Toxocaridae
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Toxocaridae
The Toxocaridae are a zoonotic family Family (from la, familia) is a Social group, group of people related either by consanguinity (by recognized birth) or Affinity (law), affinity (by marriage or other relationship). The purpose of the family is to maintain the well-being of its ... of parasitic nematodes that infect canids and felids and which cause toxocariasis in humans (visceral larva migrans and ocular larva migrans). The worms are unable to reproduce in humans. Notable species include: *''Toxocara canis'', which infects dogs. *''Toxocara cati'', which infects cats and lacks intermediate hosts. *''Toxascaris leonina'', which infects mostly cats, but also dogs. *''Toxocara malayasiensis'', which infects cats. *''Toxocara vitulorum'', which infects buffalo and cattle. Infection Infection by ''T. canis'' or ''T. cati'' can cause various clinical manifestations. One of these is visceral larva migrans, wherein the larvae are unable to develop in humans as they do in ca ...
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Ascaridida
The order Ascaridida includes several families of parasitic roundworms with three "lips" on the anterior end. They were formerly placed in the subclass Rhabditia by some, but morphological and DNA sequence data rather unequivocally assign them to the Spiruria. The Oxyurida and Rhigonematida are occasionally placed in the Ascaridida as superfamily Oxyuroidea, but while they seem indeed to be Spiruria, they are not as close to ''Ascaris'' as such a treatment would place them.Tree of Life Web Project (ToL) (2002)Nematoda Version of 2002-JAN-01. Retrieved 2008-NOV-02. These "worms" contain a number of important parasites of humans and domestic animals. Important families include: * The Anisakidae are also called the "marine mammal ascarids". The larvae of these worms cause anisakiasis when ingested by humans in raw or insufficiently cooked fish, but do not reproduce in humans. * The Ascarididae include the giant intestinal roundworms (''Ascaris'' spp.). * The Cosmocercidae include ...
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Toxascaris Leonina
''Toxascaris leonina'' is a common parasitic roundworm found in dogs, cats, foxes, and related host species. ''T. leonina'' is an ascarid nematode, a worldwide distributed helminth parasite which is in a division of eukaryotic parasites that, unlike external parasites such as lice and fleas, live inside their host. The definitive hosts of ''T. leonina'' include canids (dogs, foxes, etc.) and felines (cats), while the intermediate hosts are usually rodents, such as mice or rats. Infection occurs in the definitive host when the animal eats an infected rodent. While ''T. leonina'' can occur in either dogs or cats, it is far more frequent in cats. A coprolite containing ''T. leonina'' eggs was excavated in Argentina's Catamarca Province and dated to 17002–16573 years old. This finding indicates that ''T. leonina'' has existed in South America since at least the Late Pleistocene. Life cycle The life cycle of ''T. leonina'' is fairly simple. Eggs are ingested and hatch in t ...
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Toxocara Vitulorum
''Toxocara vitulorum'' is a species of nematode belonging to the family Toxocaridae. The species has cosmopolitan distribution. References Ascaridida {{Improve categories, date=February 2022 ...
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Retinoblastoma
Retinoblastoma (Rb) is a rare form of cancer that rapidly develops from the immature cells of a retina, the light-detecting tissue of the eye. It is the most common primary malignant intraocular cancer in children, and it is almost exclusively found in young children. Though most children survive this cancer, they may lose their vision in the affected eye(s) or need to have the eye removed. Almost half of children with retinoblastoma have a hereditary genetic defect associated with retinoblastoma. In other cases, it is caused by a congenital mutation in the chromosome 13 gene 13q14 (retinoblastoma protein). Signs and symptoms Retinoblastoma is universally known as the most intrusive intraocular cancer among children. The chance of survival and preservation of the eye depends fully on the severity. Retinoblastoma is extremely rare as there are only about 200 to 300 cases every year in the United States. Looking at retinoblastoma globally, only 1 in about 15,000 children have ...
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Parasitic Nematodes Of Mammals
Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson has characterised parasites as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes. There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), trophicallytransmitted parasitism (by being eaten), vector-transmitted parasitism, parasitoidism, and micropredation. One major axis of classification concerns invasiveness: an endoparasite lives inside the host's body; an ect ...
