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VSV-EBOV
Recombinant vesicular stomatitis virus–Zaire Ebola virus (rVSV-ZEBOV), also known as Ebola Zaire vaccine live and sold under the brand name Ervebo, is an Ebola vaccine for adults that prevents Ebola caused by the Zaire ebolavirus. When used in ring vaccination, rVSV-ZEBOV has shown a high level of protection. Around half the people given the vaccine have mild to moderate adverse effects that include headache, fatigue, and muscle pain. rVSV-ZEBOV is a recombinant, replication-competent viral vector vaccine. It consists of rice-derived recombinant human serum albumin and live attenuated recombinant vesicular stomatitis virus (VSV), which has been genetically engineered to express the main glycoprotein from the Zaire ebolavirus so as to provoke a neutralizing immune response to the Ebola virus. The vaccine was approved for medical use in the European Union and the United States in 2019. It was created by scientists at the National Microbiology Laboratory in Winnipeg, Mani ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ebola Vaccine
Ebola vaccines are vaccines either approved or in development to prevent Ebola. As of 2022, there are only vaccines against the Zaire ebolavirus. The first vaccine to be approved in the United States was rVSV-ZEBOV in December 2019. It had been used extensively in the Kivu Ebola epidemic under a compassionate use protocol. During the early 21st century, several vaccine candidates displayed efficacy to protect nonhuman primates (usually macaques) against lethal infection. Vaccines include replication-deficient adenovirus vectors, replication-competent vesicular stomatitis (VSV) and human parainfluenza (HPIV-3) vectors, and virus-like nanoparticle preparations. Conventional trials to study efficacy by exposure of humans to the pathogen after immunization are not ethical in this case. For such situations, the US Food and Drug Administration (FDA) has established the "animal efficacy rule" allowing licensure to be approved on the basis of animal model studies that replicate huma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RVSV-ZEBOV-GP
Recombinant vesicular stomatitis virus–Zaire Ebola virus (rVSV-ZEBOV), also known as Ebola Zaire vaccine live and sold under the brand name Ervebo, is an Ebola vaccine for adults that prevents Ebola caused by the Zaire ebolavirus. When used in ring vaccination, rVSV-ZEBOV has shown a high level of protection. Around half the people given the vaccine have mild to moderate adverse effects that include headache, fatigue, and muscle pain. rVSV-ZEBOV is a recombinant, replication-competent viral vector vaccine. It consists of rice-derived recombinant human serum albumin and live attenuated recombinant vesicular stomatitis virus (VSV), which has been genetically engineered to express the main glycoprotein from the Zaire ebolavirus so as to provoke a neutralizing immune response to the Ebola virus. The vaccine was approved for medical use in the European Union and the United States in 2019. It was created by scientists at the National Microbiology Laboratory in Winnipeg, M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zaire Ebolavirus
''Zaire ebolavirus'', more commonly known as Ebola virus (; EBOV), is one of six known species within the genus ''Ebolavirus''. Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD). Ebola virus has caused the majority of human deaths from EVD, and was the cause of the 2013–2016 epidemic in western Africa, which resulted in at least suspected cases and confirmed deaths. Ebola virus and its genus were both originally named for Zaire (now the Democratic Republic of the Congo), the country where it was first described, and was at first suspected to be a new "strain" of the closely related Marburg virus. The virus was renamed "Ebola virus" in 2010 to avoid confusion. Ebola virus is the single member of the species ''Zaire ebolavirus'', which is assigned to the genus ''Ebolavirus'', family ''Filoviridae'', order ''Mononegavirales''. The members of the species are calle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
EBOV
''Zaire ebolavirus'', more commonly known as Ebola virus (; EBOV), is one of six known species within the genus ''Ebolavirus''. Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD). Ebola virus has caused the majority of human deaths from EVD, and was the cause of the 2013–2016 epidemic in western Africa, which resulted in at least suspected cases and confirmed deaths. Ebola virus and its genus were both originally named for Zaire (now the Democratic Republic of the Congo), the country where it was first described, and was at first suspected to be a new "strain" of the closely related Marburg virus. The virus was renamed "Ebola virus" in 2010 to avoid confusion. Ebola virus is the single member of the species ''Zaire ebolavirus'', which is assigned to the genus ''Ebolavirus'', family ''Filoviridae'', order ''Mononegavirales''. The members of the species are call ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Public Health Agency Of Canada
The Public Health Agency of Canada (PHAC; french: Agence de la santé publique du Canada, ASPC) is an agency of the Government of Canada that is responsible for public health, emergency preparedness and response, and infectious and chronic disease control and prevention. History The PHAC was formed because of a series of official inquiries about the SARS crisis in Canada which was particularly severe. For example, the province of Ontario inquiry and the National Advisory Committee on SARS and Public Health both recommended that a new organisation be formed. It was so instantiated, by Order in Council in 2004 under the Minister of State for Public Health (Canada) of the Martin government and subsequently by legislation that came into force on December 15, 2006 under the Harper government. It is part of the federal government's Health Portfolio (along with Health Canada, the Canadian Institutes of Health Research, and other organizations). At the time of its creation in 2004, mos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Microbiology Laboratory
