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Ventral Lateral Nucleus
The ventral lateral nucleus (VL) is a nucleus in the ventral nuclear group of the thalamus. Inputs and outputs It receives neuronal inputs from the basal ganglia which includes the substantia nigra and the globus pallidus (via the thalamic fasciculus). It also has inputs from the cerebellum (via the dentatothalamic tract). It sends neuronal output to the primary motor cortex and premotor cortex. The ventral lateral nucleus in the thalamus forms the motor functional division in the thalamic nuclei along with the ventral anterior nucleus. The ventral lateral nucleus receives motor information from the cerebellum and the globus pallidus. Output from the ventral lateral nucleus then goes to the primary motor cortex. Functions The function of the ventral lateral nucleus is to target efferents including the motor cortex, premotor cortex, and supplementary motor cortex. Therefore, its function helps the coordination and planning of movement. It also plays a role in the learning of mov ...
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Midline Nuclear Group
The midline nuclear group (or midline thalamic nuclei) is a region of the thalamus consisting of the following nuclei: * paraventricular nucleus of thalamus (''nucleus paraventricularis thalami'') - not to be confused with paraventricular nucleus of hypothalamus * paratenial nucleus The paratenial nucleus, or parataenial nucleus ( la, nucleus parataenialis), is a component of the midline nuclear group in the thalamus. It is sometimes subdivided into the nucleus parataenialis interstitialis and nucleus parataenialis parvocellu ... (''nucleus parataenialis'') * nucleus reuniens * rhomboid nucleus (''nucleus commissuralis rhomboidalis'') * subfascicular nucleus (''nucleus subfascicularis'') The midline nuclei are often called "nonspecific" in that they project widely to the cortex and elsewhere. This has led to the assumption that they may be involved in general functions such as alerting. However, anatomical connections might suggest more specific functions, with the paraventr ...
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Thalamus
The thalamus (from Greek θάλαμος, "chamber") is a large mass of gray matter located in the dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, allowing hub-like exchanges of information. It has several functions, such as the relaying of sensory signals, including motor signals to the cerebral cortex and the regulation of consciousness, sleep, and alertness. Anatomically, it is a paramedian symmetrical structure of two halves (left and right), within the vertebrate brain, situated between the cerebral cortex and the midbrain. It forms during embryonic development as the main product of the diencephalon, as first recognized by the Swiss embryologist and anatomist Wilhelm His Sr. in 1893. Anatomy The thalamus is a paired structure of gray matter located in the forebrain which is superior to the midbrain, near the center of the brain, with nerve fibers projecting out to the ...
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Ventral Anterior Nucleus
The ventral anterior nucleus (VA) is a nucleus of the thalamus. It acts with the anterior part of the ventral lateral nucleus to modify signals from the basal ganglia. Inputs and outputs The ventral anterior nucleus receives neuronal inputs from the basal ganglia. Its main afferent fibres are from the globus pallidus. The efferent fibres from this nucleus pass into the premotor cortex The premotor cortex is an area of the motor cortex lying within the frontal lobe of the brain just anterior to the primary motor cortex. It occupies part of Brodmann's area 6. It has been studied mainly in primates, including monkeys and humans. ... for initiation and planning of movement. Functions It helps to function in movement by providing feedback for the outputs of the basal ganglia. Additional images File:Constudthal.gif, Thalamus File:Territoriostalamo.svg, Thalamus References {{DEFAULTSORT:Ventral Anterior Nucleus Thalamus ...
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List Of Thalamic Nuclei
This traditional list does not accord strictly with human thalamic anatomy. Nuclear groups of the thalamus include: *anterior nuclear group ** anteroventral nucleus ** anterodorsal nucleus ** anteromedial nucleus **superficial ("lateral dorsal") *medial nuclear group (or dorsomedial nucleus) ** parvocellular part **magnocellular part *midline nuclear group or paramedian **paratenial nucleus ** paraventricular nucleus of thalamus **reuniens nucleus **rhomboidal nucleus *Intralaminar nuclear group ( Intralaminar nuclei) **anterior (rostral) group *** paracentral nucleus ***central lateral nucleus ***central medial nucleus **posterior (caudal) intralaminar group ***centromedian nucleus ***parafascicular nucleus *lateral nuclear group in fact a false entity replaced by **posterior region *** pulvinar ****anterior pulvinar nucleus **** lateral pulvinar nucleus **** medial pulvinar nucleus **** inferior pulvinar nucleus *** lateral posterior nucleus belongs to pulvinar ***( lateral ...
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Premotor Cortex
The premotor cortex is an area of the motor cortex lying within the frontal lobe of the brain just anterior to the primary motor cortex. It occupies part of Brodmann's area 6. It has been studied mainly in primates, including monkeys and humans. The functions of the premotor cortex are diverse and not fully understood. It projects directly to the spinal cord and therefore may play a role in the direct control of behavior, with a relative emphasis on the trunk muscles of the body. It may also play a role in planning movement, in the spatial guidance of movement, in the sensory guidance of movement, in understanding the actions of others, and in using abstract rules to perform specific tasks. Different subregions of the premotor cortex have different properties and presumably emphasize different functions. Nerve signals generated in the premotor cortex cause much more complex patterns of movement than the discrete patterns generated in the primary motor cortex. Structure The premo ...
