|
VPS11
Vacuolar protein sorting-associated protein 11 homolog is a protein that in humans is encoded by the ''VPS11'' gene. Function Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Interactions VPS11 has been shown to interact with VPS18, VPS33A and STX7 Syntaxin-7 is a protein that in humans is encoded by the ''STX7'' gene. In melanocytic cells STX7 gene expression may be regulated by MITF. Interactions STX7 has been shown to interact with STX8, VPS18, Vesicle-associated membrane protein 8 .... Re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
VPS18
Vacuolar protein sorting-associated protein 18 homolog is a protein that in humans is encoded by the ''VPS18'' gene. Function Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Interactions VPS18 has been shown to interact with VPS11 and STX7 Syntaxin-7 is a protein that in humans is encoded by the ''STX7'' gene. In melanocytic cells STX7 gene expression may be regulated by MITF. Interactions STX7 has been shown to interact with STX8, VPS18, Vesicle-associated membrane protein 8 .... References ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
VPS33A
Vacuolar protein sorting-associated protein 33A is a protein that in humans is encoded by the ''VPS33A'' gene. Function Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and it encodes a protein similar to the yeast class C Vps33 protein. The mammalian class C VPS proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Interactions VPS33A has been shown to interact with VPS11 Vacuolar protein sorting-associated protein 11 homolog is a protein that in humans is encoded by the ''VPS11'' gene. Function Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
