Victor Dubowitz
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Victor Dubowitz
Victor Dubowitz, FRCP, Hon FRCPCH (born 6 August 1931) is a British neurologist and professor emeritus at Imperial College London. He is principally known along with his wife Lilly Dubowitz for developing two clinical tests, the Dubowitz Score to estimate gestational age and the other for the systematic neurological examination of the newborn. Life Dubowitz is the son of Charley Dubowitz and Olga née Schattel. He was educated in Beaufort West Central High School in South Africa. Dubowitz graduated Doctor of Medicine from the University of Cape Town in 1954, and moved to the United Kingdom in April 1954 to gain some clinical experience, and culture and theatre. Dubowitz planned to return to South Africa after 18 months and return to general practice there, but never did, as he encountered Sir Francis Fraser at the Royal Postgraduate Medical School who directed him into a position at University Hospital Lewisham working as an ophthalmology locum. He later took another locum posi ...
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Beaufort West
Beaufort West (Afrikaans: ''Beaufort-Wes''; Xhosa: ''eBhofolo'') is a town in the Western Cape province in South Africa. It is the largest town in the arid Great Karoo region, and is known as the "Capital of the Karoo". It forms part of the Beaufort West Local Municipality, with 34,085 inhabitants in 2011. It is the centre of an agricultural district based mainly on sheep farming, and is a significant town and logistical support hub on the N1 national road. Next door to Beaufort West is the Karoo National Park. Important Permian era fossils have been found in the area to the west of the town. Initially found by David Baird, son of the local magistrate in 1827. The old Town Hall and the Dutch Reformed Church have been declared national monuments. History Beaufort West was the first town to be established in the central Karoo. The town was founded in 1818 and initially named ''Beaufort'' after Henry Somerset, 5th Duke of Beaufort, who was the father of Lord Charles Henry Somerset ...
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Ophthalmology
Ophthalmology ( ) is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a medical degree, a doctor specialising in ophthalmology must pursue additional postgraduate residency training specific to that field. This may include a one-year integrated internship that involves more general medical training in other fields such as internal medicine or general surgery. Following residency, additional specialty training (or fellowship) may be sought in a particular aspect of eye pathology. Ophthalmologists prescribe medications to treat eye diseases, implement laser therapy, and perform surgery when needed. Ophthalmologists provide both primary and specialty eye care - medical and surgical. Most ophthalmologists participate in academic research on eye diseases at some point in their training and many include research as part ...
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University Of Sheffield
, mottoeng = To discover the causes of things , established = – University of SheffieldPredecessor institutions: – Sheffield Medical School – Firth College – Sheffield Technical School – University College of Sheffield , type = Public research university , academic_staff = 5,670 (2020) - including academic atypical staff , administrative_staff = , chancellor = Lady Justice Rafferty , vice_chancellor = Koen Lamberts , students = () , undergrad = () , postgrad = () , endowment = £46.7 million (2021) , budget = £741.0 million (2020–21) , city = Sheffield , state = South Yorkshire , country = England , coor = , campus = Urban , colours = Black & gold , affiliations = Russell Group WUN ACUN8 Group White Rose Sutton 30EQUISAMBAUniversities UK , website = , logo = The University of Sheffield (informally Sheffield University or TUOS) is a public research university in Sheffield, South Yorkshire, England. Its history traces back to the f ...
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Muscle Biopsy
In medicine, a muscle biopsy is a procedure in which a piece of muscle tissue is removed from an organism and examined microscopically. A muscle biopsy can lead to the discovery of problems with the nervous system, connective tissue, vascular system, or musculoskeletal system. Indications In humans with weakness and low muscle tone, a muscle biopsy can help distinguish between myopathies (where the pathology is in the muscle tissue itself) and neuropathies (where the pathology is at the nerves innervating those muscles). Muscle biopsies can also help to distinguish among various types of myopathies, by microscopic analysis for differing characteristics when exposed to a variety of chemical reactions and stains. However, in some cases the muscle biopsy alone is inadequate to distinguish between certain myopathies. For example, a muscle biopsy showing the nucleus pathologically located in the center of the muscle cell would indicate "centronuclear myopathy", but research has shown ...
