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Vaccine Vial Monitor
A vaccine vial monitor (VVM) is a thermochromic label put on vials containing vaccines which gives a visual indication of whether the vaccine has been kept at a temperature which preserves its potency. The labels were designed in response to the problem of delivering vaccines to developing countries where the cold chain is difficult to preserve, and where formerly vaccines were being rendered inactive and administered ineffectively due to their having been denatured by exposure to ambient temperature. History When international vaccine care standards were being designed in the 1970s, the manuals typically generalized from the needs of care for the oral polio vaccine since that was the most delicate vaccine in wide use. In the 1970s PATH began working with the WHO to develop a system for identifying vaccines which had expired from improper storage. In 1996 the vaccine vial monitor was first used in a vaccine project, and by the next year it was widely accepted for use on many ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thermochromism
Thermochromism is the property of substances to change color due to a change in temperature. A mood ring is an excellent example of this phenomenon, but thermochromism also has more practical uses, such as baby bottles which change to a different color when cool enough to drink, or kettles which change color when water is at or near boiling point. Thermochromism is one of several types of chromism. Organic materials Thermochromatic liquid crystals The two common approaches are based on liquid crystals and leuco dyes. Liquid crystals are used in precision applications, as their responses can be engineered to accurate temperatures, but their color range is limited by their principle of operation. Leuco dyes allow wider range of colors to be used, but their response temperatures are more difficult to set with accuracy. Some liquid crystals are capable of displaying different colors at different temperatures. This change is dependent on selective reflection of certain wavelengt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vials
A vial (also known as a phial or flacon) is a small glass or plastic vessel or bottle, often used to store medication as liquids, powders or capsules. They can also be used as scientific sample vessels; for instance, in autosampler devices in analytical chromatography. Vial-like glass containers date back to classical antiquity; modern vials are often made of plastics such as polypropylene. There are different types of vials such as a single dose vial and multi-dose vials often used for medications. The single dose vial is only used once whereas a multi-dose vial can be used more than once. The CDC sets specific guidelines on multi-dose vials. History and etymology A vial can be tubular, or have a bottle-like shape with a neck. The volume defined by the neck is known as the headspace. The English word "vial" is derived from the Greek ''phiale'', meaning "a broad flat container". Comparable terms include the Latin ''phiala'', Late Latin ''fiola'' and Middle English ''fiole'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vaccines
A vaccine is a biological preparation that provides active acquired immunity The adaptive immune system, also known as the acquired immune system, is a subsystem of the immune system that is composed of specialized, systemic cells and processes that eliminate pathogens or prevent their growth. The acquired immune system ... to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or Antigen, killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylact ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developing Countries
A developing country is a sovereign state with a lesser developed industrial base and a lower Human Development Index (HDI) relative to other countries. However, this definition is not universally agreed upon. There is also no clear agreement on which countries fit this category. The term low and middle-income country (LMIC) is often used interchangeably but refers only to the economy of the countries. The World Bank classifies the world's economies into four groups, based on gross national income per capita: high, upper-middle, lower-middle, and low income countries. Least developed countries, landlocked developing countries and small island developing states are all sub-groupings of developing countries. Countries on the other end of the spectrum are usually referred to as high-income countries or developed countries. There are controversies over this term's use, which some feel it perpetuates an outdated concept of "us" and "them". In 2015, the World Bank declared that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cold Chain
A cold chain is a low temperature-controlled supply chain network. An unbroken cold chain is an uninterrupted series of refrigerated production, storage and distribution activities, along with associated equipment and logistics, which maintain quality via a desired low-temperature range. It is used to preserve and to extend and ensure the shelf life of products, such as fresh agricultural produce, seafood, frozen food, photographic film, chemicals, and pharmaceutical products. Such products, during transport and end-use when in transient storage, are sometimes called cool cargo. Unlike other goods or merchandise, cold chain goods are perishable and always en-route towards end use or destination, even when held temporarily in cold stores and hence commonly referred to as "cargo" during its entire logistics cycle. Adequate cold storage, in particular, can be crucial to prevent quantitative and qualitative food losses. History Mobile refrigeration with ice from the ice trade began ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Denaturation (biochemistry)
