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U6 (Berlin U-Bahn) Stations
U6 or U-6 may refer to: * German submarine ''U-6'', one of several German submarines * U6, a railway line on several German underground railway systems: ** U6 U-Bahn line, a line on the Berlin U-Bahn ** U6, a line on the Frankfurt U-Bahn ** U6, a line on the Munich U-Bahn **U6 (Vienna U-Bahn), of the Vienna U-Bahn system. * The IATA airline designator code for Ural Airlines * British NVC community U6, ''Juncus squarrosus'' – ''Festuca ovina'' grassland, one of the calcifugous grassland communities of the British National Vegetation Classification * ''Ultima VI'', a computer role-playing game * U6, a U.S. unemployment statistic - see Unemployment#United States Bureau of Labor statistics * U6 promoter, a gene playing an important role in the synthesis of shRNA *Haplogroup U6 *U6 spliceosomal RNA, a small nuclear RNA component of the spliceosome * US military designation for the DHC-2 Beaver aircraft *Miss Madison, an Unlimited Hydroplane boat that carries the American Power Bo ...
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German Submarine U-6
''U-6'' may refer to one of the following German submarines: * , was a Type U 5 submarine launched in 1910 and served in the First World War until sunk on 15 September 1915 ** During the First World War, Germany also had these submarines with similar names: *** , a Type UB I submarine launched in 1915 and sunk on 18 March 1917 *** , a Type UC I submarine launched in 1915 and sunk on 27 September 1917 * , a Type IIA submarine that served in the Second World War and was stricken on 7 August 1944 * , a Type 205 submarine of the Bundesmarine The German Navy (, ) is the navy of Germany and part of the unified ''Bundeswehr'' (Federal Defense), the German Armed Forces. The German Navy was originally known as the ''Bundesmarine'' (Federal Navy) from 1956 to 1995, when ''Deutsche Mari ... that was launched in 1963 and sold in 1974 ''U-6'' or ''U-VI'' may also refer to: * , a ''U-5'' class submarine of the Austro-Hungarian Navy {{DEFAULTSORT:U-0006 Submarines of Germany ...
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Unemployment
Unemployment, according to the OECD (Organisation for Economic Co-operation and Development), is people above a specified age (usually 15) not being in paid employment or self-employment but currently available for Work (human activity), work during the reference period. Unemployment is measured by the unemployment rate, which is the number of people who are unemployed as a percentage of the labour force (the total number of people employed added to those unemployed). Unemployment can have many sources, such as the following: * new technology, technologies and inventions * the status of the economy, which can be influenced by a recession * competition caused by globalization and international trade * Policy, policies of the government * regulation and market (economics), market Unemployment and the status of the economy can be influenced by a country through, for example, fiscal policy. Furthermore, the monetary authority of a country, such as the central bank, can influ ...
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American Power Boat Association
The American Power Boat Association (APBA) is an American membership-owned corporation. In 1903, New York's Columbia Yacht Club had formulated a constitution for what ultimately became the APBA. It is the United States sanctioning authority for the Union Internationale Motonautique The Union Internationale Motonautique (UIM) is the international governing body of powerboating, based in the Principality of Monaco. It was founded in 1922, in Belgium, as the Union Internationale du Yachting Automobile. History Member nations ..., the world governing body for powerboat racing. Headquartered in Eastpointe Michigan, the APBA has over 3,500 active members and sanctions over 150 races nationwide. The APBA sanctions all types of power boat racing from 205+ mph Unlimited Hydroplanes to smaller Junior Class racing starting at age 9. Hall of Champions Each year, the association inducts powerboat drivers into its "Hall of Champions". *2009 induction *2010 induction Footnotes External ...
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Hydroplane Racing
Hydroplane racing (also known as hydro racing) is a sport involving racing hydroplanes on lakes and rivers. It is a popular spectator sport in several countries. Racing circuits International professional outboard hydroplane racing The Union Internationale Motonautique (or "UIM", headquartered in Europe) sanctions many different hydroplane categories of hydroplane powerboat racing. International UIM F-125, F-250, F-350 and F-500 Circuit powerboat races are very popular in Europe, Asia, and the United States. UIM's O-series hydroplane Formula Circuit racing events are some of the most prestigious Professional Racing Outboard (PRO) hydroplane events in the world. National powerboat racing teams compete for national and international titles in these hydroplane racing circuits. The American Power Boat Association (APBA) sanction similar PRO class national title events in the United States. Professional F-series World Cup Title powerboat races are held at Europe, United States, and wes ...
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Miss Madison
''Miss Madison'' is an H1 Unlimited hydroplane team. It is the only community-owned unlimited hydroplane in the world. It is based out of Madison, Indiana, a small town of 12,000 residents on the Ohio River which annually hosts the Madison Regatta. The story of the boat and city are the subject of the 2001 film ''Madison''. Since late of the 2019 season, they field two boats, the U-6 ''Miss HomeStreet'', and the other the U-91 ''Miss Goodman Real Estate''. History The team was started in 1960 when industrialist Samuel F. Dupont donated one of his hydroplanes to the town in 1961 to be run in the American Power Boat Association races. The town's boat is registered as "U-6" (for APBA Unlimited class, #6) in high-points unlimited hydroplane racing since 1961, which makes them the longest-running team in the sport, although the team will change numbers if required by H1 Unlimited regulations that state the defending national champion use the U-1 designation. Through 2008 the U-6 t ...