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Primary Motor Cortex
The primary motor cortex (Brodmann area 4) is a brain region that in humans is located in the dorsal portion of the frontal lobe. It is the primary region of the motor system and works in association with other motor areas including premotor cortex, the supplementary motor area, posterior parietal cortex, and several subcortical brain regions, to plan and execute voluntary movements. Primary motor cortex is defined anatomically as the region of cortex that contains large neurons known as Betz cells, which, along with other cortical neurons, send long axons down the spinal cord to synapse onto the interneuron circuitry of the spinal cord and also directly onto the alpha motor neurons in the spinal cord which connect to the muscles. At the primary motor cortex, motor representation is orderly arranged (in an inverted fashion) from the toe (at the top of the cerebral hemisphere) to mouth (at the bottom) along a fold in the cortex called the central sulcus. However, some body parts ...
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Dentatothalamic Tract
The dentatothalamic tract (or dentatorubrothalamic tract) is a tract which originates in the dentate nucleus and follows the ipsilateral superior cerebellar peduncle, decussating later on and reaching the contralateral red nucleus and the contralateral thalamus. The term "dentatorubrothalamocortical" is sometimes used to emphasize termination in the cerebral cortex. Additional images File:Tractography_-_Dentatothalamic_tract_-_animation_3.gif, 3D data of the dentatothalamic tract. Reonctructed using tractography. See also * Cerebellothalamic tract * Red nucleus References External links * NIF Search - Dentatothalamic Tractvia the Neuroscience Information Framework The Neuroscience Information Framework is a repository of global neuroscience web resources, including experimental, clinical, and translational neuroscience databases, knowledge bases, atlases, and genetic/genomic resources and provides many auth ... * https://web.archive.org/web/20091021004541/http://isc.t ...
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Cerebellum
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebellum plays an important role in motor control. It may also be involved in some cognition, cognitive functions such as attention and language as well as emotion, emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to Motor coordination, coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in Fine motor skill, fine movement, Equilibrioception, equilibrium, Human positions, posture, and motor learning in humans. Anatomica ...
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Thalamic Fasciculus
The thalamic fasciculus is a component of the subthalamus. It is synonymous with field H1 of Forel. Nerve fibres form a tract containing cerebellothalamic (crossed) and pallidothalamic (uncrossed) fibres, that is insinuated between the thalamus and the zona incerta. The thalamic fasciculus consists of fibers from the ansa lenticularis and from the lenticular fasciculus, coming from different portions of the medial globus pallidus, before they jointly enter the ventral anterior nucleus of the thalamus The thalamus (from Greek θάλαμος, "chamber") is a large mass of gray matter located in the dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, .... References External links * http://www.meddean.luc.edu/lumen/MedEd/Neuro/frames/nlDEs/nl06fr.htm * https://web.archive.org/web/20070419222336/http://www.endotext.org/neuroendo/neuroendo3b/neuroendo3b_2.htm (see figure #12) * https ...
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Globus Pallidus
The globus pallidus (GP), also known as paleostriatum or dorsal pallidum, is a subcortical structure of the brain. It consists of two adjacent segments, one external, known in rodents simply as the globus pallidus, and one internal, known in rodents as the entopeduncular nucleus. It is part of the telencephalon, but retains close functional ties with the subthalamus in the diencephalon – both of which are part of the extrapyramidal motor system. The globus pallidus is a major component of the basal ganglia, with principal inputs from the striatum, and principal direct outputs to the thalamus and the substantia nigra. The latter is made up of similar neuronal elements, has similar afferents from the striatum, similar projections to the thalamus, and has a similar synaptology. Neither receives direct cortical afferents, and both receive substantial additional inputs from the intralaminar thalamus. Globus pallidus is Latin for "pale globe". Structure Pallidal nuclei are ma ...
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Substantia Nigra
The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement. ''Substantia nigra'' is Latin for "black substance", reflecting the fact that parts of the substantia nigra appear darker than neighboring areas due to high levels of neuromelanin in dopaminergic neurons. Parkinson's disease is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. Although the substantia nigra appears as a continuous band in brain sections, anatomical studies have found that it actually consists of two parts with very different connections and functions: the pars compacta (SNpc) and the pars reticulata (SNpr). The pars compacta serves mainly as a projection to the basal ganglia circuit, supplying the striatum with dopamine. The pars reticulata conveys signals from the basal ganglia to numerous other brain structures. Structure The substantia nigra, along with four other nuclei, is part ...
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Basal Ganglia
The basal ganglia (BG), or basal nuclei, are a group of subcortical nuclei, of varied origin, in the brains of vertebrates. In humans, and some primates, there are some differences, mainly in the division of the globus pallidus into an external and internal region, and in the division of the striatum. The basal ganglia are situated at the base of the forebrain and top of the midbrain. Basal ganglia are strongly interconnected with the cerebral cortex, thalamus, and brainstem, as well as several other brain areas. The basal ganglia are associated with a variety of functions, including control of voluntary motor movements, procedural learning, habit learning, conditional learning, eye movements, cognition, and emotion. The main components of the basal ganglia – as defined functionally – are the striatum, consisting of both the dorsal striatum (caudate nucleus and putamen) and the ventral striatum (nucleus accumbens and olfactory tubercle), the globus pallidus, ...
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