Vincent's Powders
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Vincent's Powders
Vincent Chemical Company was an Australian business noted for manufacture of a popular compound analgesic "Vincent's APC" History Dr. Harry John Clayton (ca.1887 – 31 October 1928) of Macquarie Street and medical superintendent of the Royal Prince Alfred Hospital, Sydney, took the headache remedy then in general use, composed of phenacetin and caffeine, and by experimenting with the addition of aspirin, arrived at what became the standard formulation known as A.P.C. powder, or in the Royal Prince Alfred Hospital Pharmacopæia for 1918 as ''Pulvis Analgesicus''. In 1919, at the insistence of his wife, Clayton founded a partnership consisting of Mrs Clayton, E. W. Wills, C. K. Probert (dispenser at the Royal Prince Alfred Hospital), and J. A. Vincent (1890 – 12 June 1933), who had been assistant dispenser at the hospital, and was at that time a pharmacist with a business at Five Dock. Clayton chose the names "Vincent Chemical Company" and "Vincent's APC" to distance himself, as ...
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Compound Analgesic
Compound analgesics are those with multiple active ingredients; they include many of the stronger prescription analgesics. Active ingredients that have been commonly used in compound analgesics include: * aspirin or ibuprofen * caffeine * codeine or oxycodone * paracetamol (acetaminophen) * phenacetin There is evidence that a compound of two analgesics with different mechanism of action can have an increased painkilling effect over the sum of the effect of each individual analgesic. Several such formulations have disappeared from over-the-counter status in drug store aisles and other retail outlets. One example is APC (aspirin, phenacetin, and caffeine) compound tablets common from the 1940s to 1983; because of harmful side effects of phenacetin, Anacin in the U.S. was reformulated to eliminate it; while Vincent's APC is no longer sold. Some others have been judged to contribute too often to substance abuse. Another example is Bex, a once popular Australian compound analgesic wh ...
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Newcastle Morning Herald And Miners' Advocate
The ''Newcastle Herald'' (formerly branded as ''The Herald'') is a local tabloid newspaper published daily, Monday to Saturday, in Newcastle, New South Wales, Australia. It is the only local newspaper that serves the greater Hunter Region and Central Coast region six days a week. It is owned by Australian Community Media. Overview The ''Newcastle Herald'' is the Hunter's largest local media organisation, and enjoys a long affinity and reader involvement with the region's residents. It is also well read in Sydney (with readership figures showing a 20% increase in Sydney readership on Saturdays) and interstate, and is usually seen as an accurate record of business and local data for those looking to relocate to the region. The paper features the only classifieds section published six days a week across the region. The ''Newcastle Herald'' employs more than 310 full-time staff, and injects $17 million into the local economy each year. History The ''Newcastle Herald'' had it ...
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Manufacturing Companies Based In Sydney
Manufacturing is the creation or production of goods with the help of equipment, labor, machines, tools, and chemical or biological processing or formulation. It is the essence of secondary sector of the economy. The term may refer to a range of human activity, from handicraft to high-tech, but it is most commonly applied to industrial design, in which raw materials from the primary sector are transformed into finished goods on a large scale. Such goods may be sold to other manufacturers for the production of other more complex products (such as aircraft, household appliances, furniture, sports equipment or automobiles), or distributed via the tertiary industry to end users and consumers (usually through wholesalers, who in turn sell to retailers, who then sell them to individual customers). Manufacturing engineering is the field of engineering that designs and optimizes the manufacturing process, or the steps through which raw materials are transformed into a final product. ...
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Pharmaceutical Companies Of Australia
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell therapies). Other ...
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Bex (compound Analgesic)
Bex was a strong compound analgesic which was popular in Australia for much of the 20th century. It came in the form of APC (aspirin– phenacetin–caffeine) tablets or powder, containing 42% aspirin and 42% phenacetin plus caffeine. Bex was a product of Beckers Pty Ltd, originally based at Pym Street, Dudley Park, South Australia, but which relocated to Sydney in the 1960s. It was advertised with the phrase, "Stressful Day? What you need is a cup of tea, a Bex and a good lie down".. Bex powders, as well as other APC products such as Vincent's, were particularly seen as the housewife's drug of choice in the 1950s and 1960s. However, it became recognised that these medications were addictive, and Priscilla Kincaid-Smith found that the large doses of phenacetin ingested by habitual users were responsible for widespread kidney disease. The phenacetin was removed from Bex in 1975. Bex has also been linked to kidney cancer. In popular culture ''A Cup of Tea, a Bex and a G ...
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Paracetamol
Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior to ibuprofen in that respect, and the benefits of its use for fever are unclear. Paracetamol may relieve pain in acute mild migraine but only slightly in episodic tension headache. However, the aspirin/paracetamol/caffeine combination helps with both conditions where the pain is mild and is recommended as a first-line treatment for them. Paracetamol is effective for post-surgical pain, but it is inferior to ibuprofen. The paracetamol/ibuprofen combination provides further increase in potency and is superior to either drug alone. The pain relief paracetamol provides in osteoarthritis is small and clinically insignificant. The evidence in its favor for the use in low back pain, cancer pain, and neuropathic pain is insufficient. In the sho ...