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Toxocariasis
Toxocariasis is an illness of humans caused by the dog roundworm (''Toxocara canis'') and, less frequently, the cat roundworm (''Toxocara cati'').https://academic.oup.com/ajcp/article/142/suppl_1/A104/1771175 Eosinophilic Pseudoleukemia Due to Toxocariasis in a 3-year-old Patient: Report of A Rare Case These are the most common intestinal roundworms of dogs, coyotes, wolves and foxes and domestic cats, respectively. Humans are among the many "accidental" or paratenic hosts of these roundworms. While this zoonotic infection is usually asymptomatic, it may cause severe disease. There are three distinct syndromes of toxocariasis: ''covert toxocariasis'' is a relatively mild illness very similar to Löffler's syndrome. It is characterized by fever, eosinophilia, urticaria, enlarged lymph nodes, cough, bronchospasm, wheezing, abdominal pain, headaches, and/or hepatosplenomegaly. ''Visceral larva migrans'' (VLM) is a more severe form of the disease; signs and symptoms depend on the spe ...
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Eosinophil
Eosinophils, sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells (WBCs) and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. They form about 2 to 3% of WBCs. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such ...
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Atopy
Atopy is the tendency to produce an exaggerated immunoglobulin E (IgE) immune response to otherwise harmless substances in the environment. Allergic diseases are clinical manifestations of such inappropriate, atopic responses. Atopy may have a hereditary component, although contact with the allergen or irritant must occur before the hypersensitivity reaction can develop (characteristically after re-exposure). Maternal psychological trauma ''in utero'' may also be a strong indicator for development of atopy. The term ''atopy'' was coined by Arthur F. Coca and Robert Cooke in 1923. Many physicians and scientists use the term "atopy" for any IgE-mediated reaction (even those that are appropriate and proportional to the antigen), but many pediatricians reserve the word "atopy" for a genetically mediated predisposition to an excessive IgE reaction. The term is from Greek ἀτοπία meaning "the state of being out of place", "absurdity". Signs and symptoms Atopic sensitization ...
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Mebendazole
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections, hydatid disease, and giardia, among others. It is taken by mouth. Mebendazole is usually well tolerated. Common side effects include headache, vomiting, and ringing in the ears. If used at large doses it may cause bone marrow suppression. It is unclear if it is safe in pregnancy. Mebendazole is a broad-spectrum antihelminthic agent of the benzimidazole type. Mebendazole came into use in 1971, after it was developed by Janssen Pharmaceutica in Belgium. It is on the World Health Organization's List of Essential Medicines. Mebendazole is available as a generic medication. Medical use Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations, including roundworm, hookworm, whipworm, threadworm (pinw ...
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Albendazole
Albendazole (also known as albendazolum) is a broad-spectrum anthelmintic and antiprotozoal agent of the benzimidazole type. It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases. Common side effects include nausea, abdominal pain, and headache. Rare but potentially serious side effects include bone marrow suppression which usually improves on discontinuing the medication. Liver inflammation has been reported and those with prior liver problems are at greater risk. It is pregnancy category C in the United States and category D in Australia, meaning it may cause harm if taken by pregnant women. Albendazole was developed in 1975. It is on the World Health Organization's List of Essential Medicines. Medical uses Albendazole is an effective tr ...
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Companion Animal Parasite Council
The Companion Animal Parasite Council (CAPC, commonly pronounced "Cap-Cee") is a non-profit organization (501c3) composed of practicing veterinarians, academic veterinary parasitologists, veterinary technicians, state public health veterinarians, and staff from the Centers for Disease Control and Prevention who are dedicated to reducing the numbers of parasites in dogs and cats along with reducing the risk of transmitting these parasites and diseases to humans. The group is sponsored mainly by industrial sponsors that are devoted to maintaining the health of pets through improved parasiticides and diagnostics that can be used by practitioners and clients in a safe and consumer-friendly manner. Academic Veterinary Parasitologists * Dr. Byron Blagburn, Auburn University * Dr. Dwight D. Bowman, Cornell University * Dr. Michael Yabsley, University of Georgia * Dr. Heather Walden, University of Florida Practitioners * Dr. Jay Stewart, Oregon * Dr. Craig Prior, Tennessee * Dr. Rick ...
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