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Vindija Cave
Vindija Cave is an archaeological site associated with Neanderthals and modern humans, located in the municipality of Donja Voća, northern Croatia. Three of these Neanderthals were selected as the primary sources for the first draft sequence of the Neanderthal genome project. Description The cave is located roughly west of the city of Varaždin and north of Ivanec. It is estimated that Neanderthals used the cave 40,000 years ago; approximately 8000 years before modern humans lived in that part of Europe. The hominid specimens at level 3G are regarded as unquestionably Neanderthal in overall morphology but exhibit a number of traits that sit closer to anatomically modern Europeans than to the traditional Neanderthal. These include a thinner and less projecting brow ridge, reduced facial size, and narrower front teeth. Though some have put these differences down to the small size of the Vindija individuals, a study conducted in 1995 established that the Vindija Neanderthals, t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Donja Voća
Donja Voća is a municipality in Croatia in Varaždin County Varaždin County ( hr, Varaždinska županija) is a county in Northern Croatia. It is named after its county seat, the city of Varaždin. Geography The county contains the city of Varaždin, the towns of: Ivanec, Ludbreg, Lepoglava, Novi Marof .... According to the 2011 census, there are 2,443 inhabitants. The settlements are: * Budinščak, population 109 * Donja Voća, population 1,059 * Fotez Breg, population 64 * Gornja Voća, population 571 * Jelovec Voćanski, population 86 * Plitvica Voćanska, population 68 * Rijeka Voćanska, population 264 * Slivarsko, population 222 References External links * Municipalities of Croatia Populated places in Varaždin County {{Varaždin-geo-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radiocarbon Dating
Radiocarbon dating (also referred to as carbon dating or carbon-14 dating) is a method for determining the age of an object containing organic material by using the properties of radiocarbon, a radioactive isotope of carbon. The method was developed in the late 1940s at the University of Chicago by Willard Libby. It is based on the fact that radiocarbon () is constantly being created in the Earth's atmosphere by the interaction of cosmic rays with atmospheric nitrogen. The resulting combines with atmospheric oxygen to form radioactive carbon dioxide, which is incorporated into plants by photosynthesis; animals then acquire by eating the plants. When the animal or plant dies, it stops exchanging carbon with its environment, and thereafter the amount of it contains begins to decrease as the undergoes radioactive decay. Measuring the amount of in a sample from a dead plant or animal, such as a piece of wood or a fragment of bone, provides information that can be used to calc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allele
An allele (, ; ; modern formation from Greek ἄλλος ''állos'', "other") is a variation of the same sequence of nucleotides at the same place on a long DNA molecule, as described in leading textbooks on genetics and evolution. ::"The chromosomal or genomic location of a gene or any other genetic element is called a locus (plural: loci) and alternative DNA sequences at a locus are called alleles." The simplest alleles are single nucleotide polymorphisms (SNP). but they can also be insertions and deletions of up to several thousand base pairs. Popular definitions of 'allele' typically refer only to different alleles within genes. For example, the ABO blood grouping is controlled by the ABO gene, which has six common alleles (variants). In population genetics, nearly every living human's phenotype for the ABO gene is some combination of just these six alleles. Most alleles observed result in little or no change in the function of the gene product it codes for. However, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caucasus
The Caucasus () or Caucasia (), is a region between the Black Sea and the Caspian Sea, mainly comprising Armenia, Azerbaijan, Georgia, and parts of Southern Russia. The Caucasus Mountains, including the Greater Caucasus range, have historically been considered as a natural barrier between Eastern Europe and Western Asia. Mount Elbrus in Russia, Europe's highest mountain, is situated in the Western Caucasus. On the southern side, the Lesser Caucasus includes the Javakheti Plateau and the Armenian highlands, part of which is in Turkey. The Caucasus is divided into the North Caucasus and South Caucasus, although the Western Caucasus also exists as a distinct geographic space within the North Caucasus. The Greater Caucasus mountain range in the north is mostly shared by Russia and Georgia as well as the northernmost parts of Azerbaijan. The Lesser Caucasus mountain range in the south is occupied by several independent states, mostly by Armenia, Azerbaijan, and Georgia, but also ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mezmaiskaya Cave
Mezmaiskaya Cave (russian: Мезмайская пещера) is a prehistoric cave site overlooking the right bank of the Sukhoi Kurdzhips (a tributary of the Kurdzhips River) in the southern Russian Republic of Adygea, located in the northwestern foothills of the North Caucasus in the Caucasus Mountains system. Archaeology Neanderthal Initial excavations in the Mezmaiskaya cave recovered Mousterian artifacts of the Last glacial period. The Late Middle Paleolithic stratigraphic layers at Mezmaiskaya are composed of 7 layers, dating from roughly 70,000 to 40,000 BP. Three Neanderthal individuals were recovered from the cave. The first, ''Mezmaiskaya 1'', was recovered in 1993 and is an almost complete skeleton in a well preserved state due to calcite cementation that covers and holds the arrangement in place. It was assessed to be an infant about two weeks old, making it the youngest Neanderthal ever recovered. Although no burial pit was found, circumstances suggest that the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ursus Ingressus
