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Eolas
Eolas (, meaning "Knowledge"; bacronym: "Embedded Objects Linked Across Systems") is a United States technology firm formed as a spin-off from the University of California, San Francisco (UCSF), in order to commercialize UCSF's patents for work done there by Eolas' co-founders, as part of the Visible Embryo Project. The company was founded in 1994 by Dr. Michael Doyle, Rachelle Tunik, David Martin, and Cheong Ang from the UCSF Center for Knowledge Management (CKM). The company was created at the request of UCSF, and was founded by the inventors of the university's patents. In addition to the work done while at UCSF, Dr. Doyle has led work at Eolas to create new technologies ranging from Spatial Genomics/Spatial transcriptomics, Code signing, transient-key cryptography, and blockchain to mobile AI assistants and automated audio conversation annotation. The University of California, San Francisco CKM team created an advanced early web browser that supported plugins, streaming ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ViolaWWW PlotDemo
ViolaWWW is a discontinued browser, the first to support scripting and stylesheets for the World Wide Web (WWW). It was first released in 1991/1992 for Unix and acted as the recommended browser at CERN, where the WWW was invented, but eventually lost its position as most frequently used browser to Mosaic. Viola Released in 1992, Viola was the invention of Pei-Yuan Wei, a member of the eXperimental Computing Facility (XCF) at the University of California, Berkeley. Viola was a UNIX-based programming/scripting language; the acronym stood for "Visually Interactive Object-oriented Language and Application". Pei's interest in graphically based software began with HyperCard, which he first encountered in 1989. Of that, Pei said, "HyperCard was very compelling back then, you know graphically, this hyperlink thing, it was just not very global and it only worked on Mac ... and I didn't even have a Mac". Only having access to X terminals, Pei, in 1990, created the first version of Viola f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ViolaWWW
ViolaWWW is a discontinued browser, the first to support scripting and stylesheets for the World Wide Web (WWW). It was first released in 1991/1992 for Unix and acted as the recommended browser at CERN, where the WWW was invented, but eventually lost its position as most frequently used browser to Mosaic. Viola Released in 1992, Viola was the invention of Pei-Yuan Wei, a member of the eXperimental Computing Facility (XCF) at the University of California, Berkeley. Viola was a UNIX-based programming/scripting language; the acronym stood for "Visually Interactive Object-oriented Language and Application". Pei's interest in graphically based software began with HyperCard, which he first encountered in 1989. Of that, Pei said, "HyperCard was very compelling back then, you know graphically, this hyperlink thing, it was just not very global and it only worked on Mac ... and I didn't even have a Mac". Only having access to X terminals, Pei, in 1990, created the first version of Viola ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pei-Yuan Wei
Pei-Yuan Wei () is a Taiwanese-American businessman who created ViolaWWW, the first popular graphical web browser. Career Pei-Yuan Wei was born in Pingtung County, Taiwan. He graduated from Berkeley High School in 1986. He received his bachelor's degree from the University of California, Berkeley, and was a member of the student club, the eXperimental Computing Facility (XCF). In the 1990s, Wei was a founding employee of Global Network Navigator, one of the first Internet-based businesses. Later he worked for various Palm OS-related businesses. Since 2008, Perry has been living in both Taiwan and the US, and has devoted most of his time to taking care of his ill family member. Controversy Pei-Yuan Wei was at the center of a controversy over patents relating to embedded objects in a web browser, which revolves around whether his browser, ViolaWWW, had the capability to launch embedded objects, prior to the date a patent was filed by Michael David Doyle of Eolas, and the Univers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Visible Embryo Project
The Visible Embryo Project (VEP) is a multi-institutional, multidisciplinary research project originally created in the early 1990s as a collaboration between the Developmental Anatomy Center at the National Museum of Health and Medicine and the Biomedical Visualization Laboratory (BVL) at the University of Illinois at Chicago, "to develop software strategies for the development of distributed biostructural databases using cutting-edge technologies for high-performance computing and communications (HPCC), and to implement these tools in the creation of a large-scale digital archive of multidimensional data on normal and abnormal human development." This project related to BVL's other research in the areas of health informatics, educational multimedia, and biomedical imaging science. Over the following decades, the list of VEP collaborators grew to include over a dozen universities, national laboratories, and companies around the world. An early (1993) goal of the project was to ena ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spatial Transcriptomics
Spatial transcriptomics is a method for assigning cell types (identified by the mRNA readouts) to their locations in the histological sections. This method can also be used to determine subcellular localization of mRNA molecules. The term is a variation of Spatial Genomics, first described by Doyle, et al., in 2000 and then expanded upon by Ståhl et al. in a technique developed in 2016, which has since undergone a variety of improvements and modifications. The Ståhl method implies positioning individual tissue samples on the arrays of spatially barcoded reverse transcription primers able to capture mRNA with the tails. Besides tail and spatial barcode, which indicates the x and y position on the arrayed slide, the probe contains a cleavage site, amplification and sequencing handle, and unique molecular identifier. Commonly, histological samples are cut using cryotome, then fixed, stained, and put on the microarrays. After that, it undergoes enzymatic permeabilization, so tha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transient-key Cryptography
