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VRSA Center
VRSA may refer to: * Vancomycin-resistant Staphylococcus aureus, a strain of the bacterium ''Staphylococcus aureus''. * Vila Real de Santo António Municipality Vila may refer to: People *Vila (surname) Places Andorra * Vila, Andorra, a town in the parish of Encamp Brazil * Vila Bela da Santíssima Trindade, a municipality in the State of Mato Grosso * Vila Boa, Goiás, a municipality in the State of ...
, a city and municipality in the Algarve, Portugal. {{disambig ...
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Vancomycin-resistant Staphylococcus Aureus
Vancomycin-resistant ''Staphylococcus aureus'' (VRSA) are strains of ''Staphylococcus aureus'' that have become resistant to the glycopeptide antibiotic vancomycin. Mechanism of acquired resistance Strains of hVISA and vancomycin-intermediate ''Staphylococcus aureus'' (VISA) do not have resistant genes found in ''Enterococcus'' and the proposed mechanisms of resistance include the sequential mutations resulting in a thicker cell wall and the synthesis of excess amounts of D-ala-D-ala residues. VRSA strain acquired the vancomycin resistance gene cluster ''vanA'' from VRE. Diagnosis The diagnosis of vancomycin-resistant Staphylococcus aureus can be done with disk diffusion(and VA screen plate) Treatment of infection For isolates with a vancomycin minimum inhibitory concentration (MIC) , an alternative to vancomycin should be used. The approach is to treat with at least one agent to which VISA/VRSA is known to be susceptible by ''in vitro'' testing. The agents that are used i ...
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