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Trional
Trional (Methylsulfonal) is a sedative-hypnotic and anesthetic drug with GABAergic actions. It has similar effects to sulfonal, except it is faster acting. History Trional was prepared and introduced by Eugen Baumann and Alfred Kast in 1888. Appeared in Agatha Christie's "Murder on the Orient Express", "And Then There Were None" and other novels such as John Bude’s “The Lake District Murder” as a sleep inducing sedative, and in In Search of Lost Time (Sodom and Gomorrah) by Marcel Proust as a hypnotic. Sax Rohmer Arthur Henry "Sarsfield" Ward (15 February 1883 – 1 June 1959), better known as Sax Rohmer, was an English novelist. He is best remembered for his series of novels featuring the master criminal Dr. Fu Manchu."Rohmer, Sax" by Jack Adrian in Da ... also references trional in his novel '' Dope''. See also * Sulfonal * Tetronal References Hypnotics GABAA receptor positive allosteric modulators Sulfones {{sedative-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetronal
Tetronal is a sedative-hypnotic and anesthetic drug with GABAergic action Action may refer to: * Action (narrative), a literary mode * Action fiction, a type of genre fiction * Action game, a genre of video game Film * Action film, a genre of film * ''Action'' (1921 film), a film by John Ford * ''Action'' (1980 fil ...s. It is not as effective as trional. History Tetronal was introduced by Eugen Baumann and Alfred Kast in 1888. See also * Sulfonal * Trional References Hypnotics Sulfones GABAA receptor positive allosteric modulators {{sedative-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulfonal
Sulfonmethane (Sulfonomethane, Sulfonal, Acetone diethyl sulfone) is a chemical compound first synthesized by Eugen Baumann in 1888 and introduced as a hypnotic drug by Alfred Kast later on, but now superseded by newer and safer sedatives. Its appearance is either in colorless crystalline or powdered form. In United States, it is scheduled as a Schedule III drug in the Controlled Substance Act. Effects It produces lengthened sleep in functional nervous insomnia, and is also useful in insanity, being given with mucilage of acacia or in hot liquids, owing to its insolubility, or in large capsules. Its hypnotic power is not equal to that of chloral, but as it is not a depressant to the heart or respiration it can be used when morphine or chloral are contra-indicated. It is, however, very uncertain in its action, often failing to produce sleep when taken at bedtime, but producing drowsiness and sleep the following day. The drowsiness the next day following a medicinal dose can b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulfonal
Sulfonmethane (Sulfonomethane, Sulfonal, Acetone diethyl sulfone) is a chemical compound first synthesized by Eugen Baumann in 1888 and introduced as a hypnotic drug by Alfred Kast later on, but now superseded by newer and safer sedatives. Its appearance is either in colorless crystalline or powdered form. In United States, it is scheduled as a Schedule III drug in the Controlled Substance Act. Effects It produces lengthened sleep in functional nervous insomnia, and is also useful in insanity, being given with mucilage of acacia or in hot liquids, owing to its insolubility, or in large capsules. Its hypnotic power is not equal to that of chloral, but as it is not a depressant to the heart or respiration it can be used when morphine or chloral are contra-indicated. It is, however, very uncertain in its action, often failing to produce sleep when taken at bedtime, but producing drowsiness and sleep the following day. The drowsiness the next day following a medicinal dose can b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eugen Baumann
Eugen Baumann (12 December 1846 – 3 November 1896) was a German chemist. He was one of the first people to create polyvinyl chloride (PVC), and, together with Carl Schotten, he discovered the Schotten-Baumann reaction. Life Baumann was born in Cannstatt, which is now part of Stuttgart. After he attended a gymnasium in Stuttgart, he was educated in the pharmacy of his father. During his time in Stuttgart, he attended the lectures of Hermann von Fehling at the University of Stuttgart. To broaden his education, he went to Lübeck and Gothenburg to work in pharmacies there. Later, he studied pharmacy at the University of Tübingen. He passed his first exam in 1870 and received his PhD in 1872 for work with Felix Hoppe-Seyler. He followed Hoppe-Seyler to the University of Straßburg where did his habilitation in 1876. The same year, Emil Heinrich Du Bois-Reymond offered him a position as the Head of the Chemistry Department of the Institute of Physiology in Berlin. In 1882, Bauman ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sedative-hypnotic
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but the majority of them affect the neurotransmitter gamma-aminobutyric acid (GABA). In spite of the fact that each sedative acts in its own way, most produce relaxing effects by increasing GABA activity. This group is related to hypnotics. The term ''sedative'' describes drugs that serve to calm or relieve anxiety, whereas the term ''hypnotic'' describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness) they are often referred to collectively as ''sedative-hypnotic'' drugs. Sedatives can be used to produce an overly-calming effect (alcohol being the most ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marcel Proust
Valentin Louis Georges Eugène Marcel Proust (; ; 10 July 1871 – 18 November 1922) was a French novelist, critic, and essayist who wrote the monumental novel ''In Search of Lost Time'' (''À la recherche du temps perdu''; with the previous English title translation of ''Remembrance of Things Past''), originally published in French in seven volumes between 1913 and 1927. He is considered by critics and writers to be one of the most influential authors of the 20th century. Background Proust was born on 10 July 1871 at the home of his great-uncle in the Paris Borough of Auteuil (the south-western sector of the then-rustic 16th arrondissement), two months after the Treaty of Frankfurt formally ended the Franco-Prussian War. His birth took place at the very beginning of the Third Republic, during the violence that surrounded the suppression of the Paris Commune, and his childhood corresponded with the consolidation of the Republic. Much of ''In Search of Lost Time'' concerns the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypnotics
