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Vaccines Manufacturing And Innovation Centre
The Vaccines Manufacturing and Innovation Centre (VMIC) is a vaccine research and manufacturing facility under construction in Harwell Science and Innovation Campus in Oxfordshire, England. Announced in December 2018 and originally planned to be opened in 2022, its planned opening date has been brought forward to 2021 as a response to the COVID-19 pandemic. Organizations collaborating in the centre's development include Imperial College London, the London School of Hygiene and Tropical Medicine, and Oxford University. The UK government provided funding of £93 million for the construction of the centre in 2020, and by March 2021 total funding reached £215m. Construction of the 7,000 square metre facility at Harwell, Oxfordshire, Harwell was begun by main contractor Glencar in April 2020. In 2020, the centre's personnel contributed to development of the Oxford–AstraZeneca COVID-19 vaccine AZD1222, and from October began medium-scale production. References External links ...
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Vaccine
A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or Antigen, killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic vaccines, therapeutic (to fight a disease that has already occurred, such as cancer vaccine, cancer).
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Harwell Science And Innovation Campus
The Harwell Science and Innovation Campus is a 700-acre science and technology campus in Oxfordshire, England. Over 6,000 people work there in over 240 public and private sector organisations, working across sectors including Space, Clean Energy, Life Sciences and Quantum Computing. The site is outside Didcot, about south of Oxford and roughly east of Wantage. A large part of the site was formerly the main research establishment of the United Kingdom Atomic Energy Authority, but it has seen a transition to its new role as a science and business park as the nuclear facilities have been decommissioned. The campus today Over 6,000 people work on the campus in some 240 organisations representing a multidisciplinary range of advanced scientific and technological disciplines. Major companies and organisations on the site include: * Diamond Light Source Synchrotron * The STFC * Rutherford Appleton Laboratory * Central Laser Facility * ISIS Neutron and Muon Source Space Cl ...
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Oxfordshire
Oxfordshire is a ceremonial and non-metropolitan county in the north west of South East England. It is a mainly rural county, with its largest settlement being the city of Oxford. The county is a centre of research and development, primarily due to the work of the University of Oxford and several notable science parks. These include the Harwell Science and Innovation Campus and Milton Park, both situated around the towns of Didcot and Abingdon-on-Thames. It is a landlocked county, bordered by six counties: Berkshire to the south, Buckinghamshire to the east, Wiltshire to the south west, Gloucestershire to the west, Warwickshire to the north west, and Northamptonshire to the north east. Oxfordshire is locally governed by Oxfordshire County Council, together with local councils of its five non-metropolitan districts: City of Oxford, Cherwell, South Oxfordshire, Vale of White Horse, and West Oxfordshire. Present-day Oxfordshire spanning the area south of the Thames was h ...
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COVID-19 Pandemic
The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identified in an outbreak in the Chinese city of Wuhan in December 2019. Attempts to contain it there failed, allowing the virus to spread to other areas of Asia and later worldwide. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern on 30 January 2020, and a pandemic on 11 March 2020. As of , the pandemic had caused more than cases and confirmed deaths, making it one of the deadliest in history. COVID-19 symptoms range from undetectable to deadly, but most commonly include fever, dry cough, and fatigue. Severe illness is more likely in elderly patients and those with certain underlying medical conditions. COVID-19 transmits when people breathe in air contaminated by droplets and ...
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Imperial College London
Imperial College London (legally Imperial College of Science, Technology and Medicine) is a public research university in London, United Kingdom. Its history began with Prince Albert, consort of Queen Victoria, who developed his vision for a cultural area that included the Royal Albert Hall, Victoria & Albert Museum, Natural History Museum and royal colleges. In 1907, Imperial College was established by a royal charter, which unified the Royal College of Science, Royal School of Mines, and City and Guilds of London Institute. In 1988, the Imperial College School of Medicine was formed by merging with St Mary's Hospital Medical School. In 2004, Queen Elizabeth II opened the Imperial College Business School. Imperial focuses exclusively on science, technology, medicine, and business. The main campus is located in South Kensington, and there is an innovation campus in White City. Facilities also include teaching hospitals throughout London, and with Imperial College Healthcare ...
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London School Of Hygiene And Tropical Medicine
The London School of Hygiene and Tropical Medicine (LSHTM) is a public research university in Bloomsbury, central London, and a member institution of the University of London that specialises in public health and tropical medicine. The institution was founded in 1899 by Sir Patrick Manson, after a donation from the Indian Parsi philanthropist B. D. Petit. Since its foundation it has become one of the most highly placed institutions in global rankings in the fields of public health and infectious diseases. The annual income of the institution for 2020–21 was £244.2 million, of which £167.6 million was from research grants and contracts, with expenditures totalling £235.2 million during the same period. History Origins (1899–1913) The school was founded on October 2, 1899, by Sir Patrick Manson as the London School of Tropical Medicine after the Parsi philanthropist Bomanjee Dinshaw Petit made a donation of £6,666. It was initially located at ...
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Oxford University
Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the University of Oxford, the oldest university in the English-speaking world; it has buildings in every style of English architecture since late Anglo-Saxon. Oxford's industries include motor manufacturing, education, publishing, information technology and science. History The history of Oxford in England dates back to its original settlement in the Saxon period. Originally of strategic significance due to its controlling location on the upper reaches of the River Thames at its junction with the River Cherwell, the town grew in national importance during the early Norman period, and in the late 12th century became home to the fledgling University of Oxford. The city was besieged during The Anarchy in 1142. The university rose to domina ...
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Harwell, Oxfordshire
Harwell is a village and civil parish in the Vale of White Horse about west of Didcot, east of Wantage and south of Oxford. The parish measures about north – south, and almost east – west at its widest point. In 1923 its area was . Historic counties of England, Historically in Berkshire, it has been administered as part of Oxfordshire, England, since the Local Government Act 1972, 1974 boundary changes. The parish includes part of the Milton Park business park in the north and part of Harwell Science and Innovation Campus in the southwest. In the east it includes part of the new Great Western Park housing estate that is contiguous with the built-up area of Didcot. The 2011 United Kingdom census, 2011 census recorded the parish's population as 2,349. Toponymy The earliest known surviving records of Harwell's name are 10th-century Saxon charters now reproduced in the ''Cartularium Saxonicum''. One from 956 records Horn Down, a nearby hill, as ''Harandúne'', which is deriv ...
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Oxford–AstraZeneca COVID-19 Vaccine
The Oxford–AstraZeneca COVID19 vaccine, sold under the brand names Covishield and Vaxzevria among others, is a viral vector vaccine for prevention of COVID-19. Developed in the United Kingdom by Oxford University and British-Swedish company AstraZeneca, using as a vector the modified chimpanzee adenovirus ChAdOx1. The vaccine is given by intramuscular injection. Studies carried out in 2020 showed that the efficacy of the vaccine is 76.0% at preventing symptomatic COVID-19 beginning at 22 days following the first dose, and 81.3% after the second dose. A study in Scotland found that, for symptomatic COVID-19 infection after the second dose, the vaccine is 81% effective against the Alpha variant (lineage B.1.1.7), and 61% against the Delta variant (lineage B.1.617.2). The vaccine is stable at refrigerator temperatures and has a good safety profile, with side effects including injection-site pain, headache, and nausea, all generally resolving within a few days. More rarely, ...
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Medical Research Institutes In The United Kingdom
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancie ...
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Research Institutes Of Imperial College London
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, econom ...
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Research Institutes Of The University Of Oxford
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, econom ...
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