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UFC 183
''UFC 183: Silva vs. Diaz'' was a mixed martial arts event held on January 31, 2015, at MGM Grand Garden Arena in Las Vegas, Nevada. Background The event was headlined by a middleweight bout between former UFC Middleweight champion Anderson Silva and former WEC & Strikeforce Welterweight champion Nick Diaz. A flyweight bout between Ian McCall and John Lineker was originally booked for UFC Fight Night: Shogun vs. St. Preux. However, the bout was canceled on the day of the event as McCall was stricken with a blood infection. The fight was later rescheduled for this event. A middleweight bout between Ed Herman and Derek Brunson was originally booked for UFC on Fox: dos Santos vs. Miocic. However, the bout was cancelled on the day of the event as Brunson was stricken with a stomach ailment. The fight was later rescheduled for this event. Both Kelvin Gastelum and John Lineker missed weight on their first attempts at the weigh ins, coming in at 180 lb and 130 lb respectively. Th ...
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Ultimate Fighting Championship
The Ultimate Fighting Championship (UFC) is an American mixed martial arts (MMA) promotion company based in Las Vegas, Nevada. It is owned and operated by Zuffa, a wholly owned subsidiary of Endeavor Group Holdings. It is the largest MMA promotion company in the world as of 2011. It produces events worldwide that showcase 12 weight divisions (eight men's and four women's) and abides by the Unified Rules of Mixed Martial Arts. , it had held over 600 events. Dana White has been its president since 2001. Under White's stewardship, it has grown into a global multi-billion-dollar enterprise. The UFC was founded by businessman Art Davie and Brazilian martial artist Rorion Gracie, and the first event was held in 1993 at the McNichols Sports Arena in Denver, Colorado. The purpose of the early Ultimate Fighting Championship competitions was to identify the most effective martial art in a contest with minimal rules and no weight classes between competitors of different fighting d ...
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Dos Santos Vs
DOS is shorthand for the MS-DOS and IBM PC DOS family of operating systems. DOS may also refer to: Computing * Data over signalling (DoS), multiplexing data onto a signalling channel * Denial-of-service attack (DoS), an attack on a communications network * Disk operating system ** List of disk operating systems, Apple DOS, Atari DOS, DOS/360, etc. * Distributed operating system Music Albums * ''Dos'' (Altered State album) * ''Dos'' (Dos album) * ''Dos'' (Fanny Lú album) * ''Dos'' (Gerardo album) * ''Dos'' (Malo album), 1972 * ''Dos'' (Myriam Hernández album), 1989 * ''Dos'', album by Wooden Shjips, 2009 * '' ¡Dos!'', album by Green Day Other uses in music * Dos (band), an American band * DOS (concert), by Filipino singer Daniel Padilla Organisations * Democratic Opposition of Serbia, a former political alliance * Department of Space, India * Deutscher Olympischer Sportbund * Directorate of Overseas Surveys, UK 1957–1984 *Dominus Obsequious Sororium, within cu ...
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Tadalafil
Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension. It is taken by mouth. Onset is typically within half an hour and the duration is up to 36 hours. Common side effects include headache, muscle pain, flushed skin, and nausea. Caution is advised in those with cardiovascular disease. Rare but serious side effects include a prolonged erection that can lead to damage to the penis, vision problems, and hearing loss. Tadalafil is not recommended in people taking nitrovasodilators such as nitroglycerin, as this may result in a serious drop in blood pressure. Tadalafil is a PDE5 inhibitor which increases blood flow to the penis. It also dilates blood vessels in the lungs, which lowers the pulmonary artery pressure. Tadalafil was approved for medical use in the United States in 2003. It is available as a generic medication. In 2020, it was the 261s ...
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Temazepam
Temazepam (sold under the brand names Restoril among others) is a medication of the benzodiazepine class which is generally used to treat severe or debilitating insomnia. It is taken by mouth. Temazepam is rapidly absorbed, and significant hypnotic effects begin in less than 30 minutes and can last for up to eight hours. Many studies, some going as far back as the early 1980s out of Australia and the United Kingdom, both of which have had serious temazepam abuse epidemics and related mortality, have all mostly corroborated each other and proven that the potential for abuse and physical dependence is very high, even in comparison to many other benzodiazepines. As a result, prescriptions for hypnotics such as temazepam have seen a dramatic decrease since 2010, while anxiolytics such as alprazolam (Xanax), clonazepam (Rivitrol, Klonopin), and lorazepam (Ativan) have increased or remained stable. Temazepam and similar hypnotics, such as triazolam (Halcion) are generally reserved for s ...
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Oxazepam
Oxazepam is a short-to-intermediate-acting benzodiazepine. Oxazepam is used for the treatment of anxiety and insomnia and in the control of symptoms of alcohol withdrawal syndrome. It is a metabolite of diazepam, prazepam, and temazepam, and has moderate amnesic, anxiolytic, anticonvulsant, hypnotic, sedative, and skeletal muscle relaxant properties compared to other benzodiazepines. It was patented in 1962 and approved for medical use in 1964. Medical uses It is an intermediate-acting benzodiazepine with a slow onset of action, so it is usually prescribed to individuals who have trouble staying asleep, rather than falling asleep. It is commonly prescribed for anxiety disorders with associated tension, irritability, and agitation. It is also prescribed for drug and alcohol withdrawal, and for anxiety associated with depression. Physicians may use oxazepam outside its approved indications to treat social phobia, post-traumatic stress disorder, insomnia, premenstrual syndrome, a ...
