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Val158Met
In genetics, rs4680 (Val158Met) is a genetic variant. It is a single nucleotide polymorphism (SNP) in the '' COMT'' gene that codes catechol-''O''-Methyltransferase. The single nucleotide substitution between G--> A results in an amino acid change from valine to methionine at codon 158. The A or Met allele is associated with lower enzymatic activity (due to thermoinstability), and with exploratory behaviour. The polymorphism has been much studied in schizophrenia research but as of November 2011 meta-analysis in the '' SzGene'' database shows no or very little effect. Several personality genetics studies have examined the association of the polymorphism with personality traits including extroversion, risk aversion In economics and finance, risk aversion is the tendency of people to prefer outcomes with low uncertainty to those outcomes with high uncertainty, even if the average outcome of the latter is equal to or higher in monetary value than the more ce ..., and novelty s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COMT
Catechol-''O''-methyltransferase (COMT; ) is one of several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine, and norepinephrine), catecholestrogens, and various drugs and substances having a catechol structure. In humans, catechol-''O''-methyltransferase protein is encoded by the COMT gene. Two isoforms of COMT are produced: the soluble short form (S-COMT) and the membrane bound long form (MB-COMT). As the regulation of catecholamines is impaired in a number of medical conditions, several pharmaceutical drugs target COMT to alter its activity and therefore the availability of catecholamines. COMT was first discovered by the biochemist Julius Axelrod in 1957. Function Catechol-''O''-methyltransferase is involved in the inactivation of the catecholamine neurotransmitters (dopamine, epinephrine, and norepinephrine). The enzyme introduces a methyl group to the catecholamine, which is donated by S-adenosyl methionine (SAM). Any compound having a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Young Shin Kim
Young may refer to: * Offspring, the product of reproduction of a new organism produced by one or more parents * Youth, the time of life when one is young, often meaning the time between childhood and adulthood Music * The Young, an American rock band * ''Young'', an EP by Charlotte Lawrence, 2018 Songs * "Young" (Baekhyun and Loco song), 2018 * "Young" (The Chainsmokers song), 2017 * "Young" (Hollywood Undead song), 2009 * "Young" (Kenny Chesney song), 2002 * "Young" (Place on Earth song), 2018 * "Young" (Tulisa song), 2012 * "Young", by Ella Henderson, 2019 * "Young", by Lil Wayne from '' Dedication 6'', 2017 * "Young", by Nickel Creek from ''This Side'', 2002 * "Young", by Sam Smith from ''Love Goes'', 2020 * "Young", by Silkworm from '' Italian Platinum'', 2002 * "Young", by Vallis Alps, 2015 * "Young", by Pixey, 2016 People Surname * Young (surname) Given name * Young (Korean name), Korean unisex given name and name element * Young Boozer (born 1948), American banke ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Margaret Daniele Fallin
Margaret is a female first name, derived via French () and Latin () from grc, μαργαρίτης () meaning "pearl". The Greek is borrowed from Persian. Margaret has been an English name since the 11th century, and remained popular throughout the Middle Ages. It became less popular between the 16th century and 18th century, but became more common again after this period, becoming the second-most popular female name in the United States in 1903. Since this time, it has become less common, but was still the ninth-most common name for women of all ages in the United States as of the 1990 census. Margaret has many diminutive forms in many different languages, including Maggie, Madge, Daisy, Margarete, Marge, Margo, Margie, Marjorie, Meg, Megan, Rita, Greta, Gretchen, and Peggy. Name variants Full name * (Irish) * (Irish) * (Dutch), (German), (Swedish) * (English) Diminutives * (English) * (English) First half * ( French) * (Welsh) Second half * (English), (G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Murray B
Murray may refer to: Businesses * Murray (bicycle company), an American manufacturer of low-cost bicycles * Murrays, an Australian bus company * Murray International Trust, a Scottish investment trust * D. & W. Murray Limited, an Australian wholesale drapery business * John Murray (publishing house), a British publishing house Fictional characters * Murray Monster, a muppet in ''Sesame Street'' *Little Murray Sparkles, a cat in ''Sesame Street'' * Murray (''Monkey Island''), a character in the video game series * Murray (''Sly Cooper''), a character in the video game series *Murray Slaughter, a regular character in ''The Mary Tyler Moore Show'' *Murray, the mascot of the band Dio *Murray, in the 2015 Netflix series '' Richie Rich'' *Murray, a ''Hotel Transylvania'' character *Murray the Cop, in ''Fat Pizza'' *Murray Smith, in ''Swift and Shift Couriers'' People *Murray (surname) *Murray (given name) Places Australia * Division of Murray, federal electoral district in Victor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hiroshi Kunugi