Hypnotic (from Greek ''Hypnos'', sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia to produce and maintain unconsciousness, "sleep" is metaphorical as there are no regular sleep stages or cyclical natural states; patients rarely recover from anesthesia feeling refreshed and with renewed energy. The word is also used in art.) and to treat insomnia (sleeplessness). This group of drugs is related to sedatives''. ''Whereas the term sedative describes drugs that serve to calm or relieve anxiety, the term hypnotic generally describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness), they are often referred to collectively as sedative-hyp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dope (novel)
''Dope'' is a 1919 novel by Sax Rohmer set in the Limehouse area of London. It is not a Fu Manchu novel, and concerns itself with cannabis rather than opium. It is based on the story of Billie Carleton, a young English actress whose scandalous lifestyle ended with her death from a drug overdose in 1918. Adaptations The novel was adapted into comics by Trina Robbins between 1981 and 1983 in ''Eclipse Magazine'' and '' Eclipse Monthly''. IDW Publishing published a collected edition of this work in 2017, with a postface by John B. Cooke. See also * List of works by Sax Rohmer References External links * Dope: Sax Rohmerat the Internet Archive The Internet Archive is an American digital library with the stated mission of "universal access to all knowledge". It provides free public access to collections of digitized materials, including websites, software applications/games, music, ... Sax Rohmer's Dopegraphic novel on Google Books * Novels adapted into comics Nov ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sax Rohmer
Arthur Henry "Sarsfield" Ward (15 February 1883 – 1 June 1959), better known as Sax Rohmer, was an English novelist. He is best remembered for his series of novels featuring the master criminal Dr. Fu Manchu."Rohmer, Sax" by Jack Adrian in David Pringle, ''St. James Guide to Horror, Ghost & Gothic Writers''. London: St. James Press, 1998; (pp. 482–484). Life and work Born in Birmingham to working class Irish parents William Ward (c. 1850–1932), a clerk, and Margaret Mary (née Furey; c. 1850–1901), Arthur Ward initially pursued a career as a civil servant before concentrating on writing full-time. He worked as a poet, songwriter and comedy sketch writer for music hall performers before creating the Sax Rohmer persona and pursuing a career writing fiction. Like his contemporaries Algernon Blackwood and Arthur Machen, Rohmer claimed membership to one of the factions of the qabbalistic Hermetic Order of the Golden Dawn. Rohmer also claimed ties to the Rosicrucians, but ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypnotic
Hypnotic (from Greek ''Hypnos'', sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia to produce and maintain unconsciousness, "sleep" is metaphorical as there are no regular sleep stages or cyclical natural states; patients rarely recover from anesthesia feeling refreshed and with renewed energy. The word is also used in art.) and to treat insomnia (sleeplessness). This group of drugs is related to sedatives''. ''Whereas the term sedative describes drugs that serve to calm or relieve anxiety, the term hypnotic generally describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness), they are often referred to collectively as sedative-h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Lake District Murder
''The Lake District Murder'' is a 1935 detective novel by the British writer John Bude.Hubin p.56 It is the first in a series of novels featuring Chief Inspector Meredith, promoted at the end of case to Superintendent. Set in the Lake District of Northern England, it shows the influence of Freeman Wills Crofts's Inspector French novels by featuring a detective who methodically breaks down the alibis of his suspects. In 2014 it was reissued by the British Library Publishing as part of a group of republished crime novels from the Golden Age of Detective Fiction. Synopsis The body of a man is found at the lonely filling station in Cumbria where he is a partner, asphyxiated by petrol fumes. It is at first taken to be suicide until several discrepancies prompt the police to take a closer look. Meredith and his colleagues begin to suspect that the dead man has been silenced by his associates in some elaborate criminal scheme using a series of petrol Gasoline (; ) or petrol (; ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Search Of Lost Time
''In Search of Lost Time'' (french: À la recherche du temps perdu), first translated into English as ''Remembrance of Things Past'', and sometimes referred to in French as ''La Recherche'' (''The Search''), is a novel in seven volumes by French author Marcel Proust. This early 20th-century work is his most prominent, known both for its length and its theme of involuntary memory. The most famous example of this is the "episode of the madeleine", which occurs early in the first volume. The novel gained fame in English in translations by C. K. Scott Moncrieff and Terence Kilmartin as ''Remembrance of Things Past'', but the title ''In Search of Lost Time'', a literal rendering of the French, became ascendant after D. J. Enright adopted it for his revised translation published in 1992. ''In Search of Lost Time'' follows the narrator's recollections of childhood and experiences into adulthood in the late 19th-century and early 20th-century high-society France, while reflecting on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
