Valter Longo
   HOME
*





Valter Longo
Valter D. Longo (born October 9, 1967) is an Italian-American biogerontologist and cell biologist known for his studies on the role of fasting and nutrient response genes on cellular protection aging and diseases and for proposing that longevity is regulated by similar genes and mechanisms in many eukaryotes. He is currently a professor at the USC Davis School of Gerontology with a joint appointment in the department of Biological Sciences as well as serving as the director of the USC Longevity Institute. Early life and education Longo was born in Genoa, Italy to Calabrian parents. He moved to Chicago in the United States as a teenager in order to become a professional rock guitarist, and lived with extended relatives. While there, he observed that his relatives in the United States, who were eating diets rich in fat, meat and sugar, were suffering from cardiovascular disease, which was rare among his family living in Italy. He joined the United States Army Reserve as a way ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Genoa, Italy
Genoa ( ; it, Genova ; lij, Zêna ). is the capital of the Regions of Italy, Italian region of Liguria and the List of cities in Italy, sixth-largest city in Italy. In 2015, 594,733 people lived within the city's administrative limits. As of the 2011 Italian census, the Province of Genoa, which in 2015 became the Metropolitan City of Genoa, had 855,834 resident persons. Over 1.5 million people live in the wider metropolitan area stretching along the Italian Riviera. On the Gulf of Genoa in the Ligurian Sea, Genoa has historically been one of the most important ports on the Mediterranean Sea, Mediterranean: it is currently the busiest in Italy and in the Mediterranean Sea and twelfth-busiest in the European Union. Genoa was the capital of Republic of Genoa, one of the most powerful maritime republics for over seven centuries, from the 11th century to 1797. Particularly from the 12th century to the 15th century, the city played a leading role in the commercial trade in Euro ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Recruit Training
Military recruit training, commonly known as basic training or boot camp, refers to the initial instruction of new military personnel. It is a physically and psychologically intensive process, which resocializes its subjects for the unique demands of military employment. Major characteristics Initial military training is an intensive residential programme commonly lasting several weeks or months, which aims to induct newly recruited military personnel into the social norms and essential tasks of the armed forces. Common features include foot drill, inspections, physical training, weapons training, and a graduation parade. The training process resocializes recruits to the demands made of them by military life. Psychological conditioning techniques are used to shape attitudes and behaviours, so that recruits will obey all orders, face mortal danger, and kill their opponents in battle. According to an expert in United States military training methods, Dave Grossman, recruit ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Neurobiology
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cellular studies of individual neurons to imaging of sensory, motor and cognitive tasks in the brain. History The earliest ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Antioxidant
Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals. This can lead to polymerization and other chain reactions. They are frequently added to industrial products, such as fuels and lubricants, to prevent oxidation, and to foods to prevent spoilage, in particular the rancidification of oils and fats. In cells, antioxidants such as glutathione, mycothiol or bacillithiol, and enzyme systems like superoxide dismutase, can prevent damage from oxidative stress. The only dietary antioxidants are vitamins A, C, and E, but the term ''antioxidant'' has also been applied to numerous other dietary compounds that only have antioxidant properties in vitro, with little evidence for antioxidant properties in vivo. Dietary supplements marketed as antioxidants have not been shown to maintain health or prevent disease in humans. History As part of their adaptation from marine life, terrestrial plants began producing non-marine antioxi ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Immune System
The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as cancer cells and objects such as wood splinters, distinguishing them from the organism's own healthy tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli. The adaptive immune system provides a tailored response to each stimulus by learning to recognize molecules it has previously encountered. Both use molecules and cells to perform their functions. Nearly all organisms have some kind of immune system. Bacteria have a rudimentary immune system in the form of enzymes that protect against virus infections. Other basic immune mechanisms evolved in ancient plants and animals and remain in their modern descendants. These mechanisms include phagocytosis, antimicrobial pe ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Roy Walford
Roy Lee Walford, M. D. (June 29, 1924 – April 27, 2004) was a professor of pathology at University of California, Los Angeles School of Medicine, a leading advocate of calorie restriction for life extension and health improvement, and a crew member of Biosphere 2. Career highlights Walford is credited with significantly furthering aging research by his discovery that laboratory mice, when fed a diet that restricted their caloric intake by 50% yet maintaining nutritional requirements, almost doubled their expected life span. He received his medical degree from the University of Chicago in 1948. He completed his internship at Gorgas Hospital, Panama, and served his residency at the V.A. Medical Center in Los Angeles. He then served two years in the US Air Force during the Korean War. Walford joined the faculty at the University of California at Los Angeles (UCLA) in 1954. He became a Professor of Pathology at the UCLA School of Medicine in 1966. He became Professor of Patholog ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Calorie Restriction
Calorie restriction (caloric restriction or energy restriction) is a dietary regimen that reduces intake of energy from caloric foods & beverages without incurring malnutrition. "Reduce" can be defined relative to the subject's previous intake before intentionally restricting food or beverage consumption, or relative to an average person of similar body type. Calorie restriction is typically adopted intentionally to reduce body weight. It is recommended as a possible regimen by US dietary guidelines and scientific societies for body weight control. Health effects Recommendations Caloric intake control, and reduction for overweight individuals, is recommended by US dietary guidelines and science-based societies. Calorie restriction is recommended for people with diabetes and prediabetes, in combination with physical exercise and a weight loss goal of 5-15% for diabetes and 7-10% for prediabetes to prevent progression to diabetes. and mild calorie restriction may be benefici ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