In biochemistry, denaturation is a process in which proteins or nucleic acids lose the quaternary structure, tertiary structure, and secondary structure which is present in their native state, by application of some external stress or compound such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), agitation and radiation or heat. If proteins in a living cell are denatured, this results in disruption of cell activity and possibly cell death. Protein denaturation is also a consequence of cell death. Denatured proteins can exhibit a wide range of characteristics, from conformational change and loss of solubility to aggregation due to the exposure of hydrophobic groups. The loss of solubility as a result of denaturation is called ''coagulation''. Denatured proteins lose their 3D structure and therefore cannot function. Protein folding is key to whether a globular or membrane protein can do its job correctly; it must be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Program For Appropriate Technology In Health
PATH (formerly known as the Program for Appropriate Technology in Health) is an international, nonprofit global health organization based in Seattle, with 1,600 employees in more than 70 countries around the world. Its president and CEO is Nikolaj Gilbert, who is also the Managing Director and CEO of Foundations for Appropriate Technologies in Health (FATH), PATH's Swiss subsidiary. PATH focuses on six platforms: vaccines, drugs, diagnostics, devices, system, and service innovations. History Founded in 1977 as the ''Program for the Introduction and Adaptation of Contraceptive Technology'' with a focus on family planning, PATH soon broadened its purpose to work on a wide array of emerging and persistent global health issues in the areas of health technologies, maternal health, child health, reproductive health, vaccines and immunization, and emerging and epidemic diseases such as HIV, malaria, tuberculosis, and COVID-19. Since 2000, PATH expanded from about 300 employees and a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Geneva
Geneva ( ; french: Genève ) frp, Genèva ; german: link=no, Genf ; it, Ginevra ; rm, Genevra is the List of cities in Switzerland, second-most populous city in Switzerland (after Zürich) and the most populous city of Romandy, the French-speaking part of Switzerland. Situated in the south west of the country, where the Rhône exits Lake Geneva, it is the capital of the Canton of Geneva, Republic and Canton of Geneva. The city of Geneva () had a population 201,818 in 2019 (Jan. estimate) within its small municipal territory of , but the Canton of Geneva (the city and its closest Swiss suburbs and exurbs) had a population of 499,480 (Jan. 2019 estimate) over , and together with the suburbs and exurbs located in the canton of Vaud and in the French Departments of France, departments of Ain and Haute-Savoie the cross-border Geneva metropolitan area as officially defined by Eurostat, which extends over ,As of 2020, the Eurostat-defined Functional Urban Area of Geneva was made up of 9 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tech Award
The Tech Awards (expanded in 2016 to The Tech for Global Good) is a program of The Tech Interactive (previously The Tech Museum of Innovation) wherein innovators from any country are recognized for technological contributions which benefit the greatest number of people. History The Tech Interactive created the award in response to The Millennium Project's State of the Future report, which recommends the granting of awards to accelerate technology to improve the human condition. The Tech has granted the awards yearly since 2001 to multiple recipients in each category, and as of 2011, one recipient in each category also gets a cash award of $50,000 from any of various award sponsors. Awards are granted in five categories - environment, economic development, equality, education, and health. In 2012, the categories changed to environment, economic development, education, health, young innovator, and Sustainable Energy. The sustainable energy category will not return in 2013. Along ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Valsad
Valsad (Pronunciation: ‹alsÉ‘É– (Gujarati: વલસાડ), historically known as Bulsar, is a city and a municipality in Valsad district of the Indian state of Gujarat. It is the district headquarters of Valsad district. The city of Valsad is located in the south of Navsari and Surat. Etymology The name "Valsad" derives from ''vad-saal'', a Gujarati language compound meaning "covered (''saal'') by banyan trees (''vad'')" (the area was naturally rich in banyan trees). During British Raj, it was historically known as "Bulsar". Geography Valsad is located at . It has an average elevation of 13 metres (42 feet). The old city is about 4 km inland from the Arabian sea. Climate Valsad has a tropical savanna climate (Aw) with little to no rainfall from October to May and very heavy to extremely heavy rainfall from June to September when it is under the direct influence of the Arabian Sea branch of the South-west monsoon. Demographics As of the 2011 Ind ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hepatitis B Vaccine
Hepatitis B vaccine is a vaccine that prevents hepatitis B. The first dose is recommended within 24 hours of birth with either two or three more doses given after that. This includes those with poor immune function such as from HIV/AIDS and those born premature. It is also recommended that health-care workers be vaccinated. In healthy people routine immunization results in more than 95% of people being protected. Blood testing to verify that the vaccine has worked is recommended in those at high risk. Additional doses may be needed in people with poor immune function but are not necessary for most people. In those who have been exposed to the hepatitis B virus (HBV) but not immunized, hepatitis B immune globulin should be given in addition to the vaccine. The vaccine is given by injection into a muscle. Serious side effects from the hepatitis B vaccine are very uncommon. Pain may occur at the site of injection. It is safe for use during pregnancy or while breastfeeding. It h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