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De Havilland Canada DHC-2 Beaver
The de Havilland Canada DHC-2 Beaver is a single-engined high-wing propeller-driven short takeoff and landing (STOL) aircraft developed and manufactured by de Havilland Canada. It has been primarily operated as a bush plane and has been used for a wide variety of utility roles, such as cargo and passenger hauling, aerial application (crop dusting and aerial topdressing), and civil aviation duties. Shortly after the end of the Second World War, de Havilland Canada decided to orient itself towards civilian operators. Based on feedback from pilots, the company decided that the envisioned aircraft should have excellent STOL performance, all-metal construction, and accommodate many features sought by the operators of bush planes. On 16 August 1947, the maiden flight of the aircraft, which had received the designation ''DHC-2 Beaver'', took place. In April 1948, the first production aircraft was delivered to the Ontario Department of Lands and Forests. A Royal New Zealand Air Forc ...
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1962 United States Tri-Service Aircraft Designation System
The Tri-Service aircraft designation system is a unified system introduced in 1962 by the United States Department of Defense for designating all U.S. military aircraft. Previously, the U.S. armed services used separate nomenclature systems. Under the tri-service designation system, officially introduced on 18 September 1962, almost all aircraft receive a unified designation, whether they are operated by the United States Air Force (USAF), United States Navy (USN), United States Marine Corps (USMC), United States Army, or United States Coast Guard (USCG). Experimental aircraft operated by manufacturers or by NASA are also often assigned designations from the X-series of the tri-service system. The 1962 system was based on the one used by the USAF between 1948 and 1962, which was in turn based on the type, model, series USAAS/USAAC/USAAF system used from 1924 to 1948. The 1962 system has been modified and updated since introduction. History The Tri-Service system was first e ...
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U6 Spliceosomal RNA
U6 snRNA is the non-coding small nuclear RNA (snRNA) component of U6 snRNP (''small nuclear ribonucleoprotein''), an RNA-protein complex that combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex that catalyzes the excision of introns from pre-mRNA. Splicing, or the removal of introns, is a major aspect of post-transcriptional modification and takes place only in the nucleus of eukaryotes. The RNA sequence of U6 is the most highly conserved across species of all five of the snRNAs involved in the spliceosome, suggesting that the function of the U6 snRNA has remained both crucial and unchanged through evolution. It is common in vertebrate genomes to find many copies of the U6 snRNA gene or U6-derived pseudogenes. This prevalence of "back-ups" of the U6 snRNA gene in vertebrates further implies its evolutionary importance to organism viability. The U6 snRNA gene has been isolated in many organism ...
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Haplogroup U6
Haplogroup U is a human mitochondrial DNA haplogroup (mtDNA). The clade arose from haplogroup R, likely during the early Upper Paleolithic. Its various subclades (labelled U1–U9, diverging over the course of the Upper Paleolithic) are found widely distributed across Northern and Eastern Europe, Central, Western and South Asia, as well as North Africa, the Horn of Africa, and the Canary Islands. Origins Haplogroup U descends from the haplogroup R mtDNA branch of the phylogenetic tree. The defining mutations (A11467G, A12308G, G12372A) are estimated to have arisen between 43,000 and 50,000 years ago, in the early Upper Paleolithic (around 46,530 ± 3,290 years before present, with a 95% confidence interval per Behar et al., 2012). Ancient DNA classified as belonging to the U* mitochondrial haplogroup has been recovered from human skeletal remains found in Western Siberia, which have been dated to c. 45,000 years ago. The mitogenome (33-fold coverage) of the Peştera Muierii ...
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ShRNA
A short hairpin RNA or small hairpin RNA (shRNA/Hairpin Vector) is an artificial RNA molecule with a tight hairpin turn that can be used to silence target gene expression via RNA interference (RNAi). Expression of shRNA in cells is typically accomplished by delivery of plasmids or through viral or bacterial vectors. shRNA is an advantageous mediator of RNAi in that it has a relatively low rate of degradation and turnover. However, it requires use of an expression vector, which has the potential to cause side effects in medicinal applications. The promoter choice is essential to achieve robust shRNA expression. At first, polymerase III promoters such as U6 and H1 were used; however, these promoters lack spatial and temporal control. As such, there has been a shift to using polymerase II promoters, which are inducible, to regulate shRNA expression. Delivery Expression of shRNA in cells can be obtained by delivery of plasmids or through viral or bacterial vectors. Delivery of ...
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Promotor (biology)
In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may encode a protein (mRNA), or can have a function in and of itself, such as tRNA or rRNA. Promoters are located near the transcription start sites of genes, upstream on the DNA (towards the 5' region of the sense strand). Promoters can be about 100–1000 base pairs long, the sequence of which is highly dependent on the gene and product of transcription, type or class of RNA polymerase recruited to the site, and species of organism. Promoters control gene expression in bacteria and eukaryotes. RNA polymerase must attach to DNA near a gene for transcription to occur. Promoter DNA sequences provide an enzyme binding site. The -10 sequence is TATAAT. -35 sequences are conserved on average, but not in most promoters. Artificial promoters with conserved -10 and -35 elements transcribe more slowly. All D ...
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Ultima VI
''Ultima VI: The False Prophet'', released by Origin Systems in 1990, is the sixth part in the role-playing video game series of '' Ultima''. It is the third and final game in the "Age of Enlightenment" trilogy. ''Ultima VI'' sees the player return to Britannia, at war with a race of gargoyles from another land, struggling to stop a prophecy from ending their race. The player must help defend Britannia against these gargoyles, and ultimately discover the secrets about both lands and its peoples. ''Ultima VI'' continues to advance the technology of the Ultima series. The game world is larger, with a 1024x1024 tile map seamlessly connected and to scale. World interactivity is further increased with object manipulation, movement, and crafting. Graphics and sound are likewise advanced with the use of new sound card technology and VGA graphics cards, and the user interface is streamlined with the use of point-and-click icons. ''Ultima VI'' was followed by '' Ultima VII: The Black Gate ...
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