University Of North Texas
The University of North Texas (UNT) is a public research university in Denton, Texas. It was founded as a nonsectarian, coeducational, private teachers college in 1890 and was formally adopted by the state 11 years later."Denton Normal School," Dallas Morning News, May 25, 1901, p. 2. UNT is a member of the University of North Texas System, which includes additional universities in Dallas and Fort Worth. UNT also has a location in Frisco. The university consists of 14 colleges and schools, an early admissions math and science academy for exceptional high-school-age students from across the state, the Texas Academy of Mathematics and Science, and a library system that comprises the university core. It is classified among "R1: Doctoral Universities – Very high research activity". According to the National Science Foundation, UNT spent $78.4 million on research and development in 2019. Campus The main campus is located in Denton, TX part of the largest metropolitan area in T ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  




Jack Petersen (guitarist)
Jack Leroy Petersen (born October 25, 1933) is an American jazz guitarist and educator. He was a pedagogical architect for jazz guitar and jazz improvisation at Berklee College of Music, University of North Texas College of Music, and University of North Florida. Biography His father, Harold Petersen, worked for LTV and his mother, Effie, worked at Russel-Newman Manufacturing Company. When Jack Petersen was five years old, his family moved to Denton, Texas. He began playing guitar when he was 16 under the influence of Western swing. He won a course in guitar from a radio contest. The teacher was Bob Hames, a former soldier who was attending University of North Texas. Hames introduced Petersen the music of Charlie Christian, Herb Ellis, Tal Farlow, Barry Galbraith, Barney Kessel, Carl Kress, Oscar Moore, Remo Palmieri, Chuck Wayne. While in high school he and his friend Dick Crockett listened to North Texas Lab Bands and the small groups that performed on campus, and developed t ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Dan Haerle
Dan Haerle (born July 23, 1937) is a jazz pianist, composer, author and teacher, based in Denton, Texas. He is professor emeritus of Jazz Studies at the University of North Texas.UNT Counterpoint, Spring 2002 Early life and education Dan Haerle attended Quincy High School. In 1953 he moved with his family to New York where he attended Flushing High School and graduated from Hicksville High School in 1955. In 1957 he moved to Cedar Rapids, Iowa, where he attended Coe College Coe College is a private liberal arts college in Cedar Rapids, Iowa. It was founded in 1851 and is historically affiliated with the Presbyterian Church (USA). The college is a member of the Associated Colleges of the Midwest and the Associatio ... and graduated with a Bachelor of Music Education degree in 1961. Haerle earned a Master of Music in Composition from North Texas State University in 1966.Jazz Education Journal, January/February 2003 Career Haerle began teaching in 1961 at Tri-County Commu ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]