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National Hospital For Neurology And Neurosurgery
The National Hospital for Neurology and Neurosurgery (informally the National Hospital or Queen Square) is a neurological hospital in Queen Square, London. It is part of the University College London Hospitals NHS Foundation Trust. It was the first hospital to be established in England dedicated exclusively to treating the diseases of the nervous system. It is closely associated with University College London (UCL) and in partnership with the UCL Institute of Neurology, which occupies the same site, is a major centre for neuroscience research. History The hospital was founded by Johanna Chandler as the National Hospital for the Paralysed and Epileptic at Queen Square in 1859. The hospital was completely rebuilt in the early 1880s: the East Wing was re-opened by Princess Helena in 1881 and the West Wing was re-opened by the Prince of Wales in 1885. In 1904, it adopted the name National Hospital for the Relief and Cure of the Paralysed and Epileptic. The hospital served as a s ...
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Clinical Pathology
Clinical pathology is a medical specialty that is concerned with the diagnosis of disease based on the laboratory analysis of bodily fluids, such as blood, urine, and tissue homogenates or extracts using the tools of chemistry, microbiology, hematology, molecular pathology, and Immunohaematology. This specialty requires a medical residency. Clinical pathology is a term used in the US, UK, Ireland, many Commonwealth countries, Portugal, Brazil, Italy, Japan, and Peru; countries using the equivalent in the home language of "laboratory medicine" include Austria, Germany, Romania, Poland and other Eastern European countries; other terms are "clinical analysis" (Spain) and "clinical/medical biology (France, Belgium, Netherlands, North and West Africa). Licensing and subspecialities The American Board of Pathology certifies clinical pathologists, and recognizes the following secondary specialties of clinical pathology: * Chemical pathology, also called clinical chemistry * Hema ...
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Muscular Dystrophy
Muscular dystrophies (MD) are a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time. The disorders differ as to which muscles are primarily affected, the degree of weakness, how fast they worsen, and when symptoms begin. Some types are also associated with problems in other organs. Over 30 different disorders are classified as muscular dystrophies. Of those, Duchenne muscular dystrophy (DMD) accounts for approximately 50% of cases and affects males beginning around the age of four. Other relatively common muscular dystrophies include Becker muscular dystrophy, facioscapulohumeral muscular dystrophy, and myotonic dystrophy, whereas limb–girdle muscular dystrophy and congenital muscular dystrophy are themselves groups of several – usually ultrarare – genetic disorders. Muscular dystrophies are caused by mutations in genes, usually those involved in making muscle proteins. ...
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Queen Mary's Hospital, Roehampton
Queen Mary's Hospital, formerly Queen Mary's Convalescent Auxiliary Hospitals, is a community hospital in Roehampton in the London Borough of Wandsworth. It is run by St George's University Hospitals NHS Foundation Trust. History The hospital was founded in 1915, primarily by Mary Eleanor Gwynne-Holford as a military hospital to provide care for wounded soldiers. It was initially based at Roehampton House specialising in the care of amputees and soon became a world-renowned limb fitting and amputee rehabilitation centre. A fully equipped hospital was built on site in the early 1920s, a plastic and oral surgery unit developed by Sir Harold Gillies moved onto the site in 1925 and a Tropical Diseases unit was established for former prisoners of war in 1945. The hospital joined the National Health Service late (in 1961). Following discovery of significant asbestos, the original site was left in 1983. The Douglas Bader Unit (named after double-amputee RAF pilot Sir Douglas Bader) ...
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Great Ormond Street Hospital For Children
Great Ormond Street Hospital (informally GOSH or Great Ormond Street, formerly the Hospital for Sick Children) is a children's hospital located in the Bloomsbury area of the London Borough of Camden, and a part of Great Ormond Street Hospital for Children NHS Foundation Trust. The hospital is the largest centre for child heart surgery in the UK and one of the largest centres for heart transplantation in the world. In 1962 they developed the first heart and lung bypass machine for children. With children's book author Roald Dahl, they developed an improved shunt valve for children with hydrocephalus, and non-invasive (percutaneous) heart valve replacements. They did the first UK clinical trials of the rubella vaccine, and the first bone marrow transplant and gene therapy for severe combined immunodeficiency.Breakthroughs It is closely associated with University College London (UCL) and in partnership with the UCL Great Ormond Street Institute of Child Health, which is adjace ...
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Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death. It may also appear later in life and then have a milder course of the disease. The common feature is progressive weakness of voluntary muscles, with arm, leg and respiratory muscles being affected first. Associated problems may include poor head control, difficulties swallowing, scoliosis, and joint contractures. The age of onset and the severity of symptoms form the basis of the traditional classification of spinal muscular atrophy into a number of types. Spinal muscular atrophy is due to an abnormality (mutation) in the ''SMN1'' gene which encodes SMN, a protein necessary for survival of motor neurons. Loss of these neurons in the spinal cord prevents signalling between the brain and skeletal muscles. Another g ...
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