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Vibrio Natriegens
''Vibrio natriegens'' is a Gram-negative marine bacterium. It was first isolated from salt marsh mud. It is a salt-loving organism (halophile) requiring about 2% NaCl for growth. It reacts well to the presence of sodium ions which appear to stimulate growth in ''Vibrio'' species, to stabilise the cell membrane, and to affect sodium-dependent transport and mobility. Under optimum conditions, and all nutrients provided, the doubling time of ''V. natriegens'' can be less than 10 minutes. ''V. natriegens'' is able to successfully live and rapidly divide in its coastal areas due its large range of metabolic fuel. Recent research has displayed that ''Vibrio natriegens'' has a flexible metabolism, which allows it to consume a large variety of carbon substrates, reduce nitrates, and even fix nitrogen from the atmosphere under nitrogen-limiting and anaerobic conditions. In the laboratory, the growth medium can be easily changed, thus affecting the growth rate of a culture. ''V. natriegens' ...
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Gram-negative
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall sandwiched between an inner cytoplasmic cell membrane and a bacterial outer membrane. Gram-negative bacteria are found in virtually all environments on Earth that support life. The gram-negative bacteria include the model organism ''Escherichia coli'', as well as many pathogenic bacteria, such as ''Pseudomonas aeruginosa'', ''Chlamydia trachomatis'', and ''Yersinia pestis''. They are a significant medical challenge as their outer membrane protects them from many antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and lysozyme, an antimicrobial enzyme produced by animals that forms part of the innate immune system. Additionally, the outer leaflet of this membrane comprises a complex lipo ...
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Amygdalin
Amygdalin (from Ancient Greek: ' "almond") is a naturally occurring chemical compound found in many plants, most notably in the seeds (kernels) of apricots, bitter almonds, apples, peaches, cherries, and plums. Amygdalin is classified as a cyanogenic glycoside because each amygdalin molecule includes a nitrile group, which can be released as the toxic cyanide anion by the action of a beta-glucosidase. Eating amygdalin will cause it to release cyanide in the human body, and may lead to cyanide poisoning. Since the early 1950s, both amygdalin and a chemical derivative named ''laetrile'' have been promoted as alternative cancer treatments, often under the misnomer vitamin B17 (neither amygdalin nor laetrile is a vitamin). Scientific study has found them to not only be clinically ineffective in treating cancer, but also potentially toxic or lethal when taken by mouth due to cyanide poisoning. The promotion of laetrile to treat cancer has been described in the medical literature a ...
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Bacterial Diversity Metadatabase
Bac''Dive'' (the Bacterial Diversity Metadatabase) is a bacterial metadatabase that provides strain-linked information about bacterial and archaeal biodiversity. Introduction Bac''Dive'' is a resource for different kind of metadata like taxonomy, morphology, physiology, environment and molecular-biology. The majority of data is manually annotated and curated. With the release in July 2018 Bac''Dive'' offers information for 63,669 strains. The database is hosted by the Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH and is part ode.NBIthe German Network for Bioinformatics Infrastructure. Content and Features Database The July 2018 release of the database encompassed over 600 different data fields, divided into the categories "Name and taxonomic classification", "Morphology and physiology", "Culture and growth conditions," "Isolation, sampling and environmental information." "Application and interaction", "Molecular biology" and "Strain av ...
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Frontiers In Microbiology
Frontiers Media SA is a publisher of peer-reviewed, open access, scientific journals currently active in science, technology, and medicine. It was founded in 2007 by Kamila and Henry Markram, and has since expanded to other academic fields. Frontiers is based in Lausanne, Switzerland, with other offices in London, Madrid, Seattle and Brussels. In 2022, Frontiers employed more than 1,400 people, across 14 countries. All Frontiers journals are published under a Creative Commons Attribution License. As of 2022, Frontiers publishes over 185 academic journals, including 48 journals indexed within the Science Citation Index Expanded, and 4 journals indexed within the Social Sciences Citation Index, with a total of 51 journals ranked with an impact factor. Frontiers journals are included in the Directory of Open Access Journals (DOAJ). Frontiers is also a member of the Open Access Scholarly Publishers Association (OASPA), a participating publisher and supporter of the Initiative for O ...
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Journal Of Visualized Experiments
The ''Journal of Visualized Experiments'' (styled ''JoVE'') is a peer-reviewed scientific journal that publishes experimental methods in video format. The journal is based in Cambridge, MA and was established in December 2006. Moshe Pritsker is the CEO and co-founder. Abstracting and indexing ''JoVE'' is abstracted and indexed in Index Medicus, MEDLINE/PubMed, BIOSIS Previews, and Science Citation Index Expanded. According to the ''Journal Citation Reports'', the journal had a 2020 impact factor of 1.4. Format and scope ''JoVE'' covers research methods and experimental techniques from both the physical and life sciences. The journal currently has 13 sections: Biology, Developmental Biology, Neuroscience, Immunology and Infection, Medicine, Bioengineering, Engineering, Chemistry, Behavior, Environment, Biochemistry, Cancer Research, and Genetics. JoVE also publishes Science Education collections aimed at instructing scientists in fundamental concepts and methods in a range of fi ...