is a common masculine Japanese given name. It can also be transliterated as Hirosi. Possible writings Hiroshi can be written using different kanji characters and can mean: *浩, "meaning" *汎 *弘, *宏, *寛, *洋, *博, *博一, *博司, *博史, *弘詩, *大嗣, *博司, *博史, *弘詩, *大嗣, People with the name *, Japanese comedian *Hiroshi Abe (other), multiple people *, Japanese actor *, Japanese astronomer *Hiroshi Abe (war criminal) (born 1922), Japanese soldier *, Japanese screenwriter and film director *, Japanese baseball player *, Japanese actor *, Japanese handball player *Hiroshi Hara (other), multiple people * Hiroshi Hashimoto (other), multiple people *Hiroshi Honda (other), multiple people *, Japanese ice hockey player *, Japanese footballer *, Japanese bobsledder *, Japanese film director *, Japanese footballer *, Japanese diplomat *, Japanese electrical engineer *, Japanese lepidopterist *, Japanese bryologist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Masatoshi Takeda
Masatoshi (written: , , , , , , , , , , , , or ) is a masculine Japanese given name. Notable people with the name include: *, Japanese politician *, Japanese film director *, Japanese politician *, Japanese comedian *, Japanese samurai *, Japanese ''daimyō'' *, Japanese cyclist *, Japanese samurai and ''daimyō'' * Masatoshi Ishida (other), multiple people *, Japanese businessman *, Japanese manga artist *, Japanese physicist *, Japanese footballer *, Japanese politician *, Japanese guitarist *, Japanese footballer *, Japanese footballer *, Japanese footballer *, Japanese diplomat *, Japanese actor *Masatoshi Nagatomi Masatoshi Nagatomi (September 1, 1926 – June 3, 2000) was Japanese professor of Buddhist studies at Harvard University. He was also known by his nickname "Mas." Nagatomi is remembered for introducing the term ''Nikaya Buddhism'' as a replacement ... (1926–2000), Japanese professor of Buddhist studies at Harvard University *, Japanese photographer *, Ja ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yuka Yasuda
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Yuka may refer to: *Yuka (music), an Afro-Cuban style of music *Yuka (mammoth), mammoth specimen found in Yakutia, Russia *Manshu Yuka Kogyo K.K. Ssuningkai, a Japanese-German pre-WWII industrial co-operation People *Yuka (name), a Japanese personal name *Yuka (singer) (born 1970), Japanese singer See also *Yuca, a plant species *Yucca (other) ''Yucca'' is a genus in the plant family Asparagaceae containing species commonly known as yuccas. Yucca may also refer to: *''Hesperoyucca whipplei'', a species of flowering plant closely related to, and formerly usually included in, the genu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kazutaka Ohi
Kazutaka (written: 一貴, 一宇, 一孝, 和隆 or 教隆) is a masculine Japanese given name. Notable people with the name include: * Kazutaka Kogi (born 1933), Japanese academic *, Japanese ultra-nationalist and murderer *, Japanese mechanical designer *, Japanese footballer *, Japanese sumo wrestler *, Japanese baseball player See also * 8087 Kazutaka, a main-belt asteroid {{given name Japanese masculine given names ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hiroaki Hori
Hiroaki is a masculine Japanese given name. It can be written in many ways. In the following lists, the kanji in parentheses are the individual's way of writing the name Hiroaki. Possible writings *(written: , , , , , , , , , , , , , , , , , , , , , , , , , or ) People with the name *, Japanese admiral *, Japanese businessman *, Japanese volleyball player *, Japanese hammer thrower *, Japanese diplomat *, Japanese anime director and screenwriter *, Japanese serial killer *, Japanese prince *, Japanese judoka *, Japanese footballer *, Japanese voice actor *, Japanese racing driver *, Japanese modern pentathlete *, Japanese footballer *, Japanese scientist *, Japanese footballer *, Japanese snowboarder *, Japanese baseball player *, Japanese footballer and manager *, Japanese virologist *, Japanese voice actor *Hiroaki Morino is a Japanese ceramist. His pseudonym is . His real name is Hiroaki Morino. Overviews He is a Japanese potter from Kyoto born in 1934. His father, Mor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hiroko Noguchi
is a common feminine Japanese given name. Name meanings Hiroko can be written using different kanji characters and can mean: *裕子, "kind child" *弘子, "Beautiful child" *寛子, " small child" *浩子, "large child" *博子, "wise child" *宏子, "large child" *広子, "broad child" *紘子, "large child" The name can also be written in hiragana or katakana. People with the name * Hiroko Anzai (安西 ひろこ, born 1979), Japanese model and idol * Hiroko Hatano (畑野 ひろ子, born 1975), Japanese supermodel and actress *, better known as Chikage Oogi, Japanese actress and politician *, Japanese singer, actress and television personality *, Japanese archer *, Japanese fencer *, Japanese slalom canoeist * Hiroko Konishi (小西 寛子, born 1975), Japanese voice actress *, Japanese handball player *, Japanese swimmer *, Japanese model *, Japanese writer * Hiroko Mita (三田 寛子, born 1966), Japanese singer and actress * Hiroko Moriguchi (森口 博子, born 1968), J ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
