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Visual N1
The visual N1 is a visual evoked potential, a type of event-related electrical potential (ERP), that is produced in the brain and recorded on the scalp. The N1 is so named to reflect the polarity and typical timing of the component. The "N" indicates that the polarity of the component is negative with respect to an average mastoid reference. The "1" originally indicated that it was the first negative-going component, but it now better indexes the typical peak of this component, which is around 150 to 200 milliseconds post-stimulus. The N1 deflection may be detected at most recording sites, including the occipital, parietal, central, and frontal electrode sites.Mangun, G.R., & Hillyard, S.A, (1991). Modulations of sensory-evoked brain potentials indicate changes in perceptual processing during visual-spatial priming. Journal of Experimental Psychology: Human perception and performance, 17(4): 1057-1074. Although, the visual N1 is widely distributed over the entire scalp, it peaks ea ...
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Electroencephalography
Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in the neocortex and allocortex. It is typically non-invasive, with the EEG electrodes placed along the scalp (commonly called "scalp EEG") using the International 10-20 system, or variations of it. Electrocorticography, involving surgical placement of electrodes, is sometimes called " intracranial EEG". Clinical interpretation of EEG recordings is most often performed by visual inspection of the tracing or quantitative EEG analysis. Voltage fluctuations measured by the EEG bioamplifier and electrodes allow the evaluation of normal brain activity. As the electrical activity monitored by EEG originates in neurons in the underlying brain tissue, the recordings made by the electrodes on the surface of the scalp vary in accordance with their orientation and ...
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Evoked Potential
An evoked potential or evoked response is an electrical potential in a specific pattern recorded from a specific part of the nervous system, especially the brain, of a human or other animals following presentation of a Stimulus (physiology), stimulus such as a light flash or a pure tone. Different types of potentials result from stimuli of different Stimulus modality, modalities and types. Evoked potential is distinct from spontaneous potentials as detected by electroencephalography (EEG), electromyography (EMG), or other electrophysiology, electrophysiologic recording method. Such potentials are useful for electrodiagnostic medicine, electrodiagnosis and monitoring (medicine), monitoring that include detections of disease and drug-related sensory dysfunction and intraoperative monitoring of sensory pathway integrity. Evoked potential amplitudes tend to be low, ranging from less than a microvolt to several microvolts, compared to tens of microvolts for EEG, millivolts for EMG, and ...
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Evoked Field
Evoked fields are part of the Magnetoencephalography, magnetoencephalogram. They are brain signals evoked by sensory stimulation, but usually buried by the ongoing brain activity. Repeating the stimulus multiple times and averaging the signals reduces the uncorrelated ongoing activity and reveals the evoked field. Evoked fields are the magnetoencephalographic equivalent to evoked potentials, which are part of the electroencephalography, electroencephalogram. Auditory evoked fields An auditory evoked field (AEF) is a form neural activity that is induced by an auditory stimulus and recorded via magnetoencephalogram, magnetoencephalography, which is an equivalent of auditory evoked potential (AEP) recorded by EEG, electroencephalography. The advantage of AEF over AEP is the powerful spatial resolution provided by magnetic field recording, which AEP lacks. Thus, researchers using AEF often deals with the global responses of the whole brain at the Cerebral cortex, cortical level while fo ...
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N400 (neuroscience)
The N400 is a component of time-locked EEG signals known as event-related potentials (ERP). It is a negative-going deflection that peaks around 400 milliseconds post-stimulus onset, although it can extend from 250-500 ms, and is typically maximal over centro-parietal electrode sites. The N400 is part of the normal brain response to words and other meaningful (or potentially meaningful) stimuli, including visual and auditory words, sign language signs, pictures, faces, environmental sounds, and smells. History The N400 was first discovered by Marta Kutas and Steven Hillyard in 1980. They conducted the first experiment looking at the response to unexpected words in read sentences, expecting to elicit a P300 component. The P300 had previously been shown to be elicited by unexpected stimuli. Kutas and Hillyard therefore used sentences with anomalous endings (i.e.''I take coffee with cream and dog''), expecting to see a P300 to the unexpected sentence-final words. However, instead of el ...
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N170
The N170 is a component of the event-related potential (ERP) that reflects the neural processing of faces, familiar objects or words. Furthermore, the N170 is modulated by prediction error processes. When potentials evoked by images of faces are compared to those elicited by other visual stimuli, the former show increased negativity 130-200 ms after stimulus presentation. This response is maximal over occipito-temporal electrode sites, which is consistent with a source located at the fusiform and inferior-temporal gyri, confirmed by electrocorticography. The N170 generally displays right-hemisphere lateralization and has been linked with the structural encoding of faces, hence is considered to be primarily sensitive to faces. A study, employing transcranial magnetic stimulation combined with EEG, found that N170 can be modulated by top-down influences from prefrontal cortex. History The N170 was first described by Shlomo Bentin and colleagues in 1996, who measured ERPs from parti ...
