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Timeline Of Senescence Research
This timeline lists notable events in the history of research into senescence or biological aging, including the research and development of life extension methods, brain aging delay methods and rejuvenation. People have long been interested in making their lives longer and healthier. The most anсient Egyptian, Indian and Chinese books contain reasoning about aging. Ancient Egyptians used garlic in large quantities to extend their lifespan. Hippocrates (), in his ''Aphorisms'', and Aristotle (384 – 322 BC), in '' On youth and old age'', expressed their opinions about reasons for old age and gave advice about lifestyle. Medieval Persian physician Ibn Sina ( – 1037), known in the West as Avicenna, summarized the achievements of earlier generations about this issue. Background Descriptions of rejuvenation and immortality remedies are often found in the writings of alchemists. But all those remedies did not allow even alchemists themselves to live l ...
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Senescence
Senescence () or biological aging is the gradual deterioration of functional characteristics in living organisms. The word ''senescence'' can refer to either cellular senescence or to senescence of the whole organism. Organismal senescence involves an increase in death rates and/or a decrease in fecundity with increasing age, at least in the latter part of an organism's life cycle. Senescence is the inevitable fate of almost all multicellular organisms with germ-soma separation, but it can be delayed. The discovery, in 1934, that calorie restriction can extend lifespan by 50% in rats, and the existence of species having negligible senescence and potentially immortal organisms such as '' Hydra'', have motivated research into delaying senescence and thus age-related diseases. Rare human mutations can cause accelerated aging diseases. Environmental factors may affect aging – for example, overexposure to ultraviolet radiation accelerates skin aging. Different parts of the body ...
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Terentia
Terentia (; 98 BC – AD 6) was the wife of the renowned orator Marcus Tullius Cicero. She was instrumental in Cicero's political life both as a benefactor and as a fervent activist for his cause. Family background Terentia was born into a wealthy plebeian family by the name of Terentius. She may have been a daughter of the Terentii Varrones, who were the most important senatorial branch of that family. This is suggested by the fact that Cicero had a cousin with the cognomen Varro and a friend by the name of Marcus Terentius Varro. This Varro owned a house near Arpinum not far from Cicero's own birthplace. Therefore, if Terentia was indeed the daughter of a Varro, Cicero's links to this family may have influenced his marriage to Terentia. Terentia had one half-sister named Fabia, who was a Vestal Virgin and the daughter of a patrician named Fabius. If Terentia's mother married the plebeian Terentius first, then Terentia was the older sister and probably the sole inheritor of he ...
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259 BC
__NOTOC__ Year 259 BC was a year of the pre-Julian Roman calendar. At the time it was known as the Year of the Consulship of Scipio and Florus (or, less frequently, year 495 ''Ab urbe condita''). The denomination 259 BC for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Seleucid Empire * The Seleucid king Antiochus II starts the Second Syrian War against Ptolemy II Philadelphus to avenge his father's losses. Antiochus II finds a willing ally in Antigonus II Gonatas, the king of Macedonia, who has been dealing with Ptolemy II's attempts to destabilize Macedonia. Sicily * The Carthaginians under Hamilcar take advantage of their victory at Thermae in Sicily by counterattacking the Romans and seizing Enna. Hamilcar continues south to Camarina, in Syracusan territory, to try to convince the Syracusans to rejoin the Carthaginian side. China * The State of Zh ...
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350 BC
__NOTOC__ Year 350 BC was a year of the pre-Julian Roman calendar. At the time it was known as the Year of the Consulship of Laenas and Scipio (or, less frequently, year 404 ''Ab urbe condita''). The denomination 350 BC for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Persian Empire * Sidon, the centre of the revolt against Persia, seeks help from its sister city of Tyre and from Egypt but gets very little. * Idrieus, the second son of Hecatomnus, succeeds to the throne of Caria on the death of Artemisia II, the widow of his elder brother Mausolus. Shortly after his accession, at the request of the Persian king, Artaxerxes III, Idrieus equips a fleet of 40 triremes and assembles an army of 8,000 mercenary troops and despatches them against Cyprus, under the command of the Athenian general Phocion. Greece * Alexander I becomes king of Epirus after hi ...
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Biomedical Technology
Biomedical technology is the application of engineering and technology principles to the domain of living or biological systems, with an emphasis on human health and diseases. Biomedical engineering and Biotechnology alike are often loosely called ''Biomedical Technology'' or Bioengineering. The Biomedical technology field is currently growing at a rapid pace. Required jobs for the industry expect to grow 23% by 2024, and with the pay averaging over $86,000. Biomedical technology involves: * Biomedical science * Biomedical informatics * Biomedical research * Biomedical engineering * Bioengineering * Biotechnology Biomedical technologies: * Cloning ** Therapeutic cloning In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. The technique consists of taking an enucleated oocyte (egg cell) and implantin ... {{col-end References Biological engineering ...
