Timeline Of Senescence Research
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Timeline Of Senescence Research
This timeline lists notable events in the history of research into senescence or biological aging, including the research and development of life extension methods, brain aging delay methods and rejuvenation. People have long been interested in making their lives longer and healthier. The most anсient Egyptian, Indian and Chinese books contain reasoning about aging. Ancient Egyptians used garlic in large quantities to extend their lifespan. Hippocrates (), in his ''Aphorisms'', and Aristotle (384 – 322 BC), in '' On youth and old age'', expressed their opinions about reasons for old age and gave advice about lifestyle. Medieval Persian physician Ibn Sina ( – 1037), known in the West as Avicenna, summarized the achievements of earlier generations about this issue. Background Descriptions of rejuvenation and immortality remedies are often found in the writings of alchemists. But all those remedies did not allow even alchemists themselves to live l ...
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Senescence
Senescence () or biological aging is the gradual deterioration of functional characteristics in living organisms. The word ''senescence'' can refer to either cellular senescence or to senescence of the whole organism. Organismal senescence involves an increase in death rates and/or a decrease in fecundity with increasing age, at least in the latter part of an organism's life cycle. Senescence is the inevitable fate of almost all multicellular organisms with germ-soma separation, but it can be delayed. The discovery, in 1934, that calorie restriction can extend lifespan by 50% in rats, and the existence of species having negligible senescence and potentially immortal organisms such as '' Hydra'', have motivated research into delaying senescence and thus age-related diseases. Rare human mutations can cause accelerated aging diseases. Environmental factors may affect aging – for example, overexposure to ultraviolet radiation accelerates skin aging. Different parts of the body ...
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Terentia
Terentia (; 98 BC – AD 6) was the wife of the renowned orator Marcus Tullius Cicero. She was instrumental in Cicero's political life both as a benefactor and as a fervent activist for his cause. Family background Terentia was born into a wealthy plebeian family by the name of Terentius. She may have been a daughter of the Terentii Varrones, who were the most important senatorial branch of that family. This is suggested by the fact that Cicero had a cousin with the cognomen Varro and a friend by the name of Marcus Terentius Varro. This Varro owned a house near Arpinum not far from Cicero's own birthplace. Therefore, if Terentia was indeed the daughter of a Varro, Cicero's links to this family may have influenced his marriage to Terentia. Terentia had one half-sister named Fabia, who was a Vestal Virgin and the daughter of a patrician named Fabius. If Terentia's mother married the plebeian Terentius first, then Terentia was the older sister and probably the sole inheritor of he ...
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259 BC
__NOTOC__ Year 259 BC was a year of the pre-Julian Roman calendar. At the time it was known as the Year of the Consulship of Scipio and Florus (or, less frequently, year 495 ''Ab urbe condita''). The denomination 259 BC for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Seleucid Empire * The Seleucid king Antiochus II starts the Second Syrian War against Ptolemy II Philadelphus to avenge his father's losses. Antiochus II finds a willing ally in Antigonus II Gonatas, the king of Macedonia, who has been dealing with Ptolemy II's attempts to destabilize Macedonia. Sicily * The Carthaginians under Hamilcar take advantage of their victory at Thermae in Sicily by counterattacking the Romans and seizing Enna. Hamilcar continues south to Camarina, in Syracusan territory, to try to convince the Syracusans to rejoin the Carthaginian side. China * The State of Zh ...
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