Transient-key cryptography is a form of public-key cryptography wherein keypairs are generated and assigned to brief intervals of time instead of to individuals or organizations, and the blocks of cryptographic data are chained through time. In a transient-key system, private keys are used briefly and then destroyed, which is why it is sometimes nicknamed “disposable crypto.” Data encrypted with a private key associated with a specific time interval can be irrefutably linked to that interval, making transient-key cryptography particularly useful for digital trusted timestamping. Transient-key cryptography was invented in 1997 by Dr. Michael Doyle of Eolas, and has been adopted in the ANSI ASC X9.95 Standard for trusted timestamps. Public-key vs. transient-key cryptography Both public-key and transient-key systems can be used to generate digital signatures that assert that a given piece of data has not changed since it was signed. But the similarities end there. In a traditional ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Code Signing
Code signing is the process of digitally signing executables and scripts to confirm the software author and guarantee that the code has not been altered or corrupted since it was signed. The process employs the use of a cryptographic hash to validate authenticity and integrity. Code signing was invented in 1995 by Michael Doyle, as part of the Eolas WebWish browser plug-in, which enabled the use of public-key cryptography to sign downloadable Web app program code using a secret key, so the plug-in code interpreter could then use the corresponding public key to authenticate the code before allowing it access to the code interpreter’s APIs. Code signing can provide several valuable features. The most common use of code signing is to provide security when deploying; in some programming languages, it can also be used to help prevent namespace conflicts. Almost every code signing implementation will provide some sort of digital signature mechanism to verify the identity of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mosaic (web Browser)
NCSA Mosaic is a discontinued web browser, one of the first to be widely available. It was instrumental in popularizing the World Wide Web and the general Internet by integrating multimedia such as text and graphics. It was named for its support of multiple Internet protocols, such as Hypertext Transfer Protocol, File Transfer Protocol, Network News Transfer Protocol, and Gopher. Its intuitive interface, reliability, personal computer support, and simple installation all contributed to its popularity within the web. Mosaic is the first browser to display images inline with text instead of in a separate window. It is often described as the first graphical web browser, though it was preceded by WorldWideWeb, the lesser-known Erwise, and ViolaWWW. Mosaic was developed at the National Center for Supercomputing Applications (NCSA) at the University of Illinois at Urbana–Champaign beginning in late 1992. NCSA released it in 1993, and officially discontinued development and support on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
US Court Of Appeals For The Federal Circuit
The United States Court of Appeals for the Federal Circuit (in case citations, Fed. Cir. or C.A.F.C.) is a United States court of appeals that has special appellate jurisdiction over certain types of specialized cases in the U.S. federal court system. It has exclusive appellate jurisdiction over all U.S. federal cases involving patents, trademarks, government contracts, veterans' benefits, public safety officers' benefits, federal employees' benefits, and various other categories. Unlike other federal courts, the Federal Circuit has no jurisdiction over cases involving criminal, bankruptcy, immigration, or U.S. state law. Headquartered in Washington, D.C., the Federal Circuit was created in 1982 with passage of the Federal Courts Improvement Act, which merged the United States Court of Customs and Patent Appeals and the appellate division of the United States Court of Claims, making the judges of the former courts into circuit judges. The court occupies the Howard T. Markey Na ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
JPMorgan Chase
JPMorgan Chase & Co. is an American multinational investment bank and financial services holding company headquartered in New York City and incorporated in Delaware. As of 2022, JPMorgan Chase is the largest bank in the United States, the world's largest bank by market capitalization, and the fifth largest bank in the world in terms of total assets, with total assets of US$3.774 trillion. Additionally, JPMorgan Chase is ranked 24th on the Fortune 500 list of the largest United States corporations by total revenue. It is considered a systemically important bank by the Financial Stability Board. As a " Bulge Bracket" bank, it is a major provider of various investment banking and financial services. It is one of America's Big Four banks, along with Bank of America, Citigroup, and Wells Fargo. JPMorgan Chase is considered to be a universal bank and a custodian bank. The J.P. Morgan brand is used by the investment banking, asset management, private banking, wealth man ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oracle Corporation
Oracle Corporation is an American multinational computer technology corporation headquartered in Austin, Texas. In 2020, Oracle was the third-largest software company in the world by revenue and market capitalization. The company sells database software and technology (particularly its own brands), cloud engineered systems, and enterprise software products, such as enterprise resource planning (ERP) software, human capital management (HCM) software, customer relationship management (CRM) software (also known as customer experience), enterprise performance management (EPM) software, and supply chain management (SCM) software. History Larry Ellison co-founded Oracle Corporation in 1977 with Bob Miner and Ed Oates under the name Software Development Laboratories (SDL). Ellison took inspiration from the 1970 paper written by Edgar F. Codd on relational database management systems ( RDBMS) named "A Relational Model of Data for Large Shared Data Banks." He heard about the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bay Area
The San Francisco Bay Area, often referred to as simply the Bay Area, is a populous region surrounding the San Francisco, San Pablo, and Suisun Bay estuaries in Northern California. The Bay Area is defined by the Association of Bay Area Governments to include the nine counties that border the aforementioned estuaries: Alameda, Contra Costa, Marin, Napa, San Mateo, Santa Clara, Solano, Sonoma, and San Francisco. Other definitions may be either smaller or larger, and may include neighboring counties that do not border the bay such as Santa Cruz and San Benito (more often included in the Central Coast regions); or San Joaquin, Merced, and Stanislaus (more often included in the Central Valley). The core cities of the Bay Area are San Francisco, San Jose, and Oakland. Home to approximately 7.76 million people, Northern California's nine-county Bay Area contains many cities, towns, airports, and associated regional, state, and national parks, connected by a complex ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