The National Microbiology Laboratory (NML) is part of the Public Health Agency of Canada (PHAC), the agency of the Government of Canada that is responsible for public health, health emergency preparedness and response, and infectious and chronic disease control and prevention. NML is located in several sites across the country including the Canadian Science Centre for Human and Animal Health (CSCHAH) in Winnipeg, Manitoba. NML has a second site in Winnipeg, the Wilt Infectious Disease Research Centre on Logan Avenue which serves as a hub for HIV research and diagnostics in Canada. The three other primary sites include locations in Guelph, St. Hyacinthe and Lethbridge. The CSCHAH is a biosafety level 4 infectious disease laboratory facility, the only one of its kind in Canada. With maximum containment, scientists are able to work with pathogens including Ebola, Marburg and Lassa fever. The NML's CSCHAH is also home to the Canadian Food Inspection Agency's National Centre for Fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electron Micrograph
A micrograph or photomicrograph is a photograph or digital image taken through a microscope or similar device to show a magnified image of an object. This is opposed to a macrograph or photomacrograph, an image which is also taken on a microscope but is only slightly magnified, usually less than 10 times. Micrography is the practice or art of using microscopes to make photographs. A micrograph contains extensive details of microstructure. A wealth of information can be obtained from a simple micrograph like behavior of the material under different conditions, the phases found in the system, failure analysis, grain size estimation, elemental analysis and so on. Micrographs are widely used in all fields of microscopy. Types Photomicrograph A light micrograph or photomicrograph is a micrograph prepared using an optical microscope, a process referred to as ''photomicroscopy''. At a basic level, photomicroscopy may be performed simply by connecting a camera to a microscope, t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2017 Democratic Republic Of The Congo Ebola Virus Outbreak
The Democratic Republic of the Congo (DRC) was identified by the World Health Organization (WHO) on 11 May 2017 as having one Ebola-related death. As of 8 June 2017, there were five confirmed cases and three probable cases. Of these, four survived and four died. The affected areas of the DRC are Mabongo (one confirmed), Ngayi (one probable), and Nambwa (four confirmed and two probable) in Likati health zone. According to the WHO, "Modelling suggests the risk of further cases is currently low but not negligible.... As of ... June 83% of simulated scenarios predict no further cases in the next 30 days." According to the U.S. Centers for Disease Control and Prevention, "Ebola ... is a rare and deadly disease caused by infection with one of the Ebola virus species. Ebola can cause disease in humans and nonhuman primates (monkeys, gorillas, and chimpanzees)." Ebola was first identified in 1976 near the Ebola River in the DRC. More than 11,300 people died in the 2013 to 2016 E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Institut National Pour La Recherche Biomedicale
The Institut National de la Recherche Biomédicale (INRB) is the national medical research organization of the Democratic Republic of the Congo. The responsible ministry is the Ministry of Scientific Research and Technology. The National Biomedical Research Institute (INRB) was founded in 1984, it is a 70,000 m² establishment. It has been a collaborating center of the World Health Organization since 2018, headed by Professor Jean-Jacques Muyembe-Tamfum, MD, Ph., Which serves as a national biomedical research laboratory for the Ministry of Health of the Democratic Republic of Congo (DRC) ). It is a multidisciplinary institute which collectively has hundreds of years of experience both in the identification, treatment and prevention of diseases in the DRC. Its foundations are the performance of medical and biological analyzes, applied and translational research, the surveillance of communicable diseases and the promotion of professional growth and development. The INRB has continuo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kikwit
Kikwit is the largest city of Kwilu Province, lying on the Kwilu River in the southwestern part of the Democratic Republic of the Congo. Kikwit is also known in the region under the nickname "The Mother". The population is approximately 458,000 (2017). An important commercial centre, it is home to a stadium and is known for its traditional dances, in particular the Bapende dancers whose geographic origin centers on the village of Gungu. Bapende dancers often wear traditional costumes comprising colorful masks and attire made from raffia. Kikwit is also home to an airport (Kikwit Airport) and is connected to the capital Kinshasa by a new road and river transport. In 1995 the city saw a serious outbreak of the deadly Ebola virus. Singer King Kester Emeneya was born in Kikwit in 1956. In April 2014, a tribute concert held in Kikwit to honor King Kester Emeneya ended in disaster, and at least thirteen people in the stadium died in a stampede following a power failure. See also ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2018 Équateur Province Democratic Republic Of The Congo Ebola Virus Outbreak
Eighteen or 18 may refer to: * 18 (number), the natural number following 17 and preceding 19 * one of the years 18 BC, AD 18, 1918, 2018 Film, television and entertainment * ''18'' (film), a 1993 Taiwanese experimental film based on the short story ''God's Dice'' * ''Eighteen'' (film), a 2005 Canadian dramatic feature film * 18 (British Board of Film Classification), a film rating in the United Kingdom, also used in Ireland by the Irish Film Classification Office * 18 (''Dragon Ball''), a character in the ''Dragon Ball'' franchise * "Eighteen", a 2006 episode of the animated television series ''12 oz. Mouse'' Music Albums * ''18'' (Moby album), 2002 * ''18'' (Nana Kitade album), 2005 * '' 18...'', 2009 debut album by G.E.M. Songs * "18" (5 Seconds of Summer song), from their 2014 eponymous debut album * "18" (One Direction song), from their 2014 studio album ''Four'' * "18", by Anarbor from their 2013 studio album '' Burnout'' * "I'm Eighteen", by Alice Cooper commonly r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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