''Ursus ingressus'' (the Gamssulzen Cave bear) is an extinct species of the family Ursidae that lived in Central Europe during the Late Pleistocene. It is named after the Gamssulzen Cave in Austria, where the holotype of this species was found.Gernot Rabeder (2004): Die Höhlenbären der Sulzfluh-Höhlen, Vorarlberger Naturschau 15, Seite 103–114 Description ''Ursus ingressus'' was a large cave bear with massive, bulky limbs. It was larger than ''Ursus spelaeus'', which has been estimated to weigh an average of (male specimen). Behaviour Some studies have suggested the Gamssulzen Cave bear to have been herbivorous, living of vegetation with little contribution of grass. Other studies proposed ''Ursus ingressus'' to have been an omnivore, with participation of terrestrial and more likely aquatic animal protein, that exceeds the participation of animal protein in the diet of the modern brown bear ''(Ursus arctos)''. However it has also been suggested, that the feeding habits ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mitochondrial DNA
Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, such as adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants and algae, also in plastids such as chloroplasts. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. This sequencing revealed that the human mtDNA includes 16,569 base pairs and encodes 13 proteins. Since animal mtDNA evolves faster than nuclear genetic markers, it represents a mainstay of phylogenetics and evolutionary biology. It also permits an examination of the relatedness of populations, and so has become important in anthropology and biogeography. Origin Nuclear and mitochondrial DNA are thought to be of separate evolutionary origin, with the mtDNA being derived ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ZooMS
Zooarchaeology by mass spectrometry, commonly referred to by the abbreviation ZooMS, is a scientific method that identifies animal species by means of characteristic peptide sequences in the protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ... collagen. ZooMS is the most common archaeological application of peptide mass fingerprinting (PMF) and can be used for species identification of bones, teeth, skin and antler. It is commonly used to identify objects that cannot be identified morphologically. In an archaeological context this usually means that the object is too fragmented or that it has been shaped into an artefact. Archaeologists use these species identification to study among others past environments, diet and raw material selection for the production of tools. Develo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peptide Mass Fingerprinting
Peptide mass fingerprinting (PMF) (also known as protein fingerprinting) is an analytical technique for protein identification in which the unknown protein of interest is first cleaved into smaller peptides, whose absolute masses can be accurately measured with a mass spectrometer such as MALDI-TOF or ESI-TOF. The method was developed in 1993 by several groups independently. The peptide masses are compared to either a database containing known protein sequences or even the genome. This is achieved by using computer programs that translate the known genome of the organism into proteins, then theoretically cut the proteins into peptides, and calculate the absolute masses of the peptides from each protein. They then compare the masses of the peptides of the unknown protein to the theoretical peptide masses of each protein encoded in the genome. The results are statistically analyzed to find the best match. The advantage of this method is that only the masses of the peptides have to be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Denisova Cave
Denisova Cave (russian: Денисова пещера, lit= the cave of Denis, translit= Denísova peshchéra; alt, Аю-Таш, lit= Bear Rock, translit= Ayu Tash) is a cave in the Bashelaksky Range of the Altai mountains, Siberia, Russia. The cave has provided items of great paleoarchaeological and paleontological interest. Bone fragments of the Denisova hominin originate from the cave, including artifacts dated to around 40,000 BP. A 32,000-year-old prehistoric species of horse has also been found in the cave. The cave is located in a region thought to have been inhabited concurrently in the past by Neanderthals and by modern humans. A bone needle dated to 50,000 years ago was discovered at the archaeological site in 2016 and has been described as the most ancient needle known (though another possible needle dates to about 10,000 years earlier from South Africa from 61,000 years ago). Denisovans, Neanderthals and related hybrids may have inhabited the Denisova Cave ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coverage (genetics)
Coverage (or depth) in DNA sequencing is the number of unique reads that include a given nucleotide in the reconstructed sequence. Deep sequencing refers to the general concept of aiming for high number of unique reads of each region of a sequence. Rationale Even though the sequencing accuracy for each individual nucleotide is very high, the very large number of nucleotides in the genome means that if an individual genome is only sequenced once, there will be a significant number of sequencing errors. Furthermore, many positions in a genome contain rare single-nucleotide polymorphisms (SNPs). Hence to distinguish between sequencing errors and true SNPs, it is necessary to increase the sequencing accuracy even further by sequencing individual genomes a large number of times. Ultra-deep sequencing The term "ultra-deep" can sometimes also refer to higher coverage (>100-fold), which allows for detection of sequence variants in mixed populations. In the extreme, error-corrected sequ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coverage (genetics)
Coverage (or depth) in DNA sequencing is the number of unique reads that include a given nucleotide in the reconstructed sequence. Deep sequencing refers to the general concept of aiming for high number of unique reads of each region of a sequence. Rationale Even though the sequencing accuracy for each individual nucleotide is very high, the very large number of nucleotides in the genome means that if an individual genome is only sequenced once, there will be a significant number of sequencing errors. Furthermore, many positions in a genome contain rare single-nucleotide polymorphisms (SNPs). Hence to distinguish between sequencing errors and true SNPs, it is necessary to increase the sequencing accuracy even further by sequencing individual genomes a large number of times. Ultra-deep sequencing The term "ultra-deep" can sometimes also refer to higher coverage (>100-fold), which allows for detection of sequence variants in mixed populations. In the extreme, error-corrected sequ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