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CIA World Factbook
''The World Factbook'', also known as the ''CIA World Factbook'', is a reference resource produced by the Central Intelligence Agency (CIA) with almanac-style information about the countries of the world. The official print version is available from the Government Publishing Office. The ''Factbook'' is available in the form of a website that is partially updated every week. It is also available for download for use off-line. It provides a two- to three-page summary of the demographics, geography, communications, government, economy, and military of each of 267 international entities including U.S.-recognized countries, dependencies, and other areas in the world. ''The World Factbook'' is prepared by the CIA for the use of U.S. government officials, and its style, format, coverage, and content are primarily designed to meet their requirements. However, it is frequently used as a resource for academic research papers and news articles. As a work of the U.S. government, it is i ...
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Monaco
Monaco (; ), officially the Principality of Monaco (french: Principauté de Monaco; Ligurian: ; oc, Principat de Mónegue), is a sovereign city-state and microstate on the French Riviera a few kilometres west of the Italian region of Liguria, in Western Europe, on the Mediterranean Sea. It is bordered by France to the north, east and west. The principality is home to 38,682 residents, of whom 9,486 are Monégasque nationals; it is widely recognised as one of the most expensive and wealthiest places in the world. The official language of the principality is French. In addition, Monégasque (a dialect of Ligurian), Italian and English are spoken and understood by many residents. With an area of , it is the second-smallest sovereign state in the world, after Vatican City. Its make it the most densely-populated sovereign state in the world. Monaco has a land border of and the world's shortest coastline of approximately ; it has a width that varies between . The hig ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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List Of Countries By Life Expectancy
Methodology The life expectancy is shown separately for males and for females, as well as a combined figure. Several non- sovereign entities and territories are also included in this list. The figures reflect the quality of healthcare in the countries listed as well as other factors including ongoing wars, obesity, and HIV infections. From the beginning of the current century there is a tendency to also estimate Healthy life expectancy (HALE) — the average number of years that a person can expect to live in "full health". Comparing life expectancies across countries can be problematic. For example, due to poor reporting in some countries and various local standards in collecting statistics. This is especially true for Healthy life expectancy, the definition of which criteria may change over time, even within a country. World Bank Group (2020) Data of the World Bank Group for 2020. The values in the World Bank Group tables are rounded. All calculations were done on ...
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The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, review articles ("seminars" and "reviews"), editorials, book reviews, correspondence, as well as news features and case reports. ''The Lancet'' has been owned by Elsevier since 1991, and its editor-in-chief since 1995 has been Richard Horton. The journal has editorial offices in London, New York City, and Beijing. History ''The Lancet'' was founded in 1823 by Thomas Wakley, an English surgeon who named it after the surgical instrument called a lancet (scalpel). Members of the Wakley family retained editorship of the journal until 1908. In 1921, ''The Lancet'' was acquired by Hodder & Stoughton. Elsevier acquired ''The Lancet'' from Hodder & Stoughton in 1991. Impact According to the ''Journal Citation Reports'', the journal has a 202 ...
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Leonard Hayflick
Leonard Hayflick (born 20 May 1928) is a Professor of Anatomy at the UCSF School of Medicine, and was Professor of Medical Microbiology at Stanford University School of Medicine. He is a past president of the Gerontological Society of America and was a founding member of the council of the National Institute on Aging (NIA). The recipient of a number of research prizes and awards, including the 1991 Sandoz Prize for Gerontological Research, he has studied the senescence, aging process for more than fifty years. He is known for discovering that normal human Cell (biology), cells divide for a limited number of times ''in vitro'' (refuting the contention by Alexis Carrel that normal body cells are biological immortality, immortal). This is known as the Hayflick limit. His discoveries overturned a 60-year old dogma that all cultured cells are immortal. Hayflick demonstrated that normal cells have a memory and can remember at what doubling level they have reached. He demonstrated that hi ...
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Series A
A series A round (also known as series A financing or series A investment) is the name typically given to a company's first significant round of venture capital financing. The name refers to the class of preferred stock sold to investors in exchange for their investment. It is usually the first series of stock after the common stock and common stock options issued to company founders, employees, friends and family and angel investors. Series A rounds are traditionally a critical stage in the funding of new companies. Series A investors typically purchase 10% to 30% of the company. The capital raised during a series A is usually intended to capitalize the company for 6 months to 2 years as it develops its products, performs initial marketing and branding, hires its initial employees, and otherwise undertakes early stage business operations. It may be followed by more rounds ( Series B, Series C, etc). Sources of capital Because there are no public exchanges listing their securi ...
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