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Priscilla Kincaid-Smith
Priscilla Sheath Kincaid-Smith, Mrs. Fairley, AC, CBE (30 November 1926 – 18 July 2015), was an Australia-based South African physician and researcher, specializing in nephrology. She was a past President of the Royal Australasian College of Physicians (1986-1988; first woman Councillor in 1976), World Medical Association and International Society of Nephrology (1972–75). Early life and education Priscilla Sheath Kincaid-Smith was born in Johannesburg, 30 November 1926, and studied medical science at the University of the Witwatersrand in there. She earned her BSc (Hons) in 1946 and her BMBS (Bachelor of Medicine, Bachelor of Surgery) in 1950. She was awarded a DSc by the University of the Witwatersrand in 1979. Career From 1951–53, she worked at Baragwanath Hospital in Johannesburg, holding resident positions in Medicine and Surgery and Registrar in Medicine.
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Analgesic Nephropathy
Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, bucetin, phenacetin, and paracetamol. The term usually refers to damage induced by excessive use of combinations of these medications, especially combinations that include phenacetin. It may also be used to describe kidney injury from any single analgesic medication. The specific kidney injuries induced by analgesics are renal papillary necrosis and chronic interstitial nephritis. They appear to result from decreased blood flow to the kidney, rapid consumption of antioxidants, and subsequent oxidative damage to the kidney. This kidney damage may lead to progressive chronic kidney failure, abnormal urinalysis results, high blood pressure, and anemia. A small proportion of individuals with analgesic nephropathy may develop end-stage kidney disease. Analgesic nephropathy was once a common cause of kidney injury and end-stage kidney disease in parts of Europe, Australia, and the Uni ...
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Salicylamide
Salicylamide (''o''-hydroxybenzamide or amide of salicyl) is a non-prescription drug with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid. It was also an ingredient in the over-the-counter pain remedy BC Powder but was removed from the formulation in 2009, and Excedrin used the ingredient from 1960 to 1980 in conjunction with aspirin, acetaminophen, and caffeine. It was used in later formulations of Vincent's powders in Australia as a substitute for phenacetin. Derivatives Derivatives of salicylamide include ethenzamide, labetalol, medroxalol, lopirin, otilonium, oxyclozanide, salicylanilide, niclosamide, and raclopride. See also * 4-Aminosalicylic acid *Mesalazine *Salsalate Salsalate is a medication that belongs to the salicylate and nonsteroidal anti-inflammatory drug (NSAID) classes. Salsalate is the gener ...
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Haberfield, New South Wales
Haberfield is a suburb in the Inner West of Sydney, in the state of New South Wales, Australia. Haberfield is located 6.5 kilometres west of the Sydney central business district in the Local government in Australia, local government area of the Inner West Council. Haberfield sits south of Iron Cove, New South Wales, Iron Cove, which is part of Port Jackson, Sydney Harbour. It is bounded to the east by the Hawthorne Canal, to the northwest by the Iron Cove Creek canal and to the southwest by Parramatta Road. Its main road is Ramsay Street and the point of land that faces Iron Cove, Dobroyd Point, New South Wales, Dobroyd Point, is a historical locality of Sydney. Haberfield was dubbed "the garden suburb" in the early 20th century and retains its well-kept parks, tree-lined streets and fine Federation-era houses with immaculate gardens. The entire suburb is heritage-listed. It is also known for its Italian culture. History Haberfield was named by early landholder Richard Stant ...
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The Sydney Morning Herald
''The Sydney Morning Herald'' (''SMH'') is a daily compact newspaper published in Sydney, New South Wales, Australia, and owned by Nine. Founded in 1831 as the ''Sydney Herald'', the ''Herald'' is the oldest continuously published newspaper in Australia and "the most widely-read masthead in the country." The newspaper is published in compact print form from Monday to Saturday as ''The Sydney Morning Herald'' and on Sunday as its sister newspaper, '' The Sun-Herald'' and digitally as an online site and app, seven days a week. It is considered a newspaper of record for Australia. The print edition of ''The Sydney Morning Herald'' is available for purchase from many retail outlets throughout the Sydney metropolitan area, most parts of regional New South Wales, the Australian Capital Territory and South East Queensland. Overview ''The Sydney Morning Herald'' publishes a variety of supplements, including the magazines ''Good Weekend'' (included in the Saturday edition of ''Th ...
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The Australian Women's Weekly
''The Australian Women's Weekly'', sometimes known as simply ''The Weekly'', is an Australian monthly women's magazine published by Mercury Capital in Sydney. For many years it was the number one magazine in Australia before being outsold by the Australian edition of '' Better Homes and Gardens'' in 2014. , ''The Weekly'' has overtaken '' Better Homes and Gardens'' again, coming out on top as Australia's most read magazine. The magazine invested in the 2020 film '' I Am Woman'' about Helen Reddy, singer, feminist icon and activist. Editor-in-chief Nicole Byers told Film Ink "Helen’s story of adversity and triumph is nothing short of inspirational. ''The Weekly'' has been telling stories of iconic Australian women for more than 80 years and we're delighted to be supporting the film production". History and profile The magazine was started in 1933 by Frank Packer and Ted Theodore as a weekly publication. The first editor was George Warnecke and the initial dummy was laid out b ...
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