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Cannabis (drug)
Cannabis, also known as marijuana among List of names for cannabis, other names, is a psychoactive drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both Recreational marijuana, recreational and Entheogenic use of cannabis, entheogenic purposes and in various traditional medicines for centuries. Tetrahydrocannabinol (THC) is the main psychoactive component of cannabis, which is one of the 483 known compounds in the plant, including at least 65 other cannabinoids, such as cannabidiol (CBD). Cannabis can be used by Cannabis smoking, smoking, Vaporizer (inhalation device), vaporizing, Cannabis edible, within food, or Tincture of cannabis, as an extract. Cannabis has various effects of cannabis, mental and physical effects, which include euphoria, altered states of mind and Cannabis and time perception, sense of time, difficulty concentrating, Cannabis and memory, impaired short-term memory, impaired motor skill, body mo ...
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Androsterone
Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. It is a weak androgen with a potency that is approximately 1/7 that of testosterone. Androsterone is a metabolite of testosterone and dihydrotestosterone (DHT). In addition, it can be converted back into DHT via 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing conventional intermediates such as androstanedione and testosterone, and as such, can be considered to be a metabolic intermediate in its own right. Androsterone is also known to be an inhibitory androstane neurosteroid, acting as a positive allosteric modulator of the GABAA receptor, and possesses anticonvulsant effects. The unnatural enantiomer of androsterone is more potent as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the natural form. Androsterone's 3β-isomer is epiandrosterone, and its 5β-epimer is etiocholanolone. The ...
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Anabolic Steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone (medication), testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone. They increase protein within cell (biology), cells, especially in skeletal muscles, and also have varying degrees of virilization, virilizing effects, including induction of the development and maintenance of male, masculine secondary sexual characteristics such as the growth of facial hair, facial and body hair. The word ''anabolic'', referring to anabolism, comes from the Greek ἀναβολή ''anabole'', "that which is thrown up, mound". Androgens or AAS are one of three types of sex hormone agonists, the others being estrogen (medication), estrogens like estradiol (medication), estradiol and progestogens like progesterone (medication), progesterone. AAS were synthesized in the 1930s, and are ...
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Drostanolone
Drostanolone, or dromostanolone, is an anabolic–androgenic steroid (AAS) of the dihydrotestosterone (DHT) group which was never marketed. An androgen ester prodrug of drostanolone, drostanolone propionate, was formerly used in the treatment of breast cancer in women under brand names such as Drolban, Masteril, and Masteron. This has also been used non-medically for physique- or performance-enhancing purposes. Pharmacology Pharmacodynamics Like other AAS, drostanolone is an agonist of the androgen receptor (AR). It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity. As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites. While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives. S ...
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Nevada Athletic Commission
The Nevada State Athletic Commission (also known as the Nevada Athletic Commission or NSAC) regulates all contests and exhibitions of unarmed combat within the state of Nevada, including licensure and supervision of promoters, boxers, kickboxers, mixed martial arts fighters, seconds, ring officials, managers, and matchmakers. The commission is the final authority on licensing matters, having the ability to approve, deny, revoke, or suspend all licenses for unarmed combat. The commission was established in 1941. It has several times been criticized for its conduct and sentences, and has several times been labelled a "kangaroo court". Leadership The Nevada State Athletic Commission is an agency of the Nevada Department of Business & Industry and is made up of five part-time commissioners (known as the "Commission"), an executive director, and seven full-time employees. Each commissioner is appointed by the Governor for a three-year term. The Governor also selects one of the five ...
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Diego Brandão
Diego Pereira Brandão (born 27 May 1987) is a Brazilian mixed martial artist currently competing in the Lightweight division. A professional since 2005, he formerly competed for the UFC, RIZIN, and Fight Nights Global. He was the winner of Spike TV's The Ultimate Fighter: Team Bisping vs. Team Miller. Mixed martial arts career Early career Brandão made his MMA debut against Michel Bastos, winning via submission. He went 3-1 before fighting against UFC veteran Ronys Torres. He lost the fight by TKO due to punches. He then fought longtime UFC veteran Brian Foster and won via KO in the first round. Following the contest he won 6 and lost four of his next ten fights, with 3 wins by KO, 2 by submission and 1 by decision, before signing with the UFC. Brandão later became a member of Jackson's MMA in Albuquerque, New Mexico. The Ultimate Fighter In 2011, Brandão signed with the UFC to compete on The Ultimate Fighter: Team Bisping vs. Team Miller. In the first episode, Bran ...
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Jimy Hettes
James Michael Hettes (born June 9, 1987) is a retired American mixed martial artist who competed as a featherweight in the Ultimate Fighting Championship. Background Hettes is a 2-time Keystone State Games Judo Gold Medalist and earned the nickname "Judo Jim" at Greg Jackson's Camp in Albuquerque, NM. Hettes started boxing at age 14 and started training in Brazilian Jiu-Jitsu at the age of 16 and is currently the head instructor at Northeastern Ju-Jitsu in Swoyersville, Pennsylvania. Hettes attended Luzerne County Community College for Criminal Justice. Ultimate Fighting Championship Hettes was originally expected to make his UFC debut in December 2010 as part of The Ultimate Fighter: Team GSP vs. Team Koscheck Finale card; Hettes turned the offer down due to prior engagements with another promotion. On July 16, 2011, Hettes officially signed with the UFC after winning the MMA Melee - MASS Featherweight Championship Belt. As a late replacement to an injured Leonard Garcia. Hett ...
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