrays (also referred to as antibody matrix) by Tse Wen Chang in 1983 in a scientific publication and a series of patents. The "gene chip" industry started to grow significantly after the 1995 ''Science Magazine'' article by the Ron Davis and Pat Brown labs at Stanford University. With the establishment of companies, such as Affymetrix, Agilent, Applied Microarrays, Arrayjet, Illumina, and others, the technology of DNA microarrays has become the most sophisticated and ...
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Quicktime VR
QuickTime VR (also known as QTVR) is an image file format developed by Apple Inc. for QuickTime, and discontinued along with QuickTime 7. It allows the creation and viewing of VR photography, photographically captured panoramas, and the viewing of objects photographed from multiple angles. It functions as plugins for the QuickTime Player and for the QuickTime Web browser plugin. History QuickTime VR was conceived in 1991 by programmers Eric Chen and Ian Small of the Human Interface Group in the Advanced Technology Group at Apple, utilizing a Cray supercomputer to process images into panoramas. It was soon made prominent within the company by Apple's board member and former astronaut Sally Ride, who was fascinated by the demonstrated possibilities of 3D computer imagery. It was publicly launched in 1995 as part of QuickTime 2, by a dedicated group including Chen, Small, senior content engineer Ted Casey, and program manager Eric Zarakov. Apple sold the content authoring tools ...
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Johns Hopkins University
Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hemisphere. It consistently ranks among the most prestigious universities in the United States and the world. The university was named for its first benefactor, the American entrepreneur and Quaker philanthropist Johns Hopkins. Hopkins' $7 million bequest to establish the university was the largest Philanthropy, philanthropic gift in U.S. history up to that time. Daniel Coit Gilman, who was inaugurated as :Presidents of Johns Hopkins University, Johns Hopkins's first president on February 22, 1876, led the university to revolutionize higher education in the U.S. by integrating teaching and research. In 1900, Johns Hopkins became a founding member of the American Association of Universities. The university has led all Higher education in the U ...
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Armed Forces Institute Of Pathology
The Armed Forces Institute of Pathology (AFIP) (1862 – September 15, 2011) was a U.S. government institution concerned with diagnostic consultation, education, and research in the medical specialty of pathology. Overview It was founded in 1862 as the Army Medical Museum in Washington, D.C., on the grounds of the Walter Reed Army Medical Center (WRAMC). It primarily provided second opinion diagnostic consultations on pathologic specimens such as biopsies from military, veteran, and civilian medical, dental, and veterinary sources. The unique character of the AFIP rested in the expertise of its civilian and military staff of diagnostic pathologists whose daily work consisted of the study of cases that are difficult to diagnose owing to their rarity or their variation from the ordinary. The accumulation of such cases has resulted in a rich repository of lesions, numbering over three million, that have been the basis of major pathological studies. Examples are the published rep ...
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Eolas
Eolas (, meaning "Knowledge"; bacronym: "Embedded Objects Linked Across Systems") is a United States technology firm formed as a spin-off from the University of California, San Francisco (UCSF), in order to commercialize UCSF's patents for work done there by Eolas' co-founders, as part of the Visible Embryo Project. The company was founded in 1994 by Dr. Michael Doyle, Rachelle Tunik, David Martin, and Cheong Ang from the UCSF Center for Knowledge Management (CKM). The company was created at the request of UCSF, and was founded by the inventors of the university's patents. In addition to the work done while at UCSF, Dr. Doyle has led work at Eolas to create new technologies ranging from Spatial Genomics/Spatial transcriptomics, Code signing, transient-key cryptography, and blockchain to mobile AI assistants and automated audio conversation annotation. The University of California, San Francisco CKM team created an advanced early web browser that supported plugins, streaming ...
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George Mason University
George Mason University (George Mason, Mason, or GMU) is a public research university in Fairfax County, Virginia with an independent City of Fairfax, Virginia postal address in the Washington, D.C. Metropolitan Area. The university was originally founded in 1949 as a Northern Virginia regional branch of the University of Virginia. Named after Founding Father of the United States George Mason in 1959, it became an independent university in 1972. The school has since grown into the largest public university in the Commonwealth of Virginia. Mason operates four campuses in Virginia ( Fairfax, Arlington, Front Royal, and Prince William), as well as a campus in Incheon, South Korea. The flagship campus is in Fairfax. The university is classified among "R1: Doctoral Universities – Very high research activity". Two professors were awarded the Nobel Memorial Prize in Economics during their time at George Mason University: James M. Buchanan in 1986 and Vernon L. Smith in 2002. Ea ...
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Harvard
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ...
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