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Viral Fossil
Paleovirology is the study of viruses that existed in the past but are now extinct. In general, viruses cannot leave behind physical fossils, therefore indirect evidence is used to reconstruct the past. For example, viruses can cause evolution of their hosts, and the signatures of that evolution can be found and interpreted in the present day. Also, some viral genetic fragments which were integrated into germline cells of an ancient organism have been passed down to our time as viral fossils, or endogenous viral elements (EVEs). EVEs that originate from the integration of retroviruses are known as endogenous retroviruses, or ERVs, and most viral fossils are ERVs. They may preserve genetic code from millions of years ago, hence the "fossil" terminology, although no one has detected a virus in mineral fossils. The most surprising viral fossils originate from non-retroviral DNA and RNA viruses. Terminology Although there is no formal classification system for EVEs, they are categoris ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PLOS Biology
''PLOS Biology'' is a monthly peer-reviewed scientific journal covering all aspects of biology. Publication began on October 13, 2003. It is the first journal published by the Public Library of Science. The editor-in-chief is Nonia Pariente. In addition to research articles, the journal publishes magazine content aimed to be accessible to a broad audience. Article types in this section are essays, "unsolved mysteries", editorials, and synopses. Abstracting and indexing The journal is abstracted and indexed in: *Biological Abstracts *BIOSIS Previews *''Current Contents''/Agriculture, Biology & Environmental Sciences *''Current Contents''/Life Sciences *Chemical Abstracts Service * Embase *''Index Medicus''/MEDLINE/PubMed *Science Citation Index *Scopus *''The Zoological Record'' According to ''Journal Citation Reports'', the journal had a 2019 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clariv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pithovirus
''Pithovirus'', first described in a 2014 paper, is a genus of giant virus known from two species, ''Pithovirus sibericum'', which infects amoebas and ''Pithovirus massiliensis''. It is a double-stranded DNA virus, and is a member of the nucleocytoplasmic large DNA viruses clade. The 2014 discovery was made when a viable specimen was found in a 30,000-year-old ice core harvested from permafrost in Siberia, Russia. Description The genus name ''Pithovirus'', a reference to large storage containers of ancient Greece known as pithoi, was chosen to describe the new species. A specimen of ''Pithovirus'' measures approximately 1.5 μm (1500 nm) in length and 0.5 μm (500 nm) in diameter, making it the largest virus yet found. It is 50% larger in size than the ''Pandoraviridae'', the previous largest-known viruses, and is larger than '' Ostreococcus'', the smallest eukaryotic cell, although ''Pandoravirus'' has the largest viral genome, containing 1.9 to 2.5 megabases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paleogenetics
Paleogenetics is the study of the past through the examination of preserved genetic material from the remains of ancient organisms. Emile Zuckerkandl and Linus Pauling introduced the term in 1963, long before the sequencing of DNA, in reference to the possible reconstruction of the corresponding polypeptide sequences of past organisms. The first sequence of ancient DNA, isolated from a museum specimen of the extinct quagga, was published in 1984 by a team led by Allan Wilson. Paleogeneticists do not recreate actual organisms, but piece together ancient DNA sequences using various analytical methods. Fossils are "the only direct witnesses of extinct species and of evolutionary events" and finding DNA within those fossils exposes tremendously more information about these species, potentially their entire physiology and anatomy. The most ancient DNA sequence to date was reported in February 2021, from the tooth of a Siberian mammoth frozen for over a million years. Applications Ev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paleobiology
Paleobiology (or palaeobiology) is an interdisciplinary field that combines the methods and findings found in both the earth sciences and the life sciences. Paleobiology is not to be confused with geobiology, which focuses more on the interactions between the biosphere and the physical Earth. Paleobiological research uses biological field research of current biota and of fossils millions of years old to answer questions about the molecular evolution and the evolutionary history of life. In this scientific quest, macrofossils, microfossils and trace fossils are typically analyzed. However, the 21st-century biochemical analysis of DNA and RNA samples offers much promise, as does the biometric construction of phylogenetic trees. An investigator in this field is known as a paleobiologist. Important research areas *Paleobotany applies the principles and methods of paleobiology to flora, especially green land plants, but also including the fungi and seaweeds (algae). See also myc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Micropaleontology
Micropaleontology (American spelling; spelled micropalaeontology in European usage) is the branch of paleontology (palaeontology) that studies microfossils, or fossils that require the use of a microscope to see the organism, its morphology and its characteristic details. Microfossils Microfossils are fossils that are generally between 0.001mm and 1 mm in size, the study of which requires the use of light or electron microscopy. Fossils which can be studied by the naked eye or low-powered magnification, such as a hand lens, are referred to as macrofossils. For example, some colonial organisms, such as Bryozoa (especially the Cheilostomata) have relatively large colonies, but are classified by fine skeletal details of the small individuals of the colony. In another example, many fossil genera of Foraminifera, which are protists are known from shells (called "tests") that were as big as coins, such as the genus '' Nummulites''. Microfossils are a common feature of the g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Invertebrate Iridescent Virus 31