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ACS Synthetic Biology
''ACS Synthetic Biology'' is a peer-reviewed scientific journal published by the American Chemical Society. It began publishing accepted articles in the Fall of 2011, with the first full monthly issue published in January 2012. It covers all aspects of synthetic biology, including molecular, systems, and synthetic research. The founding editor-in-chief is Christopher Voigt (Massachusetts Institute of Technology). Types of articles The journal publishes * Letters: Short reports of original research focused on an individual finding * Articles: Original research presenting findings of immediate, broad interest. * Reviews: Expert perspectives and analyses of recently published research * Technical Notes: Concise communications that focus on the characterization of new or interesting tools and websites * Tutorials: Detailed descriptions of synthetic, computational, and systems methodologies References External links * See also * Systems and Synthetic Biology {{American Chem ...
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Nature Methods
''Nature Methods'' is a monthly peer-reviewed scientific journal covering new scientific techniques. It was established in 2004 and is published by Springer Nature under the Nature Portfolio. Like other ''Nature'' journals, there is no external editorial board and editorial decisions are made by an in-house team, although peer review by external experts forms a part of the review process. Every year, the journal highlights a field, approach, or technique that has enabled recent major advances in life sciences research as the "Method of the Year". According to the ''Journal Citation Reports'', the journal had a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 47.99, ranking it first in the category "Biochemical Research Methods". References External link ...
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BioRxiv
bioRxiv (pronounced "bio-archive") is an open access preprint repository for the biological sciences co-founded by John Inglis and Richard Sever in November 2013. It is hosted by the Cold Spring Harbor Laboratory (CSHL). As preprints, papers hosted on bioRxiv are not peer-reviewed, but undergo basic screening and checked against plagiarism. However, peer reviews from other sources may be posted alongside preprints. Moreover, readers may post comments. It has been measured that two thirds of the papers posted in bioRxiv are later published in peer-reviewed journals. A service called Rxivist parses the metadata of preprints from bioRxiv, and combines it with data from Twitter allowing to detect trending preprints. MedRxiv, and its sister site, bioRxiv, have been major sources for the dissemination of COVID-19 research. History BioRxiv was inspired by and intends to complement the arXiv repository, which mostly focuses on mathematics, physics and connected disciplines, launche ...
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D-Turanose
Turanose is a reducing disaccharide. The -isomer is naturally occurring. Its systematic name is α--glucopyranosyl-(1→3)-α--fructofuranose. It is an analog of sucrose not metabolized by higher plants, but rather acquired through the action of sucrose transporters for intracellular carbohydrate signaling. In addition to its involvement in signal transduction, -(+)-turanose can also be used as a carbon source by many organisms including numerous species of bacteria and fungi.D-Turanose
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Sigma-Aldrich Sigma-Aldrich (formally MilliporeSigma) is an American chemical, life science, and biotechnology company that is owned by the German chemical conglomerate Merck Group. Sigma-Aldrich w ...
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Glycogen
Glycogen is a multibranched polysaccharide of glucose that serves as a form of energy storage in animals, fungi, and bacteria. The polysaccharide structure represents the main storage form of glucose in the body. Glycogen functions as one of two forms of energy reserves, glycogen being for short-term and the other form being triglyceride stores in adipose tissue (i.e., body fat) for long-term storage. In humans, glycogen is made and stored primarily in the cells of the liver and skeletal muscle. In the liver, glycogen can make up 5–6% of the organ's fresh weight, and the liver of an adult, weighing 1.5 kg, can store roughly 100–120 grams of glycogen. In skeletal muscle, glycogen is found in a low concentration (1–2% of the muscle mass) and the skeletal muscle of an adult weighing 70 kg stores roughly 400 grams of glycogen. The amount of glycogen stored in the body—particularly within the muscles and liver—mostly depends on physical training, bas ...
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Trehalose
Trehalose (from Turkish '' tıgala'' – a sugar derived from insect cocoons + -ose) is a sugar consisting of two molecules of glucose. It is also known as mycose or tremalose. Some bacteria, fungi, plants and invertebrate animals synthesize it as a source of energy, and to survive freezing and lack of water. Extracting trehalose was once a difficult and costly process, but around 2000, the Hayashibara company ( Okayama, Japan) discovered an inexpensive extraction technology from starch. Trehalose has high water retention capabilities, and is used in food, cosmetics and as a drug. A procedure developed in 2017 using trehalose allows sperm storage at room temperatures. Structure Trehalose is a disaccharide formed by a bond between two α-glucose units. It is found in nature as a disaccharide and also as a monomer in some polymers. Two other isomers exist, α,β-trehalose, otherwise known as neotrehalose, and β,β-trehalose (also referred to as isotrehalose). Neotrehalose has ...
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Melibiose
Melibiose is a reducing disaccharide formed by an α-1,6 linkage between galactose and glucose (D-Gal-α(1→6)-D-Glc). It differs from lactose in the chirality of the carbon where the galactose ring is closed and that the galactose is linked to a different point on the glucose moiety. It can be formed by invertase-mediated hydrolysis of raffinose, which produces melibiose and fructose. Melibiose can be broken down into its component saccharides, glucose and galactose, by the enzyme alpha-galactosidase, such as MEL1 from ''Saccharomyces pastorianus'' (lager yeast). Melibiose cannot be used by ''Saccharomyces cerevisiae ''Saccharomyces cerevisiae'' () (brewer's yeast or baker's yeast) is a species of yeast (single-celled fungus microorganisms). The species has been instrumental in winemaking, baking, and brewing since ancient times. It is believed to have been o ...'' (ale yeast), this is one test to differentiate between the two yeast species. References {{reflist Disacchari ...
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