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N2pc
N2pc refers to an ERP component linked to selective attention.Luck, S. J. (2005). "The operation of attention—millisecond by millisecond—over the first half second." In H. Ogmen & B. G. Breitmeyer (Eds.), ''The first half second: The microgenesis and temporal dynamics of unconscious and conscious visual processes.'' Cambridge, MA: MIT Press The N2pc appears over visual cortex contralateral to the location in space to which subjects are attending; if subjects pay attention to the left side of the visual field, the N2pc appears in the right hemisphere of the brain, and vice versa. This characteristic makes it a useful tool for directly measuring the general direction of a person's attention (either left or right) with fine-grained temporal resolution. History Luck and Hillyard (1990) first observed the N2pc while seeking to document electrophysiological correlates of focused attention during visual search using ERPs. Subjects viewed arrays containing 4-12 items, one of which ...
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N200 (neuroscience)
The N200, or N2, is an event-related potential (ERP) component. An ERP can be monitored using a non-invasive electroencephalography (EEG) cap that is fitted over the scalp on human subjects. An EEG cap allows researchers and clinicians to monitor the minute electrical activity that reaches the surface of the scalp from post-synaptic potentials in neurons, which fluctuate in relation to cognitive processing. EEG provides millisecond-level temporal resolution and is therefore known as one of the most direct measures of covert mental operations in the brain. The N200 in particular is a negative-going wave that peaks 200-350ms post-stimulus and is found primarily over anterior scalp sites. Past research focused on the N200 as a mismatch detector, but it has also been found to reflect executive cognitive control functions, and has recently been used in the study of language (Folstein & Van Petten, 2008; Schmitt, Münte, & Kutas, 2000). History The N2 component starts with the discove ...
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N100 (neuroscience)
In neuroscience, the N100 or N1 is a large, negative-going evoked potential measured by electroencephalography (its equivalent in magnetoencephalography is the M100); it peaks in adults between 80 and 120 milliseconds after the onset of a stimulus, and is distributed mostly over the fronto-central region of the scalp. It is elicited by any unpredictable stimulus in the absence of task demands. It is often referred to with the following P200 evoked potential as the "N100-P200" or "N1-P2" complex. While most research focuses on auditory stimuli, the N100 also occurs for visual (see visual N1, including an illustration), olfactory, heat, pain, balance, respiration blocking, and somatosensory stimuli. The auditory N100 is generated by a network of neural populations in the primary and association auditory cortices in the superior temporal gyrus in Heschl's gyrus and planum temporale. It also could be generated in the frontal and motor areas. The area generating it is larger in the ...
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P600 (neuroscience)
The P600 is an event-related potential (ERP) component, or peak in electrical brain activity measured by electroencephalography (EEG). It is a language-relevant ERP component and is thought to be elicited by hearing or reading grammatical errors and other syntactic anomalies. Therefore, it is a common topic of study in neurolinguistic experiments investigating sentence processing in the human brain. The P600 can be elicited in both visual (reading) and auditory (listening) experiments, and is characterized as a positive-going deflection with an onset around 500 milliseconds after the stimulus that elicits it; it often reaches its peak around 600 milliseconds after presentation of the stimulus (hence its name), and lasts several hundred milliseconds.Different authors give slightly different time periods for the P600; for example, claim it may start as early as 400 milliseconds, and describes it as occurring "between 600–1000 ms. In other words, in the EEG waveform it is ...
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P300 (neuroscience)
The P300 (P3) wave is an event-related potential (ERP) component elicited in the process of decision making. It is considered to be an endogenous potential, as its occurrence links not to the physical attributes of a stimulus, but to a person's reaction to it. More specifically, the P300 is thought to reflect processes involved in stimulus evaluation or categorization. It is usually elicited using the oddball paradigm, in which low-probability target items are mixed with high-probability non-target (or "standard") items. When recorded by electroencephalography (EEG), it surfaces as a positive deflection in voltage with a latency (delay between stimulus and response) of roughly 250 to 500 ms. In the scientific literature a differentiation is often made in the P3, which is divided according to time: Early P3 window (300-400 ms) and Late P3 window (380-440 ms). The signal is typically measured most strongly by the electrodes covering the parietal lobe. The presence, magnitude, ...
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P200
In neuroscience, the visual P200 or P2 is a waveform component or feature of the event-related potential (ERP) measured at the human scalp. Like other potential changes measurable from the scalp, this effect is believed to reflect the post-synaptic activity of a specific neural process. The P2 component, also known as the P200, is so named because it is a positive going electrical potential that peaks at about 200 milliseconds (varying between about 150 and 275 ms) after the onset of some external stimulus. This component is often distributed around the centro-frontal and the parieto-occipital areas of the scalp. It is generally found to be maximal around the vertex (frontal region) of the scalp, however there have been some topographical differences noted in ERP studies of the P2 in different experimental conditions. Research on the visual P2 is at an early stage compared to other more established ERP components and there is much that we still do not know about it. Part of the dif ...
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