''Invertebrate iridescent virus 31'' (IIV-31), also known informally as isopod iridovirus, is a species of invertebrate iridescent virus in the genus ''Iridovirus''. Oniscidea (commonly known by a variety of names including ''woodlouse'', ''pillbug'', ''slater'', ''rolly-polly'', ''potato bug'', et al.) serve as hosts. Infection is associated with decreased responsiveness in the host, increased mortality, and most strikingly, the emergence of an iridescent blue or bluish-purple colour due to the reflection of light off a paracrystalline arrangement of virions within the tissues. Taxonomy In earlier centuries, blue individuals of otherwise drab oniscidean species had been discovered. They were sometimes interpreted to be new subspecies and were described as such: ''Ligidium hypnorum coeruleum'' Lereboullet 1843 and ''L. hypnorum amethystinum'' Schöbl 1861 (in reference to cerulean and amethyst, respectively). In 1980, the first research was published showing that the phenomeno ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insertional Mutagenesis
In molecular biology, insertional mutagenesis is the creation of mutations of DNA by addition of one or more base pairs. Such insertional mutations can occur naturally, mediated by viruses or transposons, or can be artificially created for research purposes in the lab. Signature tagged mutagenesis This is a technique used to study the function of genes. A transposon such as the P element of ''Drosophila melanogaster'' is allowed to integrate at random locations in the genome of the organism being studied. Mutants generated by this method are then screened for any unusual phenotypes. If such a phenotype is found then it can be assumed that the insertion has caused the gene relating to the usual phenotype to be inactivated. Because the sequence of the transposon is known, the gene can be identified, either by sequencing the whole genome and searching for the sequence, or using the polymerase chain reaction to amplify specifically that gene. Virus insertional mutagenesis Beca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It remains the world's largest collaborative biological project. Planning started after the idea was picked up in 1984 by the US government, the project formally launched in 1990, and was declared essentially complete on April 14, 2003, but included only about 85% of the genome. Level "complete genome" was achieved in May 2021, with a remaining only 0.3% bases covered by potential issues. The final gapless assembly was finished in January 2022. Funding came from the United States government through the National Institutes of Health (NIH) as well as numerous other groups from around the world. A parallel project was conducted outside the government by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ancient DNA
Ancient DNA (aDNA) is DNA isolated from ancient specimens. Due to degradation processes (including cross-linking, deamination and fragmentation) ancient DNA is more degraded in comparison with contemporary genetic material. Even under the best preservation conditions, there is an upper boundary of 0.4–1.5 million years for a sample to contain sufficient DNA for sequencing technologies. The oldest sample ever sequenced is estimated to be 1.65 million years old. Genetic material has been recovered from paleo/archaeological and historical skeletal material, mummified tissues, archival collections of non-frozen medical specimens, preserved plant remains, ice and from permafrost cores, marine and lake sediments and excavation dirt. On 7 December 2022, ''The New York Times'' reported that two-million year old genetic material was found in Greenland, and is currently considered the oldest DNA discovered so far. History of ancient DNA studies 1980s The first study of what would ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Siberia
Siberia ( ; rus, Сибирь, r=Sibir', p=sʲɪˈbʲirʲ, a=Ru-Сибирь.ogg) is an extensive geographical region, constituting all of North Asia, from the Ural Mountains in the west to the Pacific Ocean in the east. It has been a part of Russia since the latter half of the 16th century, after the Russians conquered lands east of the Ural Mountains. Siberia is vast and sparsely populated, covering an area of over , but home to merely one-fifth of Russia's population. Novosibirsk, Krasnoyarsk and Omsk are the largest cities in the region. Because Siberia is a geographic and historic region and not a political entity, there is no single precise definition of its territorial borders. Traditionally, Siberia extends eastwards from the Ural Mountains to the Pacific Ocean, and includes most of the drainage basin of the Arctic Ocean. The river Yenisey divides Siberia into two parts, Western and Eastern. Siberia stretches southwards from the Arctic Ocean to the hills of north-ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Permafrost
Permafrost is ground that continuously remains below 0 °C (32 °F) for two or more years, located on land or under the ocean. Most common in the Northern Hemisphere, around 15% of the Northern Hemisphere or 11% of the global surface is underlain by permafrost, with the total area of around 18 million km2. This includes substantial areas of Alaska, Greenland, Canada and Siberia. It can also be located on mountaintops in the Southern Hemisphere and beneath ice-free areas in the Antarctic. Permafrost does not have to be the first layer that is on the ground. It can be from an inch to several miles deep under the Earth's surface. It frequently occurs in ground ice, but it can also be present in non-porous bedrock. Permafrost is formed from ice holding various types of soil, sand, and rock in combination. Permafrost contains large amounts of biomass and decomposed biomass that has been stored as methane and carbon dioxide, making tundra soil a carbon sink. As global war ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
