Tropical Ataxic Neuropathy
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Tropical Ataxic Neuropathy
Tropical ataxic neuropathy (TAN, also known as Strachan-Scott Syndrome and prisoners of war neuropathy) is a disease or category of diseases that commonly causes disability and increases mortality. The causes of TAN are not understood; there is no generally accepted treatment, and the reported outcomes are inconsistent. The disease affects poor tropical populations; there are no good statistics on how many people are affected worldwide, but in some populations, more than a quarter of people are affected. Malnutrition may play a role. Classification and signs and symptoms TAN is one of many tropical myeloneuropathy, tropical myeloneuropathies. It was first described in Jamaica in 1897, by postmortems of 510 cases; in 1959, it was dubbed "tropical ataxic neuropathy". The diagnostic criteria were defined in 1968. TAN is defined by "bilateral optic atrophy, bilateral sensory neural deafness, predominant posterior column involvement, and pyramidal tract myelopathy, with ataxia, ataxic ...
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Tropical Myeloneuropathy
Tropical neuropathy is a class of illnesses with similar signs and symptoms, including konzo, tropical spastic paraparesis (TSP), and tropical ataxic neuropathy (TAN). TAN is poorly understood, and some researchers subdivide it further into separate illnesses. References

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Dysarthria
Dysarthria is a speech sound disorder resulting from neurological injury of the motor component of the motor–speech system and is characterized by poor articulation of phonemes. In other words, it is a condition in which problems effectively occur with the muscles that help produce speech, often making it very difficult to pronounce words. It is unrelated to problems with understanding language (that is, dysphasia or aphasia), although a person can have both. Any of the speech subsystems (respiration, phonation, resonance, prosody, and articulation) can be affected, leading to impairments in intelligibility, audibility, naturalness, and efficiency of vocal communication. Dysarthria that has progressed to a total loss of speech is referred to as anarthria. The term ''dysarthria'' is from New Latin, ''dys-'' "dysfunctional, impaired" and ''arthr-'' "joint, vocal articulation". Neurological injury due to damage in the central or peripheral nervous system may result in weakness ...
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Neglected Tropical Diseases
Neglected tropical diseases (NTDs) are a diverse group of tropical disease, tropical infections that are common in low-income populations in Developing country, developing regions of Africa, Asia, and the Americas. They are caused by a variety of Pathogen, pathogens, such as viruses, bacteria, protozoa, and parasitic worms (helminths). These diseases are contrasted with the "big three" infectious diseases (HIV/AIDS, tuberculosis, and malaria), which generally receive greater treatment and research funding. In sub-Saharan Africa, disease burden, the effect of neglected tropical diseases as a group is comparable to that of malaria and tuberculosis. NTD co-infection can also make HIV/AIDS and tuberculosis more deadly. Some treatments for NTDs are relatively inexpensive. For example, the treatment for schistosomiasis is US$0.20 per child per year. Nevertheless, in 2010 it was estimated that control of neglected diseases would require funding of between US$2 billion and $3  ...
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Tropical Spastic Paraparesis
Tropical spastic paraparesis (TSP), is a medical condition that causes weakness, muscle spasms, and sensory disturbance by human T-lymphotropic virus resulting in paraparesis, weakness of the legs. As the name suggests, it is most common in tropical regions, including the Caribbean. Blood transfusion products are screened for human T-lymphotropic virus 1 (HTLV-1) antibodies, as a preventive measure. Signs and symptoms Some of the signs of Tropical spastic paraparesis are: :::::::*Leg instability :::::::*Urinary dysfunction. :::::::*Bowel dysfunction :::::::*Back pain :::::::*Erectile problems :::::::*Psoriasis Individuals with TSP may also exhibit uveitis (inflammation of the uveal tract of the eye), arthritis (inflammation of one or more joints), pulmonary lymphocytic alveolitis (inflammation of the lung tissues), polymyositis (an inflammatory muscle disease), keratoconjunctivitis sicca (persistent dryness of the cornea and conjunctiva), and infectious dermatitis (inflammation ...
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Lathyrism
Lathyrism is a condition caused by eating certain legumes of the genus ''Lathyrus''. There are three types of lathyrism: ''neurolathyrism'', ''osteolathyrism'', and ''angiolathyrism'', all of which are incurable, differing in their symptoms and in the body tissues affected. Neurolathyrism is the type associated with the consumption of legumes in the genus ''Lathyrus'' that contain the toxin ODAP. ODAP ingestion results in motorneuron death. The result is paralysis and muscle atrophy of the lower limbs. Osteolathyrism, a different type of lathyrism, affects the connective tissues, not the motorneurons. Osteolathyrism results from the ingestion of ''Lathyrus odoratus'' seeds (sweet peas), and is often referred to as odoratism. It is caused by a different toxin, beta-aminopropionitrile, which affects the linking of the subunits of collagen, a major structural protein found in connective tissue. A third type of lathyrism is angiolathyrism, which is similar to osteolathyrism in its ...
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Konzo
Konzo is an epidemic paralytic disease occurring among hunger-stricken rural populations in Africa where a diet dominated by insufficiently processed cassava results in simultaneous malnutrition and high dietary cyanide intake. Konzo was first described by Giovanni Trolli in 1938 who compiled the observations from eight doctors working in the Kwango area of the Belgian Congo (now Democratic Republic of the Congo). Signs and symptoms The onset of paralysis ( spastic paraparesis) is sudden and symmetrical and affects the legs more than the arms. The resulting disability is permanent but does not progress. Typically, a patient is standing and walking on the balls of the feet with rigid legs and often with ankle clonus. Initially, most patients experience generalized weakness during the first days and are bedridden for some days or weeks before trying to walk. Occasional blurred vision and/or speech difficulties typically clear during the first month, except in severely affected p ...
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Prisoners Of War
A prisoner of war (POW) is a person who is held Captivity, captive by a belligerent power during or immediately after an armed conflict. The earliest recorded usage of the phrase "prisoner of war" dates back to 1610. Belligerents hold prisoners of war in custody for a range of legitimate and illegitimate reasons, such as isolating them from the enemy combatants still in the field (releasing and Repatriation, repatriating them in an orderly manner after hostilities), demonstrating military victory, punishing them, prosecuting them for war crimes, exploitation of labour, exploiting them for their labour, recruiting or even Conscription, conscripting them as their own combatants, collecting military and political intelligence from them, or Indoctrination, indoctrinating them in new political or religious beliefs. Ancient times For most of human history, depending on the culture of the victors, enemy fighters on the losing side in a battle who had surrendered and been taken as ...
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Cassava
''Manihot esculenta'', common name, commonly called cassava (), manioc, or yuca (among numerous regional names), is a woody shrub of the spurge family, Euphorbiaceae, native to South America. Although a perennial plant, cassava is extensively cultivated as an annual agriculture, crop in tropical and subtropical regions for its edible starchy tuberous root, a major source of carbohydrates. Though it is often called ''yuca'' in parts of Spanish America and in the United States, it is not related to yucca, a shrub in the family Asparagaceae. Cassava is predominantly consumed in boiled form, but substantial quantities are used to extract cassava starch, called tapioca, which is used for food, animal feed, and industrial purposes. The Brazilian farinha, and the related ''garri'' of West Africa, is an edible coarse flour obtained by grating cassava roots, pressing moisture off the obtained grated pulp, and finally drying it (and roasting both in the case of farinha and garri). Cassav ...
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Temperate
In geography, the temperate climates of Earth occur in the middle latitudes (23.5° to 66.5° N/S of Equator), which span between the tropics and the polar regions of Earth. These zones generally have wider temperature ranges throughout the year and more distinct seasonal changes compared to tropical climates, where such variations are often small and usually only have precipitation changes. In temperate climates, not only do latitudinal positions influence temperature changes, but sea currents, prevailing wind direction, continentality (how large a landmass is) and altitude also shape temperate climates. The Köppen climate classification defines a climate as "temperate" C, when the mean temperature is above but below in the coldest month to account for the persistency of frost. However, other climate classifications set the minimum at . Zones and climates The north temperate zone extends from the Tropic of Cancer (approximately 23.5° north latitude) to the Arctic ...
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Guiana
The Guianas, sometimes called by the Spanish loan-word ''Guayanas'' (''Las Guayanas''), is a region in north-eastern South America which includes the following three territories: * French Guiana, an overseas department and region of France * Guyana, formerly known as British Guiana from 1831 until 1966, after the colonies of Berbice, Essequibo, and Demerara, taken from the Netherlands in 1814, were merged into a single colony * Suriname, formerly Dutch Guiana, until 1814 together with Berbice, Essequibo and Demerara In the wider context, the Guianas also includes the following two territories: * Guayana Region in eastern Venezuela ( Amazonas, Bolívar, and Delta Amacuro states), formerly the Guayana Province, alternatively known as Spanish Guayana * State of Amapá in northern Brazil, known as Portuguese Guiana (or Brazilian Guiana) History Pre-colonial period Before the arrival of European colonials, the Guianas were populated by scattered bands of native Arawak ...
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Hypophonia
Hypophonia is soft speech, especially resulting from a lack of coordination in the vocal musculature. This condition is a common presentation in Parkinson's disease. This condition is generally treated with voice training programs, use of shorter sentences, breathing exercises, and muscle training exercises for vocal cords. Further research Doctors at the Indiana University of Pennsylvania Indiana University of Pennsylvania (IUP) is a public research university in Indiana County, Pennsylvania. As of fall 2021, the university enrolled 7,044 undergraduates and 1,865 postgraduates, for a total enrollment of 9,009 students. The univ ... have proposed a novel treatment for hypophonic voice: Twang therapy. References Symptoms and signs: Speech and voice Parkinson's disease {{med-sign-stub ...
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Dysphonia
A hoarse voice, also known as dysphonia or hoarseness, is when the voice involuntarily sounds breathy, raspy, or strained, or is softer in volume or lower in pitch. A hoarse voice, can be associated with a feeling of unease or scratchiness in the throat. Hoarseness is often a symptom of problems in the vocal folds of the larynx. It may be caused by laryngitis, which in turn may be caused by an upper respiratory infection, a cold, or allergies. Cheering at sporting events, speaking loudly in noisy situations, talking for too long without resting one's voice, singing loudly, or speaking with a voice that's too high or too low can also cause temporary hoarseness. A number of other causes for losing one's voice exist, and treatment is generally by resting the voice and treating the underlying cause. If the cause is misuse or overuse of the voice, drinking plenty of water may alleviate the problems. It appears to occur more commonly in females and the elderly. Furthermore, certain occup ...
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